Sex, constancy, and skin bacteria.

abstract：:CCN2 plays an important role in the pathogenesis of hypertrophic scars (HTSs). Although CCN2 is involved in many fibroproliferative events, the CCN2 induction signaling pathway in HTSs is yet to be elucidated. Here, we first investigated the effect of the mitogen-activated protein kinases (MAPKs) on CCN2-induced α-smo...

journal_title：Archives of dermatological research

authors： Hu X,Wang H,Liu J,Fang X,Tao K,Wang Y,Li N,Shi J,Wang Y,Ji P,Cai W,Bai X,Zhu X,Han J,Hu D

更新日期：2013-07-01 00:00:00

abstract：:The pathogenicity of Mycobacterium ulcerans (Buruli ulcer) is closely associated with the secretion of exotoxin mycolactone. The cytotoxicity of mycolactone has been linked to its apoptogenic activity. We explored if low mycolactone concentrations, which are not able to induce apoptosis, can influence other essential ...

journal_title：Archives of dermatological research

authors： Graziola F,Colombo E,Tiberio R,Leigheb G,Bozzo C

更新日期：2017-04-01 00:00:00

abstract：:Antihistamines are the first-line treatment for chronic urticaria (CU). However, some CU patients are relatively refractory to antihistamines. The mechanism underlying the interindividual variation is still unknown. The α-chain of the high-affinity IgE receptor is crucial to the IgE-mediated allergic response. The pre...

journal_title：Archives of dermatological research

authors： Guo A,Zhu W,Zhang C,Wen S,Chen X,Chen M,Zhang J,Su J,Chen W,Zhao Y,Yan S,He Y,Liu Z,Zhou H,Chen X,Li J

更新日期：2015-03-01 00:00:00

abstract：:It has been reported that artificial restoration of barrier function by a water vapor-impermeable membrane after tape stripping induces barrier abrogation in hairless mice, impeding rather than enhancing barrier recovery. To address this issue, we examined the morphologic changes in the epidermis after tape stripping ...

journal_title：Archives of dermatological research

authors： Jiang S,Koo SW,Lee SH

更新日期：1998-03-01 00:00:00

abstract：:The distribution of several markers of keratinocyte differentiation was studied in normal epidermis, basal cell carcinomas (BCCs), and squamous cell carcinomas (SCCs) using the immunoperoxidase technique on frozen sections of punch biopsy specimens. As markers a panel of chain-specific monoclonal antibodies (MoAbs) di...

journal_title：Archives of dermatological research

authors： Lavrijsen AP,Tieben LM,Ponec M,van der Schroeff JG,van Muijen GN

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Data on how patients with a history of skin cancer apply sunscreen are lacking. OBJECTIVE:To characterize (1) gender differences in sunscreen application technique (quantity used, anatomic site coverage, and time allocated) and (2) differences in sunscreen application to unaffected skin versus previous skin...

journal_title：Archives of dermatological research

authors： Dang J,Reserva J,Tung-Hahn E,Vasicek B,Krol C,Adams W,Tung R,Alam M

更新日期：2020-12-01 00:00:00

abstract：:To investigate the turnover of complete junctional membrane areas ("domain turnover"), psoriatic epidermis, keratoacanthoma, and squamous cell carcinoma were studied with an electron microscope and compared with the normal epidermis. Three types of domain turnover of junctions were observed. First, the uptake of intac...

journal_title：Archives of dermatological research

authors： Mahrle G

更新日期：1982-01-01 00:00:00

abstract：:In a previous study, impedance measurements and phoreographic response were shown to quantify significant differences between involved and non-involved skin in psoriasis. The same techniques were used to objectivate the evolution on skin condition on patients treated with dioxyanthranol, difluprednate, and photochemot...

journal_title：Archives of dermatological research

authors： Cambrai M,Clar EJ,Grosshans E,Altermatt C

更新日期：1979-03-31 00:00:00

abstract：:The pathogenetic mechanisms in vitiligo have not been completely clarified. One of the major hypotheses in the pathogenesis of vitiligo is the oxidative stress hypothesis. The active or stable phase of vitiligo is defined on the basis of the progression or appearance of new lesions in the last 3 months and the absence...

journal_title：Archives of dermatological research

authors： Ines D,Sonia B,Riadh BM,Amel el G,Slaheddine M,Hamida T,Hamadi A,Basma H

更新日期：2006-09-01 00:00:00

abstract：:Stress is a well-known triggering factor along with genetic predisposition on the onset and during the course of psoriasis by altering the cellular constituents of the immune system. In the skin, there is a local hypothalamic-pituitary-adrenal (HPA) axis which is the equivalent of the central HPA axis. Corticotropin-r...

