Abstract：
:Hyaline joint cartilage has only a limited potential for self-repair. Some of the published techniques for osteochondral defect therapy try to improve that potential. In this study, it was hypothesised that one of those surgical techniques, the crushed transplanted bone graft together with a collagen membrane, accelerates significantly the reconstruction of the subchondral bone plate and improves the mechanical and histological quality of repaired cartilage in osteochondral defects compared to an empty control defect. In order to test this hypothesis, defects were created in the left knee of 12 sheep and filled either with autologous crushed bone graft or left empty. The animals were sacrificed after 3 (n = 6) and 6 (n = 6) months. No differences were found either macroscopically or histomorphometrically between the bone graft and empty control defects. The biomechanical as well as the histological results of the bone graft defects were inferior to the control defects with inflammatory processes caused either by bone graft or membrane remnants. Based on the results in this sheep model, the filling of subchondral bone defects with compacted cancellous bone should be carefully reconsidered.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Schell H,Lienau J,Kleemann RU,Schlichting K,Taylor WR,Weiler A,Duda GNdoi
10.1016/j.jbiomech.2007.02.021subject
Has Abstractpub_date
2007-01-01 00:00:00pages
S64-72eissn
0021-9290issn
1873-2380pii
S0021-9290(07)00086-3journal_volume
40 Suppl 1pub_type
杂志文章abstract：:Continuous flow blood fraction separators are used to facilitate the removal of specific blood components for donation or for certain medical procedures. Problems with one such device, the IBM 2997 Blood Processor, have been noted in a number of independent investigations. A key feature of this particular unit is a ce...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(86)90163-6
更新日期：1986-01-01 00:00:00
abstract：:Falls are common and potentially disastrous for older adults. A novel approach that could augment current fall prevention procedures is to teach older adults movement strategies to reduce the risk of injury. The purpose of the study was to determine whether older adults can learn a movement strategy ("tuck-and-roll") ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.12.002
更新日期：2019-01-23 00:00:00
abstract：:Cancellous bone architecture and mechanics are intimately related. The trabecular architecture of cancellous bone is considered determined by its mechanical environment (Wolff's law), and the mechanical properties of cancellous bone are inversely determined by the trabecular architecture and material properties. Much ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(96)00177-7
更新日期：1997-05-01 00:00:00
abstract：:Patellofemoral pain is common amongst recreational runners and associated with altered running kinematics. However, it is currently unclear how sex may influence kinematic differences previously reported in runners with patellofemoral pain. This case-control study aimed to evaluate lower limb kinematics in males and f...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.05.014
更新日期：2019-06-25 00:00:00
abstract：:An apparatus was designed for mechanical compression of cultured articular cartilage explants with acylindrical plain-ended loading head (diameter 2-5 mm) driven by a stepping motor. A load cell under the culture dish was applied for feedback regulation utilizing a microprocessor-based control unit. The operating prog...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(89)90232-7
更新日期：1989-01-01 00:00:00
abstract：:Head injury is a persistent and costly problem for both children and adults. Globally, approximately 10 million people are hospitalized each year for head injuries. Knowing the structural properties of the head is important for modeling the response of the head in impact, and for providing insights into mechanisms of ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.08.024
更新日期：2015-11-05 00:00:00
abstract：:Stress is one of the many biological factors that plays an important role in wound healing. It is therefore essential to analyze stresses around the wound closure theoretically, especially when no invasive/noninvasive technique to measure stress directly is available. The objective of this paper is to determine the re...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(00)00160-3
更新日期：2001-01-01 00:00:00
abstract：:Deformation and loading of the knee posterior joint capsule were studied in the cat, in extension rotations and in axial external (ER) and internal (IR) rotations at full extension. Loads were measured in the ligament along the upper edge of the capsule, using mechanically sensitive neurons that were calibrated as loa...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(93)90352-f
更新日期：1993-11-01 00:00:00
abstract：:Individual differences in bone mass distribution at the proximal femur may be determined by daily weight-bearing physical activity (PA) since bone self-adapts according to the mechanical loads that is submitted. The aim of this study was to analyse computationally the effect of different weight-bearing PA types in the...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2013.06.031
更新日期：2013-09-03 00:00:00
abstract：:The process of collecting ground reaction force data by mounting a forceplate beneath a treadmill belt has the advantage that numerous walking trials can be analyzed without the problem of subjects 'targeting' their footsteps. However, a potential problem is that the measured forces represent a summation of bilateral ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(93)90020-f
更新日期：1993-04-01 00:00:00
abstract：PURPOSE:The accuracy of biomechanical models is predicated on the realism by which they represent their biomechanical tissues. Unfortunately, most models use phenomenological ligament models that neglect the behaviour in the failure region. Therefore, the purpose of this investigation was to test whether a mechanistic ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2017.06.039
更新日期：2017-08-16 00:00:00
abstract：:There appears a linear relationship between small increases in running speed and cardiovascular health benefits. Encouraging or coaching recreational runners to increase their running speed to derive these health benefits might be more effective if their joint level kinematic and kinetic strategy was understood. The a...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.02.010
更新日期：2018-04-11 00:00:00
abstract：:The purpose of this study was to examine the age-related predictive and feedback adaptive locomotor improvements in the components of dynamic stability control during disturbed walking. Thirteen old (62-74 yrs) and ten young (23-30 yrs) male subjects performed a gait protocol on a gangway, which included one covered e...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.04.025
更新日期：2010-08-26 00:00:00
