The immunological response to tobacco antigens in the smoker. I. Specific precipitins against tobacco antigens in the serum of healthy cigarette smokers.

Abstract:

:A study on the presence of specific precipitins against tobacco antigens was done in a population of 361 healthy cigrette smokers and in a group of 60 healthy non-smokers. The tests were made by the gel diffusion technique of Ouchterlony using tobacco extract prepared by the Coca method. A positive precipitation reaction was observed in 11.8 per cent of the smokers' sera examined but never in the non-smokers group. The reaction occurred in subjects of both sexes and was neither dependent upon how long they had smoked nor on the number of cigarettes smoked daily. In the authors' opinion, the formation of precipitins against tobacco antigens may be the result of a sensitivity reaction. It is therefore possible that in predisposed individuals immune complexes of precipitins and tobacco antigens may be formed. They could be responsible for some cardiovascular disorders occuring in smokers. In order to confirm such a hypothesis, a study was carried out recently by the authors on a large group of patients suffering from coronary disease.

authors

Romanski B,Broda S

subject

Has Abstract

pub_date

1977-11-01 00:00:00

pages

659-62

issue

6

eissn

0301-0546

issn

1578-1267

journal_volume

5

pub_type

杂志文章
  • [Allergic manifestations of systemic lupus erythematosus].

    abstract::Clinical experience suggests that allergic signs and symptoms are more frequently observed in patients with systemic lupus erythematosus than in the general population. The aim of this paper was to evaluate the frequency of allergic clinical manifestations in systemic lupus erythematosus (SLE) by anamnesis. Sixty thre...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Diumenjo MS,Lisanti M,Vallés R,Rivero I

    更新日期:1985-07-01 00:00:00

  • An epidemiological survey of hymenoptera venom allergy in the Spanish paediatric population.

    abstract:UNLABELLED:Hypersensitivity reactions to hymenoptera venom are infrequent in paediatric patients. A study was made to determine the incidence of this pathology in children, based on an epidemiological survey targeted to all members of the SEICAP (Sociedad Española de Inmunología Clínica y Alergia Pediátrica/Spanish Soc...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2010.02.004

    authors: Martínez-Cañavate A,Tabar AI,Eseverri JL,Martín F,Pedemonte-Marco C

    更新日期:2010-09-01 00:00:00

  • Reliability of the prick-test in comparison to other techniques.

    abstract::This paper aims to establish the diagnostic reliability of the Prick test and its correlation to other techniques used in allergologic diagnosis: intracutaneous testing, RAST, hemagglutination, histamine liberation test. All of these tests were realized in 55 patients with bronchial asthma and with marked sensitizatio...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Cavallo A,Oehling A,Sanz ML,Ona J,Subirá ML

    更新日期:1983-01-01 00:00:00

  • Different lymphocyte markers and cytokine expression in peripheral blood mononuclear cells in children with acute atopic dermatitis.

    abstract:BACKGROUND:The pathogenesis of atopic dermatitis (AD) is still not completely understood. AD is characterized by the presence of clinical symptoms of both IgE antibody-mediated immediate hypersensitivity and specific T lymphocyte-mediated delayed hypersensitivity. OBJECTIVE:To evaluate the immunological mechanisms inv...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/s0301-0546(04)79251-4

    authors: Antúnez C,Torres MJ,Corzo JL,Pena RR,Mayorga C,Jurado A,Santamaría-Babi LF,Blanca M

    更新日期:2004-09-01 00:00:00

  • Immunosuppressive effect of intra-lymphatic irradiation.

    abstract::The effect of intra-lymphatic administration of Lipiodol-l131 on the number of T and B lymphocytes, and on the in vivo response to common antigens and to DNCB, was investigated in uremic patients in the pre-transplant period. T lymphocytes have been detected by rosette formation with sheep erythrocytes (E) and B lymph...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Galvão MM,Sabbaga E,Peixinho ZF,Musatti CC,Mendes NF

    更新日期:1975-09-01 00:00:00

  • Disodium-cromoglycate and immune response mechanism.

    abstract::The influence of disodium-cromoglycate on different humoral and cellular immune reactions was examined. When injected intravenously DSCG reduces the formation of specific IgG producing (plaque forming) spleen cells in mice. It reduces also the mitogen induced macrophage migration inhibition in vitro. The same reduced ...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Gillissen G

    更新日期:1982-05-01 00:00:00

  • Concordance between the Piko - 1 portable device and pneumotachography in measuring PEF and FEV(1) in asthmatic children.

