Abstract：
INTRODUCTION AND OBJECTIVES:Vitamin D plays a role in the immune system, however studies regarding this are scarce. This study aimed to evaluate the nutritional status of vitamin D in patients with Common Variable Immunodeficiency (CVID) or Ataxia-Telangiectasia (A-T) and to relate it to body composition, inflammatory and bone metabolism markers. PATIENTS AND METHODS:This is a cross-sectional and controlled study involving 24 patients of both sexes (59.3% male), aged 8-56 years, with CVID (n=15) or A-T (n=9). The following variables were evaluated: body mass index (BMI), 25-hydroxyvitamin D (25 (OH) D), hepatic profile, parathormone, calcium, phosphorus, alkaline phosphatase, interleukin 6 and high-sensitivity C-reactive protein. RESULTS:The median age was 26.0 years. A deficiency of 25 (OH) D was found in four A-T patients (44%) and two CVID patients (13%). Nine patients with CVI (60%) and six with A-T (66.7%) were overweight and underweight, respectively. There was a negative correlation between vitamin D and fat mass in the CVID group, and vitamin D and BMI in the A-T group. Vitamin D was negatively associated with the percentage of total fat among the patients (β - 0.842, 95% CI: -1.5-0.17, p=0.015), R2=0.21, after adjusting for sex and age. CONCLUSION:Vitamin D deficiency occurred in a quarter of the patients although there was no difference between the patient and the control group; without association with bone and inflammation biomarkers. The percentage of fat and BMI were negatively associated with the concentrations of 25 (OH) D.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Cruz JRS,Silva R,Andrade IGA,Fonseca FLA,Costa-Carvalho BT,Sarni ROSdoi
10.1016/j.aller.2019.03.004subject
Has Abstractpub_date
2019-01-01 00:00:00pages
499-505issue
5eissn
0301-0546issn
1578-1267pii
S0301-0546(19)30049-7journal_volume
47pub_type
杂志文章abstract：:In normal individuals the 5/9 monoclonal antibody (5/9 MAb) recognizes a T-cell fraction that includes all T lymphocytes with inducer activities. Here, circulating 5/9+ and 5/9- T lymphocytes were isolated from tuberculim skin-positive subjects and the proliferative response induced by PPD was investigated. The result...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1987-03-01 00:00:00
abstract：:The etiological importance of the dietary factor as related to infantile bronchial asthma is not, at times, sufficiently taken into consideration. Nevertheless, many times foods or their components are capable of provoking asthmatic symptoms. A group of asthmatic children was studied with the goal of more throughly co...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：BACKGROUND:The International Study of Asthma and Allergies in Childhood (ISAAC) identified trends in the prevalence of symptoms of asthma, rhinoconjunctivitis and eczema over a seven-year period. We hypothesised that environmental influences on the three diseases are different and therefore investigated the correlation...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.aller.2011.11.004
更新日期：2012-09-01 00:00:00
abstract：:The percentages and absolute numbers of T, B and "null" cells were studied in 100 allergic patients and compared with values observed in 35 healthy age matched control subjects. T cells were identified by their ability to form spontaneous rosettes with SRBC (E-RFC) and B cells by their complement receptor that allows ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:The results of the cutaneous tests with fungus, and the repercussion of the fungal allergens in asthma via inhalatory route has been a controversial subject for many years. The lack of characterization, purification and standardization of the allergens make the results of the cutaneous tests highly variable. The diagn...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1986-07-01 00:00:00
abstract：:In a previous study we had found a high correlation between the positive reaction to standard house dust and to a mites pool extract of 0.86. The study had indicated that the dominant mite found in standard house dust in Barcelona seemed to be D. pteronyssinus. We wished to further confirm this finding by comparing sk...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：BACKGROUND:Clinical research has shown that sublingual immunotherapy (SLIT) is effective and safe in moderate-severe allergic rhinitis (AR) induced by house dust mite (HDM). However, the sample size in many studies is small. Meanwhile, the controversy on the efficacy and safety in the very young children younger than f...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2016.10.016
更新日期：2017-01-01 00:00:00
abstract：:We report the case of a 42-year-old non-smoking man, who had worked as a carpenter for 6 years and who reported a history of rhinorrhea, paroxysmal sneezing, nasocular pruritus, lacrimation, wheezing and dyspnea attacks while preparing a mixture to seal the junctures between wooden panels. Allergy study consisted of s...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(05)73251-1
更新日期：2005-11-01 00:00:00
abstract：:Sera from 19 patients with hypersensitivity pneumonitis induced by avian antigens were studied in order to determine the presence of circulating autoantibodies. IgM and IgG rheumatoid factors were positive in 68% and 100% of the cases respectively. IgM-rheumatoid factor was detected with at least two methods, showing ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Asthma morbidity and mortality have been increasing. Data of asthma and respiratory mortality rates in Brazil are scarse. METHODS:We studied asthma and respiratory disease mortality rates in the state of So Paulo (capital and country side) from 1970 to 1996, as its relation with sales of drugs usually used ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(02)79084-8
更新日期：2002-01-01 00:00:00
abstract：:Anaphylaxis is a systemic reaction which can be very dangerous in many patients. In addition to the most common antigens (drugs, venoms, foods), physical exercise can provoke anaphylaxis in the sensitized patients. The mechanism of this reaction is still unknown. In this report, we describe a case of exercise-induced ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
abstract：BACKGROUND:Since gamma interferon release assays (IGRAs) cannot differentiate between active tuberculosis and latent tuberculosis infection (LTBI), development of rapid and specific diagnosis tools are essential for discriminating between active tuberculosis (TB) from LTBI. Both IGRAs are based on Mycobacterium tubercu...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.09.004
更新日期：2016-07-01 00:00:00
