Abstract:
:It is known that the ingestion of cooked meat which contains carcinogenic heterocyclic amines causes increase in urinary mutagenicity in humans. Using 6 healthy non-smokers, we examined the effect of 3-week oral administration of Lactobacillus casei (bacilli commonly present in yoghurt), on the urinary mutagenicity derived from ingestion of fried ground beef. Comparison of the urinary mutagenicity found before and after the L. casei treatment showed that the treatment resulted in a decrease (6-67%, average 47.5%) of the mutagenicity. This suppressing effect is possibly related to the changes in the intestinal microflora population.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Hayatsu H,Hayatsu Tdoi
10.1016/0304-3835(93)90261-7subject
Has Abstractpub_date
1993-09-30 00:00:00pages
173-9issue
2-3eissn
0304-3835issn
1872-7980pii
0304-3835(93)90261-7journal_volume
73pub_type
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