abstract：:Over the past three decades, the number of obese people has risen steadily. The chronic low-grade inflammatory state and the non-specific activation of the immune system have contributed greatly to the development of obesity-related immunology. Food allergy as a kind of inflammatory disease with abnormal immune respon...

journal_title：Allergologia et immunopathologia

authors： Guo X,Cheng L,Yang S,Che H

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Considering the possible roles of interleukin-23 receptor (IL-23R) gene in the pathogenesis of juvenile systemic lupus erythematosus (JSLE), the objective of this study was to elucidate whether polymorphisms of the IL23R are associated with susceptibility to JSLE in an Iranian population. M...

journal_title：Allergologia et immunopathologia

authors： Rezaei A,Harsini S,Sadr M,Ziaee V,Rezaei N

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Due to the high prevalence of recurrent wheezing in the pediatric population, it is important to be able to identify environmental risk factors that may affect the etiology of asthma in several regions. OBJECTIVE:to identify possible risk factors associated with asthma in children (9-12 years old) in Passo ...

journal_title：Allergologia et immunopathologia

authors： Neto ACP,Solé D,Hirakata V,Schmid LS,Klock C,Barreto SSM

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Despite the recommendation against routine use of inhaled bronchodilators in infants with viral bronchiolitis given in the main clinical practice guidelines (CPGs) on viral bronchiolitis, albuterol is widely prescribed to patients with this disease. The aim of this study was to identify pred...

journal_title：Allergologia et immunopathologia

authors： Piña-Hincapie SM,Sossa-Briceño MP,Rodriguez-Martinez CE

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Methemoglobinemia has been reported to be associated with severe food protein-induced enterocolitis syndrome (FPIES). However, no reports have evaluated methemoglobin (MHb) levels in FPIES without symptomatic methemoglobinemia or the usefulness of MHb measurement for the diagnostic predictio...

journal_title：Allergologia et immunopathologia

authors： Makita E,Kuroda S,Sato H,Itabashi K,Kawano A,Matsuura M,Sugiyama Y,Sugawara D,Maruyama A,Ichihashi K

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Anaphylaxis is a sudden, severe, and potentially life-threatening allergic reaction, affecting a portion of allergic patients. Adrenaline is the first-line medication for anaphylaxis and available in many parts of the world as adrenaline autoinjectors (AAIs). OBJECTIVE:Aim of this study was to determine att...

journal_title：Allergologia et immunopathologia

authors： Esenboga S,Ocak M,Cetinkaya PG,Sahiner UM,Soyer O,Buyuktiryaki B,Sekerel BE

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:This study aimed to assess the regular use of long-term asthma-control medication and to determine inhaler techniques in asthmatic children. METHODS:The study was conducted on asthmatic children aged 6-18 years. Information on rescue and controller medications was given and the proper inhalation technique wa...

journal_title：Allergologia et immunopathologia

authors： Can C,Akkelle E,Gökmirza Özdemir P,Yazıcıoğlu M,Süt N

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Allergy to cow's milk proteins has often been associated with dysfunction of the intestinal mucosa caused by chronic inflammation in infants. This study evaluated the protective effect of taurine on intestinal damage induced by beta-lactoglobulin (β-Lg) in Balb/c mice used as an animal model of allergy to co...

journal_title：Allergologia et immunopathologia

authors： Aïnad-Tabet S,Grar H,Haddi A,Negaoui H,Guermat A,Kheroua O,Saïdi D

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The prevalence of food allergy is on the rise on a global scale. OBJECTIVE:To determine the prevalence of food hypersensitivity (FHS) and probable food allergy (PFA), as well as the foods and factors associated with these occurrences. METHODS:A cross-sectional study was carried out among 1992 adolescents (...

journal_title：Allergologia et immunopathologia

authors： Bedolla-Pulido TR,Bedolla-Barajas M,Morales-Romero J,Bedolla-Pulido TI,Domínguez-García MV,Hernández-Colín DD,Flores-Merino MV

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Atopic dermatitis is common among children of 0-5 years old. Treatment consists of emollients and topical corticosteroids. Due to corticophobia, however, adherence to topical corticosteroids is low. Our aim was to find factors that influence opinions about topical corticosteroids among paren...

journal_title：Allergologia et immunopathologia

authors： Veenje S,Osinga H,Antonescu I,Bos B,de Vries TW

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To describe potential regional variations in therapies for severe asthma exacerbations in Chilean children and estimate the associated health expenditures. METHODS:Observational prospective cohort study in 14 hospitals over a one-year period. Children five years of age or older were eligible for inclusion. D...

