Abstract:
:The reactivity of complement (C) with housedust allergen has been investigated in separate groups of sera from atopic patients with seasonal hay fever, bronchial asthma, atopic dermatitis, animal dander allergy or asthmatic bronchitis as compared to controls. Complement consumption was more pronounced on average in the allergy groups, with the exception of atopic dermatitis. Total IgE levels were elevated in all groups, especially in atopic dermatitis. There was no correlation between C-sensitivity and IgE data (RAST and RIST). The mean levels of C1-inhibitor, 1-antitrypsin and 2-marcroglobulin in the atopic group were found normal. A significant correlation was found between the extent of C-consumption by house dust allergen and the level of C4 in sera. It is concluded that both C and IgE differ from normal in atopic patients, but that neither one is suited for the routine diagnosis of atopy in individual serum samples.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Berrens L,Schoonenwolf DA,Bruynzeel PLsubject
Has Abstractpub_date
1978-01-01 00:00:00pages
45-54issue
1eissn
0301-0546issn
1578-1267journal_volume
6pub_type
杂志文章abstract::The authors selected 28 severe asthmatic children in order to compare the effect of different prophylactic regimens. Patients experiencing at least one wheezing attack per week were included in the study. In a randomized manner, they were allocated Zaditen or Intal. After 8 weeks of active treatment and a 2 week wash-...
journal_title:Allergologia et immunopathologia
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1983-01-01 00:00:00
abstract::An analysis is made of the effectiveness of terfenadine at dosages of 60 and 120 mg, of cetirizine at a dose of 10 mg, and of loratadine and ebastine at a dose of 10 mg in inhibiting the papule induced by 20 mcg of intradermal histamine. Although all produced significant inhibition, cetirizine and terfenadine 120 mg s...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::This study investigated the specificity and efficacy of immunotherapy with Artemisia vulgaris (Artemisia) extract. We studied 25 patients with a more than two year lasting history of seasonal rhinoconjunctivitis and who had only two clinically important allergies, either to Artemisia and Betula verrucosa (Betula) or t...
journal_title:Allergologia et immunopathologia
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:Peripheral blood B cells include lymphocytes at various stages of differentiation, each with a specific function in the immune response. All these stages show variations in percentage and absolute number throughout human life. The numbers and proportions of B subpopulation are influenced by factors such as g...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2016.05.003
更新日期:2016-01-01 00:00:00
abstract::A variety of antiasthmatic drugs were examined in a bioassay of uterine cornua of rats for determining their influence upon Bradykinin induced contractions. 4 different actions were seen: pronounced, moderate and weak suppression of enhancement of Bradykinin-activity. The most pronounced blocking effect was seen with ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1982-11-01 00:00:00
abstract:BACKGROUND:Although it has been hypothesized that infections may play a preventive role in allergic diseases, the role of Helicobacter pylori (H. pylori) is not clear. In this study we aimed to determine the association between H. pylori infection and allergic inflammation. METHODS:H. pylori infection was assessed in ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1157/13120393
更新日期:2008-03-01 00:00:00
abstract::The study was performed on 22 patients with sensitivity to aspirin which manifested as urticaria and angioedema. Sensitivity to aspirin was established based on the anamnesis of urticaria and angioedema occurring after ingestion of aspirin and oral challenge tests with acetylsalicylic acid. At first, the threshold dos...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1988-09-01 00:00:00
abstract::This study reports on the usefulness of skin mast cell quantification (mast cells(mm2) as a parameter for the diagnosis of atopic dermatitis (AD) and for determining the efficacy of the therapeutic measures employed. Fifteen children with AD of moderate to extreme severity, and which started within the first two years...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:Atopic dermatitis is a common illness in childhood. Children with atopic dermatitis are prone to develop cutaneous sensitization due to skin barrier dysfunction. AIM:The aim of this study was to evaluate the frequency of cutaneous sensitizations in patients with atopic dermatitis and to identify the most fr...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2018.06.002
更新日期:2019-01-01 00:00:00
abstract::Asthma morbidity and mortality has increased. One of the possible causes is the excessive use of beta agonists. The aim of this study is to compare the effects of six week treatment with beclomethasone alone (Ibec) or the combination of beclomethasone-salmeterol (Ibe + Isal) on serum potassium (K), CPK-MB and ECG in c...
