Abstract：
:The nucleotide sequence of the gene encoding chicken ribosomal protein L7a was determined. The gene contains eight exons and seven introns, which spread over 3613 nucleotides. The transcription initiation sites were located on four consecutive nucleotides GCCC, which are at the 5' terminus of a short polypyrimidine tract of eight base-pairs flanked by G + C-rich regions. Neither a canonical TATA nor a CAAT box was found in the 5'-flanking region. Instead, a short A + T-rich stretch was found at the position where the TATA box is expected to be. There is an intensive nuclear protein binding motif repeated four times in the region -134 to -50. This motif is common to many ribosomal protein genes and may play an important role in the control of ribosomal protein gene expression.
journal_name
Biochimiejournal_title
Biochimieauthors
Maeda N,Kenmochi N,Tanaka Tdoi
10.1016/0300-9084(93)90128-fsubject
Has Abstractpub_date
1993-01-01 00:00:00pages
785-90issue
9eissn
0300-9084issn
1638-6183pii
0300-9084(93)90128-Fjournal_volume
75pub_type
杂志文章相关文献
BIOCHIMIE文献大全abstract：:The exosome is a complex of eleven subunits in yeast, involved in RNA processing and degradation. Despite the extensive in vivo functional studies of the exosome, little information is yet available on the structure of the complex and on the RNase and RNA binding activities of the individual subunits. The current mode...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2007.01.011
更新日期：2007-05-01 00:00:00
abstract：:Insect prophenoloxidase (PPO) is an essential innate immunity protein to induce pathogen into melanization. In Bombyx mori, pro-phenoloxidase-activating enzyme (PPAE) can directly cleave and activate PPO. However, PPO in Manduca sexta cannot be cleaved into active phenoloxidase (PO) by serine proteases unless cofactor...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2014.03.007
更新日期：2014-07-01 00:00:00
abstract：:Pulmonary fibrosis (PF) is a progressive lethal disorder. In this study, the effect of daidzein, a soyisoflavone against Bleomycin (BLM) induced PF in rats was elucidated. A single intratracheal instillation of BLM (3 U/kg.bw) was administered in rats to induce PF. Daidzein (0.2 mg/kg) was administered subcutaneously,...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2014.04.005
更新日期：2014-08-01 00:00:00
abstract：:Microalgae are single-cell, photosynthetic organisms whose biodiversity places them at the forefront of biological producers of high-value molecules including lipids and pigments. Some of these organisms particular are capable of synthesizing n-3 very long chain polyunsaturated fatty acids (VLC-PUFAs), known to have b...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/j.biochi.2020.04.022
更新日期：2020-11-01 00:00:00
abstract：:TcrX/Y is one of the twelve two component system (TCS) present in Mycobacterium tuberculosis. We have investigated the TcrX/Y interaction by in silico studies, pull down assay, radioactive phosphotransfer, surface plasmon resonance as well as crosstalk analysis of TcrY with TcrA - a non-cognate response regulator. Seq...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2009.11.009
更新日期：2010-03-01 00:00:00
abstract：:Bothropstoxin-I (BthTx-I) is a homodimeric Lys49-PLA2 from the venom of the snake Bothrops jararacussu, which lacks hydrolytic activity against phospholipid substrates, yet permeabilizes membranes by a Ca2+-independent mechanism. The interaction of the BthTx-I with model membranes has been studied by intrinsic tryptop...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2007.10.012
更新日期：2008-09-01 00:00:00
abstract：:A methylene group of camphor is hydroxylated by a P450 monoxygenase system containing in addition to the cytochrome and flavoprotein dehydrogenase a two-iron, two-sulfur redox protein termed putidaredoxin. The regulatory control of electron transport equilibrium occurs via ligation of substrate and redoxin to the cyto...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(76)80364-1
更新日期：1976-01-01 00:00:00
abstract：:Binding of indoloquinolines with different aliphatic side chains to a parallel G-quadruplex derived from the MYC promoter sequence was characterized by optical and calorimetric measurements. ITC experiments performed at different temperatures enabled the determination of molar heat capacity changes upon quadruplex bin...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2018.11.015
更新日期：2019-02-01 00:00:00
