Abstract：
BACKGROUND:Several authors have reported an increase in leukotriene C4 in the premenstrual phase in women with severe premenstrual asthma, indicating that antileukotrienes could be used in treatment. OBJECTIVE:To analyse the role of leukotrienes in premenstrual asthma. METHODS:A questionnaire on respiratory symptoms and peak flow during one complete menstrual cycle was given to women of fertile age to define them as asthmatics who suffered from premenstrual asthma or not. Premenstrual asthma (PMA) was defined as a clinical or functional deterioration (≥20%) in the premenstrual phase compared with the preovulatory phase. Blood samples to measure leukotriene C4 were taken during the preovulatory and premenstrual phases. RESULTS:Blood samples were taken in 62 asthmatic women, 34 of whom (54.3%) presented PMA criteria, all with a premenstrual deterioration of between 20 and 40%. There was no difference in leukotriene C4 levels between the preovulatory and premenstrual phases in the women who suffered from PMA (1.50ng/mL vs. 1.31ng/mL; p=0.32) and those who did not (1.40ng/mL vs. 1.29ng/mL; p=0.62). Neither were there any differences in leukotriene levels between women with or without PMA. The results were similar for each category of asthma severity. CONCLUSIONS:Our data show that leukotriene C4 does not appear to be involved in the pathogenesis of premenstrual asthma, or support the use of anti-leukotrienes in the specific treatment of premenstrual asthma, at least in women with a moderate premenstrual deterioration. No differences appeared in any of the categories of asthma severity.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Pereira-Vega A,Sánchez Ramos JL,Maldonado Pérez JA,Vázquez Oliva R,Bravo Nieto JM,Vázquez Rico I,Ignacio García JM,Romero Palacios P,Alwakil Olbah M,Medina Gallardo JFdoi
10.1016/j.aller.2011.09.007subject
Has Abstractpub_date
2012-11-01 00:00:00pages
368-73issue
6eissn
0301-0546issn
1578-1267pii
S0301-0546(11)00328-4journal_volume
40pub_type
杂志文章abstract：BACKGROUND:Food allergy can have a major impact on quality of life of children and their parents. Questionnaires have been developed to measure the impact of this disorder. We aimed to validate the EuroPrevall questionnaire on Food Allergy-Quality of Life Questionnaire, Parent Form (FAQLQ-PF) and the Food Allergy Indep...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.06.004
更新日期：2018-01-01 00:00:00
abstract：:We present the clinical case of a 8-years-old boy suffering a fixed drug reaction attributed to the oral intake of loratadine. He is an atopic child with perennial rhinitis and asthma and marked hypersensitivity to the house-dust mite Dermatophagoides pteronyssinus who is receiving inhaled corticosteroids and b2-agoni...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(03)79199-x
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:Assessment of asthma with a control test has been suggested as a relevant approach in recent years. However, no biomarker of systemic inflammation has been included in the assessment of asthma control. OBJECTIVE:To evaluate plasma paraoxonase (PON1), total oxidant status (TOS), and total antioxidant status ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2014.05.009
更新日期：2015-07-01 00:00:00
abstract：:We report immunological studies performed in 19 sera from 4 children with idiopathic pulmonary hemosiderosis (IPH). Circulating C1q binding immune complexes (IC) were found in 3/4 of the patients during the acute phase. One child showed IC in 4 consecutive crises but they disappeared very rapidly (within 36 hours). On...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The effect of alcohol ingestion on the prognosis of chronic liver diseases was studied'n. Among 880 patients with chronic liver diseases the percentage of alcoholics was high, 33%, compared to 3.2% in the control group. The period of survival time is decreased by one half in patients with regular alcohol ingestion. Ac...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1981-09-01 00:00:00
abstract：:Some authors succeded in binding the bradykinin in form of a haptene by an azo-bridge to the human gammaglobulin as a vehicle. In this way, the bradykinin has been supplemented to a complete antigen. The bradykinin as a strongly vasoactive substance causes--after a local intradermal injection--an intensive circumscrib...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1977-03-01 00:00:00
abstract：:It is suggested that increased reactivity in asthma is not limited to the bronchi but also exists in the mediator releasing system. We have previously observed that the basophils of atopic asthmatics are degranulated by polymyxin B in vitro. The present study attempts to relate this basophil degranulation to atopy. Th...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-09-01 00:00:00
