Abstract:
:Twenty-eight patients with a confirmed histological diagnosis of adenocarcinoma of the prostate received BCG immunotherapy in addition to conventional therapy. Patients receiving BCG exhibited significant changes in IgA, IgM, WBC's, acid phosphatase and in cutaneous hypersensitivity when compared to an age-related control group of prostatic cancer patients receiving only conventional therapy. Survival from the time of diagnosis was 8 months longer in patients receiving BCG. Side effects of BCG vaccination were minimal consisting of local inflammation and pruritus at the site of inoculation. There were no deaths of systemic reactions.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Guinan PD,John T,Nagale V,Ablin RJsubject
Has Abstractpub_date
1978-07-01 00:00:00pages
293-6issue
4eissn
0301-0546issn
1578-1267journal_volume
6pub_type
杂志文章abstract:BACKGROUND:The pathogenesis of atopic dermatitis (AD) is still not completely understood. AD is characterized by the presence of clinical symptoms of both IgE antibody-mediated immediate hypersensitivity and specific T lymphocyte-mediated delayed hypersensitivity. OBJECTIVE:To evaluate the immunological mechanisms inv...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(04)79251-4
更新日期:2004-09-01 00:00:00
abstract::Toll-like receptors (TLRs) are a family of transmembrane receptors that have been preserved throughout evolution and which selectively recognize a broad spectrum of microbial components and endogenous molecules released by injured tissue. Identification of these ligands by TLRs triggers signalling pathways which lead ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/j.aller.2009.04.004
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:The incidence of asthma is high, especially in young people, a population group that includes women of reproductive age. We reviewed recent publications on asthma control during pregnancy to avoid undesired effects on both the mother and fetus. The prevalence of rhinoconjunctivitis is also high, although thi...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1157/13075700
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Anaphylaxis is an acute multisystemic and potentially fatal reaction, resulting from the rapid release of inflammatory mediators. Its exact prevalence is unknown. In children, foods are the most significant triggers for IgE-mediated anaphylaxis. OBJECTIVES:To characterise the cases of anaphylaxis evaluated ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2010.12.012
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Vitamin D plays a role in the immune system, however studies regarding this are scarce. This study aimed to evaluate the nutritional status of vitamin D in patients with Common Variable Immunodeficiency (CVID) or Ataxia-Telangiectasia (A-T) and to relate it to body composition, inflammatory ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2019.03.004
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Clinical research has shown that sublingual immunotherapy (SLIT) is effective and safe in moderate-severe allergic rhinitis (AR) induced by house dust mite (HDM). However, the sample size in many studies is small. Meanwhile, the controversy on the efficacy and safety in the very young children younger than f...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2016.10.016
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Assessment of asthma with a control test has been suggested as a relevant approach in recent years. However, no biomarker of systemic inflammation has been included in the assessment of asthma control. OBJECTIVE:To evaluate plasma paraoxonase (PON1), total oxidant status (TOS), and total antioxidant status ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2014.05.009
更新日期:2015-07-01 00:00:00
abstract::Some authors succeded in binding the bradykinin in form of a haptene by an azo-bridge to the human gammaglobulin as a vehicle. In this way, the bradykinin has been supplemented to a complete antigen. The bradykinin as a strongly vasoactive substance causes--after a local intradermal injection--an intensive circumscrib...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1977-03-01 00:00:00
abstract:UNLABELLED:Asthma is one of the most frequent chronic illnesses in paediatric age children. In the last reviews carried out by the group of experts (EPR II) in 1997, a chapter was included on education for the groups who are involved with looking after patients with asthma, and proposes the inclusion of questions focus...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,多中心研究
doi:
更新日期:2000-05-01 00:00:00
abstract::It is suggested that increased reactivity in asthma is not limited to the bronchi but also exists in the mediator releasing system. We have previously observed that the basophils of atopic asthmatics are degranulated by polymyxin B in vitro. The present study attempts to relate this basophil degranulation to atopy. Th...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1985-09-01 00:00:00
abstract:BACKGROUND:Asthma morbidity and mortality have been increasing. Data of asthma and respiratory mortality rates in Brazil are scarse. METHODS:We studied asthma and respiratory disease mortality rates in the state of So Paulo (capital and country side) from 1970 to 1996, as its relation with sales of drugs usually used ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(02)79084-8
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Food allergy can have a major impact on quality of life of children and their parents. Questionnaires have been developed to measure the impact of this disorder. We aimed to validate the EuroPrevall questionnaire on Food Allergy-Quality of Life Questionnaire, Parent Form (FAQLQ-PF) and the Food Allergy Indep...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2017.06.004
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:In recent years, traditional diets enriched with fresh plant-based foods have been gradually abandoned, increasing the consumption of animal foods and highly processed food. The aim of this study was to assess the effects of a nutritional intervention with a Traditional Mediterranean Diet in patients with ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2016.08.006
更新日期:2017-01-01 00:00:00