journal_title：Allergologia et immunopathologia

authors： Herrera AM,Brand P,Cavada G,Koppmann A,Rivas M,Mackenney J,Sepúlveda H,Wevar ME,Cruzat L,Soto S,Pérez MA,León A,Contreras I,Alvarez C,Walker B,Flores C,Lezana V,Garrido C,Herrera ME,Rojas A,Andrades C,Chala E,

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:It is considered that farm areas protect young patients from allergy and asthma due to high exposure to endotoxins. AIM:To compare CD4+/CD25+ T-regulatory cells and forkhead transcription factor Foxp3 expression in asthmatic children allergic to house dust mites (HDM) living in rural and farm areas. MATERI...

journal_title：Allergologia et immunopathologia

authors： Fuss P,Bal K,Jerzyńska J,Podlecka D,Stelmach W,Stelmach I

更新日期：2019-01-01 00:00:00

abstract：AIM:To prospectively evaluate interferences between viruses of the upper respiratory tract in asymptomatic preschool children. METHODS:Nasal-pharyngeal swabs from 233 preschool aged children were prospectively collected over four consecutive time periods, during one school year. The samples were tested using a RT-PCR ...

journal_title：Allergologia et immunopathologia

authors： Douros K,Kotzia D,Kottaridi C,Giotas A,Boutopoulou B,Bozas E,Matziou V,Priftis K,Papaevangelou V

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis is a common illness in childhood. Children with atopic dermatitis are prone to develop cutaneous sensitization due to skin barrier dysfunction. AIM:The aim of this study was to evaluate the frequency of cutaneous sensitizations in patients with atopic dermatitis and to identify the most fr...

journal_title：Allergologia et immunopathologia

authors： Ozceker D,Haslak F,Dilek F,Sipahi S,Yucel E,Guler N,Tamay Z

更新日期：2019-01-01 00:00:00

abstract：:Immunotherapy delivered a new therapeutic option to the oncologist: Ipilimumab (anti-CTLA-4), Nivolumab and Pembrolizumab (anti-PD1), and Atezolizumab (anti-PD-L1) increase overall survival and show a better safety profile compared to chemotherapy in patients with metastatic melanoma, lung, renal cancer among others. ...

journal_title：Allergologia et immunopathologia

authors： Miranda Poma J,Ostios Garcia L,Villamayor Sanchez J,D'errico G

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:The reproducibility of the adverse reaction increases the suggestiveness of a history of food allergy. However, the positive predictive value (PPV) of multiple adverse reaction episodes for the diagnosis of IgE-mediated food allergy is not known. This evaluation was the objective of our stud...

journal_title：Allergologia et immunopathologia

authors： Miceli Sopo S,Gurnari G,Monaco S,Romano A,Liotti L,Cuomo B,Dello Iacono I,Badina L,Longo G,Calvani M,Giannone A,Calabrò C,Scala G,Verga MC

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Disseminated BCG infections among other complications of Bacillus Calmette-Guérin (BCG) vaccine are rare and have occurred in children with immunodeficiency disorders such as mendelian susceptibility to mycobacterial disease (MSMD) which could be due to defects in some elements of IL-12/IFN-γ axis. MSMD-ca...

journal_title：Allergologia et immunopathologia

authors： Pourakbari B,Hosseinpour Sadeghi R,Mahmoudi S,Parvaneh N,Keshavarz Valian S,Mamishi S

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Vitamin D plays a role in the immune system, however studies regarding this are scarce. This study aimed to evaluate the nutritional status of vitamin D in patients with Common Variable Immunodeficiency (CVID) or Ataxia-Telangiectasia (A-T) and to relate it to body composition, inflammatory ...

journal_title：Allergologia et immunopathologia

authors： Cruz JRS,Silva R,Andrade IGA,Fonseca FLA,Costa-Carvalho BT,Sarni ROS

更新日期：2019-01-01 00:00:00

abstract：:Atopic dermatitis (AD) is a multifaceted disease that involves a complex interplay between the skin and the immune system. The course of the disease depends strongly on the genetic background of the patient and on yet poorly-defined environmental factors. Changes in lifestyle could be behind the dramatic rise in the p...

journal_title：Allergologia et immunopathologia

authors： Serra-Baldrich E,de Frutos JO,Jáuregui I,Armario-Hita JC,Silvestre JF,Herraez L,Martín-Santiago A,Valero A,Sastre J

更新日期：2018-01-01 00:00:00

abstract：:Scabies is observed with relatively high frequency in Allergy and Dermatology clinics in developing countries where poor sanitary conditions are prevalent and increasingly in some areas of the world with increased immigrant populations. Since the immunological response to scabies mites includes the production of IgE c...

journal_title：Allergologia et immunopathologia

authors： Sánchez-Borges M,González-Aveledo L,Capriles-Hulett A,Caballero-Fonseca F

