Abstract:
BACKGROUND:Peripheral blood B cells include lymphocytes at various stages of differentiation, each with a specific function in the immune response. All these stages show variations in percentage and absolute number throughout human life. The numbers and proportions of B subpopulation are influenced by factors such as gender, age, ethnicity, and lifestyle. This study establishes reference values according to age of peripheral blood B cell subtypes in healthy Mexican population. METHODS:Peripheral blood from healthy new-borns and adults were analysed for total B cell subpopulations, using surface markers such as CD19, IgM, IgD, CD21, CD24, CD27, and CD38, to identify naïve, memory with and without isotype switch, double-negative, transitional, and plasmablast cells. RESULTS:We observed a significant variation in terms of frequency and absolute counts between all groups analysed. Values from each B cell subpopulation show variations according to age. CONCLUSIONS:In order to attempt to elucidate reference values for B cell subpopulation, the present study evaluated a population sample of healthy blood donors from this region. Values reported here can also be used as a tool for diagnosis of diseases in which B cell maturation is affected.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Berrón-Ruíz L,López-Herrera G,Ávalos-Martínez CE,Valenzuela-Ponce C,Ramírez-SanJuan E,Santoyo-Sánchez G,Mújica Guzmán F,Espinosa-Rosales FJ,Santos-Argumedo Ldoi
10.1016/j.aller.2016.05.003subject
Has Abstractpub_date
2016-01-01 00:00:00pages
571-579issue
6eissn
0301-0546issn
1578-1267pii
S0301-0546(16)30094-5journal_volume
44pub_type
杂志文章abstract:OBJECTIVE:Exhaled breath condensate (EBC) is a completely non-invasive method for the collection of airway secretions to measure intense inflammation in the airways of asthmatics. It has been shown that the childhood asthma control test (c-ACT) is a good tool for use in the evaluation of asthmatics. Whether the c-ACT s...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2012.09.003
更新日期:2014-05-01 00:00:00
abstract::A short summary of the literature about the cytotoxic leucocyte test was presented. The results of 1824 CLTs involving 23 food allergens were analyzed. Of the foods tested malt, orange, rye, milk, corn, tomato, oats, wheat, brewers yeast and rice were the ten foods giving a reaction most often in the CLT. Except for m...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
abstract::In 1975, Miller and Nussenzweig described a new function of the Complement (C'): the Capacity of this substance to solubilize "in vitro" antigen/antibody complexes previously formed. Subsequent studies of these authors and other researches (particularly Takahashi and his group) demonstrated that this process is mediat...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:
更新日期:1994-09-01 00:00:00
abstract:INTRODUCTION:Chronic granulomatous disease (CGD) is an uncommon primary immune deficiency (affecting 1/200,000 newborn infants) caused by a defect in phagocyte production of oxygen metabolites, and resulting in bacterial infections produced by catalase-positive microorganisms and fungal diseases that occasionally may p...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1157/13106774
更新日期:2007-05-01 00:00:00
abstract::An epidemiological study was performed in the students of Hacettepe University from various parts of Turkey to find the prevalence of asthma and allergic diseases and search for geographical differences in Turkey. A questionnaire related with symptoms of asthma and allergic diseases was distributed to 4600 students an...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Egg is the most frequent cause of food allergy in children. The bird-egg syndrome, found in a group of patients sensitized to egg through bird proteins, was infrequent in children. We report a patient with former history of hypersensitivity to egg who developed episodes of angioedema after ingestion of hen m...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(03)79164-2
更新日期:2003-01-01 00:00:00
abstract::Common variable immunodeficiency is a disorder characterised by hypogammaglobulinemia with B-lymphocytes in peripheral blood and repeated infections. We report a child with a diagnosis of diabetes mellitus and celiac disease during lactation, and in whom common variable immunodeficiency was diagnosed at the age of 5. ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Associations between liver function and serum IgE levels have recently been observed in children. However, the relationship in adults is unclear. Therefore, it was aimed to study associations of liver function and serum total and food-specific IgE concentrations in a national and population-based study. MET...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2014.02.009
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Inhaled corticosteroids are used to treat infants with troublesome asthma-like symptoms but their effect on the lung function of these young patients is controversial. MATERIAL AND METHODS:Forty-four infants with recurrent wheezing (more than 3 episodes) and family history of asthma completed this randomise...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,随机对照试验
doi:10.1016/s0301-0546(09)71105-x
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Lung involvement in rheumatologic disease in children has been described with low frequency. OBJECTIVE:To describe the lung function test and the radiological findings in a group of paediatric patients with rheumatologic diseases. METHODS:Descriptive study. Pulmonary function was evaluated with spirometry,...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2011.02.009
更新日期:2012-03-01 00:00:00
abstract::The aminoacid contents of native chestnut and its powdered form were studied. It was found that it has low cystine and methionine contents but if it is supplemented accordingly, the chestnut pulp can well be used for infant feeding. More than 50 infants were fed with chestnuts, and only in two cases was there intolera...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract::Carboplatin (CP) hypersensitivity reactions have been reported in nearly 12 % of patients treated with this drug. The pathophysiologic mechanisms of these reactions have not been entirely elucidated. Various hypotheses are under discussion. CP hypersensitivity reactions could be IgE-mediated, caused by low-molecular p...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(03)79209-x
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Epidemiological evidence suggests the existence of a direct link between allergic rhinitis (AR) and asthma. Several studies also support the presence of small-airway dysfunction (SAD) in non-asthmatic children with AR. However, it remains unknown whether SAD can predict the progression of AR to asthma. Our o...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2017.09.025
更新日期:2018-01-01 00:00:00
abstract::This study investigated the specificity and efficacy of immunotherapy with Artemisia vulgaris (Artemisia) extract. We studied 25 patients with a more than two year lasting history of seasonal rhinoconjunctivitis and who had only two clinically important allergies, either to Artemisia and Betula verrucosa (Betula) or t...
