Abstract:
:We have obtained evidence that poliovirus and other picornavirus particles are specifically modified by having myristic acid covalently bound to a capsid protein. The electron density map of poliovirus confirms the position of the myristate molecule and defines its location in the virus particle. Analogies with other myristylated proteins suggest that the myristate moiety in picornaviruses may be involved in capsid assembly or in the entry of virus into cells.
journal_name
Naturejournal_title
Natureauthors
Chow M,Newman JF,Filman D,Hogle JM,Rowlands DJ,Brown Fdoi
10.1038/327482a0subject
Has Abstractpub_date
1987-06-11 00:00:00pages
482-6issue
6122eissn
0028-0836issn
1476-4687journal_volume
327pub_type
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