Dichlorodiphenyltrichloroethane and risk of hepatocellular carcinoma.

abstract：:Using a microarray technique, we found decorin to be underexpressed, but osteopontin (OPN) to be overexpressed, in esophageal squamous cell carcinoma (ESCC). This study aims to examine whether plasma decorin and OPN plus personal substances use (tobacco, alcohol and areca) can serve as suitable clinical markers to pre...

journal_title：International journal of cancer

authors： Wu IC,Wu DC,Huang CC,Lin HS,Chen YK,Tsai HJ,Lu CY,Chou SH,Chou YP,Li LH,Tai SY,Wu MT

更新日期：2010-11-01 00:00:00

abstract：:Molecular markers predictive of prostate cancer prognosis are urgently needed. Overexpression of the antiapoptotic protein, Bcl-2, has repeatedly been shown to be associated with adverse outcome in this malignancy. We hypothesized that a regulatory BCL2 -938C>A promoter polymorphism, which significantly affects promot...

journal_title：International journal of cancer

authors： Bachmann HS,Heukamp LC,Schmitz KJ,Hilburn CF,Kahl P,Buettner R,Nückel H,Eisenhardt A,Rübben H,Schmid KW,Siffert W,Eggert A,Schramm A,Schulte JH

更新日期：2011-11-15 00:00:00

abstract：:HPP1 is a recently discovered gene that is epigenetically silenced in a number of tumor types, suggesting a potential role as a tumor suppressor. However, whether HPP1 has tumor suppressor activity is not clearly known. We have sought to investigate the effects of HPP1 on tumor growth and survival and to identify sign...

journal_title：International journal of cancer

authors： Elahi A,Zhang L,Yeatman TJ,Gery S,Sebti S,Shibata D

更新日期：2008-04-01 00:00:00

abstract：:The most recent data available demonstrate a 120-fold difference between the lowest and highest incidence rates of prostatic cancer, the disease being very common in North America, particularly among Blacks, and in Scandinavia, while it is rare in Japan and other oriental countries. The highest mortality for prostatic...

journal_title：International journal of cancer

authors： Zaridze DG,Boyle P,Smans M

更新日期：1984-02-15 00:00:00

abstract：:We show that siRNA-mediated suppression of protein tyrosine phosphatase alpha (PTP alpha) reduces Src activity 2 to 4-fold in breast, colon and other human cancer cell lines. Src and PTP alpha RNAi induced apoptosis in estrogen receptor (ER)-negative breast cancer and colon cancer cells, but not in immortalized noncan...

journal_title：International journal of cancer

authors： Zheng X,Resnick RJ,Shalloway D

更新日期：2008-05-01 00:00:00

abstract：:Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Tumor recurrence occurs in ∼20% of PTCs and some reach advanced stages. Promoter mutation in the telomerase reverse transcriptase (TERT) gene is identified to be a prognostic marker in PTC. However, the contribution of TERT promoter mutation ...

journal_title：International journal of cancer

authors： Bu R,Siraj AK,Divya SP,Kong Y,Parvathareddy SK,Al-Rasheed M,Al-Obaisi KAS,Victoria IG,Al-Sobhi SS,Al-Dawish M,Al-Dayel F,Al-Kuraya KS

更新日期：2018-05-15 00:00:00

abstract：:Biopsies of 13 penile cancers (PC), from patients living in regions of Uganda with a high incidence of genital cancers, were studied for the presence, molecular characteristics and physical state of DNA related to that of human papillomavirus (HPV) types 6, 11, 16, 18, 31 and 33. HPV DNA sequences were detected in all...

journal_title：International journal of cancer

authors： Tornesello ML,Buonaguro FM,Beth-Giraldo E,Kyalwazi SK,Giraldo G

更新日期：1992-06-19 00:00:00

abstract：:The results from the population-based cancer registry for the city of Ho Chi Minh in 1995-1996 represent the first information on the incidence of cancer in southern Viet Nam. A total of 4,080 cancer cases in males and 4,338 in females were registered, corresponding to age-standardized incidence rates (ASRs) of 130.9 ...