abstract::After isolating the soluble factors and observing their biological activity of "in vitro" IgE synthesis, we decided to study the changes these molecules exercise on the expression of lymphocytes of IgE (FcR epsilon). We saw that the fractions from healthy subjects inhibited the expression of receptors quantified by im...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Carboplatin (CP) hypersensitivity reactions have been reported in nearly 12 % of patients treated with this drug. The pathophysiologic mechanisms of these reactions have not been entirely elucidated. Various hypotheses are under discussion. CP hypersensitivity reactions could be IgE-mediated, caused by low-molecular p...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(03)79209-x
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Some studies indicate some causal relationship between obesity and asthma, while others show inconsistent results. Our objective was to evaluate the prevalence of asthma according to obesity in children. METHODS:A cross-sectional study, following the ISAAC study methodology, was conducted on two randomly se...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.aller.2012.05.011
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To report the results of treatment with infliximab in patients with refractory juvenile idiopathic arthritis (JIA). PATIENTS AND METHODS:A prospective study of four children with refractory JIA was carried out. Infliximab (100 mg) was administered in weeks 0, 2 and 6. Subsequently, the drug was administered ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1157/13101338
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Diamine oxidase (DAO) is a polyamine-degrading enzyme also implicated in histamine metabolism. Chronic urticaria (CU) has a wide spectrum of clinical presentations and causes. Anisakis sensitisation associated chronic urticaria (CU+) has been characterised as a phenotype with different clinical and immunolog...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2015.01.009
更新日期:2015-11-01 00:00:00
abstract::This work deals with a study of the changes observed throughout the four seasons of the year concerning the number of fungi which can be found in the atmosphere of Barcelona. The results obtained will bring us to the conclusion that during the autumn and winter months the number of conidia per m3 is greater than in sp...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1983-07-01 00:00:00
abstract:BACKGROUND:Atopy results from the interaction between genetic and environmental factors. The aim of our study was to clarify the association between the FcRIint2 polymorphic variant, the Glu237Gly mutation in exon 7 of FcepsilonRIbeta and (-590 C/T) Il-4 gene promoter polymorphism with atopy in a randomized Polish samp...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/s0301-0546(04)79227-7
更新日期:2004-03-01 00:00:00
abstract::This study reports on the usefulness of skin mast cell quantification (mast cells(mm2) as a parameter for the diagnosis of atopic dermatitis (AD) and for determining the efficacy of the therapeutic measures employed. Fifteen children with AD of moderate to extreme severity, and which started within the first two years...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract::An epidemiological study was performed in the students of Hacettepe University from various parts of Turkey to find the prevalence of asthma and allergic diseases and search for geographical differences in Turkey. A questionnaire related with symptoms of asthma and allergic diseases was distributed to 4600 students an...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract::From October 1982 to July 1983, 133 consecutive patients complaining of allergic symptoms were prick-tested with three storage mites (Acarus siro, Lepidoglyphus destructor, Tyrophagus putrescentiae) and two housedust mites (Dermatophagoides pteronyssinus and Dermatophagoides farinae). A total of 60 patients (45%) had ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::Authors studied nasal hypersensitivity (NH) behaviour on 41 subjects suffering from recurrent adenoids disease during their paediatric age. All subjects underwent clinical history, ENT examination, skin-test, RAST and non-specific nasal provocation test with histamine and assessment of the amount of sneezes. The resul...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:Macrolides are useful in a wide range of bacterial infections including upper and lower respiratory tract, skin, and sexually transmitted diseases and are used in Helicobacter pylori eradication regimen. Skin symptoms occurring during drug therapy are mostly attributed to the antibiotic, causing considerable...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2010.06.008
更新日期:2011-07-01 00:00:00
abstract::Proteolytic activity is fundamental to survival, so it is not surprising that all living organisms have proteases, especially seine protease. This enzyme in its numerous isoforms and homologues, constitutes the quintessential offence and defence factors, in the form of surface proteins, secreted molecules, gut digesti...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,评审
doi:10.1016/j.aller.2016.10.011
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Although it has been hypothesized that infections may play a preventive role in allergic diseases, the role of Helicobacter pylori (H. pylori) is not clear. In this study we aimed to determine the association between H. pylori infection and allergic inflammation. METHODS:H. pylori infection was assessed in ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1157/13120393
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Previous studies have shown that serum interleukin 33 serving as an "alarmin" is increased in children with asthma. The objective of this study was to assess the validity of serum IL33 test for early diagnosis of childhood asthma. METHODS:A literature search was performed in June 2016 using PubMed, Embase, ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.aller.2016.12.007
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The International Study of Asthma and Allergies in Childhood (ISAAC) identified trends in the prevalence of symptoms of asthma, rhinoconjunctivitis and eczema over a seven-year period. We hypothesised that environmental influences on the three diseases are different and therefore investigated the correlation...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章,多中心研究
doi:10.1016/j.aller.2011.11.004
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Several authors have reported an increase in leukotriene C4 in the premenstrual phase in women with severe premenstrual asthma, indicating that antileukotrienes could be used in treatment. OBJECTIVE:To analyse the role of leukotrienes in premenstrual asthma. METHODS:A questionnaire on respiratory symptoms ...
journal_title:Allergologia et immunopathologia
pub_type: 杂志文章
doi:10.1016/j.aller.2011.09.007
更新日期:2012-11-01 00:00:00