Abstract:
:A 25 year old, 70 kg female chimpanzee had a 12 year history of intermittent signs of upper respiratory tract allergic disease. In June 1987, she was given Terfenadinea, 60 mg b.i.d., with excellent resolution of symptoms. During her annual physical examination, while maintained under ketamine anesthesia, the chimp was skin tested intradermally for respiratory allergies prevalent in the Sacramento area, and blood was drawn for "in vitro" evaluation. Strong positive skin reactions were obtained against grass, weed and tree antigens mixes, with little reaction to mold and mite allergens. Pollen specific IgG4 levels, as measured by fluorescence allergosorbent test (FAST)b, were elevated, and these data are discussed. The serum IgE results corresponded closely with traditional intradermal skin tests, suggesting the application of the human test (FAST)b to the chimpanzee, and potentially other nonhuman primates. The specificity, convenience, absence of risk of serum testing make it an attractive alternative to intradermal skin tests in nonhuman primates.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Halpern GM,Gershwin LJ,Gonzales G,Fowler MEsubject
Has Abstractpub_date
1989-09-01 00:00:00pages
271-6issue
5eissn
0301-0546issn
1578-1267journal_volume
17pub_type
杂志文章abstract::Shellfish is one of the most frequent causes of food allergy. We studied 48 patients (25 male and 23 female) with a mean age of 24.2 +/- 1.8 with shellfish hypersensitivity. A clinical questionnaire was carried out and prick tests were performed using a series of aeroallergens and a battery of extracts of squid, shrim...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:
更新日期:1994-03-01 00:00:00
abstract::Numerous reports had been published implicating IPPD and other amine-type antioxidants as the causative agents in patients with allergic sensitization following the use of industrial and household products that have black rubber in their composition. The amine-type antioxidants, used to stabilize the polymer chains an...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::In normal individuals the 5/9 monoclonal antibody (5/9 MAb) recognizes a T-cell fraction that includes all T lymphocytes with inducer activities. Here, circulating 5/9+ and 5/9- T lymphocytes were isolated from tuberculim skin-positive subjects and the proliferative response induced by PPD was investigated. The result...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::A study on the presence of specific precipitins against tobacco antigens was done in a population of 361 healthy cigrette smokers and in a group of 60 healthy non-smokers. The tests were made by the gel diffusion technique of Ouchterlony using tobacco extract prepared by the Coca method. A positive precipitation react...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1977-11-01 00:00:00
abstract::The gaseous phase cultures of alveolar macrophages (AMs) of guinea pig were exposed to the saline extracts of the dust-borne bacteria Micropolyspora faeni (syn. Faenia rectivirgula) and Erwinia herbicola (syn. Enterobacter agglomerans) which have been added at the concentration of 1 microgram/ml to culture medium with...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract:BACKGROUND:The relationship between GERD and asthma is complex. It is not yet clear whether GERD is an accompanying finding or a cause of asthma, or even if it is an aggravating factor. The aim of this study was to determine the frequency of asthma and allergic diseases in patients who underwent 24-h pH monitoring for ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2012.08.009
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:Disseminated BCG infections among other complications of Bacillus Calmette-Guérin (BCG) vaccine are rare and have occurred in children with immunodeficiency disorders such as mendelian susceptibility to mycobacterial disease (MSMD) which could be due to defects in some elements of IL-12/IFN-γ axis. MSMD-ca...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2018.06.005
更新日期:2019-01-01 00:00:00
abstract::The aims of this report are: to investigate the kinetics of the E. coli lipopolysaccharide polyclonal response as a function of the background response, to test the capacity of lipopolysaccharide to activate presumably resting memory cells for IgM. Because mice do not produce a plaque-forming cell background against r...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:To assess concordance in the measurement of peak expiratory flow (PEF) and forced expiratory volume ino ne second (FEV(1)) between the portable device Piko-1 (Ferraris) and a pneumotachograph. PATIENTS AND METHODS:Forced spirometry (Master Screen Jaeger) was performed according to ATS/ERS norms, selecting th...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2009.03.004
更新日期:2009-09-01 00:00:00
abstract::Thirteen patients with severe partially reversible chronic obstructive lung disease received long-term treatment with a sustained-release preparation of theophylline and a beta 2-agonist (terbutaline) alone and in combination. Combination therapy induced significantly greater bronchodilation than treatment with terbut...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1985-11-01 00:00:00
abstract::Since the first decades of the twentieth century, some authors have believed bacterial respiratory infection to be an important triggering factor in bronchial asthma, drawing attention to an asthmatic response to infection. In this context, already in 1995, we presented a study on nasal secretion cultures and the rela...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/s0301-0546(01)79035-0
更新日期:2001-05-01 00:00:00
abstract::We report a case of nasal candidiasis in an immunocompetent host who denied the use of topical or systemic corticosteroids. The patient was treated with itraconazole 100 mg. with resolution of the symptoms. ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:Some studies indicate some causal relationship between obesity and asthma, while others show inconsistent results. Our objective was to evaluate the prevalence of asthma according to obesity in children. METHODS:A cross-sectional study, following the ISAAC study methodology, was conducted on two randomly se...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.aller.2012.05.011
更新日期:2013-05-01 00:00:00
abstract::Olea Europaea is the most important allergenic tree in Southern Italy and in the Naples area. Its pollination period lasts from the middle of April to the end of June. In our pollinosis patients we observed frequency of sensitization of 13.05% to Olea pollen. That means that this pollen follows Parietaria (47.80%) and...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1985-05-01 00:00:00