journal_title：International journal of cancer

authors： Nguyen QM,Nguyen HC,Parkin DM

更新日期：1998-05-18 00:00:00

abstract：:To monitor recent trends in oral and pharyngeal cancer mortality in 38 European countries, we analyzed data provided by the World Health Organization over the period 1975-2004. Joinpoint analysis was used to identify significant changes in trends. In the European Union (EU), male mortality rates rose by 2.1% per year ...

journal_title：International journal of cancer

authors： Garavello W,Bertuccio P,Levi F,Lucchini F,Bosetti C,Malvezzi M,Negri E,La Vecchia C

更新日期：2010-07-01 00:00:00

abstract：:To investigate the association of childhood ALL and SES, we collected data on 507 children aged 0-14 years diagnosed with ALL between 1997 and 2002 from the population-based Cancer Registry of São Paulo, Brazil, covering 96 districts. Each child was assigned to an SES category based on the district of residence at dia...

journal_title：International journal of cancer

authors： Ribeiro KB,Buffler PA,Metayer C

更新日期：2008-10-15 00:00:00

abstract：:Regulation of cell differentiation is most often impaired in malignant tumors and may represent a key mechanism for the progression of the disease. CCAAT-enhancer binding protein (C/EBP) is a family of transcription factors involved in the regulation of embryonic gut development in rodents, which has also been detecte...

journal_title：International journal of cancer

authors： Rask K,Thörn M,Pontén F,Kraaz W,Sundfeldt K,Hedin L,Enerbäck S

更新日期：2000-05-01 00:00:00

abstract：:Monocytes from the peripheral blood of 10 normal adult human donors were tested for their cytolytic activity on untransformed or SV40-transformed, early passage, human fibroblasts. Two pairs of human fibroblast lines (2303 and SV40-2303, 2931 and SV40-2931) were used and lysis was assessed in terms of release of [3H]t...

journal_title：International journal of cancer

authors： Mantovani A,Tagliabue A,Dean JH,Jerrells TR,Herberman RB

更新日期：1979-01-15 00:00:00

abstract：:Numerous prospective and retrospective studies have clearly demonstrated a dose-related increased lung cancer risk associated with cigarette smoking, with evidence also for a genetic component to risk. In this study, using the two-stage clonal expansion stochastic model framework, for the first time we investigated th...

journal_title：International journal of cancer

authors： Deng L,Kimmel M,Foy M,Spitz M,Wei Q,Gorlova O

更新日期：2009-05-01 00:00:00

abstract：:During 2000, marine antitumor pharmacology research aimed at the discovery of novel antitumor agents was published in 85 peer-reviewed articles. The purpose of this article is to present a structured review of the antitumor and cytotoxic properties of 143 marine natural products, many of them novel compounds that belo...

journal_title：International journal of cancer

authors： Mayer AM,Gustafson KR

更新日期：2003-06-20 00:00:00

abstract：:A population-based case-control study of risk factors for renal-cell carcinoma was conducted in Denmark from 1989 to 1992. A total of 368 histologically verified cases and 396 controls were included. Information on weight, height, physical activity and reproductive factors were collected in a structured interview, alo...

journal_title：International journal of cancer

authors： Mellemgaard A,Engholm G,McLaughlin JK,Olsen JH

更新日期：1994-01-02 00:00:00

abstract：:Long-term survivors of childhood cancer suffer from a higher mortality than the general population. Here we evaluate late and very late mortality, and patterns of causes of death, in 5-year survivors after childhood and adolescent cancer in cases diagnosed during four decades in the five Nordic countries. The study is...

journal_title：International journal of cancer

authors： Garwicz S,Anderson H,Olsen JH,Winther JF,Sankila R,Langmark F,Tryggvadóttir L,Möller TR,Association of the Nordic Cancer Registries.,Nordic Society for Pediatric Hematology Oncology.

