Abstract:
BACKGROUND:It is considered that farm areas protect young patients from allergy and asthma due to high exposure to endotoxins. AIM:To compare CD4+/CD25+ T-regulatory cells and forkhead transcription factor Foxp3 expression in asthmatic children allergic to house dust mites (HDM) living in rural and farm areas. MATERIALS AND METHODS:This was a prospective analysis of 35 children living in farm areas (n=19) and rural areas (n=16), aged 8-16, with allergic rhinitis (allergic to dust mites) and newly diagnosed asthma. Surface molecule CD4+CD25+Foxp3+ expression on cultured PBMCs was estimated by flow cytometry using fluorophore-conjugated monoclonal antibodies in each patient. RESULTS:Thirty-five children were included into the analysis: 19 children living in farm areas and 16 in rural areas. Within and between-groups (farm area vs. rural area) differences in CD4+/CD25+ and CD4+/CD25+Foxp3+ cell expression did not reach the level of significance. CONCLUSION:The current analysis showed that CD4+/CD25+ and CD4+/CD25+Foxp3+ cell expression was not associated with place of living in asthmatic children sensitive to HDM.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Fuss P,Bal K,Jerzyńska J,Podlecka D,Stelmach W,Stelmach Idoi
10.1016/j.aller.2018.04.003subject
Has Abstractpub_date
2019-01-01 00:00:00pages
43-46issue
1eissn
0301-0546issn
1578-1267pii
S0301-0546(18)30073-9journal_volume
47pub_type
杂志文章abstract:INTRODUCTION AND OBJECTIVES:The reproducibility of the adverse reaction increases the suggestiveness of a history of food allergy. However, the positive predictive value (PPV) of multiple adverse reaction episodes for the diagnosis of IgE-mediated food allergy is not known. This evaluation was the objective of our stud...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2018.10.006
更新日期:2019-01-01 00:00:00
abstract::This study was motivated by the discrepancy in the results of published studies on the amount of histamine released following the intravascular administration of iodinated contrast media (ICM) in humans. From a group of patients due to undergo cardiac catheterization, we selected 45 subjects with no history of atopy. ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::The search for specific antibodies against the Human Immunodeficiency Virus type-1 (Ab anti HIV 1), using an immunoenzymatic test and a subsequent confirmation test (Western Blot-WB) in patients who were previously positive or borderline at the first test, singled out from about 12500 tested subjects, fifteen patients...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Few previous reports of carrot-induced asthma have been confirmed by objective tests. Hypersensitivity to carrot is frequently associated with allergy to Apiaceae spices and sensitization to birch and mugwort pollens. CLINICAL CASE:A 40-year-old cook woman was seen with sneezing, rhinorrhea, contact urticar...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1157/13080934
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Food allergy can have a major impact on quality of life of children and their parents. Questionnaires have been developed to measure the impact of this disorder. We aimed to validate the EuroPrevall questionnaire on Food Allergy-Quality of Life Questionnaire, Parent Form (FAQLQ-PF) and the Food Allergy Indep...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2017.06.004
更新日期:2018-01-01 00:00:00
abstract::Specific immunotherapy consists of the administration of allergen extracts to patients with allergic disease to achieve clinical tolerance to the causative allergens. Currently, it is the only etiologic treatment for respiratory allergy. A World Health Organization opinion paper published in 1997 defines immunotherapy...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/s0301-0546(04)79300-3
更新日期:2004-05-01 00:00:00
abstract::The increase in the consumption of tropical nuts in the Northern Hemisphere during the last years, has evolved in a simultaneous enhancement of allergic IgE mediated (Hypersensitivity type 1) reported cases produced by this kind of food. The Brazil nut is the seed of the Bertholletia excelsa tree (Family Lecythidaceae...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract::A lot of recent works point out the role of the eosinophil as one of the most harmful cells in asthma. Eosinophilic granules contain strongly basiec cytotoxic proteins. Some of these proteins were shown to damage airway epithelial cells and degranulate basophils and mast cells. The concentration of eosinophil-derived ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:Fish is a potent food allergen. The aim of this work is to demonstrate that dogfish, a small shark, has low allergenicity in both its clinical tolerance as well as its molecular structure. METHODS:We present a study of 34 paediatric patients with IgE-mediated immediate reactions after eating fish. The diagn...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2015.05.007
更新日期:2016-03-01 00:00:00
abstract::This study reports on the usefulness of skin mast cell quantification (mast cells(mm2) as a parameter for the diagnosis of atopic dermatitis (AD) and for determining the efficacy of the therapeutic measures employed. Fifteen children with AD of moderate to extreme severity, and which started within the first two years...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:Common variable immunodeficiency (CVID) is characterised by hypogammaglobulinaemia and a broad clinical spectrum, mainly showing recurrent bacterial infections accompanied sometimes by increased susceptibility to chronic lung disease, autoimmunity, and neoplastic diseases. OBJECTIVES:To evaluate the clinica...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2013.01.007
更新日期:2014-05-01 00:00:00
abstract::The reactivity of complement (C) with housedust allergen has been investigated in separate groups of sera from atopic patients with seasonal hay fever, bronchial asthma, atopic dermatitis, animal dander allergy or asthmatic bronchitis as compared to controls. Complement consumption was more pronounced on average in th...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::Thanks to its excellent safety profile, sublingual immunotherapy has served as a basis for launching two important lines of research in current allergology: sublingual immunotherapy with pharmaceutical registry (oral lyophilizates or tablets), and sublingual immunotherapy with food. At present, clinical trials are bei...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(08)75223-6
更新日期:2008-09-01 00:00:00
