Abstract：
:Convergence of cardiac and cutaneous afferents onto neurons in the dorsal horn of the spinal cord was demonstrated in the cat. Responses of neurons to cutaneous stimulation revealed that they were either nociceptive specific (NS) or wide dynamic range (WDR) neurons. NS neurons were located in lamina I and outer zone of lamina II (IIo). WDR neurons were located in laminae I and IIo as well as laminae IV-VI. Since all the neurons responsive to electrical stimulation of the inferior cardiac nerve responded to cutaneous nociceptive input, it was inferred that the sensation evoked by excitation of dorsal horn neurons by cardiac afferents is pain. The observed convergence is suggested as a mechanism for referred pain, and convergence onto WDR neurons provides an explanation for the phenomenon of allodynia in a stage between anginal attacks.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Takahashi M,Yokota Tdoi
10.1016/0304-3940(83)90377-4subject
Has Abstractpub_date
1983-08-08 00:00:00pages
251-6issue
3eissn
0304-3940issn
1872-7972pii
0304-3940(83)90377-4journal_volume
38pub_type
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.01.006
更新日期：2008-03-15 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2010.11.050
更新日期：2011-01-25 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2006-08-07 00:00:00
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
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更新日期：2016-03-11 00:00:00
