Population-based prevalence, type- and age-specific distribution of HPV in women before introduction of an HPV-vaccination program in Denmark.

abstract：:Reverse-transcriptase polymerase chain reaction has been used to analyze the expression of 2 latent genes (EBNA-1 and LMP-1) and one replicative gene (BZLF-1) of Epstein-Barr virus in mononuclear cells from bone marrow and peripheral blood of healthy donors. EBV-gene transcription was detected in 8 out of 15 bone-marr...

journal_title：International journal of cancer

authors： Gonnella R,Angeloni A,Calogero A,Farina A,Santarelli R,Gentile G,Arcese W,Martino P,Mandelli F,Frati L,Faggioni A,Ragona G

更新日期：1997-03-04 00:00:00

abstract：:Previous studies have reported an association between hot tea drinking and risk of esophageal cancer, but no study has examined this association using prospectively and objectively measured tea drinking temperature. We examined the association of tea drinking temperature, measured both objectively and subjectively at ...

journal_title：International journal of cancer

authors： Islami F,Poustchi H,Pourshams A,Khoshnia M,Gharavi A,Kamangar F,Dawsey SM,Abnet CC,Brennan P,Sheikh M,Sotoudeh M,Nikmanesh A,Merat S,Etemadi A,Nasseri Moghaddam S,Pharoah PD,Ponder BA,Day NE,Jemal A,Boffetta P,Mal

更新日期：2020-01-01 00:00:00

abstract：:Owing to their role in controlling the efflux of toxic compounds, transporters are central players in the process of detoxification and elimination of xenobiotics, which in turn is related to cancer risk. Among these transporters, ATP-binding cassette B1/multidrug resistance 1 (ABCB1/MDR1), ABCC2/multidrug resistance ...

journal_title：International journal of cancer

authors： Campa D,Butterbach K,Slager SL,Skibola CF,de Sanjosé S,Benavente Y,Becker N,Foretova L,Maynadie M,Cocco P,Staines A,Kaaks R,Boffetta P,Brennan P,Conde L,Bracci PM,Caporaso NE,Strom SS,Camp NJ,Cerhan JR,GEC Consort

更新日期：2012-08-15 00:00:00

abstract：:Fibroblast growth factor 15 (FGF15), FGF19 in humans, is a gut-derived hormone and a key regulator of bile acids and carbohydrate metabolism. FGF15 also participates in liver regeneration after partial hepatectomy inducing hepatocellular proliferation. FGF19 is overexpressed in a significant proportion of human hepato...

journal_title：International journal of cancer

authors： Uriarte I,Latasa MU,Carotti S,Fernandez-Barrena MG,Garcia-Irigoyen O,Elizalde M,Urtasun R,Vespasiani-Gentilucci U,Morini S,de Mingo A,Mari M,Corrales FJ,Prieto J,Berasain C,Avila MA

更新日期：2015-05-15 00:00:00

abstract：:G-banding analyses of 14 independently derived B-cell lymphomas showed the frequent occurrence of chromosome 15 trisomy. It was present in seven of nine spontaneous B-cell lymphomas, but in company with other trisomies, monosomies and marker chromosomes. In five carcinogen-induced primary B-cell leukemias, trisomy 15 ...

journal_title：International journal of cancer

authors： Wiener F,Babonits M,Spira J,Bregula U,Klein G,Merwin RM,Asofsky R,Lynes M,Haughton G

更新日期：1981-01-15 00:00:00

abstract：:When sensitized leukocytes were re-exposed to EBV antigen or to tuberculin-purified protein derivatives, they produced lymphokines, including the migration inhibition factor, which inhibited the migration of guinea-pig peritoneal exudate cells, and other lymphokines with the characteristics of interferon, which inhibi...

journal_title：International journal of cancer

authors： Lai PK,Alpers MP,MacKay-Scollay EM

更新日期：1977-07-15 00:00:00

abstract：:In order to establish the role of human papillomavirus (HPV) in carcinogenesis of epidermodysplasia verruciformis (EV), the presence, the molecular characteristics and the physical state of HPV DNA in a benign lesion, a primary carcinoma and a metastatic carcinoma developing in the same EV patient were studied and com...

