Oral rush desensitization to cow milk. Following of desensitized patients during three years.

Abstract:

:We report the induction of tolerance in four patients with severe IgE-mediated cow's milk allergy, with an oral rush desensitization by introducing increasing daily doses of cow's milk (CM) for 5 days under clinical conditions in order to enable the patients to tolerate 200 ml of CM daily. Our results indicate that we can induce clinical tolerance in CM allergy by oral administration of progressive doses of milk. After three years of following, the four patients are taking CM with good tolerance. Specific IgE levels of casein have decreased progressively during these three years until being not detectable in three of the four patients and also a reduction has been observed in the cutaneous skin prick test reactions to CM.

authors

Martorell Aragonés A,Félix Toledo R,Cerdá Mir JC,Martorell Calatayud A

doi

10.1157/13110311

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

174-6

issue

5

eissn

0301-0546

issn

1578-1267

pii

13110311

journal_volume

35

pub_type

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