Abstract：
:The results of 24 h oesophageal pH monitoring, performed in 129 infants aged 6-10 weeks, were compared to those in the same patients after shorter periods (3, 6, 9 and 12 h). In the investigated population there was no significant difference between the reflux index (percentage of time with a pH < 4.0) after 12 or 24 h. Moreover, the correlation coefficient between the reflux index after 12 and 24 h was excellent (r 0.95). However, the intra-individual difference in reflux index after 12 and 24 h was 5% in 19% of the infants, and even exceeded 10% in more than 5% of the infants, making the interpretation of the results unreliable. Even in this particular population of infants in whom a 24-h period could be divided into almost identical periods (including a feeding and a sleeping period), 24-h registrations provided the most reliable results. However, if for some reason the investigation had to be interrupted after a minimum of 12 h, the risk for erroneous interpretation of the data appeared to be acceptable. The results of this study must not be extrapolated to older children.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Vandenplas Y,Casteels A,Naert M,Derde MP,Blecker Udoi
10.1007/BF01959212subject
Has Abstractpub_date
1994-02-01 00:00:00pages
80-3issue
2eissn
0340-6199issn
1432-1076journal_volume
153pub_type
杂志文章abstract：UNLABELLED:Over the past decade, concerns about bullying and its effects on school health have grown. However, few studies in Turkey have examined the prevalence of bullying in childhood and adolescence and its association with health problems. The current study aimed to examine the prevalence and manifestation of bull...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1782-9
更新日期：2012-10-01 00:00:00
abstract：:Brain hypoxia after cardiac arrest leads to damage of the neuronal cell membrane. Citicoline is necessary for the synthesis of cell membrane. We planned to assess the neuroprotective effect of citicoline in children after cardiac arrest. This randomized controlled trial was carried out at pediatric intensive care unit...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03871-6
更新日期：2020-11-10 00:00:00
abstract：UNLABELLED:In a Swiss screening programme for detection of congenital adrenal hyperplasia (CAH), 27 of over 120,000 newborns examined from 1992 to 1994 were further studied because of persistingly high 17 alpha hydroxyprogesterone (17OHP). Out of 27, 11 were later confirmed to have CAH by specific gas chromatography of...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02282880
更新日期：1996-11-01 00:00:00
abstract：:Autoimmune hepatitis (AIH) is a member of autoimmune diseases family which can increase risk of cardiovascular morbidity and mortality. This study aimed to assess subclinical impact of AIH on global myocardial performance in affected children using Doppler tissue imaging (DTI) and to correlate it with total serum immu...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章
doi：10.1007/s00431-013-2073-9
更新日期：2013-11-01 00:00:00
abstract：:Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by mutations of one of the subunits of phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase leading to decreased or complete absence of neutrophil oxidative burst. We report the clinical and laboratory findings in tw...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-006-0211-3
更新日期：2007-02-01 00:00:00
abstract：UNLABELLED:Although a range of antiretroviral drugs are available for use in children, the appropriate paediatric regimen remains unclear. In a survey to investigate policies and practices relating to the therapeutic management of children infected by the human immunodeficiency virus (HIV), a postal questionnaire was s...
journal_title：European journal of pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s004310050045
更新日期：2000-03-01 00:00:00
abstract：:A case of subacute meningitis caused by Brucella mellitensis is described. The meningitis was refractory to an antibiotic regime. Diagnosis was established by raised antibody titres to Brucella in serum and cerebrospinal fluid (CSF) and positive bone marrow and blood cultures. While treatment with tetracycline trimeth...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00445917
更新日期：1988-11-01 00:00:00
abstract：UNLABELLED:This study aimed to determine the population pharmacokinetics of doxapram in low-birth-weight (LBW) infants. A total of 92 serum concentration measurements that were obtained from 34 Japanese neonates were analyzed using nonlinear mixed-effect modeling (NONMEM). Estimates generated by NONMEM indicated that c...
