Abstract:
:During the infection of mice with Listeria monocytogenes, there is a profound depletion of T (Thy-1+ Ig-) lymphocytes between days 1 and 4, followed by an increase in T cells to three times normal levels by day 9. The recovery of T cell numbers required cell proliferation, being sensitive to vinblastin and cyclophosphamide. Adult thymectomy 6 months before infection had no effect on recovery. The repopulating cells were no more sensitive than normal T cells to hydrocortisone. B lymphocytes (Ig+ cells) and null (Thy-1-Ig-) cells increased from day 1 after the injection of either live or (in contrast to T cells) killed Listeria organisms. Their increase was inhibited by vinblastin and cyclophosphamide. Despite T cell depletion, no depression of the antibody response to the T-dependent antigen, sheep erythrocytes, occurred during infection or when spleen cells were adoptively transferred from infected mice to irradiated recipients.
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Chan YY,Cheers Cdoi
10.1128/IAI.38.2.694-698.1982subject
Has Abstractpub_date
1982-11-01 00:00:00pages
694-8issue
2eissn
0019-9567issn
1098-5522journal_volume
38pub_type
杂志文章abstract::Tuberculosis remains a leading killer worldwide, and new approaches for its treatment and prevention are urgently needed. This effort will benefit greatly from a better understanding of gene regulation in Mycobacterium tuberculosis, particularly with respect to this pathogen's response to its host environment. We exam...
journal_title:Infection and immunity
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doi:10.1128/iai.70.3.1518-1529.2002
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journal_title:Infection and immunity
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.43.2.531-535.1984
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journal_title:Infection and immunity
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journal_title:Infection and immunity
pub_type: 杂志文章
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journal_title:Infection and immunity
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doi:10.1128/IAI.8.2.215-221.1973
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.35.2.666-673.1982
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journal_title:Infection and immunity
pub_type: 杂志文章
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.40.2.759-765.1983
更新日期:1983-05-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.61.9.3724-3729.1993
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.60.5.1894-1901.1992
更新日期:1992-05-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.63.2.456-466.1995
更新日期:1995-02-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.65.11.4606-4614.1997
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.19.2.711-719.1978
更新日期:1978-02-01 00:00:00
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journal_title:Infection and immunity
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doi:10.1128/IAI.62.4.1150-1155.1994
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.10.5.1003-1009.1974
更新日期:1974-11-01 00:00:00
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journal_title:Infection and immunity
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doi:10.1128/IAI.12.1.119-127.1975
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journal_title:Infection and immunity
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doi:10.1128/IAI.21.1.333-336.1978
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01518-08
更新日期:2009-04-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
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更新日期:1989-02-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.37.3.1112-1118.1982
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.61.4.1385-1394.1993
更新日期:1993-04-01 00:00:00
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journal_title:Infection and immunity
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doi:10.1128/IAI.24.3.869-878.1979
更新日期:1979-06-01 00:00:00
abstract::A peptidoglycan layer of Treponema pallidum kazan was isolated by solubilization of whole cells with 1% warm sodium dodecyl sulfate and subsequent digestion of an insoluble residue with proteases. Electron microscopy revealed that the peptidoglycan was isolated as a single-layered sacculus of less than 5 nm in thickne...
journal_title:Infection and immunity
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doi:10.1128/IAI.31.2.767-774.1981
更新日期:1981-02-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.55.12.2967-2976.1987
更新日期:1987-12-01 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01322-15
更新日期:2016-08-19 00:00:00
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journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.64.12.5373-5383.1996
更新日期:1996-12-01 00:00:00