更新日期：2012-10-01 00:00:00

abstract：:We have previously described an inverse relationship between Cu-Zn superoxide dismutase (SOD) activity and invasiveness of a clone of human tongue cancer cells. In these cells, suppression of Cu-Zn SOD activity by transfection with anti-sense cDNA enhanced motility in vitro. The present studies were undertaken to dete...

journal_title：International journal of cancer

authors： Tanaka M,Kogawa K,Nishihori Y,Kuribayashi K,Nakamura K,Muramatsu H,Koike K,Sakamaki S,Niitsu Y

更新日期：1997-10-09 00:00:00

abstract：:Non-neoplastic mesenchymal cells, along with 33 benign and 87 malignant soft-tissue tumors (STT) were examined for expression of HLA-A,B,C, beta 2-microglobulin (beta 2m), HLA-DR, -DP, and -DQ molecules and the HLA-D associated invariant chain (Ii). Serial frozen sections were immunostained using monoclonal antibodies...

journal_title：International journal of cancer

authors： Mechtersheimer G,Staudter M,Majdic O,Dörken B,Moldenhauer G,Möller P

更新日期：1990-11-15 00:00:00

abstract：:MicroRNAs (mirs) are small noncoding RNA molecules (~22 nucleotides) that regulate posttranscriptional gene expression. Currently, there has not been a comprehensive study of their role in primary head and neck squamous cell carcinoma (HNSCC). To determine the role of mirs in HNSCC, we screened for altered microRNA ex...

journal_title：International journal of cancer

authors： Chang SS,Jiang WW,Smith I,Poeta LM,Begum S,Glazer C,Shan S,Westra W,Sidransky D,Califano JA

更新日期：2008-12-15 00:00:00

abstract：:G protein-coupled estrogen receptor-1 (GPER), a member of the G protein-coupled receptor (GPCR) superfamily, mediates estrogen-induced proliferation of normal and malignant breast epithelial cells. However, its role in breast cancer stem cells (BCSCs) remains unclear. Here we showed greater expression of GPER in BCSCs...

journal_title：International journal of cancer

authors： Chan YT,Lai AC,Lin RJ,Wang YH,Wang YT,Chang WW,Wu HY,Lin YJ,Chang WY,Wu JC,Yu JC,Chen YJ,Yu AL

更新日期：2020-03-15 00:00:00

abstract：:Nuclear factor-κB (NF-κB) is constitutively activated in many cancers, including oral squamous cell carcinoma (OSCC), and is involved in the invasive characteristics of OSCC, such as growth, antiapoptotic activity and protease production. However, the cellular mechanism underlying NF-κB's promotion of bone invasion by...

journal_title：International journal of cancer

authors： Furuta H,Osawa K,Shin M,Ishikawa A,Matsuo K,Khan M,Aoki K,Ohya K,Okamoto M,Tominaga K,Takahashi T,Nakanishi O,Jimi E

更新日期：2012-09-01 00:00:00

abstract：:The results of a survey of a population with a high incidence of oral and oesophageal cancer are presented. The population under study appears to have several epidemiologic characteristics, some of which may be associated with a high incidence of oral and oesophageal cancer. A remarkably high proportion (41%) of the m...

journal_title：International journal of cancer

authors： Zaridze DG,Blettner M,Trapeznikov NN,Kuvshinov JP,Matiakin EG,Poljakov BP,Poddubni BK,Parshikova SM,Rottenberg VI,Chamrakulov FS

更新日期：1985-08-15 00:00:00

abstract：:Serum and tumor tissue from breast cancer patients were evaluated for the presence of alpha subunit of hCG, by means of the specific radioimmunoassay. Elevated serum levels occurred in 0/50 (0%) of normal female controls, 1/17 (6%) of patients with benign breast disease, 3/53 (6%) of patients with primary breast cance...

