Abstract：
:Phospholipid metabolism of 3T3 mouse fibroblasts has been studied after serum stimulation of arrested cells. The study of [32Pi] incorporation shows : a) in the case of PE and PC an early peak of incorporation in the G1 phase of the cell cycle, 6 hours after serum addition; b) in the case of PI an intense initial increasing of the incorporation which continues up to a S phase peak. The study of the disappearance of [32P] Phosphate from the different phospholipids points out: a) at the beginning of serum stimulation, an intense breakdown of PI, that continues through the G1 and S phases. Except at the onset, the breakdown of PI, is at any time exactly compensated for by synthesis : the two phenomena are closely linked; b) a synthesis of PE, from PC probably, at the G1 phase, 4 hours after the serum addition and the beginning of the chase experiment.
journal_name
Biochimiejournal_title
Biochimieauthors
Dubois C,Rampini Cdoi
10.1016/s0300-9084(79)80448-4subject
Has Abstractpub_date
1978-01-01 00:00:00pages
1307-13issue
11-12eissn
0300-9084issn
1638-6183journal_volume
60pub_type
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