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Skinfold measurements in children with cystic fibrosis: monitoring fat-free mass and exercise effects.

Abstract：

UNLABELLED:Monitoring fat free mass (FFM), an indicator of nutritional status and a predictor of exercise performance in children, is particularly important in patients with cystic fibrosis (CF). We assessed validity of the skinfold method for measuring FFM, and its changes with exercise training, in children with CF. A total of 14 children with moderately severe symptoms of CF (age 10-18 years) were followed longitudinally and measured three times, before (at 0 and 6 months) and after exercise training (at 12 months). Separately, single measurements were conducted in 12 children with mild symptoms of CF and in 13 healthy controls. FFM was calculated from four skinfold measurements, and compared with estimations from total body water measured with deuterium dilution. The FFM calculated from skinfolds was 1.7% (P < 0.05) and 3.3% (P < 0.005) higher than that estimated with deuterium oxide dilution in patients with CF and controls, respectively. Limits of agreement were similar in patients with moderate and mild symptoms and in controls. The measurements in patients with moderate symptoms showed similar bias and limits of agreement at 6 and 12 months as compared to 0 months. Changes in FFM measured with both methods were significantly correlated before exercise (r = 0.82, P < 0.0005), and after exercise training (r = 0. 60, P < 0.05). CONCLUSION:In children with cystic fibrosis, skinfold measurements are applicable to monitor fat free mass irrespective of clinical severity of the disease, and repeated measurements at intervals of 6 months are applicable to monitor changes in fat free mass during exercise training.

journal_name

Eur J Pediatr

journal_title

European journal of pediatrics

authors

de Meer K,Gulmans VA,Westerterp KR,Houwen RH,Berger R

doi

10.1007/s004310051209

keywords:

subject

Has Abstract

pub_date

1999-10-01 00:00:00

pages

800-6

issue

10

eissn

0340-6199

issn

1432-1076

pii

91580800.431

journal_volume

158

pub_type

杂志文章

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