journal_title：International journal of cancer

authors： Shindelman JE,Ortmeyer AE,Wada HG,Stockdale F,Sussman HH

更新日期：1980-05-15 00:00:00

abstract：:Neuroblastoma (NB) is the most common extracranial solid tumor of childhood. In advanced disease stages, prognosis is poor and treatments have limited efficacy, thus novel strategies are warranted. The synthetic retinoid Fenretinide (HPR) induces apoptosis in NB and melanoma cell lines. We reported an in vitro potenti...

journal_title：International journal of cancer

authors： Raffaghello L,Pagnan G,Pastorino F,Cosimo E,Brignole C,Marimpietri D,Montaldo PG,Gambini C,Allen TM,Bogenmann E,Ponzoni M

更新日期：2003-05-01 00:00:00

abstract：:Cervical cancer screening will rely, increasingly, on HPV testing as a primary screen. The requirement for triage tests which can delineate clinically significant infection is thus prescient. In this EUROGIN 2017 roadmap, justification behind the most evidenced triages is outlined, as are challenges for implementation...

journal_title：International journal of cancer

authors： Cuschieri K,Ronco G,Lorincz A,Smith L,Ogilvie G,Mirabello L,Carozzi F,Cubie H,Wentzensen N,Snijders P,Arbyn M,Monsonego J,Franceschi S

更新日期：2018-08-15 00:00:00

abstract：:In mice as well as humans, cytotoxic T lymphocytes (CTL) specific for wild-type-sequence (wt) p53 peptides have been shown to react against a wide range of tumors, but not normal cells. As such, they are attractive candidates for developing broadly applicable cancer vaccines. Of particular interest is the potential of...

journal_title：International journal of cancer

authors： Cicinnati VR,Dworacki G,Albers A,Beckebaum S,Tüting T,Kaczmarek E,DeLeo AB

更新日期：2005-03-01 00:00:00

abstract：:The loss of E-cadherin expression and the translocation of beta-catenin to the nucleus are frequently associated with the metastatic conversion of epithelial cells. In the nucleus, beta-catenin binds to the TCF/LEF-1 (T-cell factor/ lymphoid enhancer factor) transcription factor family resulting in the activation of s...

journal_title：International journal of cancer

authors： Mestdagt M,Polette M,Buttice G,Noël A,Ueda A,Foidart JM,Gilles C

更新日期：2006-01-01 00:00:00

abstract：:The effects of androgen manipulation on epidermal growth factor (EGF) receptor, p185erbB-2 and transforming growth factor-alpha (TGF-alpha) levels were examined in prostatic adenocarcinoma. Male nude mice were inoculated with the CWR22 androgen-dependent human prostatic tumor or an androgen-independent (CWR22R) deriva...

journal_title：International journal of cancer

authors： Myers RB,Oelschlager D,Manne U,Coan PN,Weiss H,Grizzle WE

更新日期：1999-07-30 00:00:00

abstract：:We studied the in vivo growth-inhibitory effect of the new S-adenosylmethionine decarboxylase inhibitor 4-amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A). L1210-bearing DBA-2 mice were treated with increasing CGP 48664A doses from 1 day after i.p. L1210 cell inoculation. Treatment was continued for 4 days, after w...

journal_title：International journal of cancer

authors： Dorhout B,Te Velde RJ,Ferwerda H,Kingma AW,De Hoog E,Muskiet FA

更新日期：1995-04-10 00:00:00

abstract：:Therapy-induced senescence (TIS) as a permanent growth arrest can be induced by various stimuli, including anticancer compounds. TIS emerged as a promising strategy to overcome resistance phenomena. However, senescent cancer cells might regain proliferation activity in vivo or even secrete tumor-promoting cytokines. T...

journal_title：International journal of cancer

authors： Weiland T,Lampe J,Essmann F,Venturelli S,Berger A,Bossow S,Berchtold S,Schulze-Osthoff K,Lauer UM,Bitzer M

更新日期：2014-01-01 00:00:00