Abstract：
:The present prospective, open, observational study assessed the effect of the use of standard environmental control measures together with the application of an acaricide-containing aerosol of esbiol/benzyl benzoate/piperonyl butoxide/2-phenylphenol (Frontac) on several clinical and environmental parameters in patients suffering from perennial allergic rhinoconjunctivitis related to house dust mites (HDM). Fifty-five patients were enrolled and studied for one year. Both symptoms and the patients' quality of life (evaluated by the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ)) were assessed at several clinic visits. The amount of HDM antigen was semi-quantitatively estimated using the guanine test. We found a significant decrease (p < 0.001) in most nasal symptoms scores: sneezing, runny nose, stuffy nose and itching. The overall quality of life (QoL) score also showed a significant improvement during the study period; the mean score decrease found was 0.86 (CI 95 %, 0.54-1.17) (p < 0.001). Five of the seven domains included in the questionnaire decreased significantly: non-hayfever symptoms; practical problems; nasal symptoms; eye symptoms, and emotions. These QoL score decreases were found during the first 3 months and later remained stable at lower levels than at baseline. The content of guanine in dust samples decreased significantly from 2.17 0.75 to 1.43 0.68 (p < 0.001). No toxic adverse events were recorded. In conclusion, these results show an improvement in the quality of life and a clinical benefit of the long-term use of the new chemical acaricide tested, together with environmental measures, in the home of patients suffering from allergic respiratory pathology.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Malet A,Cisteró-Bahima A,Amat P,Lluch-Pérez M,Enrique-Miranda E,Alonso R,San Miguel M,Pueyo Mf MGdoi
10.1016/s0301-0546(02)79096-4keywords:
subject
Has Abstractpub_date
2002-03-01 00:00:00pages
85-93issue
2eissn
0301-0546issn
1578-1267pii
13029070journal_volume
30pub_type
杂志文章,多中心研究abstract：:Rhinomanometry is a technique which studies the resistance of the nasal airways. It also permits us to measure their variations during NPT. This work has analysed the different methods of rhinomanometry (previously active, previously passive and late), commenting on its advantages and disadvantages. Bearing in mind th...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：INTRODUCTION:Omalizumab has been demonstrated to be a successful therapy in the management of asthma through reduction of patient's symptoms and use of inhaled corticosteroids. The effect of omalizumab is achieved by immunoglobulin E (IgE) blockage and other secondary mechanisms resulting from this blockage. Because ot...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2011.09.011
更新日期：2012-09-01 00:00:00
abstract：:Asthma is a complex disease determined by the interaction of different genes and environmental factors. The first genetic investigations in asthma were candidate gene association studies and linkage studies. In recent years research has focused on association studies that scan the entire genome without any prior condi...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2014.07.004
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Allergy to cow's milk proteins has often been associated with dysfunction of the intestinal mucosa caused by chronic inflammation in infants. This study evaluated the protective effect of taurine on intestinal damage induced by beta-lactoglobulin (β-Lg) in Balb/c mice used as an animal model of allergy to co...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2018.07.010
更新日期：2019-01-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:Vitamin D plays a role in the immune system, however studies regarding this are scarce. This study aimed to evaluate the nutritional status of vitamin D in patients with Common Variable Immunodeficiency (CVID) or Ataxia-Telangiectasia (A-T) and to relate it to body composition, inflammatory ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2019.03.004
更新日期：2019-01-01 00:00:00
abstract：:Numerous reports had been published implicating IPPD and other amine-type antioxidants as the causative agents in patients with allergic sensitization following the use of industrial and household products that have black rubber in their composition. The amine-type antioxidants, used to stabilize the polymer chains an...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:Hypersensitivity reactions to aspirin and other NSAIDs occur in individuals genetically predisposed and exhibit different clinical manifestations, especially respiratory, cutaneous, and generalised. Five different phenotypes define distinct clinical pictures: aspirin-exacerbated respiratory disease, aspirin/NSAID cuta...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2016.08.010
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:One of the factors affecting compliance is the pharmaceutical formulation used. Many patients find it difficult to swallow tablets or capsules. The fast dissolving tablet (FDT) formulation could help to enhance patient compliance, because of its ease of administration and because no liquid is required to hel...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：10.1157/13088176
更新日期：2006-05-01 00:00:00
abstract：BACKGROUND:Several authors have reported an increase in leukotriene C4 in the premenstrual phase in women with severe premenstrual asthma, indicating that antileukotrienes could be used in treatment. OBJECTIVE:To analyse the role of leukotrienes in premenstrual asthma. METHODS:A questionnaire on respiratory symptoms ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2011.09.007
更新日期：2012-11-01 00:00:00
abstract：:Thanks to its excellent safety profile, sublingual immunotherapy has served as a basis for launching two important lines of research in current allergology: sublingual immunotherapy with pharmaceutical registry (oral lyophilizates or tablets), and sublingual immunotherapy with food. At present, clinical trials are bei...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(08)75223-6
更新日期：2008-09-01 00:00:00
abstract：:The relationship between ingestion of cow's milk and lymphocyte transformation in cow's milk allergic children was studied. Fifty-six children were selected. Nineteen of them suffered from cow's milk hypersensitivity (HCM); 22 were allergic to several agents except to cow's milk (HOE) and 15 normal and healthy childre...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Pseudo-allergic reactions against aspirin (ASA) and non-steroidal anti-inflammatory drugs (NSAIDs) are quite frequent. OBJECTIVE:Our aim was to determine tolerance of Celecoxib, a selective inhibitor of cyclooxygenase-2 (Cox-2), by oral challenge test in patients who showed skin reactions (diffuse erythema ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13108222
更新日期：2007-07-01 00:00:00