abstract::Toll-like receptors (TLRs) are a family of transmembrane receptors that have been preserved throughout evolution and which selectively recognize a broad spectrum of microbial components and endogenous molecules released by injured tissue. Identification of these ligands by TLRs triggers signalling pathways which lead ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/j.aller.2009.04.004
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:According to current knowledge, asthma is basically an inflammatory process. Its causes and physiopathological mechanisms are various. The final result is a recurrent obstructive bronchial process, with sibilants and/or dypnea, which causes an upset in functional respiratory tests, among which the maximum re...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(04)79240-x
更新日期:2004-07-01 00:00:00
abstract::The importance of insect dust as inhalant allergen (e.g. locust, cockroach, mite, butterfly, bee, fly, etc.) is frequently underestimated as a cause of allergic conjunctivitis, rhinitis and bronchial asthma. The high allergenic potency of insect dust is demonstrated in cases of occupational allergy against locust. Thi...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1979-05-01 00:00:00
abstract::A 34-year-old woman referred episodes of gastrointestinal disorders and sometimes angioedema of the lips which appeared within 2 hours from the ingestion of packed food like biscuits, cereals or fruit juice. A patch test with the standard European series and with food preservatives was positive for fragrances mix. The...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1157/13112995
更新日期:2007-11-01 00:00:00
abstract::For one year dust was sampled monthly from a single mattress. Until August mite counts were at background levels. In September and October there was a burst in the counts for the house-dust mite, Dermatophagoides farinae and for the house mite, Glycyphagus domesticus. Their occurrence might be interpreted as a respons...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1983-05-01 00:00:00
abstract:BACKGROUND:Anaphylaxis is a sudden, severe, and potentially life-threatening allergic reaction, affecting a portion of allergic patients. Adrenaline is the first-line medication for anaphylaxis and available in many parts of the world as adrenaline autoinjectors (AAIs). OBJECTIVE:Aim of this study was to determine att...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2019.07.009
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Despite growing evidence suggesting potential association between innate and adaptive immunity in viral-induced acute asthma, there is paucity of data in this area. OBJECTIVE:This study aimed to investigate the association of innate and adaptive immunity with acute asthma attacks by analysing the role of IF...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2016.07.003
更新日期:2017-01-01 00:00:00
abstract::Since half of the fetal transplantation antigens are paternal in origen, the conceptus could be considered as a particular allogeneic graft not rejected by the mother. The reason for this particular kind of tolerance remains mostly unknown, and an enormous amount of experimental work, clinical observations and hypothe...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract::The inflammation markers in asthma can help the prognosis, diagnosis and monitoring of the respiratory illness. The adhesion molecules (AM) are membrane glycoproteins that intervene in the contact between the two cells or between the cell and the extracellular matrix. Their aim is to maintain the contact between two c...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-05-01 00:00:00
abstract::Atopic dermatitis (AD) is a multifaceted disease that involves a complex interplay between the skin and the immune system. The course of the disease depends strongly on the genetic background of the patient and on yet poorly-defined environmental factors. Changes in lifestyle could be behind the dramatic rise in the p...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/j.aller.2017.07.002
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:High sensitive C-reactive protein (hs-CRP) has been shown to be associated with asthma in recent studies. However, the relationship between hs-CRP and the control of asthma has not been clearly identified yet. OBJECTIVE:To investigate the association of hs-CRP with asthma control test (ACT), which reveals t...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2011.10.002
更新日期:2012-11-01 00:00:00
abstract::Authors studied nasal hypersensitivity (NH) behaviour on 41 subjects suffering from recurrent adenoids disease during their paediatric age. All subjects underwent clinical history, ENT examination, skin-test, RAST and non-specific nasal provocation test with histamine and assessment of the amount of sneezes. The resul...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:Inhaled corticosteroids are used to treat infants with troublesome asthma-like symptoms but their effect on the lung function of these young patients is controversial. MATERIAL AND METHODS:Forty-four infants with recurrent wheezing (more than 3 episodes) and family history of asthma completed this randomise...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,随机对照试验
doi:10.1016/s0301-0546(09)71105-x
更新日期:2009-03-01 00:00:00
abstract::The aminoacid contents of native chestnut and its powdered form were studied. It was found that it has low cystine and methionine contents but if it is supplemented accordingly, the chestnut pulp can well be used for infant feeding. More than 50 infants were fed with chestnuts, and only in two cases was there intolera...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract:BACKGROUND:The clinical relevance of elevated basal serum tryptase (eBST ≥ 11.4 ng/ml) often remains unclear. METHODS:BST was assessed in 15,298 patients attending our outpatient clinic. Frequency and severity of anaphylaxis was compared in 900 patients with eBST and 900 patients with normal BST. The prevalence of eBS...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2014.05.002
更新日期:2014-11-01 00:00:00
abstract::Perioperative anaphylactic reactions are immediate, hypersensitive reactions that are potentially life-threatening resulting from a sudden release of mediators from mast cells and basophiles, due to either immune (IgE or non-IgE mediated) or non-immune mechanisms. The most frequent causing agents are neuromuscular blo...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/j.aller.2013.07.012
更新日期:2015-03-01 00:00:00
abstract::Rhinomanometry is a technique which studies the resistance of the nasal airways. It also permits us to measure their variations during NPT. This work has analysed the different methods of rhinomanometry (previously active, previously passive and late), commenting on its advantages and disadvantages. Bearing in mind th...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00