abstract：:We report a case of nasal candidiasis in an immunocompetent host who denied the use of topical or systemic corticosteroids. The patient was treated with itraconazole 100 mg. with resolution of the symptoms. ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:Since the first decades of the twentieth century, some authors have believed bacterial respiratory infection to be an important triggering factor in bronchial asthma, drawing attention to an asthmatic response to infection. In this context, already in 1995, we presented a study on nasal secretion cultures and the rela...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/s0301-0546(01)79035-0
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:The sharon fruit is the edible fruit of the persimmon tree (Diospyros kaki) which belongs to the Ebenaceae family. There are few references of allergic reaction to this fruit. We introduce a case of a 33-years old man with a anaphylactic reaction immediately after ingestion of sharon fruit. METHODS:Skin pri...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(01)79021-0
更新日期：2001-03-01 00:00:00
abstract：:This study was motivated by the discrepancy in the results of published studies on the amount of histamine released following the intravascular administration of iodinated contrast media (ICM) in humans. From a group of patients due to undergo cardiac catheterization, we selected 45 subjects with no history of atopy. ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：:Serum zinc, copper and iron levels together with content of zinc in hair were investigated in 13 patients with common variable immunodeficiency (CVID) and in 13 controls. A significant decrease in serum zinc (mean = 11.3 mumol/l, SD = 2.9 in CVID patients compared to mean 14.3 mumol/l, SD = 2.4 in controls) and iron l...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1995-05-01 00:00:00
abstract：BACKGROUND:The prevalence of food allergy is on the rise on a global scale. OBJECTIVE:To determine the prevalence of food hypersensitivity (FHS) and probable food allergy (PFA), as well as the foods and factors associated with these occurrences. METHODS:A cross-sectional study was carried out among 1992 adolescents (...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2018.09.004
更新日期：2019-01-01 00:00:00
abstract：:Asthma morbidity and mortality has increased. One of the possible causes is the excessive use of beta agonists. The aim of this study is to compare the effects of six week treatment with beclomethasone alone (Ibec) or the combination of beclomethasone-salmeterol (Ibe + Isal) on serum potassium (K), CPK-MB and ECG in c...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0301-0546(01)79010-6
更新日期：2001-01-01 00:00:00
abstract：:This study investigated the specificity and efficacy of immunotherapy with Artemisia vulgaris (Artemisia) extract. We studied 25 patients with a more than two year lasting history of seasonal rhinoconjunctivitis and who had only two clinically important allergies, either to Artemisia and Betula verrucosa (Betula) or t...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-03-01 00:00:00
abstract：:Leguminous are a cheap source of protein that are cultivated practically throughout the world. They are the main source of food in developing countries. In the Mediterranean area and Middle East, the most commonly consumed legumes are lentils and chickpea. In the United States, United Kingdom and south-east Asia, the ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/s0301-0546(02)79152-0
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND:Yellow dye tartrazine is a potential cause of exacerbations of asthma, allergic rhinitis and urticaria in atopic patients. The Brazilian Sanitary Surveillance Agency (ANVISA) published a consultation about the possibility of issuing a label warning addressing these potential effects of food and drugs contain...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2009.09.009
更新日期：2010-05-01 00:00:00
abstract：:Clinical experience suggests that allergic signs and symptoms are more frequently observed in patients with systemic lupus erythematosus than in the general population. The aim of this paper was to evaluate the frequency of allergic clinical manifestations in systemic lupus erythematosus (SLE) by anamnesis. Sixty thre...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-07-01 00:00:00
abstract：OBJECTIVE:To investigate whether the genetic variants of TGFB1, TLE4, MUC22 and IKZF3 are associated with the development of asthma in Chinese children. METHODS:572 adolescent asthma patients and 590 age-matched healthy controls were included in this study. A total of four SNPs were genotyped, including rs2241715 of T...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2016.10.021
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:This study aimed to assess the regular use of long-term asthma-control medication and to determine inhaler techniques in asthmatic children. METHODS:The study was conducted on asthmatic children aged 6-18 years. Information on rescue and controller medications was given and the proper inhalation technique wa...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2019.06.009
更新日期：2020-01-01 00:00:00
abstract：:Numerous reports had been published implicating IPPD and other amine-type antioxidants as the causative agents in patients with allergic sensitization following the use of industrial and household products that have black rubber in their composition. The amine-type antioxidants, used to stabilize the polymer chains an...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:From October 1982 to July 1983, 133 consecutive patients complaining of allergic symptoms were prick-tested with three storage mites (Acarus siro, Lepidoglyphus destructor, Tyrophagus putrescentiae) and two housedust mites (Dermatophagoides pteronyssinus and Dermatophagoides farinae). A total of 60 patients (45%) had ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：:The aims of this report are: to investigate the kinetics of the E. coli lipopolysaccharide polyclonal response as a function of the background response, to test the capacity of lipopolysaccharide to activate presumably resting memory cells for IgM. Because mice do not produce a plaque-forming cell background against r...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：INTRODUCTION:Intravenous immunoglobulin (IVIG) therapy is an effective treatment in patients with different diseases. This product must comply with all the regulatory requirements established by the World Health Organization and the European Pharmacopoeia for clinical tolerance, therapeutic efficacy, and viral safety. ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13095871
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:To report the results of treatment with infliximab in patients with refractory juvenile idiopathic arthritis (JIA). PATIENTS AND METHODS:A prospective study of four children with refractory JIA was carried out. Infliximab (100 mg) was administered in weeks 0, 2 and 6. Subsequently, the drug was administered ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13101338
更新日期：2007-03-01 00:00:00
