Abstract:
:In the frog Xenopus, the somatic-type 5S ribosomal RNA genes are active in all cells; the oocyte-type 5S genes are active in oocytes but not in somatic cells. A new method of native gel electrophoresis resolves the two types of 5S RNA which are of the same length but different sequence. When somatic nuclei were injected into oocytes, their inactive oocyte-type 5S genes often remained inactive, and had thus conserved their developmentally regulated condition. Other conditions, which include treatment with 0.35 M NaCl, reactivated the genes.
journal_name
Naturejournal_title
Natureauthors
Korn LJ,Gurdon JBdoi
10.1038/289461a0subject
Has Abstractpub_date
1981-02-05 00:00:00pages
461-5issue
5797eissn
0028-0836issn
1476-4687journal_volume
289pub_type
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