Endotoxaemia and complement activation in acute pancreatitis in man.

abstract：BACKGROUND:The indications for intestinal transplantation (ITx) are still debated. Knowing survival rates and causes of death on home parenteral nutrition (HPN) will improve decisions. METHODS:A prospective 5-year study compared 389 non-candidates (no indication, no contraindication) and 156 candidates (indication, no...

journal_title：Gut

authors： Pironi L,Joly F,Forbes A,Colomb V,Lyszkowska M,Baxter J,Gabe S,Hébuterne X,Gambarara M,Gottrand F,Cuerda C,Thul P,Messing B,Goulet O,Staun M,Van Gossum A,Home Artificial Nutrition & Chronic Intestinal Failure Working Grou

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Micrometastases within bone marrow have been shown to indicate a poor prognosis in patients with epithelial tumours. However, the degree to which micrometastases represent true residual disease or cell shedding and metastatic potential, is unclear. AIM:To explore whether micrometastases represent residual d...

journal_title：Gut

authors： O'Sullivan GC,Collins JK,Kelly J,Morgan J,Madden M,Shanahan F

更新日期：1997-04-01 00:00:00

abstract：:The present study was undertaken to investigate the possibility that central nervous system monoaminergic pathways may play a role in the control of gastric acid and gastrin secretion in man. Submaximal pentagastrin stimulated (0.25 micrograms/kg/h) gastric acid secretion, as well as basal gastrin concentrations were ...

journal_title：Gut

authors： Caldara R,Barbieri C,Piepoli V,Borzio M,Masci E

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Intrasphincteric injection of botulinum toxin (Botx) has been proposed as treatment for oesophageal achalasia. However, the predictors of response and optimal dose remain unclear. AIMS:To compare the effect of different doses of Botx and to identify predictors of response. PATIENTS/METHODS:A total of 118 a...

journal_title：Gut

authors： Annese V,Bassotti G,Coccia G,Dinelli M,D'Onofrio V,Gatto G,Leandro G,Repici A,Testoni PA,Andriulli A

更新日期：2000-05-01 00:00:00

abstract：:Introduction of a radioactive gastrointestinal marker (51CrCl3) into a combined study (75SeHCAT + 58CoB12) of ileal function by whole body counting has been undertaken. The technique was assessed in 23 subjects (15 patients with inflammatory bowel disease, six on non-steroidal anti-inflammatory drugs for rheumatoid ar...

journal_title：Gut

authors： Smith T,Bjarnason I

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:There is a widespread notion that obesity leads to gastro-oesophageal reflux but scientific evidence of an association is limited and inconsistent. AIMS:To estimate the strength of the association between body mass and reflux symptoms, we performed a population based cross sectional interview study. SUBJEC...

journal_title：Gut

authors： Lagergren J,Bergström R,Nyrén O

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Tumour vascularisation is a determinant of the development of metastases. AIMS:To measure blood flow in normal stomach and gastric adenocarcinomas by laser Doppler flowmetry and correlate blood flow with vascularisation after immunohistochemical staining of resected specimens for CD31 and von Willebrand fac...

journal_title：Gut

authors： Schilling MK,Redaelli C,Friess H,Blum B,Signer C,Maurer CA,Büchler MW

更新日期：1999-09-01 00:00:00

abstract：:With oral and intravenous doses of metoclopramide there was no constant effect on the gastric emptying of test meals of glucose or sodium citrate, nor was secretion of acid by the stomach in response to test meals of glucose or sodium citrate affected. Apomorphine, in subnauseous doses (0.25 mg intravenously) slowed t...

journal_title：Gut

authors： Ramsbottom N,Hunt JN

更新日期：1970-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Fatigue is a frequent and disabling symptom reported by patients with chronic hepatitis C (CHC). Its mechanism is poorly understood. Recent attention has focused on the role of leptin and energy expenditure in CHC. Our aims were to analyse fatigue in CHC and to determine its relationship with diseas...

journal_title：Gut

authors： Piche T,Gelsi E,Schneider SM,Hébuterne X,Giudicelli J,Ferrua B,Laffont C,Benzaken S,Hastier P,Montoya ML,Longo F,Rampal P,Tran A

更新日期：2002-09-01 00:00:00

abstract：:Aspirin is generally regarded as a cause of gastric ulcer but the role of non-steroidal anti-inflammatory agents and paracetamol in the aetiology of peptic ulcer is unclear. To investigate this we conducted a case control study of 180 matched pairs of peptic ulcer patients and controls obtained from surgical and derma...