journal_title:Allergologia et immunopathologia
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:Macrolides are useful in a wide range of bacterial infections including upper and lower respiratory tract, skin, and sexually transmitted diseases and are used in Helicobacter pylori eradication regimen. Skin symptoms occurring during drug therapy are mostly attributed to the antibiotic, causing considerable...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2010.06.008
更新日期:2011-07-01 00:00:00
abstract::Leguminous are a cheap source of protein that are cultivated practically throughout the world. They are the main source of food in developing countries. In the Mediterranean area and Middle East, the most commonly consumed legumes are lentils and chickpea. In the United States, United Kingdom and south-east Asia, the ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/s0301-0546(02)79152-0
更新日期:2002-11-01 00:00:00
abstract::Immunotherapy delivered a new therapeutic option to the oncologist: Ipilimumab (anti-CTLA-4), Nivolumab and Pembrolizumab (anti-PD1), and Atezolizumab (anti-PD-L1) increase overall survival and show a better safety profile compared to chemotherapy in patients with metastatic melanoma, lung, renal cancer among others. ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/j.aller.2018.04.005
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Disseminated BCG infections among other complications of Bacillus Calmette-Guérin (BCG) vaccine are rare and have occurred in children with immunodeficiency disorders such as mendelian susceptibility to mycobacterial disease (MSMD) which could be due to defects in some elements of IL-12/IFN-γ axis. MSMD-ca...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2018.06.005
更新日期:2019-01-01 00:00:00
abstract::Hypersensitivity reactions to aspirin and other NSAIDs occur in individuals genetically predisposed and exhibit different clinical manifestations, especially respiratory, cutaneous, and generalised. Five different phenotypes define distinct clinical pictures: aspirin-exacerbated respiratory disease, aspirin/NSAID cuta...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/j.aller.2016.08.010
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Clinical research has shown that sublingual immunotherapy (SLIT) is effective and safe in moderate-severe allergic rhinitis (AR) induced by house dust mite (HDM). However, the sample size in many studies is small. Meanwhile, the controversy on the efficacy and safety in the very young children younger than f...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2016.10.016
更新日期:2017-01-01 00:00:00
abstract::The spore concentrations of Alternaria, a genera of microfungi widely considered as allergenic by different authors (Caplin & Haynes, Gravesen, Gregory, Larsen, Petersen & Sandberg), have been investigated in the atmosphere of Córdoba (Spain) during the period of April, 1983 to March, 1985 by means of the volumetric (...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1986-03-01 00:00:00
abstract:BACKGROUND:Some studies indicate some causal relationship between obesity and asthma, while others show inconsistent results. Our objective was to evaluate the prevalence of asthma according to obesity in children. METHODS:A cross-sectional study, following the ISAAC study methodology, was conducted on two randomly se...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.aller.2012.05.011
更新日期:2013-05-01 00:00:00
abstract::Five patients with atopic dermatitis, three males and two females, aged 2 to 17 years, had positive reactions to air allergens (Dermatophagoides pteronyssinus and/or farinae). All the patients suffered from severe recurrent dermatophytosis that responded poorly to antifungal treatment. The results of immunologic evalu...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(02)79135-0
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:The objective of this study was to evaluate safety and efficacy of Privigen®, a 10% intravenous immunoglobulin (IVIG), in a particular group of paediatric patients (highly sensitive to previous IVIG infusion) affected with Primary Immunodeficiencies (PID). MATERIAL AND METHODS:Patients (n=8) from 3 to 17 ye...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2012.10.006
更新日期:2014-03-01 00:00:00
abstract::Patients affected by cutinegative, RAST negative, chronic hyperreactive rhinitis showed in 15/28 cases positive intradermal tests, nasal provocation test and RAST on nasal fluids. In 13/28 cases high IgE on nasal samples could be observed and seldom were the intradermal tests positive, but in no case were the nasal pr...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Autosomal dominant hyper-IgE syndrome (AD-HIES) is a primary immunodeficiency mainly caused by mutations in STAT3, a signalling molecule implicated in the development of appropriate immune responses. We aimed to characterise the innate immune response in AD-HIES. METHODS:The frequency of innate immune cells...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2014.11.002
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Children with IgE-mediated cow's milk allergy (IgE-CMA) often tolerate baked milk within a wheat matrix. In our study we evaluated the impact of wheat matrix and of little standardised cooking procedures on tolerance of baked milk. We also tested tolerance versus parmigiano reggiano (PR) and whey-based parti...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2016.03.005
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Angiotensin Converting Enzyme inhibitors (ACEi) may cause angioedema, with an incidence of 0.1 % to 1 %, which may be life-threatening. ACEi induce angioedema by increasing the levels of bradykinin. Angiotensin II receptor blockers (ATRB), have a pharmacological profile similar to ACEi. The polymorphism of t...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Atopic dermatitis (AD) is most common in the first year of life. The aim of this study was to determine the prevalence of and risk factors for AD in a birth cohort of infants from southeast Turkey. METHODS:Adana Paediatric Allergy Research (ADAPAR) birth cohort study was derived from 1377 infants who were b...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2015.07.002
更新日期:2016-05-01 00:00:00
abstract::An experimental model was devised in which an AKR lymphoma is conditioned to grow in BALB mice leading to reproducible tumor incidence which makes tumor-bearing (progressor) and tumor-rejecting (regressor) animals simultaneously available. The object of this paper was to determine the effect of neonatal thymectomy (xT...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1978-09-01 00:00:00