Does barbiturate anesthesia modify the neuronal properties of the somatosensory thalamus? A single-unit study related to nociception in the awake-pentobarbital-treated rat.

abstract：:The objective of this study was to test the hypothesis that 4 weeks of lithium administration would be associated with changes in brain gray and white matter volumes in healthy individuals. Thirteen right-handed healthy volunteers (6 females, mean age=25.9+/-10.0 years) were studied. 3D SPGR MRIs (TR=25 ms, TE=5 ms, s...

journal_title：Neuroscience letters

authors： Monkul ES,Matsuo K,Nicoletti MA,Dierschke N,Hatch JP,Dalwani M,Brambilla P,Caetano S,Sassi RB,Mallinger AG,Soares JC

更新日期：2007-12-11 00:00:00

abstract：:A previous study suggested that adults with greater motor difficulties demonstrated less adaptation under a regular error feedback schedule (gain=1:1) but reached a similar level of adaptation compared to controls when feedback was enhanced (gain=1:2). In light of these findings, the present study examined inter-limb ...

journal_title：Neuroscience letters

authors： Bo J,Lee CM

更新日期：2017-07-27 00:00:00

abstract：AIMS:To test the hypothesis that uridine 5'-triphosphate (UTP) had a protective effect on cerebral ischemia reperfusion (IR) injury in rats. METHODS:Ischemia was induced by intraluminal suture of middle cerebral artery occlusion (MCAO). UTP solution was delivered through an indwelling tail venous catheter via microinf...

journal_title：Neuroscience letters

authors： Tian ML,Zou Z,Yuan HB,Wang CC,Zhu QF,Xu HT,Gao X,Shi XY

更新日期：2009-11-06 00:00:00

abstract：:This study examined the effects of anterior pretectal nucleus (APT) conditioning stimulation on the activity of 92 functionally identified somatosensory brainstem neurons in the trigeminal (V) subnuclei oralis, interpolaris and caudalis of anesthetized rats. Conditioning stimulation inhibited most of the nociceptive n...

journal_title：Neuroscience letters

authors： Chiang CY,Chen IC,Dostrovsky JO,Sessle BJ

更新日期：1992-01-06 00:00:00

abstract：:The combination of ethanol and cocaine is commonly abused by human addicts which has serious clinical consequences. Here, the effects of separately and concurrently administered ethanol and 'binge' cocaine on kappa opioid receptor (KOR) mRNA in the ventral tegmental area (VTA) and nucleus accumbens (NAc) of rats were ...

journal_title：Neuroscience letters

authors： Rosin A,Lindholm S,Franck J,Georgieva J

更新日期：1999-11-05 00:00:00

abstract：:Nogo-A is an inhibitor of neurite outgrowth and axonal regeneration after CNS injury. Several functional regions including Nogo-66 were identified to mediate the inhibitory effect of Nogo-A. We have reported that Nogo-66 could promote neural progenitors to differentiate into glial cells. Here we exam three other regio...

journal_title：Neuroscience letters

authors： Gao Y,Xiao Z,Chen B,Wang B,Han J,Zhao Y,Zhang J,Dai J

更新日期：2009-07-24 00:00:00

abstract：:The circadian modulation of occurrence of non-rapid-eye-movement sleep (NREM) was investigated in 37 volunteers under dim-light conditions after 24-h total sleep deprivation using a 26-h 10/20-min ultra-short sleep-wake schedule. The propensity of NREM showed rapid increase followed by gradual decrease during the subj...

journal_title：Neuroscience letters

authors： Tagaya H,Uchiyama M,Shibui K,Kim K,Suzuki H,Kamei Y,Okawa M

更新日期：2002-04-19 00:00:00

abstract：:The regulation of blood glucose level in intracerebroventricular (i.c.v.) administration with opioid alone or opioid withdrawal model was studied in ICR mice. In the first group, we found that i.c.v. administered morphine or beta-endorphin alone causes an elevation of blood glucose level. Blood glucose level induced b...

journal_title：Neuroscience letters

authors： Park SH,Sim YB,Kang YJ,Kim SM,Lee JK,Jung JS,Suh HW

更新日期：2010-06-07 00:00:00

abstract：:Decreased dopamine (DA) release in the hippocampus may be caused by dysfunctional mastication, although the mechanisms involved remain unclear. The present study examined the effects of soft- and hard-food diets on oxidative stress in the brain, and the relationship between these effects and hippocampal DA levels. The...

journal_title：Neuroscience letters

authors： Yoshino F,Yoshida A,Hori N,Ono Y,Kimoto K,Onozuka M,Lee MC

更新日期：2012-02-02 00:00:00

abstract：:Circadian firing rhythms of cultured rat suprachiasmatic nucleus were measured simultaneously from 4-8 neurons by using a multi-electrode dish and neuronal interactions were examined by a cross-correlation analysis of spontaneous action potentials. Functional connections were detected in the neuron pairs showing synch...