    abstract:OBJECTIVE:To assess concordance in the measurement of peak expiratory flow (PEF) and forced expiratory volume ino ne second (FEV(1)) between the portable device Piko-1 (Ferraris) and a pneumotachograph. PATIENTS AND METHODS:Forced spirometry (Master Screen Jaeger) was performed according to ATS/ERS norms, selecting th...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2009.03.004

    authors: Aguilar-Fernández AJ,Villa-Asensi JR,Castro-Codesal M,Almería-Gil E,González-Alvarez MI,Romero-Andújar F

    更新日期:2009-09-01 00:00:00

  • The evaluation of neutrophil-lymphocyte ratio in children with asthma.

    abstract:BACKGROUND:Neutrophil-lymphocyte ratio (NLR) is a test used to evaluate the systemic inflammation. There is little knowledge about the neutrophil-lymphocyte ratio in asthmatics. In our study, we aimed to evaluate NLR and to assess its relationship with clinical parameters in children with asthma. METHODS:Four hundred ...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2015.09.005

    authors: Dogru M,Yesiltepe Mutlu RG

    更新日期:2016-07-01 00:00:00

  • Nasal provocation test (NPT) through previously active rhinomanometry: physical and mathematical reasons.

    abstract::Rhinomanometry is a technique which studies the resistance of the nasal airways. It also permits us to measure their variations during NPT. This work has analysed the different methods of rhinomanometry (previously active, previously passive and late), commenting on its advantages and disadvantages. Bearing in mind th...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Olivé Pérez A

    更新日期:1989-11-01 00:00:00

  • The efficacy and safety of sublingual immunotherapy in children and adult patients with allergic rhinitis.

    abstract:BACKGROUND:Clinical research has shown that sublingual immunotherapy (SLIT) is effective and safe in moderate-severe allergic rhinitis (AR) induced by house dust mite (HDM). However, the sample size in many studies is small. Meanwhile, the controversy on the efficacy and safety in the very young children younger than f...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2016.10.016

    authors: Lin X,Lin H,Wei X,Huang Q

    更新日期:2017-01-01 00:00:00

  • Effects of Mediterranean diet in patients with recurring colds and frequent complications.

    abstract:INTRODUCTION:In recent years, traditional diets enriched with fresh plant-based foods have been gradually abandoned, increasing the consumption of animal foods and highly processed food. The aim of this study was to assess the effects of a nutritional intervention with a Traditional Mediterranean Diet in patients with ...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2016.08.006

    authors: Calatayud FM,Calatayud B,Gallego JG,González-Martín C,Alguacil LF

    更新日期:2017-01-01 00:00:00

  • Major allergen from Amaranthus palmeri pollen is a profilin: Isolation, partial characterisation and IgE recognition.

    abstract:BACKGROUND:Pollens represent a rich source of proteins that are also potential elicitors of IgE-mediated pollen allergy. Sensitisation to panallergens could play an important role in diagnosis and specific immunotherapy, because these molecules are present in different plant pollens and plant foods and have marked stru...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2015.05.002

    authors: Landa-Pineda CM,Arroyo-Becerra A,Rosas-Alvarado A,Terán LM,Garcia-Cruz ML,Marchat LA,Reyes-López CA

    更新日期:2016-03-01 00:00:00

  • HIV-1: absence of infection in subjects with indeterminate western blot.

    abstract::The search for specific antibodies against the Human Immunodeficiency Virus type-1 (Ab anti HIV 1), using an immunoenzymatic test and a subsequent confirmation test (Western Blot-WB) in patients who were previously positive or borderline at the first test, singled out from about 12500 tested subjects, fifteen patients...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Migali E,Mariotti D,Lovari A,Tenani T,Imperiali P,Ozzola G

    更新日期:1993-03-01 00:00:00

  • Polymyxin B-induced basophil degranulation in atopic and non-atopic asthmatic patients.

    abstract::It is suggested that increased reactivity in asthma is not limited to the bronchi but also exists in the mediator releasing system. We have previously observed that the basophils of atopic asthmatics are degranulated by polymyxin B in vitro. The present study attempts to relate this basophil degranulation to atopy. Th...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Górski P

    更新日期:1985-09-01 00:00:00

  • Recurrent wheezing and asthma after bocavirus bronchiolitis.

