Abstract：
:The reaction of nerve endings in the median eminence of the rat to zinc iodide-osmium tetroxide (ZIO) staining was examined electron microscopically under normal and experimental conditions. The experimental condition of catecholamine exhaustion in the nerve endings was induced by the administration of H44/68 and reserpine. Vesicles in the terminals of catecholaminergic nerves reacted similarly to ZIO staining in both normal and experimental material. The majority of synaptic vesicles in various terminals gave a positive ZIO reaction. The neurosecretory elementary granules, however, failed to react with ZIO. On the other hand, some nerve terminals in the external layer of the median eminence showed a strong positive reaction in the cytoplasmic matrix, in mitochondria as well as in synaptic vesicles. These findings strongly suggest that the ZIO-positive substance in nerve terminals is not the transmitter itself, i.e. the monoamine, but rather represents a range of substances commonly found in various kinds of synaptic vesicles and is probably proteinaceous in nature. A brief discussion is also given on the difference in ZIO reactivity between neurosecretory elementary granules and small vesicles in the hypothalamo-hypophyseal tract.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Matsuura T,Ibata Y,Sano Ydoi
10.1007/BF00220316subject
Has Abstractpub_date
1976-10-13 00:00:00pages
279-86issue
3eissn
0302-766Xissn
1432-0878journal_volume
173pub_type
杂志文章abstract：:The muscle cells of the ventricle, the branchial heart and the branchial heart appendages of Rossia macrosoma (Delle Chiaje) are studied. The ventricle myocardium has three muscle layers, while the other two organs exhibited a loose arrangement of muscle cells. The muscle cells of the ventricle, the branchial heart an...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：
更新日期：1977-12-13 00:00:00
abstract：:Light microscopy of native preparations, histology, and electron microscopy have revealed that Phlebotomus duboscqi belongs to a class of sand fly species with prompt development of the peritrophic matrix (PM). Secretion of electron-lucent fibrils, presumably chitin, starts immediately after the ingestion of a blood m...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0802-1
更新日期：2009-08-01 00:00:00
abstract：:The distribution of the glycoprotein, mucin 1 (MUC1), was determined in lactating guinea-pig mammary tissue at the resolution of the electron microscope. MUC1 was detected on the apical plasma membrane of secretory epithelial cells, the surface of secreted milk-fat globules, the limiting membranes of secretory vesicle...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410100351
更新日期：2001-04-01 00:00:00
abstract：:Among heterogeneous S100β-protein-positive (S100β-positive) cells, star-like cells with extended cytoplasmic processes, the so-called folliculo-stellate cells, envelop hormone-producing cells or interconnect homophilically in the anterior pituitary. S100β-positive cells are known, from immunohistochemistry, to emerge ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2256-y
更新日期：2016-02-01 00:00:00
abstract：:Tight junctions (TJ) between retinal pigmented epithelial (RPE) and retinal endothelial cells maintain the outer and inner blood-retinal barrier, and the breakdown of these barriers is associated with retinal diseases. Vascular endothelial growth factor (VEGF) increases vascular permeability and is thought to be invol...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0046-7
更新日期：2006-01-01 00:00:00
abstract：:Olfactory marker protein (OMP) was first described as a protein expressed in olfactory receptor neurons (ORNs) in the nasal cavity. In particular, OMP, a small cytoplasmic protein, marks mature ORNs and is also expressed in the neurons of other nasal chemosensory systems: the vomeronasal organ, the septal organ of Mas...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-020-03349-9
更新日期：2021-01-15 00:00:00
abstract：:The oxyntic mucosa of the mammalian stomach is rich in endocrine cells, such as ECL cells, A-like cells, somatostatin cells, D1/P cells and, in some species, enterochromaffin cells. The various endocrine cell types can be distinguished on the basis of their characteristic cytoplasmic granules and vesicles. The ECL cel...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050707
更新日期：1996-12-01 00:00:00
abstract：:The effect of pilocarpine and food uptake on the rate of incorporation of [3H]-leucine in vivo was measured by means of quantitative radioautography in three exocrine cells of the rat: the acinar and the granular duct cells of the submandibular and the acinar cells of the parotid gland. The three cell types react diff...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219936