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Food allergy can have a major impact on quality of life of children and their parents. Questionnaires have been developed to measure the impact of this disorder. We aimed to validate the EuroPrevall questionnaire on Food Allergy-Quality of Life Questionnaire, Parent Form (FAQLQ-PF) and the Food Allergy Indep...

journal_title：Allergologia et immunopathologia

authors： Bartoll E,Nieto M,Selva B,Badillo R,Pereira G,Uixera S,Nieto A,Mazón Á

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Adherence to pharmacotherapy reduces symptoms of asthma and rhinitis, however, little is known of its impact on school performance. OBJECTIVE:To evaluate the impact of pharmacotherapy in absenteeism and school performance in a child population. METHODS:A cross-sectional study, carried out in eight schools....

journal_title：Allergologia et immunopathologia

authors： Sánchez J,Sánchez A,Cardona R

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Asthma hospitalization rates in Chilean children have increased in the last 14 years, but little is known about the factors associated with this. OBJECTIVE:Describe clinical characteristics of children hospitalized for asthma exacerbation. METHODS:Observational prospective cohort study in 14 hospitals. Ove...

journal_title：Allergologia et immunopathologia

authors： Herrera AM,Brand P,Cavada G,Koppmann A,Rivas M,Mackenney J,Sepúlveda H,Wevar ME,Cruzat L,Soto S,Pérez MA,León A,Contreras I,Alvarez C,Walker B,Flores C,Lezana V,Garrido C,Herrera ME,Rojas A,Andrades C,Chala E,

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Epidemiological evidence suggests the existence of a direct link between allergic rhinitis (AR) and asthma. Several studies also support the presence of small-airway dysfunction (SAD) in non-asthmatic children with AR. However, it remains unknown whether SAD can predict the progression of AR to asthma. Our o...

journal_title：Allergologia et immunopathologia

authors： Skylogianni E,Triga M,Douros K,Bolis K,Priftis KN,Fouzas S,Anthracopoulos MB

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The objective was to estimate the incidence of asthma in young adults from 13-15 years old to 23-25 years old, and associated factors. METHODS:In 2012, a population-based prospective cohort study was carried out in Castellon from the cohort who had participated in the International Study of Asthma and Aller...

journal_title：Allergologia et immunopathologia

authors： Segura-Navas L,Arnedo-Pena A,Tosca-Segura R,Romeu-García MA,Meseguer-Ferrer N,Silvestre-Silvestre E,Conde F,Fernández-González S,Dubon M,Ortuño-Forcada M,Fabregat-Puerto J,Fenollosa-Amposta C,Pac-Sa MR,Museros-Recatala L,Vizc

更新日期：2018-01-01 00:00:00

abstract：:Proteolytic activity is fundamental to survival, so it is not surprising that all living organisms have proteases, especially seine protease. This enzyme in its numerous isoforms and homologues, constitutes the quintessential offence and defence factors, in the form of surface proteins, secreted molecules, gut digesti...

journal_title：Allergologia et immunopathologia

authors： Patel S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Clinical research has shown that sublingual immunotherapy (SLIT) is effective and safe in moderate-severe allergic rhinitis (AR) induced by house dust mite (HDM). However, the sample size in many studies is small. Meanwhile, the controversy on the efficacy and safety in the very young children younger than f...

journal_title：Allergologia et immunopathologia

authors： Lin X,Lin H,Wei X,Huang Q

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Diagnosing asthma in children is a challenge and using a single biomarker from exhaled breath condensate (EBC) showed the lack of improvement in it. OBJECTIVE:The aim of this study was to assess the diagnostic potential of a pattern of simple chemical biomarkers from EBC in diagnosing asthma in children in ...

journal_title：Allergologia et immunopathologia

authors： Maloča Vuljanko I,Turkalj M,Nogalo B,Bulat Lokas S,Plavec D

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:In recent years, traditional diets enriched with fresh plant-based foods have been gradually abandoned, increasing the consumption of animal foods and highly processed food. The aim of this study was to assess the effects of a nutritional intervention with a Traditional Mediterranean Diet in patients with ...

journal_title：Allergologia et immunopathologia

authors： Calatayud FM,Calatayud B,Gallego JG,González-Martín C,Alguacil LF

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) has been associated with impairment of sleep. The aim of this study was to evaluate sleep disorders in AD Latin-American children (4-10 years) from nine countries, and in normal controls (C). METHODS:Parents from 454 C and 340 AD children from referral clinics answered the Children Sl...