abstract：:The aims of this report are: to investigate the kinetics of the E. coli lipopolysaccharide polyclonal response as a function of the background response, to test the capacity of lipopolysaccharide to activate presumably resting memory cells for IgM. Because mice do not produce a plaque-forming cell background against r...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:Neutrophil-lymphocyte ratio (NLR) is a test used to evaluate the systemic inflammation. There is little knowledge about the neutrophil-lymphocyte ratio in asthmatics. In our study, we aimed to evaluate NLR and to assess its relationship with clinical parameters in children with asthma. METHODS:Four hundred ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.09.005
更新日期：2016-07-01 00:00:00
abstract：:Five patients with atopic dermatitis, three males and two females, aged 2 to 17 years, had positive reactions to air allergens (Dermatophagoides pteronyssinus and/or farinae). All the patients suffered from severe recurrent dermatophytosis that responded poorly to antifungal treatment. The results of immunologic evalu...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(02)79135-0
更新日期：2002-09-01 00:00:00
abstract：BACKGROUND:The incidence of asthma is high, especially in young people, a population group that includes women of reproductive age. We reviewed recent publications on asthma control during pregnancy to avoid undesired effects on both the mother and fetus. The prevalence of rhinoconjunctivitis is also high, although thi...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1157/13075700
更新日期：2005-05-01 00:00:00
abstract：:The present prospective, open, observational study assessed the effect of the use of standard environmental control measures together with the application of an acaricide-containing aerosol of esbiol/benzyl benzoate/piperonyl butoxide/2-phenylphenol (Frontac) on several clinical and environmental parameters in patient...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：10.1016/s0301-0546(02)79096-4
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND:The clinical relevance of elevated basal serum tryptase (eBST ≥ 11.4 ng/ml) often remains unclear. METHODS:BST was assessed in 15,298 patients attending our outpatient clinic. Frequency and severity of anaphylaxis was compared in 900 patients with eBST and 900 patients with normal BST. The prevalence of eBS...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2014.05.002
更新日期：2014-11-01 00:00:00
abstract：:Clinical experience suggests that allergic signs and symptoms are more frequently observed in patients with systemic lupus erythematosus than in the general population. The aim of this paper was to evaluate the frequency of allergic clinical manifestations in systemic lupus erythematosus (SLE) by anamnesis. Sixty thre...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-07-01 00:00:00
abstract：:In a 19 year old patient suffering from CMC since the first months of life, clinical improvement accompanied by correction of the immunologic defect was achieved by Transfer Factor therapy. After 12 months from the last administration of Transfer Factor the improvement persisted. The positive outcome of the treatment ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:In medical literature, there are many cases reported of anaphylaxis due to fruits, before or after allergic reactions to latex. We present two atopic patients, with allergy to latex (by clinical history, positive skin test and RAST). Both patients showed a positive skin test and RAST to fruits (banana, kiwi, avocado a...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:Inhaled corticosteroids are used to treat infants with troublesome asthma-like symptoms but their effect on the lung function of these young patients is controversial. MATERIAL AND METHODS:Forty-four infants with recurrent wheezing (more than 3 episodes) and family history of asthma completed this randomise...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,随机对照试验
doi：10.1016/s0301-0546(09)71105-x
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:Epidemiological evidence suggests the existence of a direct link between allergic rhinitis (AR) and asthma. Several studies also support the presence of small-airway dysfunction (SAD) in non-asthmatic children with AR. However, it remains unknown whether SAD can predict the progression of AR to asthma. Our o...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.09.025
更新日期：2018-01-01 00:00:00
