HLA and nasopharyngeal carcinoma in Chinese--a further study.

abstract：:Ninety-seven Japanese patients with so-called primary non-Hodgkin's lymphoma of the central nervous system (CNS-NHL), unrelated to the acquired immunodeficiency syndrome (AIDS) or organ transplantation, were reviewed. The patients' ages ranged from 1 to 87 years (median: 58 years) with a male to female ratio of 1.77:1...

journal_title：International journal of cancer

authors： Aozasa K,Ohsawa M,Yamabe H,Shima N,Kirimoto K,Yamane T,Tsujimoto M,Kobayashi Y,Kurata A,Osada H

更新日期：1990-04-15 00:00:00

abstract：:A new cell line (K-LL-3) with exceptional characteristics was derived from a bone-marrow aspirate from a patient with poorly differentiated lymphoblastic lymphoma. The cell line was established and the cells maintained on agar feeders for over 1 year. The morphology and cytochemical staining of the primary tumor and t...

journal_title：International journal of cancer

authors： Smith SD,Rosen D

更新日期：1979-04-15 00:00:00

abstract：:Low levels of anti-viral activity, mainly interferon alpha/beta (IFN-alpha/beta), are regularly found in lymphoid tissues of BALB/c mice infected with the C3H strain of mammary tumor virus. At the time of tumor development, significant amounts of anti-viral activity were detected in homogenates of spleen and mammary t...

journal_title：International journal of cancer

authors： Basolo F,Fontanini G,Serra C,Dolei A,Proietti E,Belardelli F,Conaldi PG,Bistocchi M,Squartini F,Toniolo A

更新日期：1992-07-30 00:00:00

abstract：:Activity of Janus kinase 2 (JAK2) in the JAK2/STAT5 signaling pathway is critically controlled by suppressor of cytokine signaling-1 (SOCS-1). We have previously shown that SOCS-1 is biallelically mutated in the primary mediastinal B-cell lymphoma (PMBL) cell line MedB-1, resulting in impaired JAK2 degradation and sus...

journal_title：International journal of cancer

authors： Melzner I,Weniger MA,Bucur AJ,Brüderlein S,Dorsch K,Hasel C,Leithäuser F,Ritz O,Dyer MJ,Barth TF,Möller P

更新日期：2006-04-15 00:00:00

abstract：:Allelic loss at the short arm of chromosome 11 is one of the most common and potent events in the progression and metastasis of breast cancer. Here, we present evidence that the Integrin-Linked Kinase (ILK) gene maps to the commonly deleted chromosome 11p15.5 and suppresses malignant growth of human breast cancer cell...

journal_title：International journal of cancer

authors： Chen P,Shen WZ,Karnik P

更新日期：2004-10-10 00:00:00

abstract：:To better inform the next clinical trials of vascular disrupting agent combretastatin-A4-phosphate (CA4P) in patients with hepatic malignancies, this preclinical study aimed at evaluating CA4P therapeutic efficacy in rats with primary hepatocellular carcinomas (HCCs) of a full spectrum of differentiation and vasculari...

journal_title：International journal of cancer

authors： Liu Y,De Keyzer F,Wang Y,Wang F,Feng Y,Chen F,Yu J,Liu J,Song S,Swinnen J,Bormans G,Oyen R,Huang G,Ni Y

更新日期：2018-10-01 00:00:00

abstract：:A segment of 712 bases coding for part of the human stearoyl-CoA desaturase gene was made by polymerase chain reaction (PCR) using primers based on published rat cDNA sequences. The human PCR product was confirmed by DNA sequencing. It was next cloned into a vector from which anti-sense, highly radioactive RNA transcr...

journal_title：International journal of cancer

authors： Li J,Ding SF,Habib NA,Fermor BF,Wood CB,Gilmour RS

更新日期：1994-05-01 00:00:00

abstract：:We have analyzed the BRAF locus on chromosome 7q34 with microsatellites for allelic changes and exons 11 and 15 of the BRAF with sequencing for mutations in 50 kidney cancers including 20 papillary, 15 conventional and 15 chromophobe renal cell carcinomas (RCC). Allelic changes at the BRAF locus were seen in 16 of the...

journal_title：International journal of cancer

authors： Nagy A,Balint I,Kovacs G

更新日期：2003-10-10 00:00:00

abstract：:The monoclonal antibody (MAb) 4F2 defines an oncofetal antigen in human fibroblastic cells. Two-dimensional electrophoretic analysis reveals that tumor cell lines from mesenchymal tissues co-express two or more heavy-chain molecular variants of the antigen whereas the light subunit (41 kDa) is not affected. Among norm...

journal_title：International journal of cancer

authors： Azzarone B,Eid P,Malpiece Y,Andeol Y,Fauci AS,Suarez H

更新日期：1986-08-15 00:00:00

abstract：:The aim of our study was to develop and validate a machine learning algorithm to predict response of individual HER2-amplified colorectal cancer liver metastases (lmCRC) undergoing dual HER2-targeted therapy. Twenty-four radiomics features were extracted after 3D manual segmentation of 141 lmCRC on pretreatment portal...