    abstract:BACKGROUND:Human bocavirus (HBoV) was recently discovered and identified as an important cause of respiratory infection in young children. However, the relationship between HBoV-bronchiolitis and the development of recurrent wheezing has not yet been established. OBJECTIVE:We designed this study in order to describe t...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2015.07.004

    authors: Del Rosal T,García-García ML,Calvo C,Gozalo F,Pozo F,Casas I

    更新日期:2016-09-01 00:00:00

  • Atopic dermatitis with mononuclear phagocytic activity deficiency.

    abstract::Five patients with atopic dermatitis, three males and two females, aged 2 to 17 years, had positive reactions to air allergens (Dermatophagoides pteronyssinus and/or farinae). All the patients suffered from severe recurrent dermatophytosis that responded poorly to antifungal treatment. The results of immunologic evalu...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/s0301-0546(02)79135-0

    authors: Forte WC,Santos de Menezes MC,Cipolli Guerra de Oliveira SM,Bruno S

    更新日期:2002-09-01 00:00:00

  • Assessment of regular drug use and inhaler technique skills in asthmatic children.

    abstract:OBJECTIVE:This study aimed to assess the regular use of long-term asthma-control medication and to determine inhaler techniques in asthmatic children. METHODS:The study was conducted on asthmatic children aged 6-18 years. Information on rescue and controller medications was given and the proper inhalation technique wa...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2019.06.009

    authors: Can C,Akkelle E,Gökmirza Özdemir P,Yazıcıoğlu M,Süt N

    更新日期:2020-01-01 00:00:00

  • Comparison of methemoglobin levels in food protein-induced enterocolitis syndrome and other gastrointestinal diseases in neonates.

    abstract:INTRODUCTION AND OBJECTIVES:Methemoglobinemia has been reported to be associated with severe food protein-induced enterocolitis syndrome (FPIES). However, no reports have evaluated methemoglobin (MHb) levels in FPIES without symptomatic methemoglobinemia or the usefulness of MHb measurement for the diagnostic predictio...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2020.01.007

    authors: Makita E,Kuroda S,Sato H,Itabashi K,Kawano A,Matsuura M,Sugiyama Y,Sugawara D,Maruyama A,Ichihashi K

    更新日期:2020-01-01 00:00:00

  • [Rhinitis with intolerance to non-steroidal anti-inflammatory agents. Report of 3 cases].

    abstract::Lumry described 6 patients who presented hypertrophic rhinosinusitis, positive nasal eosinophilia and intolerance to nonsteroidal antiinflammatory drugs, manifested exclusively with naso-ocular symptomatology. We present three patients with clinical manifestations of chronic rhinitis who had noticed before their first...

    journal_title:Allergologia et immunopathologia

    pub_type: 临床试验,杂志文章

    doi:

    authors: Prieto L,Pastor A,Palop A,Castro J,Paricio A,Piquer A

    更新日期:1986-03-01 00:00:00

  • Association between environmental exposure and CD4+CD25+ regulatory T cells.

    abstract:BACKGROUND:It is considered that farm areas protect young patients from allergy and asthma due to high exposure to endotoxins. AIM:To compare CD4+/CD25+ T-regulatory cells and forkhead transcription factor Foxp3 expression in asthmatic children allergic to house dust mites (HDM) living in rural and farm areas. MATERI...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2018.04.003

    authors: Fuss P,Bal K,Jerzyńska J,Podlecka D,Stelmach W,Stelmach I

    更新日期:2019-01-01 00:00:00

  • Food allergy and child asthma.

    abstract::The etiological importance of the dietary factor as related to infantile bronchial asthma is not, at times, sufficiently taken into consideration. Nevertheless, many times foods or their components are capable of provoking asthmatic symptoms. A group of asthmatic children was studied with the goal of more throughly co...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Oehling A,Baena Cagnani CE

    更新日期:1980-01-01 00:00:00

  • Perception of bronchodilation assessed by Visual Analogue Scale in children with asthma.

    abstract:BACKGROUND:Visual Analogue Scale (VAS) has been proposed as a useful tool for assessing the perception of asthma symptoms, a cornerstone in disease management. While airway flow limitation and its reversibility are thought to be a useful marker of disease severity, there are very few studies that evaluated the response...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2012.06.002

    authors: Tosca MA,Silvestri M,Rossi GA,Ciprandi G

    更新日期:2013-11-01 00:00:00

  • Local humoral immunity in patients with pollen allergy.

    abstract::All classes of immunoglobulins and albumin have been studied in different phases of disease, both in blood and in the nasal secretions of 75 patients with pollen allergy. There were 20 healthy persons in the test group. Total correlational analysis was done to determine interdependence of the researched indexes. The p...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Gurgenidze GV,Baraban EI,Gamkrelidze AG