journal_title：European journal of pediatrics
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00431-014-2416-1
更新日期：2015-04-01 00:00:00
abstract：:Retrospective analysis was performed at an affiliated university children's hospital with consecutive patients receiving a venoarterial extracorporeal membrane oxygenation (VA-ECMO) for refractory cardiogenic shock from July 2007 to May 2018. Fifty-six patients underwent VA-ECMO for refractory cardiogenic shock with t...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-019-03352-5
更新日期：2019-06-01 00:00:00
abstract：:Eight patients with the syndrome of benign paroxysmal vertigo of childhood are presented. This symptom complex is characterized by attacks of vertigo in young children combined with nystagmus, ataxia and transiently decreased vestibular function, but without impaired consciousness. Diagnostic and follow-up studies rev...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01846035
更新日期：1980-08-01 00:00:00
abstract：:A male infant with transient citrullinemia is described. Initially, he was found to have hypertyrosinemia and hypermethioninemia upon routine neonatal screening for inborn errors of metabolism performed at 4 days of age and was revealed to have citrullinemia upon detailed examination of plasma amino acids. At 30 days ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00445674
更新日期：1983-10-01 00:00:00
abstract：UNLABELLED:Implementation of guidelines for group B streptococcal (GBS) prepartum screening (PS) rarely has been prospectively evaluated. To assess PS at 35-37 weeks of gestation and compare its predictive value to that of an intrapartum screening (IS) within 7 days of delivery, a surveillance cohort study was conducte...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-015-2548-y
更新日期：2015-06-01 00:00:00
abstract：UNLABELLED:Schimke immuno-osseous dysplasia is a multisystem disorder consisting of spondylo-epiphysial dysplasia, progressive renal insufficiency due to focal segmental glomerulosclerosis, and immunodeficiency. Cerebrovascular complications have only been described in five patients. Here we report a patient with promi...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050714
更新日期：1997-10-01 00:00:00
abstract：:Hypoparathyroidism is one of the recognized causes of late-onset neonatal hypocalcemia. Maternal hypercalcemic hyperparathyroidism has been shown to suppress fetal parathyroid glands, causing transient neonatal hypoparathyroidism. We report two siblings (6 years apart) with transient hypoparathyroidism presented with ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0528-6
更新日期：2008-04-01 00:00:00
abstract：:The main goal for the neonatologist is to facilitate the adaptation to extra-uterine life during initial transition, while minimizing lung injury opening and protecting the premature lung from the first breath onwards. An appropriate management from birth should lead to the achievement of an early functional residual ...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-017-2984-y
更新日期：2017-10-01 00:00:00
abstract：UNLABELLED:Monitoring fat free mass (FFM), an indicator of nutritional status and a predictor of exercise performance in children, is particularly important in patients with cystic fibrosis (CF). We assessed validity of the skinfold method for measuring FFM, and its changes with exercise training, in children with CF. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310051209
更新日期：1999-10-01 00:00:00
abstract：:Five patients, 11 months to 3 4/12 years old with severe normochromic, normocytis anemia and reticulocytopenia are reported. At the height of erythropoietic arrest when erythroid precursor cells were completely absent, undifferentiated stem cells (transitional cells), accumulated in the bone marrow. They disappeared a...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00497680
更新日期：1976-08-16 00:00:00
abstract：:When boys affected with steroid sulfatase deficiency are delivered, the lack of the enzyme in the placenta may cause birth complications. In postnatal life this gene defect gives rise to X-linked recessive ichthyosis. In a series of 25 patients birth complications were reported in 9 cases. Of these boys, 4 displayed b...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00661898
更新日期：1983-03-01 00:00:00
abstract：UNLABELLED:Over the last decade, substantial progress has been made in the field of pertussis research. This includes better understanding of virulence mechanisms and their influence on the pathogenicity of Bordetella pertussis, increased awareness of the broad spectrum of disease and more insight into the host's immun...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/pl00008429