journal_title：Gut

authors： Duggan JM,Dobson AJ,Johnson H,Fahey P

更新日期：1986-08-01 00:00:00

abstract：:Previous studies have shown that ileal infusion of partially digested triglyceride inhibits jejunal motility. The partial digest used in those studies contained a mixture of glycerol, free fatty acid, mono-, di-, and triglycerides. In Part I of the present study we have separately infused emulsions containing either g...

journal_title：Gut

authors： Spiller RC,Trotman IF,Adrian TE,Bloom SR,Misiewicz JJ,Silk DB

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVES:Recent studies using the lactulose hydrogen breath test (LHBT) suggest most patients with irritable bowel syndrome (IBS) have small intestinal bacterial overgrowth (SIBO). However, the validity of the LHBT has been questioned, particularly as this test could reflect changes in oro-caecal transit. Therefore, ...

journal_title：Gut

authors： Yu D,Cheeseman F,Vanner S

更新日期：2011-03-01 00:00:00

abstract：:Chronic alcohol consumption induces cytochrome P450IIE1, enabling habitual abusers to consume far greater quantities of alcohol than normal subjects. This pathway of metabolism leads to the production of free radical species, which cause tissue damage through peroxidation of cell membranes. Groups of Wistar rats of eq...

journal_title：Gut

authors： Teare JP,Greenfield SM,Watson D,Punchard NA,Miller N,Rice-Evans CA,Thompson RP

更新日期：1994-11-01 00:00:00

abstract：:It has been suggested, on the basis of impaired granulocyte migration to skin windows, that there is a fundamental granulocyte defect in Crohn's disease. In vitro tests of granulocyte function have, however, failed to confirm this. We have studied granulocyte migration to inflamed bowel in Crohn's disease using a new ...

journal_title：Gut

authors： Saverymuttu SH,Peters AM,Lavender JP,Chadwick VS,Hodgson HJ

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Eradication of Barrett's mucosa by thermal or photoablation combined with high doses of proton pump inhibitors is a potentially attractive strategy in the management of this preneoplastic condition. However, major concerns of this method are the persistence of residual metaplastic glands beneath the new squa...

journal_title：Gut

authors： Van Laethem JL,Peny MO,Salmon I,Cremer M,Devière J

更新日期：2000-04-01 00:00:00

abstract：:Completeness of vagotomy has been assessed by use of the electrical stimulation test and the insulin test in 50 patients suffering from chronic duodenal ulceration. A positive result from either was taken as evidence of incomplete vagotomy. The electrical stimulation test provided such evidence more often than the ins...

journal_title：Gut

authors： Hollanders D

更新日期：1971-08-01 00:00:00

abstract：:The effects of intravenous N-acetylcysteine on hepatic and systemic haemodynamics were investigated in 11 patients with stable cirrhosis (eight alcohol; two primary biliary cirrhosis; one cryptogenic). N-acetylcysteine administration had no effect on the mean heart rate or mean arterial blood pressure despite a signif...

journal_title：Gut

authors： Jones AL,Bangash IH,Bouchier IA,Hayes PC

更新日期：1994-09-01 00:00:00

abstract：:The response of lymphocytes from peripheral blood and mesenteric lymph nodes to stimulation with phytohaemagglutinin in vitro has been studied in eight patients suffering from active Crohn's disease. Patients with Crohn's disease exhibited reduced responses when compared with similar studies performed in control subje...

journal_title：Gut

authors： Guillou PJ,Brennan TG,Giles GR

更新日期：1973-01-01 00:00:00

abstract：:Epithelial cells shed from the intestinal villus in starved rats were trapped in mucus which the goblet cells were stimulated to secrete; the number of trapped cells per villus was counted in whole mounts of fixed Feulgen-stained specimens from three sites in the small intestine. Increase in the interval between stimu...

journal_title：Gut

authors： Clarke RM

更新日期：1970-12-01 00:00:00

abstract：:We report the occurrence of achalasia and diffuse oesophageal spasm in brother and sister. The familial occurrence of these unusual disorders is consistent with the possibility that they share a common aetiology and indicates the potential importance of genetic predisposition. ...

journal_title：Gut

authors： Kaye MD,Demeules JE

更新日期：1979-09-01 00:00:00

abstract：OBJECTIVE:Therapeutic strategies silencing and reducing the hepatitis B virus (HBV) reservoir, the covalently closed circular DNA (cccDNA), have the potential to cure chronic HBV infection. We aimed to investigate the impact of small interferring RNA (siRNA) targeting all HBV transcripts or pegylated interferon-α (peg-...

