Abstract：
:Continuous flow blood fraction separators are used to facilitate the removal of specific blood components for donation or for certain medical procedures. Problems with one such device, the IBM 2997 Blood Processor, have been noted in a number of independent investigations. A key feature of this particular unit is a ceramic rotary seal that allows the continuous separation by centrifugation to take place. The equation of motion for flow inside a split toroid cavity within the rotary seal has been solved numerically; velocities and shear stresses found numerically compare favorably with limiting case, analytical solutions. Predicted torque values as a function of rotation rate and fluid viscosity also served as an experimental check on the validity of the mathematical findings. Comparison of calculated shear stress levels and exposure times with known thresholds for cell damage shows that platelet and leukocyte losses may indeed be caused by the seal. Suggestions are made to improve performance of the IBM Blood Processor.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Harvey CB,O'Rear EAdoi
10.1016/0021-9290(86)90163-6subject
Has Abstractpub_date
1986-01-01 00:00:00pages
579-87issue
8eissn
0021-9290issn
1873-2380pii
0021-9290(86)90163-6journal_volume
19pub_type
杂志文章abstract：:Distal biceps tendon ruptures have been reported to be associated with narrowing of the proximal radioulnar space. There have been no studies that three-dimensionally measured the distance between the bicipital tuberosity and the proximal ulna during active motion. The purpose of this study was to three-dimensionally ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.110120
更新日期：2020-12-02 00:00:00
abstract：:Many clinical studies suggest that local blood flow patterns are involved in the location and development of atherosclerosis. In coronary diseases, this assumption should be corroborated by quantitative information on local hemodynamic parameters such as pressure, velocity or wall shear stress. Nowadays, computational...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(02)00179-3
更新日期：2002-10-01 00:00:00
abstract：:Mechanical fatigue of bone cement leading to damage accumulation is implicated in the loosening of cemented hip components. Even though cracks have been identified in autopsy-retrieved mantles, damage accumulation by continuous growth and increase in number of microcracks has not yet been demonstrated experimentally. ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00018-4
更新日期：1999-05-01 00:00:00
abstract：:There is a paucity of data in the literature on the restraining effects of the glenohumeral (GH) ligaments; cadaveric testing is one of the best methods for determining the function of these types of tissues. The aim of this work was to commission a custom-made six degrees of freedom (dof) joint loading apparatus and ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.03.007
更新日期：2009-06-19 00:00:00
abstract：:Experimental tests, such as the confined and unconfined compression and the indentation tests, are traditionally used to determine the poroelastic properties of hydrated soft tissues (HSTs). The purpose of this study was to quantitatively evaluate the reliability of H(A) and K values as identified from experimental co...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.02.020
更新日期：2007-01-01 00:00:00
abstract：:Platelet activation under blood flow is thought to be critically dependent on the autologous secretion of soluble platelet agonists (chemical activators) such as ADP and thromboxane. However, recent evidence challenging this model suggests that platelet activation can occur independent of soluble agonist signalling, i...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2011.02.006
更新日期：2011-04-07 00:00:00
abstract：:This paper presents a practical and effective approach to the calibration of instrumented spatial linkages for biomechanical applications. A 6-DOF mechanical linkage with rotational transducers is designed and in-house manufactured for this purpose. In order to assess the validity of the proposed calibration technique...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2006.06.021
更新日期：2007-01-01 00:00:00
abstract：:This study proposed a revision to the Rosenstein's method of numerical calculation of the largest Lyapunov exponent (LyE) to make it more robust to noise. To this aim, the effect of increasing number of initial neighboring points on the LyE value was investigated and compared to values obtained by filtering the time s...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.01.013
更新日期：2019-03-06 00:00:00
abstract：:A continuous wave technique is described for measuring the nine independent orthotropic elastic coefficients from a single cubic specimen. The side dimensions of this cubic specimen are on the order of 5 mm. Because of the small size of the specimen, the spatial resolution of material inhomogeneity using this techniqu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(84)90029-0
更新日期：1984-01-01 00:00:00
abstract：:Cellular mechanotransduction is an integral part of many crucial physiological processes, but non-invasive tools for quantifying intracellular strain in vivo are not available for complex tissues such as bone. As a first step to address this gap, we have utilized a novel, non-invasive approach to quantify cellular str...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.08.023
更新日期：2016-10-03 00:00:00
abstract：:Healthy humans display a preference for walking at a stride frequency dependent on the inertial properties of their legs. Walking at preferred stride frequency (PSF) is predicted to maximize local dynamic stability, whereby sensitivity to intrinsic perturbations arising from natural variability inherent in biological ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2013.10.012
更新日期：2014-01-03 00:00:00
abstract：:Stress, strain and modulus are regularly used to characterize material properties of tissue samples. However, when comparing results from different studies it is evident the reported material properties, particularly failure strains, vary hugely. The aim of our study was to characterize how and why specimen length and...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.04.040
更新日期：2010-08-26 00:00:00
abstract：:Various foot structures are thought to influence forefoot plantar pressures during walking. High peak plantar pressures (PPP) during walking in people with diabetes mellitus (DM) and peripheral neuropathy (PN) can cause skin breakdown. The question addressed by this study is "What are the primary forefoot structural f...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/s0021-9290(03)00078-2
更新日期：2003-07-01 00:00:00
abstract：:The aim of cryosurgery is to kill cells within a closely defined region maintained at a predetermined low temperature. To effectively kill cells, it is important to be able to predict and control the cooling rate over some critical range of temperatures and freezing states in order to regulate the spatial extent of in...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2005.11.005