journal_title：International journal of cancer

authors： Giannini V,Rosati S,Defeudis A,Balestra G,Vassallo L,Cappello G,Mazzetti S,De Mattia C,Rizzetto F,Torresin A,Sartore-Bianchi A,Siena S,Vanzulli A,Leone F,Zagonel V,Marsoni S,Regge D

更新日期：2020-12-01 00:00:00

abstract：:Human papillomavirus (HPV) genomes usually persist as episomal molecules in HPV associated preneoplastic lesions whereas they are frequently integrated into the host cell genome in HPV-related cancers cells. This suggests that malignant conversion of HPV-infected epithelia is linked to recombination of cellular and vi...

journal_title：International journal of cancer

authors： Luft F,Klaes R,Nees M,Dürst M,Heilmann V,Melsheimer P,von Knebel Doeberitz M

更新日期：2001-04-01 00:00:00

abstract：:Epidemiological studies of in situ breast cancer are sparse, and the role of reproductive history, an established risk modifier for invasive breast cancer, remains incompletely investigated. To examine possible associations with parity and age at first birth, we undertook a case-control study nested in a nationwide co...

journal_title：International journal of cancer

authors： Lambe M,Hsieh CC,Tsaih SW,Ekbom A,Trichopoulos D,Adami HO

更新日期：1998-07-29 00:00:00

abstract：:High dietary intakes of calcium and dairy products have been hypothesized to enhance prostate cancer risk, but available prospective data regarding these associations are inconsistent. We examined dietary intakes of calcium and dairy products in relation to risk of prostate cancer in the Alpha-Tocopherol, Beta-Caroten...

journal_title：International journal of cancer

authors： Mitrou PN,Albanes D,Weinstein SJ,Pietinen P,Taylor PR,Virtamo J,Leitzmann MF

更新日期：2007-06-01 00:00:00

abstract：:The aim of this study was to determine whether the skin-sensitizing agent 2,4-dinitrofluorobenzene (DNFB) would elicit the same morphological and biochemical events that are characteristic of 12-O-tetradecanoylphorbol-13-acetate (TPA). While single applications of 0.1% or 0.2% DNFB produced only mild epidermal hyperpl...

journal_title：International journal of cancer

authors： Maldve RE,Fischer SM

更新日期：1995-02-08 00:00:00

abstract：:Knowledge about the prevalence of human papillomavirus (HPV) on a population level is important. We conducted a large population-based study in Denmark to determine the overall and age-specific HPV prevalence, and HPV type distribution in women. Liquid-based cytology samples (SurePath) were collected consecutively. HP...

journal_title：International journal of cancer

authors： Kjaer SK,Breugelmans G,Munk C,Junge J,Watson M,Iftner T

更新日期：2008-10-15 00:00:00

abstract：:A polymorphism at codon 72 of the p53 gene, resulting in either an arginine or a proline residue in the protein, has been reported to affect the susceptibility of p53 to human papillomavirus (HPV) E6-mediated degradation in cultured cells. However, the relevance of this polymorphism to naturally occurring HPV infectio...

journal_title：International journal of cancer

authors： Giannoudis A,Graham DA,Southern SA,Herrington CS

更新日期：1999-09-24 00:00:00

abstract：:During the 7th annual follow-up of our cohort of homosexual men in 1989, we tested the hypotheses that infection with human immunodeficiency virus (HIV) may enhance the expression of human papilloma virus (HPV) and that the development of anal epithelial abnormality is related to a biologic interaction between these t...

journal_title：International journal of cancer

authors： Caussy D,Goedert JJ,Palefsky J,Gonzales J,Rabkin CS,DiGioia RA,Sanchez WC,Grossman RJ,Colclough G,Wiktor SZ

更新日期：1990-08-15 00:00:00

abstract：:To investigate whether human melanoma cells intrinsically resistant to autologous LAKs do exist, and whether a relationship between the level of lysis of LAKs and spontaneous drug resistance can be identified at the clonal level, we studied 44 clones obtained from a metastatic melanoma lesion. The antigenic phenotype ...

journal_title：International journal of cancer

authors： Gambacorti-Passerini C,Rivoltini L,Supino R,Mariani M,Parmiani G

更新日期：1988-10-15 00:00:00

abstract：:We have identified a novel membrane-type matrix metalloproteinase (MT-MMP) expressed on the cell surface and inducing activation of pro-gelatinase A in vitro. In this study, we further examined the possibility that MT-MMP is the activator of pro-gelatinase A in tumors as well as in vitro. Expression of MT-MMP mRNA was...

journal_title：International journal of cancer

authors： Tokuraku M,Sato H,Murakami S,Okada Y,Watanabe Y,Seiki M

更新日期：1995-10-20 00:00:00

abstract：:Identification of loss of heterozygosity on specific genetic loci is crucial for understanding the pathogenesis of prostate cancer at the molecular level. This is especially important because the deleted regions may contain putative tumor suppressor genes. Chromosome 3p loss appears to be frequently associated with va...