abstract：:Twenty-eight patients with a confirmed histological diagnosis of adenocarcinoma of the prostate received BCG immunotherapy in addition to conventional therapy. Patients receiving BCG exhibited significant changes in IgA, IgM, WBC's, acid phosphatase and in cutaneous hypersensitivity when compared to an age-related con...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1978-07-01 00:00:00
abstract：:In clinical allergology and particularly during childhood, we quite frequently encounter patients who are allergic to milk. This has usually been confirmed by the clinical history and by skin testing. Statistics show a sensitization to cows' milk of between 0.3 and 7% of the world's population. In view of the diversit...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1978-05-01 00:00:00
abstract：:Platelet-activating factor (PAF), identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine, exhibits potent proinflammatory properties. PAF is produced by numerous cell types, including endothelial cells, neutrophils, monocytes, macrophages, basophils, eosinophils and mastocytes. Since the discovery and identi...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：
更新日期：1997-09-01 00:00:00
abstract：:Some authors succeded in binding the bradykinin in form of a haptene by an azo-bridge to the human gammaglobulin as a vehicle. In this way, the bradykinin has been supplemented to a complete antigen. The bradykinin as a strongly vasoactive substance causes--after a local intradermal injection--an intensive circumscrib...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1977-03-01 00:00:00
abstract：:The system that protects body from infectious agents is immune system. On occasions, the system seldom reacts with some foreign particles and causes allergy. Allergies of the ear, nose and throat (ENT) often have serious consequences, including impairment and emotional strain that lowers the quality of life of patient...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2016.10.010
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Cytokines, including interleukin-2 (IL-2) and interferon-gamma (IFN-γ), seem to play a role in the pathogenesis of juvenile idiopathic arthritis (JIA). The aim of this study was to investigate the associations of IL-2 and IFN-γ single nucleotide polymorphisms (SNPs) with susceptibility to JIA in an Iranian p...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.10.005
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Asthma hospitalization rates in Chilean children have increased in the last 14 years, but little is known about the factors associated with this. OBJECTIVE:Describe clinical characteristics of children hospitalized for asthma exacerbation. METHODS:Observational prospective cohort study in 14 hospitals. Ove...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.aller.2018.02.006
更新日期：2018-01-01 00:00:00
abstract：:The studies for determining the effects of dialyzable leukocyte extracts (transfer factor) as reflected in recovery of E-rosetting capacity in trypsinised lymphocytes (recovery-assay) suggested the following: 1. Dialyzable leukocyte extracts contain an inhibitor with a molecular weight of about 5000 (fraction I). 2. T...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1982-05-01 00:00:00
abstract：BACKGROUND:Due to the high prevalence of recurrent wheezing in the pediatric population, it is important to be able to identify environmental risk factors that may affect the etiology of asthma in several regions. OBJECTIVE:to identify possible risk factors associated with asthma in children (9-12 years old) in Passo ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2019.07.003
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Food allergy can have a major impact on quality of life of children and their parents. Questionnaires have been developed to measure the impact of this disorder. We aimed to validate the EuroPrevall questionnaire on Food Allergy-Quality of Life Questionnaire, Parent Form (FAQLQ-PF) and the Food Allergy Indep...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.06.004
更新日期：2018-01-01 00:00:00
abstract：:The search for specific antibodies against the Human Immunodeficiency Virus type-1 (Ab anti HIV 1), using an immunoenzymatic test and a subsequent confirmation test (Western Blot-WB) in patients who were previously positive or borderline at the first test, singled out from about 12500 tested subjects, fifteen patients...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：:An epidemiological study was performed in the students of Hacettepe University from various parts of Turkey to find the prevalence of asthma and allergic diseases and search for geographical differences in Turkey. A questionnaire related with symptoms of asthma and allergic diseases was distributed to 4600 students an...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：BACKGROUND:Since gamma interferon release assays (IGRAs) cannot differentiate between active tuberculosis and latent tuberculosis infection (LTBI), development of rapid and specific diagnosis tools are essential for discriminating between active tuberculosis (TB) from LTBI. Both IGRAs are based on Mycobacterium tubercu...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.09.004
更新日期：2016-07-01 00:00:00
abstract：:Toll-like receptors (TLRs) are a family of transmembrane receptors that have been preserved throughout evolution and which selectively recognize a broad spectrum of microbial components and endogenous molecules released by injured tissue. Identification of these ligands by TLRs triggers signalling pathways which lead ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2009.04.004
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare disease which can cause severe morbidity and mortality. The aim of this study is to evaluate the clinical manifestation and course of DRESS syndrome. METHODS:We conducted a retrospective analysis of prospectively collected data...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2013.08.003
更新日期：2015-01-01 00:00:00
abstract：:This paper aims to establish the diagnostic reliability of the Prick test and its correlation to other techniques used in allergologic diagnosis: intracutaneous testing, RAST, hemagglutination, histamine liberation test. All of these tests were realized in 55 patients with bronchial asthma and with marked sensitizatio...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND:Pollens represent a rich source of proteins that are also potential elicitors of IgE-mediated pollen allergy. Sensitisation to panallergens could play an important role in diagnosis and specific immunotherapy, because these molecules are present in different plant pollens and plant foods and have marked stru...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.05.002
更新日期：2016-03-01 00:00:00
abstract：:We report the case of a 42-year-old non-smoking man, who had worked as a carpenter for 6 years and who reported a history of rhinorrhea, paroxysmal sneezing, nasocular pruritus, lacrimation, wheezing and dyspnea attacks while preparing a mixture to seal the junctures between wooden panels. Allergy study consisted of s...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(05)73251-1
更新日期：2005-11-01 00:00:00