journal_title：Neuroscience letters

authors： Honma S,Shirakawa T,Nakamura W,Honma K

更新日期：2000-11-17 00:00:00

abstract：:Several genes expressed in the suprachiasmatic nucleus (SCN) are induced by light and are candidate links in the photic entrainment pathway of the SCN's circadian clock. Since the cAMP response element binding protein (CREB) and CRE-mediated gene transcription in the SCN appears to be crucial for light-induced phase s...

journal_title：Neuroscience letters

authors： Schwartz WJ,Aronin N,Sassone-Corsi P

更新日期：2005-09-02 00:00:00

abstract：:Because reelin and prestin genes are located close together on mouse chromosome 5, reelin homozygous mutant mice were compared with littermate controls. Experiments were designed to determine if the deletion in the reeler mouse affects the coding and/or regulatory regions for the expression of prestin, the outer hair ...

journal_title：Neuroscience letters

authors： Zheng J,Richter CP,Cheatham MA

更新日期：2003-08-14 00:00:00

abstract：:Twelve human subjects performed a reciprocal precision aiming task of varying difficulty (index of difficulty=4, 5, or 6) while vision of the ongoing movement was available either continuously or intermittently. In the intermittent conditions, vision of the moving end-effector was available at regular intervals (equal...

journal_title：Neuroscience letters

authors： Bootsma RJ,Boulard M,Fernandez L,Mottet D

更新日期：2002-11-22 00:00:00

abstract：:In non-diabetic mice, s.c. injection of formalin to the hindpaw had a biphasic effect: an immediate nociceptive response (first-phase) followed by a tonic response (second-phase). However, only the immediate nociceptive response was observed in diabetic mice. The duration of the first-phase response was significantly ...

journal_title：Neuroscience letters

authors： Kamei J,Hitosugi H,Kasuya Y

更新日期：1993-01-12 00:00:00

abstract：:Immunoelectron microscopy combined with a retrograde tracing technique was carried out to examine the synaptic interaction between neuropeptide Y (NPY)-like immunoreactive (LI) axon terminals and spinal motoneurons innervating bulbocavernosus muscles. Cell bodies and proximal dendrites of these motoneurons were freque...

journal_title：Neuroscience letters

authors： Kawano M,Sugita O,Inagaki S,Furuyama T,Takagi H

更新日期：1993-04-02 00:00:00

abstract：:The retrotrapezoid nucleus (RTN), a part of the rostral ventrolateral medulla, is involved in the control of breathing. The mechanisms by which the RTN modulate the activity of respiratory neurons during chemoreceptor stimulation are not fully understood. This electrophysiological study performed in the cat demonstrat...

journal_title：Neuroscience letters

authors： Bodineau L,Frugière A,Marlot D,Wallois F

更新日期：2000-02-18 00:00:00

abstract：:The effect of bifemelane hydrochloride (BFH) on the induction of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient global ischemia in gerbil brain was investigated by in situ hybridization using cloned cDNA probes selective for each mRNA species. Following 3.5 min of ischemia, H...

journal_title：Neuroscience letters

authors： Aoki M,Abe K,Liu XH,Lee TH,Kato H,Kogure K

更新日期：1993-05-14 00:00:00

abstract：:Neuromelanin (NM)-containing dopaminergic neurons in the substantia nigra are selectively vulnerable in Parkinson's disease (PD), suggesting the involvement of NM in the pathogenesis. NM is composed of protein, lipid, trace metals and melanin component, a mixture of eumelanin produced from dopamine (DA)-quinone and ph...

journal_title：Neuroscience letters

authors： Naoi M,Yi H,Maruyama W,Inaba K,Shamoto-Nagai M,Akao Y,Gerlach M,Riederer P

更新日期：2009-11-13 00:00:00

abstract：:The hypothesis involving glutamate in the neuropathology of schizophrenia has attracted great interest. Several studies report dysfunctions in glutamatergic systems, including alterations in kainate and N-methyl-D-aspartate (NMDA) receptors in various areas, as well as changes in the number of glutamate uptake sites. ...

journal_title：Neuroscience letters

authors： Aparicio-Legarza MI,Cutts AJ,Davis B,Reynolds GP

更新日期：1997-08-22 00:00:00

abstract：:Successful transplantations have been made of cultured explants of human fetal spinal cord into surgically created cavities in the motor cortical area of non-immunosuppressed young adult rats. The cultured cells were marked by brief incubation with Phaseolus vulgaris leucoagglutinin (PHA) just prior to transplantation...

