The RecF pathway of homologous recombination can mediate the initiation of DNA damage-inducible replication of the Escherichia coli chromosome.

Abstract:

:DNA damage-inducible DNA replication in SOS-induced Escherichia coli cells, termed inducible stable DNA replication (iSDR), has previously been shown to require either the RecBCD or the RecE pathway of homologous recombination for initiation. Here, we demonstrate that recB recC sbcC quadruple mutant cells are capable of iSDR induction and that a mutation in the recJ gene abolishes the inducibility. These results indicate that the RecF pathway of homologous recombination can also catalyze iSDR initiation.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Asai T,Kogoma T

doi

10.1128/jb.176.22.7113-7114.1994

subject

Has Abstract

pub_date

1994-11-01 00:00:00

pages

7113-4

issue

22

eissn

0021-9193

issn

1098-5530

journal_volume

176

pub_type

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