journal_title：Gut

authors： Allweiss L,Giersch K,Pirosu A,Volz T,Muench RC,Beran RK,Urban S,Javanbakht H,Fletcher SP,Lütgehetmann M,Dandri M

更新日期：2021-01-28 00:00:00

abstract：:Multinucleated giant cells are an important feature of the granulomatous reaction in Crohn's disease (CD) but their cellular origin is poorly understood. The aim of this study was to discover if intestinal macrophages are capable of generating multinucleated giant cells in vitro in response to cytokine stimulation. Hu...

journal_title：Gut

authors： Fais S,Pallone F

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Helicobacter pylori (H pylori) infection is a major risk factor in the development of distal gastric adenocarcinoma. Development of the invasive phenotype is associated with the phenomenon of epithelial:mesenchymal transition (EMT). Soluble heparin-binding epidermal growth factor (HB-EGF) has been i...

journal_title：Gut

authors： Yin Y,Grabowska AM,Clarke PA,Whelband E,Robinson K,Argent RH,Tobias A,Kumari R,Atherton JC,Watson SA

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:Diverticulitis is a common disease with a substantial clinical and economic burden. Besides dietary fibre, the role of other foods in the prevention of diverticulitis is underexplored. DESIGN:We prospectively examined the association between consumption of meat (total red meat, red unprocessed meat, red proc...

journal_title：Gut

authors： Cao Y,Strate LL,Keeley BR,Tam I,Wu K,Giovannucci EL,Chan AT

更新日期：2018-03-01 00:00:00

abstract：:Traditional Chinese herbal remedies are widely available in the United Kingdom for the treatment of chronic skin disorders. Their benefits are considerable, but their use is completely unregulated. Two patients are described here who suffered an acute hepatitic illness related to taking traditional Chinese herbs. Both...

journal_title：Gut

authors： Kane JA,Kane SP,Jain S

更新日期：1995-01-01 00:00:00

abstract：:To investigate the basis of subclinical alveolitis in patients with primary biliary cirrhosis, 10 primary biliary cirrhosis patients were studied by bronchoalveolar lavage. Both bronchoalveolar lavage lymphoid and non-lymphoid cell populations were analysed using immunocytological methods to determine their proportion...

journal_title：Gut

authors： Spiteri MA,Johnson M,Epstein O,Sherlock S,Clarke SW,Poulter LW

更新日期：1990-02-01 00:00:00

abstract：:Computed tomography detected the presence of dilated ducts in 15 of 18 cases with extrahepatic obstructive jaundice and demonstrated the obstructing lesion in 18 out of 25. The cause of the obstruction was detected in the absence of duct dilatation, and calculi which were radiolucent on conventional radiographs were d...

journal_title：Gut

authors： Morris A,Fawcitt RA,Wood R,Forbes WS,Isherwood I,Marsh MN

更新日期：1978-08-01 00:00:00

abstract：:T-lymphocytic infiltration of the exocrine pancreas and liver in patients with chronic pancreatitis has suggested that cell mediated immune mechanisms may play a part in the pathogenesis of this disease. As expression of major histocompatibility (MHC) antigens is a prerequisite for organ specific autoimmunity, the exp...

journal_title：Gut

authors： Jalleh RP,Gilbertson JA,Williamson RC,Slater SD,Foster CS

更新日期：1993-10-01 00:00:00

abstract：:The distribution of mucosal PGE2-like activity was determined by bioassay technique in the body and antrum of the stomach and in the duodenum of healthy subjects and duodenal ulcer patients before and after administration of aspirin, paracetamol, or histamine. In healthy subjects, the oxyntic, antral and duodenal muco...

journal_title：Gut

authors： Konturek SJ,Obtulowicz W,Sito E,Oleksy J,Wilkon S,Kiec-Dembinska A

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:During development, the homeobox gene Cdx2 exerts a homeotic function, providing the positional information necessary for correct specification of the midgut endoderm. This is illustrated by the non-neoplastic gastric-type heteroplasias present at birth in the pericaecal region of Cdx2(+/-) mice. Furthermore...

journal_title：Gut

authors： Bonhomme C,Duluc I,Martin E,Chawengsaksophak K,Chenard MP,Kedinger M,Beck F,Freund JN,Domon-Dell C

更新日期：2003-10-01 00:00:00