更新日期：1975-12-18 00:00:00
abstract：:Evidence has already been adduced suggesting that an increase in microtubular number occurs in the tractus hypophyseus of rats stressed by the administration of hypertonic saline, and of rats with congenital diabetes insipidus (CDI). Since the tractus hypophyseus in these animals shows high secretory activity, it seem...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219611
更新日期：1976-06-28 00:00:00
abstract：:The afferent lymphatic vessels of rat popliteal lymph nodes were interrupted, and the histological alterations in the lymph nodes occurring 1 to 14 weeks after operation were studied. One week after operation the number of macrophages was considerably reduced and continued to decrease during the subsequent time period...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234394
更新日期：1980-01-01 00:00:00
abstract：:To gain a better understanding of the neuroplasticity of sympathetic neurons during postnatal ontogenesis, the distribution of neuronal nitric oxide synthase (nNOS) immunoreactivity was studied in sympathetic preganglionic neurons (SPN) in the spinal cord (Th2 segment) of female Wistar rats at different ages (newborn,...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2925-8
更新日期：2019-02-01 00:00:00
abstract：:Apoptotic and inflammatory processes occur in human arteriosclerotic lesions. We examined the hypothesis whether both processes are possibly associated by studying the colocalization of corresponding markers. In 11 human arteriosclerotic carotid arteries, proapoptotic markers (CPP32 (caspase-3), poly(ADP-ribose) polym...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0024-0
更新日期：2005-12-01 00:00:00
abstract：:We have examined IgG Fc receptor (FcR) activity of human and rabbit arachnoid granulations and leptomeninges using antibody (IgG)-coated erythrocytes (EIgG), covalently crosslinked IgG dimers, trimers and oligomers, immune complexes, aggregated Fc fragments and a monoclonal anti-human neutrophil Fc receptor antibody, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216489
更新日期：1987-06-01 00:00:00
abstract：:Rat blood monocytes contain granules of two types, primary and secondary granules, which can be distinguished on morphological grounds. Secondary granules have a halo between the limiting membrane and the matrix; primary granules have no halo and are generally more elongate than the secondary granules. In addition, th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00226665
更新日期：1977-11-30 00:00:00
abstract：:The use of antibodies to alpha-(17--39) ACTH, beta-LPH, and alpha- and beta-endorphins has enabled the detection of immunoreactive cells as early as the eight week of fetal life. Immunoreactive cells are located in the anterior and intermediate lobes of the pituitary gland in normal human fetuses. The same cells react...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00225339
更新日期：1978-10-30 00:00:00
abstract：:The ultrastructure of the contractile apparatus of the rat soleus muscle during the course of denervation atrophy was investigated. It was found that the ratio of thin the thick filaments increased in myofibrils of atrophying muscle fibers. Elevation of the ratio was observed as early as the second day after denervati...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216767
更新日期：1981-01-01 00:00:00
abstract：:The spermatogonial stem cell line in prepubertal and adult bovine testis was studied by electron microscopy and protein gene product 9.5 immunohistochemistry. Three successive spermatogonia precursor cell configurations were observed. Small basal stem cells were found to possess a spherical shape and nuclei with two t...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00583394
更新日期：1995-08-01 00:00:00
abstract：:The presence of immunoreactive enkephalin, dynorphin, vasoactive intestinal polypeptide, cholecystokinin, substance P and neuropeptide Y in nerve fibers that project to the guinea-pig inferior mesenteric ganglion was analysed, after different denervation and ligation procedures. A quantitative analysis demonstrates th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219741
更新日期：1988-09-01 00:00:00
abstract：:The expression of nicotinic acetylcholine receptors (nAChR) in fetal lung suggests maternal smoking during pregnancy effects newborn lung structure and function by the direct interaction of nicotine with nAChR in the developing lung. The recent identification of the lynx1 nAChR modulator protein in nicotinic neurons i...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1077-9