abstract：:The protease-antiprotease balance and concentration of immunoglobulin was evaluated in some respiratory tract diseases. Analysis was carried out on 24 patients with atopic bronchial asthma, 21 with chronic bronchitis, 27 with bronchiectasis and 18 healthy smokers volunteers. In examination of BAL fluid some selective ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1987-07-01 00:00:00
abstract：:Sera from 19 patients with hypersensitivity pneumonitis induced by avian antigens were studied in order to determine the presence of circulating autoantibodies. IgM and IgG rheumatoid factors were positive in 68% and 100% of the cases respectively. IgM-rheumatoid factor was detected with at least two methods, showing ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Autosomal dominant hyper-IgE syndrome (AD-HIES) is a primary immunodeficiency mainly caused by mutations in STAT3, a signalling molecule implicated in the development of appropriate immune responses. We aimed to characterise the innate immune response in AD-HIES. METHODS:The frequency of innate immune cells...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2014.11.002
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Few data are available concerning the time trends and risk factors associated with allergic rhinitis (AR) in schoolchildren in Hungary. METHODS:At an interval of six years, parents of 6-12-year-old children completed identical ISAAC-based and additional questionnaires related to possible risk factors. RESU...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.02.010
更新日期：2017-01-01 00:00:00
abstract：:Anaphylaxis is a systemic reaction which can be very dangerous in many patients. In addition to the most common antigens (drugs, venoms, foods), physical exercise can provoke anaphylaxis in the sensitized patients. The mechanism of this reaction is still unknown. In this report, we describe a case of exercise-induced ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
abstract：:A study on the presence of specific precipitins against tobacco antigens was done in a population of 361 healthy cigrette smokers and in a group of 60 healthy non-smokers. The tests were made by the gel diffusion technique of Ouchterlony using tobacco extract prepared by the Coca method. A positive precipitation react...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1977-11-01 00:00:00
abstract：BACKGROUND:Children with IgE-mediated cow's milk allergy (IgE-CMA) often tolerate baked milk within a wheat matrix. In our study we evaluated the impact of wheat matrix and of little standardised cooking procedures on tolerance of baked milk. We also tested tolerance versus parmigiano reggiano (PR) and whey-based parti...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2016.03.005
更新日期：2016-01-01 00:00:00
abstract：:A total of 181 allergic patients were studied and classified according to the causal antigen, 92 patients were sensitized to the mixed grass pollen, 55 to house dust, 28 to Candida albicans, 31 patients with egg allergy and 25 with milk allergy. All of them presented strong positivity to anamnesis, intracutaneous test...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Although not yet clear, the etiology of sarcoidosis may be linked to seasonal, environmental and genetic factors; mycobacterial or other infections. To the best of our knowledge there is no data suggesting any connection between the onset of sarcoidosis and specific allergen immunotherapy in the medical literature. Du...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13099093
更新日期：2007-01-01 00:00:00
abstract：:Over the past three decades, the number of obese people has risen steadily. The chronic low-grade inflammatory state and the non-specific activation of the immune system have contributed greatly to the development of obesity-related immunology. Food allergy as a kind of inflammatory disease with abnormal immune respon...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2019.06.004
更新日期：2020-01-01 00:00:00
abstract：:Twenty-eight patients with a confirmed histological diagnosis of adenocarcinoma of the prostate received BCG immunotherapy in addition to conventional therapy. Patients receiving BCG exhibited significant changes in IgA, IgM, WBC's, acid phosphatase and in cutaneous hypersensitivity when compared to an age-related con...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1978-07-01 00:00:00
abstract：:The authors selected 28 severe asthmatic children in order to compare the effect of different prophylactic regimens. Patients experiencing at least one wheezing attack per week were included in the study. In a randomized manner, they were allocated Zaditen or Intal. After 8 weeks of active treatment and a 2 week wash-...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1983-01-01 00:00:00