abstract::In a 19 year old patient suffering from CMC since the first months of life, clinical improvement accompanied by correction of the immunologic defect was achieved by Transfer Factor therapy. After 12 months from the last administration of Transfer Factor the improvement persisted. The positive outcome of the treatment ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract:BACKGROUND:Chronic granulomatous disease is a phagocyte defect, characterised by recurrent infections in different organs due to a defect in NADPH oxidase complex. This study was performed to investigate pulmonary problems of CGD in a group of patients who underwent computed tomography (CT) scan. METHODS:Computed tomo...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2013.04.003
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Asthma hospitalization rates in Chilean children have increased in the last 14 years, but little is known about the factors associated with this. OBJECTIVE:Describe clinical characteristics of children hospitalized for asthma exacerbation. METHODS:Observational prospective cohort study in 14 hospitals. Ove...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.aller.2018.02.006
更新日期:2018-01-01 00:00:00
abstract::We report the case of a 51-year-old woman who had an immediate skin reaction after subcutaneous administration of a local anesthetic (LA) composed of articaine and epinephrine before a dental procedure. The patient subsequently underwent further dental procedures without LA. Skin prick tests performed with commercial ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1157/13072924
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:IgE-mediated systemic reactions to local anaesthetics may be seen--although rarely--by dentists. However, it is not known whether dentists are familiar with symptoms, signs and management of anaphylaxis. METHODS:In this study we aimed to evaluate knowledge of dentists of the symptoms and signs and current t...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2010.07.009
更新日期:2011-07-01 00:00:00
abstract::The reactivity of complement (C) with housedust allergen has been investigated in separate groups of sera from atopic patients with seasonal hay fever, bronchial asthma, atopic dermatitis, animal dander allergy or asthmatic bronchitis as compared to controls. Complement consumption was more pronounced on average in th...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::The percentages and absolute numbers of T, B and "null" cells were studied in 100 allergic patients and compared with values observed in 35 healthy age matched control subjects. T cells were identified by their ability to form spontaneous rosettes with SRBC (E-RFC) and B cells by their complement receptor that allows ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract:INTRODUCTION:Chronic granulomatous disease (CGD) is an uncommon primary immune deficiency (affecting 1/200,000 newborn infants) caused by a defect in phagocyte production of oxygen metabolites, and resulting in bacterial infections produced by catalase-positive microorganisms and fungal diseases that occasionally may p...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1157/13106774
更新日期:2007-05-01 00:00:00
abstract::The effect of intra-lymphatic administration of Lipiodol-l131 on the number of T and B lymphocytes, and on the in vivo response to common antigens and to DNCB, was investigated in uremic patients in the pre-transplant period. T lymphocytes have been detected by rosette formation with sheep erythrocytes (E) and B lymph...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
abstract::House dust mites (HDM) are a major cause of allergic sensitization and airway disease. Technological advances in assays permit the measurement of major mite allergens in house dust samples more accurately. We compared the results of different methods in the assessment of exposure to domestic mites in sensitized patien...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract::Atopic dermatitis (AD) is a multifaceted disease that involves a complex interplay between the skin and the immune system. The course of the disease depends strongly on the genetic background of the patient and on yet poorly-defined environmental factors. Changes in lifestyle could be behind the dramatic rise in the p...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/j.aller.2017.07.002
更新日期:2018-01-01 00:00:00
abstract::A retrospective study on 52,900 individuals tested in 177 Italian Medical Centres for AIDS and related syndromes is reported. The data confirm that I.V. drug users are the group at highest risk in Italy (46% were seropositive and more than one half of these presented PGL or ARC) and that the epidemic probably started ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Macrolides are useful in a wide range of bacterial infections including upper and lower respiratory tract, skin, and sexually transmitted diseases and are used in Helicobacter pylori eradication regimen. Skin symptoms occurring during drug therapy are mostly attributed to the antibiotic, causing considerable...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2010.06.008
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Pseudo-allergic reactions against aspirin (ASA) and non-steroidal anti-inflammatory drugs (NSAIDs) are quite frequent. OBJECTIVE:Our aim was to determine tolerance of Celecoxib, a selective inhibitor of cyclooxygenase-2 (Cox-2), by oral challenge test in patients who showed skin reactions (diffuse erythema ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1157/13108222
更新日期:2007-07-01 00:00:00
abstract::Leguminous are a cheap source of protein that are cultivated practically throughout the world. They are the main source of food in developing countries. In the Mediterranean area and Middle East, the most commonly consumed legumes are lentils and chickpea. In the United States, United Kingdom and south-east Asia, the ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/s0301-0546(02)79152-0
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:The inhalation of Parietaria judaica pollen is a common cause of allergic respiratory diseases in the Mediterranean area. The objective of this study was to investigate the safety and clinical efficacy of a chemically modified (depigmented and glutaraldehyde-polymerized) vaccine of Parietaria judaica. METHO...
journal_title:Allergologia et immunopathologia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0301-0546(03)79170-8
更新日期:2003-03-01 00:00:00