Residential radon and small cell lung cancer. A systematic review.

Abstract:

:Residential radon exposure is considered the second cause of lung cancer and the first in never smokers. Nevertheless, the association between the different histological types of lung cancer and radon is not completely clear, and radon effect on small cell lung cancer is not completely understood. We aim to asses the effect of residential radon exposure on the risk of small cell lung cancer (SCLC) in general population and miners through a systematic review applying predefined inclusion and exclusion criteria. 16 studies were included. Most of them point to a relationship between indoor radon and SCLC, though some investigations show no association. When comparing the risk of SCLC due to radon exposure with NSCLC, it can be observed that an increased risk for SCLC is present. Small cell lung cancer seems to be the histological type of lung cancer most tightly related with residential radon.

journal_name

Cancer Lett

journal_title

Cancer letters

authors

Rodríguez-Martínez Á,Torres-Durán M,Barros-Dios JM,Ruano-Ravina A

doi

10.1016/j.canlet.2018.04.003

subject

Has Abstract

pub_date

2018-07-10 00:00:00

pages

57-62

eissn

0304-3835

issn

1872-7980

pii

S0304-3835(18)30264-7

journal_volume

426

pub_type

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