更新日期：2007-01-01 00:00:00
abstract：:The aims of this study were: 1. To study the transfer of energy between the high bar and the gymnast. 2. To develop criteria from the utilisation of high bar elasticity and the utilisation of muscle capacity to assess the effectiveness of a movement solution. 3. To study the influence of varying segment movement upon ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(98)00134-1
更新日期：1998-12-01 00:00:00
abstract：:The purpose of this study was to predict and explain the pattern of shear force and ligament loading in the ACL-deficient knee during walking, and to compare these results to similar calculations for the healthy knee. Musculoskeletal modeling and computer simulation were combined to calculate ligament forces in the AC...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2003.07.001
更新日期：2004-03-01 00:00:00
abstract：:When running, energy is lost during stance to redirect the center of mass of the body (COM) from downwards to upwards. The present study uses a collision-based approach to analyze how these energy losses change with slope and speed. Therefore, we evaluate separately the average collision angle, i.e. the angle of devia...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.12.024
更新日期：2019-01-23 00:00:00
abstract：:The purpose of the study was to evaluate the rates of change in the estimated masses and principal moments of inertia of the body segments during the second and third trimesters of pregnancy. Fifteen subjects, on average 15.1 weeks pregnant, were tested monthly until term. The body was modelled as 16 segments consisti...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(95)00042-9
更新日期：1996-02-01 00:00:00
abstract：:Bone represents a porous tissue containing a fluid phase, a solid matrix, and cells. Movement of the fluid phase within the pores or spaces of the solid matrix translates endogenous and exogenous mechanobiological, biochemical and electromechanical signals from the system that is exposed to the dynamic external enviro...
journal_title：Journal of biomechanics
pub_type： 杂志文章,评审
doi：10.1016/s0021-9290(03)00123-4
更新日期：2003-10-01 00:00:00
abstract：:A general theory is described for deriving the mechanical effect of muscles with large attachment sites. In a cadaver experiment the complete attachment sites and bundle distribution of 16 muscles of the shoulder mechanism were recorded. These data were used to calculate the mechanical effect, i.e. the resulting force...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(91)90007-a
更新日期：1991-01-01 00:00:00
abstract：:As human breast tissue is continuously deformed by gravity, it is difficult to identify the non-loaded neutral breast position from which to take measurements. To estimate the neutral nipple position, this study proposed a simple novel method to counteract the three dimensional effect of gravity on the breast using th...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.10.012
更新日期：2016-12-08 00:00:00
abstract：:The principal motivation for the present work was the study of the kinetics of anaerobic metabolism. A new mathematical model of the bioenergetics of sprinting, incorporating a three-equation representation of anaerobic metabolism, is developed. Results computed using the model are compared with measured data from the...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(00)00035-x
更新日期：2000-08-01 00:00:00
abstract：:Several motion capture methods exist for predicting hip joint centers (HJC). These methods include regression models, functional joints, and projections from greater trochanters. While regression and functional methods have been compared to imaging techniques, the TROCH method has not been previously validated. The pu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.06.013
更新日期：2016-09-06 00:00:00
abstract：:The methods of evaluation of mechanical energy economy during human movement based on the calculation of three different values of work (Wwb, Ww, Wn), corresponding to three hypothetical types of energy exchange, are subject to criticism. Only the value of work, Wwb, calculated under the assumption of energy transfers...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(86)90006-0
更新日期：1986-01-01 00:00:00
abstract：:The purpose of this study was to determine failure stresses and failure lengths of actively and passively stretched myofibrils. As expected, myofibrils failed at average sarcomere lengths (about 6-7μm) that vastly exceeded sarcomere lengths at which actin-myosin filament overlap ceases to exist (4μm) and thus actin-my...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.07.016
更新日期：2010-11-16 00:00:00
abstract：:Musculo-skeletal modeling could play a key role in advancing our understanding of the healthy and pathological spine, but the credibility of such models are strictly dependent on the accuracy of the anatomical data incorporated. In this study, we present a complete and coherent musculo-skeletal dataset for the thoraci...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2017.04.003
更新日期：2017-06-14 00:00:00
abstract：:In this study, we tested the compressive stress relaxation behaviors of the mandibular condylar and temporal cartilages in the porcine temporomandibular joint (TMJ). The aim was to determine the quantitative and qualitative similarities and differences of compressive stress relaxation behaviors between the two cartila...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.03.007
更新日期：2014-05-07 00:00:00
abstract：:Strain shielding, a mechanical effect occurring in structures combining stiff with more flexible materials, is considered to lead to a reduction of density in bone surrounding the implant. This effect can be related to the weakness of the implant fixation, which can promote implant loosening. Several studies describe ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.09.048
更新日期：2010-02-10 00:00:00
abstract：:The purpose of this study was to employ subject-specific computer models to evaluate the interaction of glenohumeral range-of-motion and Hill-Sachs humeral head bone defect size on engagement and shoulder dislocation. We hypothesized that the rate of engagement would increase as defect size increased, and that greater...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.11.001
更新日期：2016-02-29 00:00:00
abstract：:There are almost no published data that describe the creep behavior of trabecular bone (at the specimen level), even though the creep behavior of cortical bone has been well documented. In an effort to characterize the creep behavior of trabecular bone and to compare it with that of cortical bone, we performed uniaxia...
journal_title：Journal of biomechanics
pub_type： 杂志文章,评审
doi：10.1016/0021-9290(94)90006-x
更新日期：1994-03-01 00:00:00