journal_title：International journal of cancer

authors： Dahiya R,McCarville J,Hu W,Lee C,Chui RM,Kaur G,Deng G

更新日期：1997-03-28 00:00:00

abstract：:The causal role of wood-dust exposure in sinonasal cancer (SNC) has been established in epidemiological studies, but the mechanisms of SNC carcinogenesis are still largely unknown. Increased amounts of COX-2 are found in both premalignant and malignant tissues, and experimental evidence link COX-2 to development of ca...

journal_title：International journal of cancer

authors： Holmila R,Cyr D,Luce D,Heikkilä P,Dictor M,Steiniche T,Stjernvall T,Bornholdt J,Wallin H,Wolff H,Husgafvel-Pursiainen K

更新日期：2008-05-01 00:00:00

abstract：:Previous studies have been inconsistent with respect to the reported associations between phospho-Akt (p-Akt) overexpression and lung cancer prognosis. In this study, we conducted a systematic review and meta-analysis to assess the prognostic value of p-Akt in patients with non-small cell lung carcinoma (NSCLC). Relev...

journal_title：International journal of cancer

authors： Yang Y,Luo J,Zhai X,Fu Z,Tang Z,Liu L,Chen M,Zhu Y

更新日期：2014-09-15 00:00:00

abstract：:Loss of imprinting (LOI) of insulin-like growth factor 2 (IGF2) is a common event in many cancers and typically activates the maternally silenced allele. The resulting biallelic IGF2 expression correlates strongly with the hypomethylation of a differentially methylated region (DMR) near its promoter. It has also been ...

journal_title：International journal of cancer

authors： Cheng YW,Idrees K,Shattock R,Khan SA,Zeng Z,Brennan CW,Paty P,Barany F

更新日期：2010-08-01 00:00:00

abstract：:The ability of endogenously synthesized protoporphyrin IX (PpIX) to damage Chinese hamster lung fibroblasts of the line V79 by exposure to light was examined. This treatment induced reduction of cellular ATP, GTP, of the NADH/NAD+ ratio and of oxygen consumption. The present results indicate a close relationship betwe...

journal_title：International journal of cancer

authors： Shevchuk I,Chekulayev V,Moan J,Berg K

更新日期：1996-09-17 00:00:00

abstract：:This report describes maternal and perinatal risk factors for Wilms' tumor analyzed in a case-control study nested in a nationwide cohort in Sweden. The Swedish National Cancer Registry ascertained 110 cases from among successive birth cohorts from 1973 through 1984, identified by the Swedish Medical Birth Registry, t...

journal_title：International journal of cancer

authors： Lindblad P,Zack M,Adami HO,Ericson A

更新日期：1992-04-22 00:00:00

abstract：:The human polyomaviruses JC virus (JCV) and BK virus (BKV) are oncogenic in experimental systems and commonly infect humans. JCV DNA has been reported to be present in human colon mucosa and in colorectal cancers. To investigate whether the risk for colorectal cancer is associated with JCV or BKV infection, we perform...

journal_title：International journal of cancer

authors： Lundstig A,Stattin P,Persson K,Sasnauskas K,Viscidi RP,Gislefoss RE,Dillner J

更新日期：2007-09-01 00:00:00

abstract：:Although the existence of a humoral response against tumor-associated antigens is well appreciated, a systematic analysis of its possible induction by the tumor remains missing. We compared the specific IgG response of Stage IV melanoma patients during vaccination. Patients had been treated within 2 clinical trials wi...

journal_title：International journal of cancer

authors： Ehlken H,Schadendorf D,Eichmüller S

更新日期：2004-01-10 00:00:00

abstract：:The correlation between tumorigenicity and cell-surface adhesiveness was investigated in eight mouse fibroblastoid cell lines. Four of the lines (Mc 11-Mc 15) were derived from mouse MC-induced fibrosarcomas, two were derivatives of L cells (A9, A9HT), and two (clone 3 and clone 7 H7F4) were obtained by fusion of A9HT...

journal_title：International journal of cancer

authors： Bubeník J,Perlmann P,Fenyö EM,Jandlová T,Suhajová E,Malkovský M

更新日期：1979-03-15 00:00:00

abstract：:Our study was designed to examine the effects of IL-2 gene therapy in a surgical minimal residual tumour disease (SMRTD). Mice were inoculated s.c. with methylcholanthrene (MC)-induced MC12 sarcoma cells. When the tumours reached 8 to 12 mm in diameter, they were excised, either completely ("microscopic SMRTD") or inc...

journal_title：International journal of cancer

authors： Vlk V,Rössner P,Indrová M,Bubeník J,Sobota V

更新日期：1998-03-30 00:00:00

abstract：:In a series of consecutive 51chromium (51Cr) assays, 21 melanoma and 14 colo-rectal carcinoma patients were tested for their in vitro cell-mediated immune reactions to melanoma, rectal adenocarcinoma, and normal fibroblast target cells. Blood lymphocytes (BL) from four individuals were included in each experiment. In ...

journal_title：International journal of cancer

authors： Steele G Jr,Sjögren HO,Stadenberg I

更新日期：1976-01-15 00:00:00