更新日期：2005-05-01 00:00:00
abstract：:The technique of cobalt sulfide precipitation combined with Timm's sulfide-silver method for intensification of heavy metals was used to delineate the retino-hypothalamic projection of the rat. Freshly isolated rat brains were dissected and a solution of cobaltous chloride was applied to one of the cut optic nerves. S...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219728
更新日期：1976-04-28 00:00:00
abstract：:Prostatic carcinoma affects 1 in 11 men and targets bone with sclerotic metastases. The study of prostate carcinoma growth in bone has been hampered by the lack of suitable animal models. We have developed an in vivo model of prostate carcinoma growth in bone by inoculating three human prostate carcinoma cell lines (P...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-001-0503-x
更新日期：2002-03-01 00:00:00
abstract：:Dexamethasone (Dex) regulates osteoblastic and adipocytic differentiation in mesenchymal progenitor cells through regulation of Wnt/β-catenin signaling. To elucidate the regulatory mechanisms underlying the effects of Dex, we examine the expression of Axin2, which is an intracellular inhibitor of Wnt/β-catenin signali...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1696-5
更新日期：2013-12-01 00:00:00
abstract：:The tyrosine kinase proteins (Trk), encoded by the trk family of proto-oncogenes, mediate, in mammals, the action of neurotrophins, a family of growth factors acting on the development and maintenance of the nervous system. Neurotrophins and their specific receptors, TrkA, TrkB and TrkC, seem to be phylogenetically we...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000342
更新日期：2001-03-01 00:00:00
abstract：:Neural stem cells (NSCs) are a subtype of tissue-specific progenitor cells capable of extended self-renewal and the ability to generate all major cell types of nervous tissue, such as neurons, astroglia and oligodendroglial cells. Recent studies suggest that salient patterning in anterior-posterior and dorsal-ventral ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-004-0923-5
更新日期：2004-10-01 00:00:00
abstract：:The submandibular gland (SMG) of newborn mice has no mature acini but has the rudiments of acini called terminal tubules (TT). The TT are composed of TT cells with dark secretory granules and proacinar cells with lighter secretory granules, the latter being considered the immediate precursor of mature acinar cells. TT...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03205-w
更新日期：2020-08-01 00:00:00
abstract：:The monoamines octopamine and tyramine, which are the invertebrate counterparts of epinephrine and norepinephrine, transmit their action through sets of G protein-coupled receptors. Four different octopamine receptors (Oamb, Octß1R, Octß2R, Octß3R) and 3 different tyramine receptors (TyrR, TyrRII, TyrRIII) are present...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2137-4
更新日期：2015-09-01 00:00:00
abstract：:In the atherosclerotic plaque, smooth muscle cells (SMC) acquire an inflammatory phenotype. Resistin and fractalkine (CX3CL1) are found in human atheroma and not in normal arteries. CX3CL1 and CX3CR1 are predominately associated with SMC. We have questioned whether resistin has a role in the expression of CX3CL1 and C...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-012-1510-9
更新日期：2013-01-01 00:00:00
abstract：:In the present study, we used ultrastructural cytochemistry to analyze the distribution of nuclear and cytoplasmic nucleic acids and polysaccharides, and electron spectroscopic imaging to map the element phosphorus in immature erythroid cells taken from two amphibians, the diploid Bufo ictericus and the tetraploid Odo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305791
更新日期：1994-10-01 00:00:00
abstract：:Whether an axon will regenerate after it is cut depends on the balance between the intrinisic ability of the axon to regrow and the permissiveness of the environment surrounding it. The permissiveness of the environment is determined by the glial cells at the site of injury, and in the CNS both oligodendrocytes and as...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410050943
更新日期：1997-11-01 00:00:00
abstract：:The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that have been implicated in both receptor and store-operated channel functions. The family of the classical TRPs (TRPCs) consists of seven members (TRPC1-7). The presence of TRPC1 and TRPC5 mRNA in the brain has prev...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0004-4
更新日期：2005-11-01 00:00:00
