Abstract:
:One hundred four consecutive men who underwent a semen analysis as part of their infertility evaluation were assayed for sperm-associated immunoglobulin (Ig) and the third component of complement (C3). Sixteen (15%) of the 104 men had increased IgG, and 10 (12%) of 86 men tested had increased IgA on their sperm; however, only 4 (5%) of the 87 men tested were positive for plasma IgG antisperm antibody. Only 2 (13%) of the 16 men with increased sperm-associated IgG had detectable IgG antisperm antibodies in their seminal plasma. Five (10%) of 50 men tested had increased sperm-associated C3; none had seminal plasma that deposited C3 on sperm. These data suggest that of the three compartments that can be tested--circulating plasma, seminal plasma, and the sperm surface--the direct measurement of sperm surface Ig may be most important in the evaluation of infertile men. The presence of sperm-associated IgG or IgA was not associated with semen abnormality. In contrast, the presence of sperm-associated IgG was associated with decreased mucus penetration at the time of postcoital testing despite normal-appearing mucus.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Haas GG Jr,Schreiber AD,Blasco Lsubject
Has Abstractpub_date
1983-04-01 00:00:00pages
542-7issue
4eissn
0015-0282issn
1556-5653pii
S0015-0282(16)46948-7journal_volume
39pub_type
杂志文章abstract:OBJECTIVE:To investigate the effects of thawing temperature on sperm function after cryopreservation. The technical aspects of sperm cryopreservation have significantly improved over the last few decades. However, a standard protocol designed to optimize sperm motility recovery after thawing has not yet been establishe...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.10.021
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To evaluate which clinical characteristics influence early maternal β-human chorionic gonadotropin (hCG) and progesterone levels in in vitro fertilization (IVF) pregnancies. DESIGN:Retrospective cohort analysis. SETTING:Academic medical center. PATIENT(S):Women with a live birth after single-blastocyst emb...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2018.08.047
更新日期:2018-12-01 00:00:00
abstract::After four unsuccessful attempts at multiple follicular induction with exogenous gonadotropins, a patient underwent two attempts at IVF in spontaneous cycles triggered with hCG. The second attempt resulted in the transfer of three embryos and a successful singleton intrauterine pregnancy. We believe that unstimulated ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)60746-x
更新日期:1989-06-01 00:00:00
abstract::The effect of six metabolically active compounds, namely caffeine, kallikrein, cyclic adenosine 3':5'-monophosphate, prostaglandin E, triiodothyronine, and insulin on spermatozoal motility was investigated. Hypokinetic and normokinetic semen specimens from fertile and infertile patients were incubated with various con...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract:OBJECTIVE:To determine accumulated conception and live birth rates in ovum donation. DESIGN:Retrospective study from a computer database. Pregnancies with one gestational sac observed by ultrasound have been included as conceptional cycles and pregnancies that resulted in one live child were recorded for the analysis ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)81372-6
更新日期:1997-04-01 00:00:00
abstract::The relaxin content of 92 normal semen samples and 85 semen samples selected at random was correlated to the parameters measured on routine semen analysis in those samples. The concentration of immunoactive relaxin in a sample of semen plasma did not correlate with any of the parameters commonly used for semen analysi...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)59130-4
更新日期:1987-04-01 00:00:00
abstract:OBJECTIVE:To compare ovarian response to hyperstimulation during IVF between patients who did and did not undergo salpingectomy. DESIGN:Meta-analysis. SETTING:University-affiliated teaching hospital. PATIENT(S):Patients undergoing IVF who did and did not undergo salpingectomy. INTERVENTION(S):None. MAIN OUTCOME ME...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.fertnstert.2016.03.053
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To describe a woman with blepharophimosis-ptosis-epicanthus inversus syndrome and hypergonadotropic hypogonadism. DESIGN:Case report. SETTING:University medical center. PATIENT(S):One 25-year-old woman. INTERVENTION(S):Pedigree, hormone assays, and donor embryo transfer. MAIN OUTCOME MEASURE(S):Pregnancy...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.07.1763
更新日期:2008-11-01 00:00:00
abstract::Chronic and transient hyperprolactinemia have been associated with luteal phase dysfunction in both spontaneously cycling women and those subjected to ovarian hyperstimulation by exogenous gonadotropins. It is the objective of the in vitro and in vivo studies reported herein to examine the possibility that prolactin (...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1987-07-01 00:00:00
abstract:OBJECTIVE:To investigate whether proteins secreted in urine differ between women with and without endometriosis. DESIGN:Laboratory study using human urine. SETTING:University-based laboratory. PATIENT(S):Women with and without endometriosis undergoing laparoscopy, hysteroscopy and curettage. INTERVENTION(S):Urine c...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.05.016
更新日期:2011-01-01 00:00:00
abstract::Danazol was found to possess androgenic and glucocorticoid activity in rat bioassays. In contrast, danazol displayed no significant estrogenic activity. In support of these findings, danazol bound to the 8 S androgen receptor of rat prostate cytosol and to the glucocorticoid receptor of rat liver cytosol, but danazol ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)43820-3
更新日期:1979-02-01 00:00:00
abstract:OBJECTIVE:To study attitudes about posthumous assisted reproduction (PAR) in individuals presenting for assisted reproduction, to examine the degree of concordance of attitudes within couples, and to determine whether individuals can accurately predict the attitudes of their intimate partners. DESIGN:Cross sectional s...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.09.018
更新日期:2011-12-01 00:00:00
abstract::The result of the hormone concentration of one blood sample was used to determine the accuracy of predicting not only the hormone concentrations of a second and third sample drawn 15 minutes apart, but also the mean value of the three samples. Three blood specimens from 73 men involved in two previously reported studi...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)59662-9
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:To investigate the use of preimplantation genetic diagnosis (PGD) as a method for increasing pregnancy success rates in patients at high risk for aneuploidy. DESIGN:Literature review and discussion of current evidence. CONCLUSION(S):Preimplantation genetic diagnosis selects euploid embryos for transfer in a...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2005.06.045
