Abstract：
:A membrane receptor protein for asialoglycoproteins induces voltage-dependent increases in ion conductance across a lipid bilayer, probably reflecting penetration of the protein into the bilayer towards an electrically positive pole. In the presence of specific ligand for the receptor, this penetration leads to a 'translocation' of the receptor from one side of the bilayer to the other. These observations suggest a mechanism by which biological membranes might regulate the disposition of their proteins, and a way in which membrane receptors involved in endocytosis might be spared lysosomal destruction in order to be recycled to the plasma membrane.
journal_name
Naturejournal_title
Natureauthors
Blumenthal R,Klausner RD,Weinstein JNdoi
10.1038/288333a0subject
Has Abstractpub_date
1980-11-27 00:00:00pages
333-8issue
5789eissn
0028-0836issn
1476-4687journal_volume
288pub_type
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