Atopic dermatitis with mononuclear phagocytic activity deficiency.

Abstract:

:Five patients with atopic dermatitis, three males and two females, aged 2 to 17 years, had positive reactions to air allergens (Dermatophagoides pteronyssinus and/or farinae). All the patients suffered from severe recurrent dermatophytosis that responded poorly to antifungal treatment. The results of immunologic evaluation by laboratory tests were normal, except for a decrease in the ingestion phase by mononuclear phagocytes. After diagnosis of immunodeficiency, ketoconazole shampoo was used prophylactically and at the very first signs of recurrence of dermatophytosis, systemic antifungal treatment was started, without concurrent use of macrolides and with monitoring of hepatic function. The fungal infections responded well to this treatment and the patients' quality of life markedly improved.

authors

Forte WC,Santos de Menezes MC,Cipolli Guerra de Oliveira SM,Bruno S

doi

10.1016/s0301-0546(02)79135-0

keywords:

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

263-6

issue

5

eissn

0301-0546

issn

1578-1267

pii

13038904

journal_volume

30

pub_type

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