journal_title：Archives of dermatological research

authors： Cemil BC,Canpolat F,Yilmazer D,Eskioğlu F,Alper M

更新日期：2012-03-01 00:00:00

abstract：:Recent evidence indicates that the biologically active metabolite of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 [1 alpha,25(OH)2D3], has an effect on the regulation of the immune response. We investigated whether topical treatment of mice with 1 alpha,25(OH)2D3 influences the contact hypersensitivity (CHS) response to...

journal_title：Archives of dermatological research

authors： Tani M,Murata Y,Harada S,Takashima T,Horikawa T

更新日期：1989-01-01 00:00:00

abstract：:In preparations of papillary dermis taken from clinically normal skin of patients with dermatitis herpetiformis (DH), the disappearance of granular IgA deposits induced by peptic digestion was partial at pH 4.5 and total at pH 4.1, as visualized by immunofluorescence microscopy. In a model system in which human monome...

journal_title：Archives of dermatological research

authors： Egelrud T,Bäck O

更新日期：1985-01-01 00:00:00

abstract：:Pathological alterations of capillaries, accelerated epidermopoesis, increased rate and extent of metabolism in the psoriatic lesion and first manifestation of psoriasis rarely in the first 20 years of life made us decide to investigate the human growth hormone (STH) in blood serum. In 70 patients suffering from psori...

journal_title：Archives of dermatological research

authors： Weber G,Neidhardt M,Schmidt A,Geiger A

更新日期：1981-01-01 00:00:00

abstract：:Epstein-Barr virus (EBV) can infect epithelial cells as well as B lymphocytes. Infection of the male and female genital tracts has recently been demonstrated, and it has been suggested that the virus may be sexually transmissible. In our study we investigated whether EBV can be found in the anal region of sexually act...

journal_title：Archives of dermatological research

authors： Näher H,Lenhard B,Wilms J,Nickel P

更新日期：1995-01-01 00:00:00

abstract：:It has been suggested that free fatty acids (FFA) such as palmitate, which are secreted from enlarged adipocytes in the subcutaneous fat of obese subjects, serve as a link between obesity and altered skin functions. Cyclooxygenease-2 (COX-2) and prostanoids participate in the induction of impaired dermal function. In ...

journal_title：Archives of dermatological research

authors： Oh E,Yun M,Kim SK,Seo G,Bae JS,Joo K,Chae GT,Lee SB

更新日期：2014-05-01 00:00:00

abstract：:Mite antigens play important roles in the pathogenesis of atopic dermatitis (AD). We recently developed a novel air cleaner (KC-850U) using charged plasma cluster ions to eliminate a variety of allergens from house environments. The present work demonstrates the ability of KC-850U to decrease the symptoms of AD induce...

journal_title：Archives of dermatological research

authors： Hiramoto K,Orita K,Yamate Y,Sato EF,Okano H,Nishikawa K,Inoue M

更新日期：2011-07-01 00:00:00

abstract：:Topical vitamin D3 has relatively recently been introduced for the treatment of psoriasis. Synthetic vitamin D3 analogues with a high potential for inducing differentiation of cells, but with a low hypercalcemic effect have recently been developed. One such synthetic analogue of 1,25-dihydroxyvitamin D3 (calcitriol), ...

journal_title：Archives of dermatological research

authors： Komine M,Watabe Y,Shimaoka S,Sato F,Kake K,Nishina H,Ohtsuki M,Nakagawa H,Tamaki K

更新日期：1999-09-01 00:00:00

abstract：:Despite the fact that polymorphous light eruption (PLE) is the most common photodermatosis, affecting 15% of healthy people in the UK, its pathogeny remains unclear. The condition is more frequent in females and begins often in young adults and in mid-adult life. The mechanism of PLE is under active research as shown ...

journal_title：Archives of dermatological research

authors： Aubin F

更新日期：2004-10-01 00:00:00

abstract：:All-trans retinoic acid (ATRA) is known to have beneficial effects on skin. It has been used extensively for the treatment of photodamaged skin. To assess the effects of all-trans retinoic acid on the dermis, specifically its effect on hyaluronate (hyaluronic acid, HA) synthesis and inhibition, tissue-engineered human...

journal_title：Archives of dermatological research

authors： Deshpande M,Papp S,Schaffer L,Pouyani T

更新日期：2014-09-01 00:00:00

abstract：:This study was designed in order to prove on a large-scale basis the efficacy of oral photochemotherapy (PUVA) in the prevention of polymorphous light eruption (PLE), to work out indication criteria for PUVA treatment of this disease, and to establish a simple method based on anamnestic data to differentiate UVA from ...