abstract：:Nanoluciferase (NanoLuc) is a newly developed small luciferase reporter with the brightest bioluminescence reported to date. In the present work, we developed NanoLuc as a novel quantitative protein fusion tag for efficient overexpression in Escherichia coli and ultrasensitive bioluminescent assays using human leukemi...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2014.08.012
更新日期：2014-11-01 00:00:00
abstract：:A novel bgl1 gene, encoding GH3 family β-glucosidase from Penicillium verruculosum (PvBGL), was cloned and heterologously expressed in P. canescens RN3-11-7 (niaD-) strain under the control of the strong xylA gene promoter. The recombinant rPvBGL was purified and their properties were studied in comparison with those ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2019.11.009
更新日期：2020-01-01 00:00:00
abstract：:The eukaryotic ribosomal protein S15 is a key component of the decoding site in contrast to its prokaryotic counterpart, S19p, which is located away from the mRNA binding track on the ribosome. Here, we determined the oligopeptide of S15 neighboring the A site mRNA codon on the human 80S ribosome with the use of mRNA ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2010.02.031
更新日期：2010-07-01 00:00:00
abstract：:A series of halomethylated derivatives of dihydrocoumarins has been found to inhibit irreversibly proteases and esterases. alpha-Chymotrypsin, subtilish, elastase are rapidly inactivated in the presence of these compounds, while trypsin, kallicrein, papain are inhibited more slowly. Esterases like acetylcholinesterase...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(77)80140-5
更新日期：1977-01-01 00:00:00
abstract：:Our understanding of plant meiosis is rapidly increasing thanks to the model Arabidopsis thaliana. Here we present the results of a screening for meiotic mutants carried out with a library containing 30,719 T-DNA insertion lines. An average of one mutant per 1000 lines was recovered. Several phenotypic classes could b...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(01)01348-7
更新日期：2001-11-01 00:00:00
abstract：:Alteration of the epigenome is associated with a wide range of human diseases. Therefore, deciphering the pathways that regulate the epigenetic modulation of gene expression is a major milestone for the understanding of diverse biological mechanisms and subsequently human pathologies. Although often evoked, little is ...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/j.biochi.2007.07.022
更新日期：2008-01-01 00:00:00
abstract：:Peptidase family S46 consists of two types of dipeptidyl-peptidases (DPPs), DPP7 and DPP11, which liberate dipeptides from the N-termini of polypeptides along with the penultimate hydrophobic and acidic residues, respectively. Their specificities are primarily defined by a single amino acid residue, Gly673 in DPP7 and...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2017.10.015
更新日期：2018-04-01 00:00:00
abstract：:Kinetic parameters characterizing the catalytic activities of enzymes are typically investigated in dilute solutions. However, in reality, these reactions occur in cells that, in addition to water and ions, are full of other macromolecules including proteins, nucleic acids, lipids, and metabolites. Such a crowded envi...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2020.07.009
更新日期：2020-09-01 00:00:00
abstract：:Synthesis and secretion of polysaccharides by Gram-negative bacteria are a result of a concerted action of enzymatic and channel-forming proteins localized in different compartments of the cell. The presented work comprises functional characterization of PssO protein encoded within the previously identified, chromosom...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2008.08.004
更新日期：2008-11-01 00:00:00
abstract：:At least 6 N-acetylglucosaminyltransferases (GlcNAc-T I, II, III, IV, V and VI) are involved in initiating the synthesis of the various branches found in complex asparagine-linked oligosaccharides (N-glycans), as indicated below: GlcNAc beta 1-6 GlcNAc-T V GlcNAc beta 1-4 GlcNAc-T VI GlcNAc beta 1-2Man alpha 1-6 GlcNA...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(88)90289-1
更新日期：1988-11-01 00:00:00
abstract：:Explants from 7, 8, 9, 11, 13-day chick embryonic skin incorporating (3H) Uridine for different periods 1 hr, 3 or 4 hr and a chase with actinomycin) are studied with respect to free (F) or membrane bound (B) cytoplasmic polysomes and to RNA extracted from them. Polysome specific activity decreases at older stages but...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(76)80226-x
更新日期：1976-01-01 00:00:00