journal_title：International journal of cancer

authors： Yabe Y,Tanimura Y,Sakai A,Hitsumoto T,Nohara N

更新日期：1989-06-15 00:00:00

abstract：:Drug-induced DNA demethylation in normal human cells and inherited localized hypomethylation in mitogen-stimulated lymphocytes from patients with a rare recessive disease (ICF: immunodeficiency, centromeric region instability, facial anomalies) are associated with karyotypic instability. This chromosomal recombination...

journal_title：International journal of cancer

authors： Narayan A,Ji W,Zhang XY,Marrogi A,Graff JR,Baylin SB,Ehrlich M

更新日期：1998-09-11 00:00:00

abstract：:Dichlorodiphenyltrichloroethane (p,p'-DDT), an organochlorine pesticide known to have deleterious health effects in humans, has been linked to hepatocellular carcinoma (HCC) in rodents. A recent study has reported that p,p'-DDT and its most persistent metabolite, dichlorodiphenyldichloroethylene (p,p'-DDE), may also b...

journal_title：International journal of cancer

authors： Persson EC,Graubard BI,Evans AA,London WT,Weber JP,LeBlanc A,Chen G,Lin W,McGlynn KA

更新日期：2012-11-01 00:00:00

abstract：:The role of alcoholic beverages in the etiology of gastric cancer is unclear. Recent summaries showed a positive association between higher alcohol intake and gastric cancer risk, but the magnitude of association is small, there is moderate heterogeneity among studies, and most cases were from Asian populations. We pr...

journal_title：International journal of cancer

authors： Wang S,Freedman ND,Loftfield E,Hua X,Abnet CC

更新日期：2018-12-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most common malignancy representing 90% of all forms of oral cancer worldwide. Although great efforts have been made in the past decades, the 5-year survival rate of OSCC patients is no more than 60% due to tumor metastasis and subsequent recurrence. The metastasis from the p...

journal_title：International journal of cancer

authors： Ling Z,Cheng B,Tao X

更新日期：2020-10-22 00:00:00

abstract：:To generate broad eating patterns, which could explain more adequately the breast cancer etiology, we conducted an exploratory factor analysis in Montevideo, Uruguay. The study included 442 newly diagnosed and microscopically confirmed cases with breast cancer and 442 hospitalized controls, with non-neoplastic disease...

journal_title：International journal of cancer

authors： Ronco AL,De Stefani E,Boffetta P,Deneo-Pellegrini H,Acosta G,Mendilaharsu M

更新日期：2006-10-01 00:00:00

abstract：:Increased exposure to estrogen is a risk factor for postmenopausal breast cancer, and dietary factors can influence estrogen metabolism. However, studies of diet and breast cancer have been inconclusive. We developed a dietary pattern associated with levels of unconjugated estradiol and the ratio of 2- and 16-hydroxyl...

journal_title：International journal of cancer

authors： Guinter MA,McLain AC,Merchant AT,Sandler DP,Steck SE

更新日期：2018-08-01 00:00:00

abstract：:A glucuronide doxorubicin prodrug N-[4-doxorubicin-N-carbonyl (oxymethyl) phenyl] O-beta-glucuronyl carbamate (DOX-GA3) has been developed to improve the antitumor effects of doxorubicin (DOX). The prodrug was originally designed to be activated into drug by human beta-glucuronidase (GUS) released from tumor cells in ...

journal_title：International journal of cancer

authors： Houba PH,Boven E,van der Meulen-Muileman IH,Leenders RG,Scheeren JW,Pinedo HM,Haisma HJ

更新日期：2001-02-15 00:00:00

abstract：:Caveolae have been indicated as a center of cytoskeleton regulation for Src kinase/Rho GTPase signaling. In addition, Src recruitment on intact cortical actin cytoskeleton appears to be required for bFGF/FGFR signal activation. Recently, we established a relationship between caveolin-1 (Cav-1) expression and cell migr...