journal_title：Archives of dermatological research

authors： Gschnait F,Schwarz T,Ladich I

更新日期：1983-01-01 00:00:00

abstract：:The histological and ultrastructural effects following 3 weeks' topical treatment with two agents (all-trans retinoic acid and a new synthetic retinoid-like substance, CD271) were evaluated on the epidermis and the epithelial wall of the pseudocomedones in rhino mouse skin. The comedolytic effects of these drugs were ...

journal_title：Archives of dermatological research

authors： Bernerd F,Ortonne JP,Bouclier M,Chatelus A,Hensby C

更新日期：1991-01-01 00:00:00

abstract：:In human skin, epidermal differentiation occurs in two ways: normal differentiation, characterized by keratin 10 expression, and alternative differentiation. Alternative differentiation can be hyperproliferation-associated differentiation (expression of keratin 16) or the reinduction of an embryonic type of differenti...

journal_title：Archives of dermatological research

authors： van Rossum MM,Mommers JM,van de Kerkhof PC,van Erp PE

更新日期：2000-01-01 00:00:00

abstract：:Leprosy is a curable disease with well-defined etiology, but lacks better diagnostic tools, preventive and therapeutic strategies. The continued application of the Ridley-Jopling clinical classification that recognizes the natural diversity of the immune response has provided the basis for understanding leprosy, and t...

journal_title：Archives of dermatological research

authors： Goulart IM,Goulart LR

更新日期：2008-07-01 00:00:00

abstract：:Flushing in rosacea has been investigated by means of (a) pharmacological inhibition of some possible chemical mediators and (b) titration of bradykinin as a possible effector directly in the blood. Clonidine-inhibited flushing was seen in all patients (mean 45%), other drugs had poorer results. Bradykinin increased i...

journal_title：Archives of dermatological research

authors： Guarrera M,Parodi A,Cipriani C,Divano C,Rebora A

更新日期：1982-01-01 00:00:00

abstract：:Metalloproteinase-mediated proteolysis plays an important role during all stages of wound repair. In acute murine wounds, murine collagenase, matrix metalloproteinase (MMP)-9, stromelysin-1, stromelysin-2 and tissue inhibitor of metalloproteinase (TIMP)-1 are strongly induced within 24 h after wounding. At the time of...

journal_title：Archives of dermatological research

authors： Madlener M

更新日期：1998-07-01 00:00:00

abstract：:The aim of the present study was to investigate the influence of three different retinoids, isotretinoin, etretinate and acitretin, on the mitogenic response of peripheral blood mononuclear cells (PBMCs) to PHA and PMA in vitro. All three retinoids at high concentrations (10(-4)M) significantly inhibited the mitogenic...

journal_title：Archives of dermatological research

authors： Chaidaroglou A,Degiannis D,Koniavitou K,Georgiou S,Tsambaos D

更新日期：1998-04-01 00:00:00

abstract：:Plectin, a widespread cytoskeletal linker protein, is prominently expressed in basal keratinocytes of the epidermis. HD1, originally identified as a hemidesmosomal protein, has been suggested to be an isoform of or closely related to plectin, but the exact relationship between these proteins is unknown. Plectin has re...

journal_title：Archives of dermatological research

authors： Shimizu H,Masunaga T,Kurihara Y,Owaribe K,Wiche G,Pulkkinen L,Uitto J,Nishikawa T

更新日期：1999-10-01 00:00:00

abstract：:Epidermolytic hyperkeratosis (EH) is a genetic disorder of keratins associated with epidermal differentiation. Affected individuals carry gene mutations for conserved sequences of keratins K1 or K10. The structural alterations of tonofilaments in EH seem to be a direct consequence of the keratin gene mutations. EH epi...

journal_title：Archives of dermatological research

authors： Ishida-Yamamoto A,Iizuka H,Manabe M,O'Guin WM,Hohl D,Kartasova T,Kuroki T,Roop DR,Eady RA

更新日期：1995-01-01 00:00:00

abstract：:Thrombin has recently been shown not only to exert procoagulant activities, but also to induce mitogenic responses of different cell types involved in wound healing via binding to and cleavage of the thrombin receptor. In order to further explore these aspects of thrombin function, human keratinocytes (HaCaT cell line...

journal_title：Archives of dermatological research

authors： Algermissen B,Sitzmann J,Nürnberg W,Laubscher JC,Henz BM,Bauer F

更新日期：2000-10-01 00:00:00

abstract：:T Cells from 14 patients in the active stage of bullous pemphigoid and 10 patients in the inactive stage of the disease were studied with Leu-1, Leu-2, and Leu-3 monoclonal antibodies. The proportions of total T cells and T cells expressing either helper or suppressor phenotype in the peripheral blood of patients were...

journal_title：Archives of dermatological research

authors： Ahmed AR

更新日期：1985-01-01 00:00:00