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To obtain proof-of-concept that locally produced anti-inflammatory steroids suppress ovulation-associated extracellular matrix proteases in human ovarian surface epithelial (OSE) cells. DESIGN:Primary OSE cell cultures treated with interleukin-1alpha (IL-1alpha) (500 pg/mL) as proxy for inflammation, with/wi...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.06.040
更新日期:2009-08-01 00:00:00
abstract::Activities of deoxyribonucleic acid (DNA) polymerase alpha, beta, and gamma were measured in extracts of testicular biopsy specimen obtained from 37 cases of male infertility with left varicocele and compared with those of 6 normal controls. It was observed that levels of DNA polymerase alpha, beta, and gamma were sig...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)60318-7
更新日期:1988-11-01 00:00:00
abstract::In a rat model, sodium carboxymethylcellulose (SCMC) was compared with normal saline and 32% dextran 70 in the prevention of surgically induced intraperitoneal adhesions. The 32% dextran 70 was similar to normal saline in the initial prevention of adhesions, and both appeared less effective than SCMC. After lysis of t...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)47910-0
更新日期:1984-06-01 00:00:00
abstract:OBJECTIVE:To determine whether obesity affects serum and seminal measures of male reproductive potential among a multi-institutional cohort. DESIGN:Retrospective multi-institutional cohort study. SETTING:Infertility clinics. PATIENT(S):All men referred for male infertility evaluation from 2002 to 2014 (n = 4,440). ...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2016.06.041
更新日期:2016-10-01 00:00:00
abstract::This study describes the results with immature human follicular oocytes harvested from unstimulated ovaries, matured in vitro, fertilized, and transferred to an agonadal recipient. Two hundred seventy immature oocytes were aspirated from 23 ovaries removed for various gynecological indications from August 1988 to Octo...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54068-0
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To develop a consensus regarding the need for luteal phase support during assisted reproductive technology (ART), and to establish the optimal compound and route of administration for this purpose. DESIGN:Review of the published literature on luteal phase support. PATIENT(S):Women undergoing assisted reprod...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(01)02961-2
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:To determine the effects of chilling on the organization and distribution of tubulin and chromosomes in rhesus monkey oocytes. DESIGN:Comparative laboratory study. SETTING:Academic research laboratory. ANIMAL(S):Eight adult female rhesus monkeys (Macaca mulatta) aged 6-16 years. INTERVENTION(S):A total of...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)03240-x
更新日期:2002-04-01 00:00:00
abstract::In this prospective study, we compared the results of bilateral varicocelectomy and left varicocelectomy for treatment of infertile patients with subclinical right and clinical left varicoceles with oligoasthenospermia. Because there was more improvement in semen parameters and pregnancy rate in patients who underwent...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.05.069
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:To create, validate, and use a fertility awareness survey based on current U.S. DATA: DESIGN:Cross-sectional study. SETTING:Not applicable. PATIENT(S):Phase 1 included U.S. women ages 18-45; phase 2 included female medical students and obstetrics and gynecology trainees at two urban academic programs. IN...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2017.07.1158
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To improve posttransplantation survival of frozen-thawed human ovarian tissue in immunodeficient mice. DESIGN:Histologic study of transplanted human ovaries after treating the host and graft. SETTING:Infertility unit, university-affiliated tertiary medical center. PATIENT(S):Ovarian tissue from six girls/w...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.07.1082
更新日期:2011-03-15 00:00:00
abstract:OBJECTIVE:To investigate whether components of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway are present and active in human sperm. DESIGN:Comparative study. SETTING:Reproductive biology department. PATIENT(S):Nine sperm donors. INTERVENTION(S):Sperm were exposed to interfer...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)01896-9
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVE:To assess whether heart rate variability (HRV) at rest and during sympathetic stimulation is disturbed in patients with different polycystic ovary syndrome (PCOS) phenotypes in comparison to healthy controls. DESIGN:Cross-sectional study. SETTING:University hospital. PATIENT(S):Thirty women with classic, a...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2012.08.049
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To assess the association between recent cigarette smoking (CS) in female and male partners and assisted reproduction technology (ART) outcomes. DESIGN:Cohort prospective study. SETTING:University ART program in Chile. PATIENT(S):One hundred sixty-six couples seeking pregnancy through ART. INTERVENTION(S)...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.09.073
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To define a therapeutic strategy adapted to acute urine retention resulting from uterine incarceration in early pregnancy. DESIGN:Case report and review of the literature. SETTING:University hospital. PATIENT(S):Two cases of acute urine retention induced by severe fibroid incarceration in first trimester. ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2007.10.008
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:To develop molecular tools increasing the sensitivity of breast cancer micrometastases detection within ovarian tissue cryopreserved for fertility preservation. DESIGN:Expression of breast markers was evaluated by quantitative polymerase chain reaction in ovarian tissue from patients with benign or cancerous...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.04.036
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To evaluate surgical sperm retrieval rates in adolescents with Klinefelter syndrome and testosterone replacement therapy (TRT). DESIGN:Case series. SETTING:Academic medical center. PATIENT(S):Ten patients with Klinefelter syndrome, aged 14-22 years, treated with testosterone replacement and aromatase inhib...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.06.010
更新日期:2013-10-01 00:00:00