Genetic control of lysine permeases in Saccharomycopsis lipolytica.

Abstract:

:In order to obtain strains of Saccharomycopsis lipolytica impaired in the active transport of L-lysine, mutants resistant to a mixture of L-canavanine, L-4-5-transdehydrolysine and L-S-amino ethylcysteine, taken either all three or two by two, were isolated. These compounds were shown previously to be competitive inhibitors of L-lysine uptake. The resistance patterns and excretion capacity of the mutants were established. All mutants behaved as monogenic. Recombination tests indicated that four genes at least were involved. All mutants were impaired in both high and low affinity L-lysine transport systems. Several hypotheses on the functions of these genes are put forward and discussed.

journal_name

Arch Microbiol

journal_title

Archives of microbiology

authors

Beckerich JM,Lambert M,Heslot H

doi

10.1007/BF00411361

subject

Has Abstract

pub_date

1979-08-06 00:00:00

pages

201-5

issue

2

eissn

0302-8933

issn

1432-072X

journal_volume

122

pub_type

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