journal_title:Allergologia et immunopathologia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0301-0546(01)79010-6
更新日期:2001-01-01 00:00:00
abstract::Excessive accumulation of histamine in the body leads to miscellaneous symptoms mediated by its bond to corresponding receptors (H1-H4). Increased concentration of histamine in blood can occur in healthy individuals after ingestion of foods with high contents of histamine, leading to histamine intoxication. In individ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/j.aller.2015.05.001
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:According to current knowledge, asthma is basically an inflammatory process. Its causes and physiopathological mechanisms are various. The final result is a recurrent obstructive bronchial process, with sibilants and/or dypnea, which causes an upset in functional respiratory tests, among which the maximum re...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(04)79240-x
更新日期:2004-07-01 00:00:00
abstract::Chronic bronchitis is a disease related to numerous etiologic factors: infections, climate influence, air pollution, cigarette smoking, etc. From a pathogenetic point of view, chronic bronchitis is generally considered as the phlogistic resultant of various irritative conditions, with a characteristic neutrophil compo...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND:Atopic dermatitis (AD) is most common in the first year of life. The aim of this study was to determine the prevalence of and risk factors for AD in a birth cohort of infants from southeast Turkey. METHODS:Adana Paediatric Allergy Research (ADAPAR) birth cohort study was derived from 1377 infants who were b...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2015.07.002
更新日期:2016-05-01 00:00:00
abstract::The increasingly extensive use of selective serotonin reuptake inhibitors will probably increase the number of cases of cutaneous reactions due to these drugs. This report describes a case of generalized exanthema due to paroxetine. Positive results to patch tests indicated delayed hypersensitivity. ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(06)73527-3
更新日期:2006-05-01 00:00:00
abstract::In a study carried out between 1982-1986, 68 asthmatic patients of different ages were followed-up in the Outpatient Department of the King Fahd University Hospital, Al-Khobar. Fifty-two patients were Saudis (78%) while the rest were of other nationalities (22%). The sex distribution was 39 (55.9%) females and 30 male...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1987-11-01 00:00:00
abstract::In 1975, Miller and Nussenzweig described a new function of the Complement (C'): the Capacity of this substance to solubilize "in vitro" antigen/antibody complexes previously formed. Subsequent studies of these authors and other researches (particularly Takahashi and his group) demonstrated that this process is mediat...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:
更新日期:1994-09-01 00:00:00
abstract::The modulation by norepinephrine and serotonin of the persistent antibody response to autologous and heterologous erythrocytes has been studied in [(C27Bl6xCBA/Ca) F1] mice. Serotonin (subcutaneously administered) transiently decreased the response to both autologous erythrocytes and rat erythrocytes; nevertheless, in...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND:Since gamma interferon release assays (IGRAs) cannot differentiate between active tuberculosis and latent tuberculosis infection (LTBI), development of rapid and specific diagnosis tools are essential for discriminating between active tuberculosis (TB) from LTBI. Both IGRAs are based on Mycobacterium tubercu...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2015.09.004
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Epidemiological evidence suggests the existence of a direct link between allergic rhinitis (AR) and asthma. Several studies also support the presence of small-airway dysfunction (SAD) in non-asthmatic children with AR. However, it remains unknown whether SAD can predict the progression of AR to asthma. Our o...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2017.09.025
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:It is thought that airway inflammation is more common in obese asthmatic patients because inflammation is harder to control and does not respond well to glucocorticoid treatment. OBJECTIVE:This study's aim was to investigate the effect of obesity on airway and systemic inflammation in children with asthma a...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2017.01.013
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Asthma hospitalization rates in Chilean children have increased in the last 14 years, but little is known about the factors associated with this. OBJECTIVE:Describe clinical characteristics of children hospitalized for asthma exacerbation. METHODS:Observational prospective cohort study in 14 hospitals. Ove...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.aller.2018.02.006
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Macrolides are useful in a wide range of bacterial infections including upper and lower respiratory tract, skin, and sexually transmitted diseases and are used in Helicobacter pylori eradication regimen. Skin symptoms occurring during drug therapy are mostly attributed to the antibiotic, causing considerable...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2010.06.008
更新日期:2011-07-01 00:00:00
abstract::Five patients with atopic dermatitis, three males and two females, aged 2 to 17 years, had positive reactions to air allergens (Dermatophagoides pteronyssinus and/or farinae). All the patients suffered from severe recurrent dermatophytosis that responded poorly to antifungal treatment. The results of immunologic evalu...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(02)79135-0
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:The incidence of asthma is high, especially in young people, a population group that includes women of reproductive age. We reviewed recent publications on asthma control during pregnancy to avoid undesired effects on both the mother and fetus. The prevalence of rhinoconjunctivitis is also high, although thi...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1157/13075700
更新日期:2005-05-01 00:00:00
abstract::After isolating the soluble factors and observing their biological activity of "in vitro" IgE synthesis, we decided to study the changes these molecules exercise on the expression of lymphocytes of IgE (FcR epsilon). We saw that the fractions from healthy subjects inhibited the expression of receptors quantified by im...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The results of the cutaneous tests with fungus, and the repercussion of the fungal allergens in asthma via inhalatory route has been a controversial subject for many years. The lack of characterization, purification and standardization of the allergens make the results of the cutaneous tests highly variable. The diagn...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1986-07-01 00:00:00
abstract::Specific immunotherapy consists of the administration of allergen extracts to patients with allergic disease to achieve clinical tolerance to the causative allergens. Currently, it is the only etiologic treatment for respiratory allergy. A World Health Organization opinion paper published in 1997 defines immunotherapy...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/s0301-0546(04)79300-3
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Asthma morbidity and mortality have been increasing. Data of asthma and respiratory mortality rates in Brazil are scarse. METHODS:We studied asthma and respiratory disease mortality rates in the state of So Paulo (capital and country side) from 1970 to 1996, as its relation with sales of drugs usually used ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(02)79084-8
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Pollens represent a rich source of proteins that are also potential elicitors of IgE-mediated pollen allergy. Sensitisation to panallergens could play an important role in diagnosis and specific immunotherapy, because these molecules are present in different plant pollens and plant foods and have marked stru...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2015.05.002
更新日期:2016-03-01 00:00:00