journal_title：International journal of cancer

authors： Fecchi K,Travaglione S,Spadaro F,Quattrini A,Parolini I,Piccaro G,Raggi C,Fabbri A,Felicetti F,Carè A,Fiorentini C,Sargiacomo M

更新日期：2012-03-15 00:00:00

abstract：:Very recently, BRAF mutations were found in about 2/3 of malignant melanomas and at lower frequencies in other human cancers. The BRAF gene codes for a protein in the mitogen-activated protein kinase (MAPK) pathway. All mutations identified to date are within the kinase domain, with a single missense mutation (V599E) ...

journal_title：International journal of cancer

authors： Meyer P,Klaes R,Schmitt C,Boettger MB,Garbe C

更新日期：2003-08-10 00:00:00

abstract：:Sunlight is essential for the production of vitamin D in the body. Evidence exists to suggest that vitamin D metabolites may have a role in tumor growth suppression. In this large study, involving over a million cancer patients from the United Kingdom, we have analyzed the role of season of diagnosis and sunlight expo...

journal_title：International journal of cancer

authors： Lim HS,Roychoudhuri R,Peto J,Schwartz G,Baade P,Møller H

更新日期：2006-10-01 00:00:00

abstract：:The purpose of this study was to induce in postnatal life the selective growth of altered hepatocytic populations which had been induced in utero by various chemicals. Pregnant rats of a Wistar strain were given a single dose of various chemical carcinogens on the 18th gestational day. From two months postpartum, both...

journal_title：International journal of cancer

authors： Ogawa K,Yokokawa K,Tomoyori T,Onoé T

更新日期：1982-03-15 00:00:00

abstract：:To identify tumor-suppressor genes on chromosome 10 in non-small cell lung cancers, we isolated 10 types of splicing variant of the HELLS/SMARCA6 gene transcripts. HELLS/SMARCA6 is a novel member of SNF2 family, which is implicated in cellular functions like chromatin remodeling. Variant 1 was an alternatively spliced...

journal_title：International journal of cancer

authors： Yano M,Ouchida M,Shigematsu H,Tanaka N,Ichimura K,Kobayashi K,Inaki Y,Toyooka S,Tsukuda K,Shimizu N,Shimizu K

更新日期：2004-10-20 00:00:00

abstract：:Multidrug resistance, the phenomenon by which cells treated with a drug become resistant to the cytotoxic effect of a variety of other structurally and functionally unrelated drugs, is often associated with the expression of P-glycoprotein, an efflux membrane pump coded by the MDR1 (ABCB1) gene. Transcription from MDR...

journal_title：International journal of cancer

authors： Raguz S,Randle RA,Sharpe ER,Foekens JA,Sieuwerts AM,Meijer-van Gelder ME,Melo JV,Higgins CF,Yagüe E

更新日期：2008-03-01 00:00:00

abstract：:Colorectal cancer (CRC) screening rates are currently suboptimal. Blood-based screening could improve rates of earlier detection for CRC and adenomatous colorectal polyps. In this study, we evaluated the feasibility of plasma-based detection of early CRC and adenomatous polyps using array-mediated analysis methylation...

journal_title：International journal of cancer

authors： Cassinotti E,Melson J,Liggett T,Melnikov A,Yi Q,Replogle C,Mobarhan S,Boni L,Segato S,Levenson V

更新日期：2012-09-01 00:00:00

abstract：:RAS, TP53 (p53) and MYC are among the most frequently altered driver genes in cancer. Thus, RAS is the most frequently mutated oncogene, MYC the most frequently amplified gene and TP53 the most frequently mutated tumor suppressor gene and overall the most frequently mutated gene in cancer. Theoretically, therefore, th...

