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Urinary excretion of N-nitrosodiethanolamine administered orally to rats.

Abstract：

:N-Nitrosodiethanolamine (NDE1A) was administered by gavage to male rats in single doses of 1000, 500 and 100 mg/kg body wt. More than 70% of a given dose was excreted unchanged in the urine, essentially within the first 24 h after exposure. This high excretion rate might explain the relatively low carcinogenic potential of NDE1A, and also offers a possible method of monitoring exposure to this compound under occupational and/or environmental conditions.

journal_name

Cancer Lett

journal_title

Cancer letters

authors

Preussmann R,Würtele G,Eisenbrand G,Spiegelhalder B

doi

10.1016/s0304-3835(78)94512-3

subject

Has Abstract

pub_date

1978-04-01 00:00:00

pages

207-9

issue

4

eissn

0304-3835

issn

1872-7980

pii

S0304-3835(78)94512-3

journal_volume

4

pub_type

杂志文章

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