journal_title：Allergologia et immunopathologia

authors： Urrutia-Pereira M,Solé D,Rosario NA,Neto HJC,Acosta V,Almendarez CF,Avalos MM,Badellino H,Berroa F,Álvarez-Castelló M,Castillo AJ,Castro-Almarales RL,De la Cruz MM,Cepeda AM,Fernandez C,González-León M,Lozano-Saenz J,Sa

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Although studies have reported an association between air pollutants and increased allergic airway diseases, such as allergic rhinitis and nasal polyposis, the underlying mechanisms are not fully understood. A limited number of studies have suggested that diesel exhaust particles (DEP) play a role in atopy a...

journal_title：Allergologia et immunopathologia

authors： Ozturk AB,Bayraktar R,Gogebakan B,Mumbuc S,Bayram H

更新日期：2017-01-01 00:00:00

abstract：:The system that protects body from infectious agents is immune system. On occasions, the system seldom reacts with some foreign particles and causes allergy. Allergies of the ear, nose and throat (ENT) often have serious consequences, including impairment and emotional strain that lowers the quality of life of patient...

journal_title：Allergologia et immunopathologia

authors： Gupta D,Deshmukh L,Gupta R,Sandhu SS

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Few data are available concerning the time trends and risk factors associated with allergic rhinitis (AR) in schoolchildren in Hungary. METHODS:At an interval of six years, parents of 6-12-year-old children completed identical ISAAC-based and additional questionnaires related to possible risk factors. RESU...

journal_title：Allergologia et immunopathologia

authors： Sultész M,Balogh I,Katona G,Mezei G,Hirschberg A,Gálffy G

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE/HYPOTHESIS:We systematically reviewed the associations between allergic rhinitis or allergy and otitis media with effusion, by reference to published data. STUDY DESIGN:A meta-analysis of case-controlled studies. DATA SOURCE:Five databases (Pubmed, Highwire, Medline, Wanfang, and China National Knowledge In...

journal_title：Allergologia et immunopathologia

authors： Cheng X,Sheng H,Ma R,Gao Z,Han Z,Chi F,Cong N,Wang J,Liu X,Luo X,Yu J,Ra Y

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether the genetic variants of TGFB1, TLE4, MUC22 and IKZF3 are associated with the development of asthma in Chinese children. METHODS:572 adolescent asthma patients and 590 age-matched healthy controls were included in this study. A total of four SNPs were genotyped, including rs2241715 of T...

journal_title：Allergologia et immunopathologia

authors： Chen JB,Zhang J,Hu HZ,Xue M,Jin YJ

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Despite growing evidence suggesting potential association between innate and adaptive immunity in viral-induced acute asthma, there is paucity of data in this area. OBJECTIVE:This study aimed to investigate the association of innate and adaptive immunity with acute asthma attacks by analysing the role of IF...

journal_title：Allergologia et immunopathologia

authors： Arikoglu T,Akyilmaz E,Yildirim DD,Batmaz SB,Ulger ST,Aslan G,Kuyucu S

更新日期：2017-01-01 00:00:00

abstract：:Hypersensitivity reactions to aspirin and other NSAIDs occur in individuals genetically predisposed and exhibit different clinical manifestations, especially respiratory, cutaneous, and generalised. Five different phenotypes define distinct clinical pictures: aspirin-exacerbated respiratory disease, aspirin/NSAID cuta...

journal_title：Allergologia et immunopathologia

authors： Sánchez-Borges M,Caballero-Fonseca F,Capriles-Hulett A

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:It is thought that airway inflammation is more common in obese asthmatic patients because inflammation is harder to control and does not respond well to glucocorticoid treatment. OBJECTIVE:This study's aim was to investigate the effect of obesity on airway and systemic inflammation in children with asthma a...

journal_title：Allergologia et immunopathologia

authors： Nacaroglu HT,Gayret OB,Erol M,Buke O,Zengi O,Tasdemir M,Tasdemir Z,Yigit O

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:House dust mites are a ubiquitous air allergen in the human habitat. It has been shown that exposure to them is a fundamental factor in sensitisation and development of atopic disease. The objective of the study was to analyse changes in sensitisation to Dermatophagoides pteronyssinus (Der p.) in children tr...

journal_title：Allergologia et immunopathologia

authors： Navarrete-Rodríguez EM,Fernández-Soto JR,Del Rio-Navarro BE,Saucedo-Ramírez OJ,Sienra-Monge JJ

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that serum interleukin 33 serving as an "alarmin" is increased in children with asthma. The objective of this study was to assess the validity of serum IL33 test for early diagnosis of childhood asthma. METHODS:A literature search was performed in June 2016 using PubMed, Embase, ...

journal_title：Allergologia et immunopathologia

authors： Wang Y,Wang L,Hua S

更新日期：2017-01-01 00:00:00