    更新日期:1990-11-01 00:00:00

  • Reduction in the oral doses of theophylline in asthmatic children during concomitant treatment with ketotifen.

    abstract::Sixteen children with moderate or severe bronchial asthma underwent a double-blind study receiving either ketotifen (K) or placebo (P) in order to verify the sparing effect of K on theophylline. The study lasted 18 weeks. Slow release theophylline was administered to all patients at a dose of 300 mg every 12 hours for...

    journal_title:Allergologia et immunopathologia

    pub_type: 临床试验,杂志文章

    doi:

    authors: Solé D,Mallozi MC,Toledo EC,Passos Soares FJ,Naspitz CK

    更新日期:1992-03-01 00:00:00

  • Value of the peak expiratory flow in bronchodynamic tests.

    abstract:OBJECTIVE:To determine the accuracy of the peak expiratory flow (PEF) as an alternative parameter to the forced expiratory volume at first second (FEV1) in the bronchodynamic tests. METHODOLOGY:We studied 84 patients, 53 males and 31 females, with average age 46 +/- 13 years, as clinic suspects of bronchial asthma. PE...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Pino JM,García-Río F,Prados C,Alvarez-Sala R,Díaz S,Villasante C,Villamor J

    更新日期:1996-03-01 00:00:00

  • Premenstrual asthma and leukotriene variations in the menstrual cycle.

    abstract:BACKGROUND:Several authors have reported an increase in leukotriene C4 in the premenstrual phase in women with severe premenstrual asthma, indicating that antileukotrienes could be used in treatment. OBJECTIVE:To analyse the role of leukotrienes in premenstrual asthma. METHODS:A questionnaire on respiratory symptoms ...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2011.09.007

    authors: Pereira-Vega A,Sánchez Ramos JL,Maldonado Pérez JA,Vázquez Oliva R,Bravo Nieto JM,Vázquez Rico I,Ignacio García JM,Romero Palacios P,Alwakil Olbah M,Medina Gallardo JF

    更新日期:2012-11-01 00:00:00

  • Improved diagnostic procedures in allergic RAST negative rhinitis.

    abstract::Patients affected by cutinegative, RAST negative, chronic hyperreactive rhinitis showed in 15/28 cases positive intradermal tests, nasal provocation test and RAST on nasal fluids. In 13/28 cases high IgE on nasal samples could be observed and seldom were the intradermal tests positive, but in no case were the nasal pr...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:

    authors: Valerio G,Cassano P,Attimonelli R,Salerno FG

    更新日期:1988-01-01 00:00:00

  • Genome-wide association studies (GWAS) and their importance in asthma.

    abstract::Asthma is a complex disease determined by the interaction of different genes and environmental factors. The first genetic investigations in asthma were candidate gene association studies and linkage studies. In recent years research has focused on association studies that scan the entire genome without any prior condi...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章,评审

    doi:10.1016/j.aller.2014.07.004

    authors: García-Sánchez A,Isidoro-García M,García-Solaesa V,Sanz C,Hernández-Hernández L,Padrón-Morales J,Lorente-Toledano F,Dávila I

    更新日期:2015-11-01 00:00:00

  • [Prevention of food allergy].

    abstract::The occurrence of allergic diseases depends on genetic and environmental factors. Genetic factors determine individual risk and these persons should undergo early detection. However, the methods currently available (mainly clinical history and IgE in umbilical cord blood) have poor predictive value so their use in the...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章,评审

    doi:

    authors: Martín Esteban M,Pascual CY,García Ara MC

    更新日期:1998-05-01 00:00:00

  • A 10% liquid immunoglobulin preparation for intravenous use (Privigen®) in paediatric patients with primary immunodeficiencies and hypersensitivity to IVIG.

    abstract:BACKGROUND:The objective of this study was to evaluate safety and efficacy of Privigen®, a 10% intravenous immunoglobulin (IVIG), in a particular group of paediatric patients (highly sensitive to previous IVIG infusion) affected with Primary Immunodeficiencies (PID). MATERIAL AND METHODS:Patients (n=8) from 3 to 17 ye...

    journal_title:Allergologia et immunopathologia

    pub_type: 杂志文章

    doi:10.1016/j.aller.2012.10.006

    authors: Lozano-Blasco J,Martín-Mateos MA,Alsina L,Domínguez O,Giner MT,Piquer M,Alvaro M,Plaza AM

    更新日期:2014-03-01 00:00:00