abstract：:Split luciferase complementary assay has been used to investigate the effect of WD domain deletion on Apaf-1 oligomerization. Apaf-1 is an adaptor molecule in formation of apoptosome that activates caspase-9, an activation that is a key event in the mitochondrial cell death pathway. Structural studies suggest that nor...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2020.10.013
更新日期：2021-01-01 00:00:00
abstract：:A new apolipoprotein has been identified in VHDL1 and in HDL. This protein is immunologically distinct from already isolated apoproteins. It was isolated by column chromatography on hydroxylapatite. In polyacrylamide gel electrophoresis, its mobility is very close to that of apo D. The amino acid composition differs f...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(78)80199-0
更新日期：1978-01-01 00:00:00
abstract：:Directed mutagenesis has been used to study the nicotinamide subsite of the glycolytic NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Residue Asn313 is involved together with the carboxyamide moiety of the nicotinamide ring in a complex network of hydrogen bonding interactions which fix the position o...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(90)90119-2
更新日期：1990-08-01 00:00:00
abstract：:Mouse brain myelin consists of a continuum of particles of different densities, as shown by sucrose density gradient centrifugation. In normal animals most of the material (65 per cent) is concentrated between 0.6 and 0.7 M sucrose (the maximum being found at 0.66 M sucrose, corresponding to 23 per cent). The density ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(77)80213-7
更新日期：1977-01-01 00:00:00
abstract：:The recF gene of E coli lies within a cluster of genes which play essential roles in DNA replication; the gene order is dnaA dnaN recF gyrB. Each of these genes has its own promoters which, with the exception of dnaA promoters, reside entirely within the translated region of the respective preceding gene. In this repo...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(91)90220-u
更新日期：1991-02-01 00:00:00
abstract：:The possibility that brown adipose tissue thermogenesis can be recruited in order to combat the development of obesity has led to a high interest in the identification of "browning agents", i.e. agents that increase the amount and activity of UCP1 in brown and brite/beige adipose tissues. However, functional analysis ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2017.01.007
更新日期：2017-03-01 00:00:00
abstract：:Hydroxylamine and its derivatives of general formula H2NOR react with aldehydes and aldimines to produce oximes. If R corresponds to the side chain of a natural amino acid, such compounds can be thought of as analogs of the corresponding amino acids, lacking the alpha-carboxylate group. Oximes formed between such comp...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(89)90175-2
更新日期：1989-04-01 00:00:00
abstract：:In order to identify conserved potential secondary structures within translational start sites, mRNA sequences derived from different species were studied with programs able to depict such features. The potential secondary structure of 71 bases around the initiator AUG or AUGs in the coding sequences of 290 eukaryotic...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(94)90120-1
更新日期：1994-01-01 00:00:00
abstract：:Human mitochondrial diseases, defined as the diseases due to a mitochondrial oxidative phosphorylation defect, represent a large group of very diverse diseases with respect to phenotype and genetic causes. They present with many unsolved issues, the comprehensive analysis of which is beyond the scope of this review. W...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/j.biochi.2013.08.012
更新日期：2014-05-01 00:00:00
abstract：:Conformational flexibility and structural fluctuations play an important role in enzyme activity. A great variety of internal motions ranging over different time scales and of different amplitudes are involved in the catalytic cycle. These different types of motions and their functional consequences are considered in ...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/s0300-9084(98)80054-0
更新日期：1998-01-01 00:00:00
abstract：:Datura stramonium contains a compound that impairs learning retention in mice. It has been purified to homogeneity and its structure has been established as that of a gamma-L-glutamyl-L-aspartate. The biological activity of this pseudodipeptide has been found to be identical with that of the corresponding synthetic on...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(88)90183-6
更新日期：1988-09-01 00:00:00
