Abstract：
BACKGROUND:Visual Analogue Scale (VAS) has been proposed as a useful tool for assessing the perception of asthma symptoms, a cornerstone in disease management. While airway flow limitation and its reversibility are thought to be a useful marker of disease severity, there are very few studies that evaluated the response to bronchodilation (BD) testing perception by VAS. To investigate whether VAS assessment of breathlessness perception could provide a useful tool to assess the response to BD testing in asthmatic children. METHODS:This cross-sectional study included a total of 150 children (96 males, mean age 11.05 years) with asthma, 50 had bronchial obstruction (i.e. FEV1 <80% of predicted). Perception of breathlessness was assessed by VAS; lung function was measured by spirometry. BD testing was performed in all children. RESULTS:In children with bronchial obstruction, VAS at baseline was 4.7 and significantly increased to 6.9 (p<0.001) after BD. In children without bronchial obstruction, VAS at baseline was 7.4, but further significantly increased to 8.4 after BD testing (p<0.01). There was a significant difference in Δ VAS between children with bronchial reversibility and children without it (p<0.0001). CONCLUSIONS:The present study demonstrates that VAS might be considered an initial tool to assess the BD response in children with asthma, mainly with overt bronchial obstruction.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Tosca MA,Silvestri M,Rossi GA,Ciprandi Gdoi
10.1016/j.aller.2012.06.002subject
Has Abstractpub_date
2013-11-01 00:00:00pages
359-63issue
6eissn
0301-0546issn
1578-1267pii
S0301-0546(12)00212-1journal_volume
41pub_type
杂志文章abstract：:We report the case of a 42-year-old non-smoking man, who had worked as a carpenter for 6 years and who reported a history of rhinorrhea, paroxysmal sneezing, nasocular pruritus, lacrimation, wheezing and dyspnea attacks while preparing a mixture to seal the junctures between wooden panels. Allergy study consisted of s...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(05)73251-1
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND:The objective of this study was to examine the B lymphocyte subsets in primary immunodeficiency that progress with antibody deficiency. METHODS:The patients' naive, memory, class-switched memory and non-switched memory B cells were compared with those of healthy individuals of matching ages using flow cytom...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.11.003
更新日期：2016-07-01 00:00:00
abstract：:Propranolol (PRO) is a beta-adrenergic receptor antagonist. The studies were aimed to evaluate the effect of a single intravenous PRO injection at a dose of 0.1 mg/kg on some immune parameters, and were performed on 12 men, including 9 duodenal ulcer patients and 3 healthy subjects, aged 19-23 years (mean 20.5 +/- 1.2...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
abstract：:Clinical experience suggests that allergic signs and symptoms are more frequently observed in patients with systemic lupus erythematosus than in the general population. The aim of this paper was to evaluate the frequency of allergic clinical manifestations in systemic lupus erythematosus (SLE) by anamnesis. Sixty thre...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-07-01 00:00:00
abstract：:The spore concentrations of Alternaria, a genera of microfungi widely considered as allergenic by different authors (Caplin & Haynes, Gravesen, Gregory, Larsen, Petersen & Sandberg), have been investigated in the atmosphere of Córdoba (Spain) during the period of April, 1983 to March, 1985 by means of the volumetric (...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：:Asthma morbidity and mortality has increased. One of the possible causes is the excessive use of beta agonists. The aim of this study is to compare the effects of six week treatment with beclomethasone alone (Ibec) or the combination of beclomethasone-salmeterol (Ibe + Isal) on serum potassium (K), CPK-MB and ECG in c...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0301-0546(01)79010-6
更新日期：2001-01-01 00:00:00
abstract：:The authors selected 28 severe asthmatic children in order to compare the effect of different prophylactic regimens. Patients experiencing at least one wheezing attack per week were included in the study. In a randomized manner, they were allocated Zaditen or Intal. After 8 weeks of active treatment and a 2 week wash-...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1983-01-01 00:00:00
abstract：:Sera from 19 patients with hypersensitivity pneumonitis induced by avian antigens were studied in order to determine the presence of circulating autoantibodies. IgM and IgG rheumatoid factors were positive in 68% and 100% of the cases respectively. IgM-rheumatoid factor was detected with at least two methods, showing ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Leguminous are a cheap source of protein that are cultivated practically throughout the world. They are the main source of food in developing countries. In the Mediterranean area and Middle East, the most commonly consumed legumes are lentils and chickpea. In the United States, United Kingdom and south-east Asia, the ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/s0301-0546(02)79152-0
更新日期：2002-11-01 00:00:00
abstract：:This work deals with a study of the changes observed throughout the four seasons of the year concerning the number of fungi which can be found in the atmosphere of Barcelona. The results obtained will bring us to the conclusion that during the autumn and winter months the number of conidia per m3 is greater than in sp...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1983-07-01 00:00:00
abstract：:The search for specific antibodies against the Human Immunodeficiency Virus type-1 (Ab anti HIV 1), using an immunoenzymatic test and a subsequent confirmation test (Western Blot-WB) in patients who were previously positive or borderline at the first test, singled out from about 12500 tested subjects, fifteen patients...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：BACKGROUND:Adherence to pharmacotherapy reduces symptoms of asthma and rhinitis, however, little is known of its impact on school performance. OBJECTIVE:To evaluate the impact of pharmacotherapy in absenteeism and school performance in a child population. METHODS:A cross-sectional study, carried out in eight schools....