journal_title：International journal of cancer

authors： Duffy MJ,Crown J

更新日期：2021-01-01 00:00:00

abstract：:Although the net benefits of tamoxifen in adjuvant breast cancer therapy have been proven, the recurrence of the cancer in an aggressive and hormone independent form has been highly problematic. We previously demonstrated the important role mitochondrial DNA (mtDNA) plays in hormone-independence in prostate cancer. He...

journal_title：International journal of cancer

authors： Naito A,Carcel-Trullols J,Xie CH,Evans TT,Mizumachi T,Higuchi M

更新日期：2008-04-01 00:00:00

abstract：:The intrauterine environment appears to play a role in the development of adult diseases, including several prominent cancers. Our study aims to characterize the relationship between birth weight, a measure of the intrauterine environment, and adult obesity. A population-based sample of women aged 50-79, living in the...

journal_title：International journal of cancer

authors： Leong NM,Mignone LI,Newcomb PA,Titus-Ernstoff L,Baron JA,Trentham-Dietz A,Stampfer MJ,Willett WC,Egan KM

更新日期：2003-03-01 00:00:00

abstract：:A human revertant cell line, derived from non-producer human osteosarcoma cells (NP/KHOS) induced by Kirsten murine sarcoma virus, was treated in vitro with various levels of polycyclic aromatic hydrocarbons (3-methylcholanthrene, 7,12-dimethylbenz(alpha)anthracene, and benzo(alpha)pyrene [BP] or dimethyl sulfoxide (c...

journal_title：International journal of cancer

authors： Cho HY,Arnstein P,Rhim JS

更新日期：1978-01-15 00:00:00

abstract：:Serum vitamin D3-binding protein (Gc protein) is the precursor for the principal macrophage activating factor (MAF). The MAF precursor activity of serum Gc protein of breast cancer patients was lost or reduced because Gc protein was deglycosylated by serum alpha-N-acetylgalactosaminidase (Nagalase) secreted from cance...

journal_title：International journal of cancer

authors： Yamamoto N,Suyama H,Yamamoto N,Ushijima N

更新日期：2008-01-15 00:00:00

abstract：:Prostate cancer incidence has increased during recent years, possibly linked to environmental exposures. Exposure to environmental carcinogens is unlikely to be evenly distributed geographically, which may give rise to variations in disease occurrence that is detectable in a spatial analysis. The aim of our study was ...

journal_title：International journal of cancer

authors： Jarup L,Best N,Toledano MB,Wakefield J,Elliott P

更新日期：2002-02-10 00:00:00

abstract：:Melanoma is a highly malignant and increasingly common neoplasm. Because metastatic melanoma remains incurable, new treatment approaches are needed. Immunoliposomes have been previously shown to enhance the selective localization of immunoliposome-entrapped drugs to solid tumors with improvements in the therapeutic in...

journal_title：International journal of cancer

authors： Pagnan G,Montaldo PG,Pastorino F,Raffaghello L,Kirchmeier M,Allen TM,Ponzoni M

更新日期：1999-04-12 00:00:00

abstract：:We recently reported the potential of genistein in augmenting gemcitabine-induced killing of pancreatic cancer (Banerjee, S. et al., Cancer Research 2005;65:9064-72). Since cis-diaminedichloroplatinum (II) (cisplatin) is widely used against solid tumors, we further investigated whether genistein pretreatment could be ...

journal_title：International journal of cancer

authors： Banerjee S,Zhang Y,Wang Z,Che M,Chiao PJ,Abbruzzese JL,Sarkar FH

更新日期：2007-02-15 00:00:00

abstract：:Leukocyte-transforming agents were isolated in baboon leukocytes inoculated with oral excretions from immunosuppressed chimpanzees. The transformed lymphoblasts had B cell surface markers and harbored herpes-type virus particles; 5-10% of the cells contained cytoplasmic antigens reactive with Epstein-Barr virus (EBV)-...

journal_title：International journal of cancer

authors： Gerber P,Kalter SS,Schidlovsky G,Peterson WD Jr,Daniel MD

更新日期：1977-09-15 00:00:00