abstract：:Recent studies raised increasing concern about the reliability of computer models in reproducing in vivo hemodynamics in cerebral aneurysms. Boundary condition problem is among the most frequently addressed issues since three-dimensional (3-D) modeling is usually restricted to local arterial segments. The present stud...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.09.031
更新日期：2016-11-07 00:00:00
abstract：:A sticky chain model has been proposed to describe the unfolding of spectrin network under applied mechanical loads. With the model, the response of a red blood cell (RBC) under static and cyclic shear loading has been predicted, which agrees qualitatively with relevant experimental results. ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.05.028
更新日期：2008-08-07 00:00:00
abstract：:In this study we investigated the time course of length and velocity of muscle fascicles and tendinous tissues (TT) during isometric twitch contraction, and examined how their interaction relates to the time course of external torque and muscle fascicle force generation. From seven males, supra-maximal twitch contract...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.03.023
更新日期：2007-01-01 00:00:00
abstract：:A squeeze-film lubrication model of the human ankle joint in standing that takes into account the fluid transport across the articular surface is presented. Articular cartilage is a biphasic mixture of the ideal interstitial fluid and an elastic permeable isotropic homogeneous intrinsically incompressible matrix. The ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(00)00109-3
更新日期：2000-11-01 00:00:00
abstract：:Current neck injury criteria are based on structural failure of the spinal (vertebral) column without consideration of injury to the spinal cord. Since one of the primary functions of the vertebral column is to protect the cord, it stands to reason that a more refined measure of neck injury threshold would be the onse...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2012.11.012
更新日期：2013-02-22 00:00:00
abstract：:As a support to the tooth, the mechanical response of the periodontal ligament (PDL) is complex. Like other connective tissues, the PDL exhibits non-linear and time-dependent behavior. The viscoelasticity of the PDL plays a significant role in low and high loading rates. Little information, however, is available on th...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.02.020
更新日期：2016-03-21 00:00:00
abstract：:Two questions were addressed in this study: (1) how much strain of the superficial aponeurosis of the human medial gastrocnemius muscle (MG) was obtained during voluntary isometric contractions in vivo, (2) whether there existed inhomogeneity of the strain along the superficial aponeurosis. Seven male subjects, whose ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(01)00196-8
更新日期：2002-02-01 00:00:00
abstract：:An arterial graft with a corrugated cylindrical cross-section has been proposed as a partial solution to the problem of elastic stiffness mismatch between conventional grafts and arterial tissue (Trescony et al., 1994, US Patent 5,282, 847 (granted February 1 1994)). A two-dimensional ring theory model and a finite el...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(98)00084-0
更新日期：1998-08-01 00:00:00
abstract：:Muscle fatigue and recovery are complex processes influencing muscle force generation capacity. While fatigue reduces this capacity, recovery acts to restore the unfatigued muscle state. Many factors can potentially affect muscle recovery, and among these may be a task dependency of recovery following an exercise. How...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.11.061
更新日期：2017-01-25 00:00:00
abstract：:Fixation failure of glenoid components is the main cause of unsuccessful total shoulder arthroplasties. The characteristics of these failures are still not well understood, hence, attempts at improving the implant fixation are somewhat blind and the failure rate remains high. This lack of understanding is largely due ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.10.019
更新日期：2010-03-03 00:00:00
abstract：:Human cortical bone fracture toughness depends on the anatomical locations under quasi-static loading. Recent results also showed that under fall-like loading, cortical bone fracture toughness is similar at different anatomical locations in the same donor. While cortical bone toughening mechanisms are known to be depe...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.01.008
更新日期：2019-03-06 00:00:00
abstract：:Tendon elasticity is important for economical locomotion; however it is unknown whether tendon stiffness is appropriate to achieve an optimal efficiency in various muscles. Here we test the hypothesis that the Achilles tendon is of an appropriate stiffness to maximise medial gastrocnemius muscle efficiency during loco...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2006.07.025
更新日期：2007-01-01 00:00:00
abstract：:The relative motion of the brain with respect to the skull has been widely studied to investigate brain injury mechanisms under impacts, but the motion patterns are not yet thoroughly understood. This work analyzes brain motion patterns using the most recent and advanced experimental relative brain/skull motion data c...
journal_title：Journal of biomechanics
pub_type： 杂志文章,评审
doi：10.1016/j.jbiomech.2006.06.018
更新日期：2007-01-01 00:00:00
abstract：:The objective of this work is to gain more insight into the processes of oral perception of food texture. Particularly, the limits for detectable thickness differences of objects, which are evaluated in the human mouth, are investigated. In a sensory study small, flexible circular disks (diameter in mm range) of varyi...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.04.012
更新日期：2007-01-01 00:00:00
abstract：:Human responses are critical to understanding injury biomechanics in blunt ballistic impacts, which are defined as 20-200 g projectiles impacting at 20-250 m/s. 13 human cadavers were exposed to three distinct ballistic impacts of the chest to determine force-time, deflection-time and force-deflection responses. Compa...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(03)00238-0
更新日期：2004-01-01 00:00:00
abstract：:This study sought to gain insights into the steps leading to remineralization and mechanical recovery of hydrated dentin. Mechanical recovery in water was hypothesized to result from effective mineral matrix binding and to occur from the innermost regions outwards due to an increase in the number of nucleation sites. ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.09.005
更新日期：2011-01-04 00:00:00
abstract：:Range of motion (ROM) of the thoracic spine has implications in patient discrimination for diagnostic purposes and in biomechanical models for predictions of spinal loads. Few previous studies have reported quite different thoracic ROMs. Total (T1-T12), lower (T5-T12) and upper (T1-T5) thoracic, lumbar (T12-S1), pelvi...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.09.003
更新日期：2016-04-11 00:00:00