journal_title：Neuroscience letters

authors： Kamo H,Kim SU,McGeer PL,Araki M,Tomimoto H,Kimura H

更新日期：1987-05-06 00:00:00

abstract：:Taurine increases in brain extracellular space due to glutamate agonists were studied in vivo in the rat hippocampus using a dialysis technique, both in the absence and in the presence of glutamate receptor antagonists. Extracellular taurine levels increased during perfusions of agonists, listed in descending order of...

journal_title：Neuroscience letters

authors： Menéndez N,Herreras O,Solis JM,Herranz AS,Martín del Río R

更新日期：1989-07-17 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is expressed in and defines a subset of motor neuron pools in the lumbar spinal cord of the chick embryo. The onset of CGRP expression in individual pools coincides with both the period of the initial innervation of the leg and the beginning of naturally occurring cell death in t...

journal_title：Neuroscience letters

authors： Mason IJ,Mudge AW

更新日期：1992-04-13 00:00:00

abstract：OBJECTIVES:To determine clinical characteristics and frequency of leucine-rich repeat kinase 2 gene (LRRK2) mutations in a cohort of patients with Parkinson's disease (PD) from Argentina. BACKGROUND:Variation in the LRRK2 gene represents the most common genetic determinant of PD, only few data are available from Latin...

journal_title：Neuroscience letters

authors： Gatto EM,Parisi V,Converso DP,Poderoso JJ,Carreras MC,Martí-Massó JF,Paisán-Ruiz C

更新日期：2013-03-14 00:00:00

abstract：:Accumulating evidence suggests that abnormal fatty acid composition is related to the development of Alzheimer's disease (AD). However, there is no consistency in the fatty acid profile and metabolism associated with AD pathogenesis. This study aims to define the characteristics of fatty acid composition and metabolis...

journal_title：Neuroscience letters

authors： Bai YR,Wang YY,Meng DL,Shi ZL,Song XF,Yang ZZ,Zhang W,Yang L,Shi RL

更新日期：2020-11-01 00:00:00

abstract：:Selective loss of central dopaminergic neurons in vitro and in vivo can be initiated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) through its metabolite phenylpyridium ion (MPP+). Such MPTP-mediated cytotoxicity can be blocked by (-)-Deprenyl, a monoamine oxidase (MAO)-B inhibitor, but the exact mechanisms o...

journal_title：Neuroscience letters

authors： Le W,Jankovic J,Xie W,Kong R,Appel SH

更新日期：1997-03-21 00:00:00

abstract：:Changes in the intracellular Ca2+ concentration ([Ca2+]i) induced by ischemia in vitro (oxygen-glucose deprivation) were continuously recorded using fura-2-loaded hippocampal slices under normal (pH 7.4), acidotic (pH 6.8) and alkalotic (pH 7.8) conditions. Oxygen-glucose deprivation induced an initial slow and a subs...

journal_title：Neuroscience letters

authors： Ebine Y,Fujiwara N,Shimoji K

更新日期：1994-02-28 00:00:00

abstract：:Chronic morphine administration induces neural plasticity followed by withdraw. And clinic observation indicates that obvious cognitive deficits are found during withdrawal. However, current neural substrates that regulate dysfunction in withdrawal are unknown. In our studies, chronic morphine administration was used ...

journal_title：Neuroscience letters

authors： Niu H,Zhang G,Li H,Zhang Q,Li T,Ding S,Wang L,Zhang Z,Qiao Y,Hu M

更新日期：2017-02-15 00:00:00

abstract：:Emotional processing in coma remains an open question. Skin conductance responses to emotional and neutral auditory stimuli were recorded in 13 low-responsive patients (12 of whom were in coma). A differential response between emotional and neutral stimuli was found, which significantly correlated with the Glasgow Com...

journal_title：Neuroscience letters

authors： Daltrozzo J,Wioland N,Mutschler V,Lutun P,Calon B,Meyer A,Jaeger A,Pottecher T,Kotchoubey B

更新日期：2010-05-07 00:00:00

abstract：:Cytoplasmic acidification in taste receptor cells is thought to be involved, at least in part, in acid taste transduction. Since in taste buds about 20% of the receptor cells are electrically coupled, we have tested whether reduction in intracellular pH affects these lateral synaptic interactions. By applying the patc...

journal_title：Neuroscience letters

authors： Bigiani A,Roper SD

更新日期：1994-08-01 00:00:00

abstract：:The neuron-specific phosphoprotein B-50 (GAP-43) is associated with neuritogenesis during development and regeneration. We monitored B-50 in cultured spinal neurons (fetal rat) with an enzyme-linked immunoadsorbent assay. B-50 levels increased from 24 to 72 h, then decreased. Other cultures, fixed at 24 h intervals an...

journal_title：Neuroscience letters

authors： van der Neut R,Oestreicher AB,Gispen WH,Bär PR

更新日期：1990-02-05 00:00:00