更新日期：2001-04-01 00:00:00
abstract：UNLABELLED:Two patients are described with acute collapse caused by pericardial effusion following central venous catheterisation. Echocardiography during resuscitation allowed prompt identification and management. CONCLUSION:Pericardial effusion should be considered in any baby experiencing acute deterioration with a...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310100828
更新日期：2001-12-01 00:00:00
abstract：:The aim of this retrospective study was to describe the epidemiology and spectrum of infections of admitted pediatric refugees and asylum seekers in a tertiary referral hospital in a high-income country in Europe. We identified recent refugees and asylum seekers < 18 years of age admitted to the University Children's ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-3014-9
更新日期：2017-12-01 00:00:00
abstract：:The new coronavirus disease outbreak in 2019 (COVID-19) represents a dramatic challenge for healthcare systems worldwide. As to viral tropism, lungs are not the only COVID-19 target but also the heart may be involved in a not negligible percentage of the infected patients. Myocarditis-related cardiac dysfunction and p...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03699-0
更新日期：2020-07-01 00:00:00
abstract：:We addressed growth of biliary atresia (BA) patients living with native livers between ages 0-6 and effects of post-surgical corticosteroid treatment on growth. Growth charts of 28 BA patients born in Finland between 1987 and 2017 were retrospectively evaluated. Dosage and length of corticosteroid treatment and hydroc...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-018-3302-z
更新日期：2019-03-01 00:00:00
abstract：:So far, a recognizable pattern of clinical symptoms for child sexual abuse (CSA), especially in young male children, is lacking. To improve early recognition of CSA, we reviewed physical complaints, physical examination, and tests on sexually transmitted infections (STIs) in confirmed victims (predominantly preschool ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-2996-7
更新日期：2017-10-01 00:00:00
abstract：:GB virus C (GBV-C) is a blood-borne flavivirus. The prevalence of GBV-C viremia among healthy adults is 0.5% to 4% and, to date, no disease has been definitely associated with GBV-C infection. We conducted a cross-sectional study to evaluate GBV-C viremia prevalence in a group of 327 healthy children with normal alani...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0624-7
更新日期：2008-09-01 00:00:00
abstract：:We report on a youngster followed by his paediatrician from birth until 14 years of age for premature beats, most likely of ventricular origin. The sudden death of his sister provoked a re-assessment of his electrocardiograms (ECG), resulting in the diagnosis of Brugada syndrome and the subsequent implantation of a ca...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-006-0150-z
更新日期：2006-08-01 00:00:00
abstract：:The United Nations Convention of Children's Rights (UNCRC) introduced in 1989 has generated a global movement for the protection of children's rights and has brought about a paradigm change in how children are perceived. Pediatric healthcare professionals are interacting with children and therefore with children's rig...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-010-1205-8
更新日期：2011-01-01 00:00:00
abstract：:Cerebral blood flow velocities (CBFV) were measured by the pulsed Doppler method in 41 infants of smoking mothers and in 59 apparently healthy control infants. Although gestational age, birth weight, and systolic blood pressure were lower in infants exposed to tobacco smoke prenatally, systolic (65 +/- 11 vs. 47 +/- 1...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01956151
更新日期：1993-03-01 00:00:00
abstract：:We report a 28-day-old female infant with pertussis presenting as severe acute bronchiolitis with cyanosis. On admission, the patient's symptoms were similar to those of acute bronchiolitis. However, occasional apneic episodes with cyanosis and peripheral lymphocytosis suggested neonatal pertussis and prompted us to e...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-008-0744-8
更新日期：2009-03-01 00:00:00
abstract：UNLABELLED:A retrospective analysis of 218 bunk-bed accidents and a random sample survey with 991 family interviews were performed in order to establish guidelines for bunk-bed accident prevention. Falls from the top bed during sleep (35.1%) or while playing (34.4%) and falling off the ladder (23.2%) are the leading ca...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310051303
更新日期：2000-06-01 00:00:00
