Comparison of the killer toxin of several yeasts and the purification of a toxin of type K2.

Abstract:

:A total of 13 killer toxin producing strains belonging to the genera Saccharomyces, Candida and Pichia were tested against each other and against a sensitive yeast strain. Based on the activity of the toxins 4 different toxins of Saccharomyces cerevisiae, 2 different toxins of Pichia and one toxin of Candida were recognized. The culture filtrate of Pichia and Candida showed a much smaller activity than the strains of Saccharomyces. Extracellular killer toxins of 3 types of Saccharomyces were concentrated and partially purified. The pH optimum and the isoelectric point were determined. The killer toxins of S. cerevisiae strain NCYC 738, strain 399 and strain 28 were glycoproteins and had a molecular weight of Mr = 16,000. The amino acid composition of the toxin type K2 of S. cerevisiae strain 399 was determined and compared with the composition of two other toxins.

journal_name

Arch Microbiol

journal_title

Archives of microbiology

authors

Pfeiffer P,Radler F

doi

10.1007/BF00410734

subject

Has Abstract

pub_date

1984-04-01 00:00:00

pages

357-61

issue

4

eissn

0302-8933

issn

1432-072X

journal_volume

137

pub_type

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