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.12.005
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Few previous reports of carrot-induced asthma have been confirmed by objective tests. Hypersensitivity to carrot is frequently associated with allergy to Apiaceae spices and sensitization to birch and mugwort pollens. CLINICAL CASE:A 40-year-old cook woman was seen with sneezing, rhinorrhea, contact urticar...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13080934
更新日期：2005-09-01 00:00:00
abstract：:Immunotherapy delivered a new therapeutic option to the oncologist: Ipilimumab (anti-CTLA-4), Nivolumab and Pembrolizumab (anti-PD1), and Atezolizumab (anti-PD-L1) increase overall survival and show a better safety profile compared to chemotherapy in patients with metastatic melanoma, lung, renal cancer among others. ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2018.04.005
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare disease which can cause severe morbidity and mortality. The aim of this study is to evaluate the clinical manifestation and course of DRESS syndrome. METHODS:We conducted a retrospective analysis of prospectively collected data...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2013.08.003
更新日期：2015-01-01 00:00:00
abstract：:The study was performed on 22 patients with sensitivity to aspirin which manifested as urticaria and angioedema. Sensitivity to aspirin was established based on the anamnesis of urticaria and angioedema occurring after ingestion of aspirin and oral challenge tests with acetylsalicylic acid. At first, the threshold dos...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1988-09-01 00:00:00
abstract：:It has recently been published patients suffering from urticaria or anaphylaxia induced by nematodes usually parasitizing fishs or cephalopode, in whom, Anisakis simplex (AK) sensitization prevalence was detected up to 37%. We tried out a prospective study to evaluate the presence of AK specific-IgE in an asthmatic po...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:Human bocavirus (HBoV) was recently discovered and identified as an important cause of respiratory infection in young children. However, the relationship between HBoV-bronchiolitis and the development of recurrent wheezing has not yet been established. OBJECTIVE:We designed this study in order to describe t...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.07.004
更新日期：2016-09-01 00:00:00
abstract：:It is suggested that increased reactivity in asthma is not limited to the bronchi but also exists in the mediator releasing system. We have previously observed that the basophils of atopic asthmatics are degranulated by polymyxin B in vitro. The present study attempts to relate this basophil degranulation to atopy. Th...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-09-01 00:00:00
abstract：BACKGROUND:Due to the high prevalence of recurrent wheezing in the pediatric population, it is important to be able to identify environmental risk factors that may affect the etiology of asthma in several regions. OBJECTIVE:to identify possible risk factors associated with asthma in children (9-12 years old) in Passo ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2019.07.003
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Yellow dye tartrazine is a potential cause of exacerbations of asthma, allergic rhinitis and urticaria in atopic patients. The Brazilian Sanitary Surveillance Agency (ANVISA) published a consultation about the possibility of issuing a label warning addressing these potential effects of food and drugs contain...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2009.09.009
更新日期：2010-05-01 00:00:00
abstract：:Common variable immunodeficiency is a disorder characterised by hypogammaglobulinemia with B-lymphocytes in peripheral blood and repeated infections. We report a child with a diagnosis of diabetes mellitus and celiac disease during lactation, and in whom common variable immunodeficiency was diagnosed at the age of 5. ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
abstract：:For one year dust was sampled monthly from a single mattress. Until August mite counts were at background levels. In September and October there was a burst in the counts for the house-dust mite, Dermatophagoides farinae and for the house mite, Glycyphagus domesticus. Their occurrence might be interpreted as a respons...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1983-05-01 00:00:00
abstract：BACKGROUND:Diamine oxidase (DAO) is a polyamine-degrading enzyme also implicated in histamine metabolism. Chronic urticaria (CU) has a wide spectrum of clinical presentations and causes. Anisakis sensitisation associated chronic urticaria (CU+) has been characterised as a phenotype with different clinical and immunolog...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.01.009
更新日期：2015-11-01 00:00:00
abstract：:A prospective, multicenter pharmacovigilance study was carried out to evaluate the safety of a new 7-dose treatment schedule of subcutaneous immunotherapy as opposed to the conventional 13 doses normally recommended. The study was carried out in 14 centers and included 261 patients (children and adults) with respirato...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：10.1016/s0301-0546(04)79217-4
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:In this work we analyzed the allergological importance of Tyrophagus putrescentiae (Tp) in Huelva (SE Spain). We studied the level of exposition and the grade of sensitization to Tp in a group of patients sensitized to Dermatophagoides pteronyssinus (Dpt). The allergenic cross-reactivity between Dpt and Tp w...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13077746
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:Anaphylaxis is an acute multisystemic and potentially fatal reaction, resulting from the rapid release of inflammatory mediators. Its exact prevalence is unknown. In children, foods are the most significant triggers for IgE-mediated anaphylaxis. OBJECTIVES:To characterise the cases of anaphylaxis evaluated ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2010.12.012
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Autosomal dominant hyper-IgE syndrome (AD-HIES) is a primary immunodeficiency mainly caused by mutations in STAT3, a signalling molecule implicated in the development of appropriate immune responses. We aimed to characterise the innate immune response in AD-HIES. METHODS:The frequency of innate immune cells...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2014.11.002
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Macrolides are useful in a wide range of bacterial infections including upper and lower respiratory tract, skin, and sexually transmitted diseases and are used in Helicobacter pylori eradication regimen. Skin symptoms occurring during drug therapy are mostly attributed to the antibiotic, causing considerable...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2010.06.008
更新日期：2011-07-01 00:00:00
abstract：:Olea Europaea is the most important allergenic tree in Southern Italy and in the Naples area. Its pollination period lasts from the middle of April to the end of June. In our pollinosis patients we observed frequency of sensitization of 13.05% to Olea pollen. That means that this pollen follows Parietaria (47.80%) and...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-05-01 00:00:00
