Effects of age and diabetes mellitus on cyanogen bromide digestion of human dura mater collagen.

abstract：:Quantitative levels of mRNAs coding for elastin, types I and III procollagen and gamma-actin were measured in porcine vascular material following balloon catheterization. A balloon catheter was introduced into the thoracic aorta and jugular vein of 3-6 week old pigs; following distention and six days of postoperative ...

journal_title：Connective tissue research

authors： Boyd CD,Kniep AC,Pierce RA,Deak SB,Karboski C,Miller DC,Parker MI,Mackenzie JW,Rosenbloom J,Scott GE

更新日期：1988-01-01 00:00:00

abstract：:X-Ray diffraction and scanning electron microscopy show that collagen fibrils tend to be oriented parallel to the surface of the vertebral end plates in pig, rat and man. It is suggested that this orientation allows the end plate to withstand the pressure exerted on it by the nucleus pulposus. Scanning electron micros...

journal_title：Connective tissue research

authors： Aspden RM,Hickey DS,Hukins DW

更新日期：1981-01-01 00:00:00

abstract：:Human aortic smooth muscle cells (AoSMCs) change their extracellular matrix composition during aging, with direct effects on cellular events and cell migration. For example, active matrix metalloproteinase-2 (MMP-2) is synthesized only by young AoSMCs, whereas aged cells produce only the inactive zymogen form. The pro...

journal_title：Connective tissue research

authors： Vigetti D,Moretto P,Viola M,Genasetti A,Rizzi M,Karousou E,Clerici M,Bartolini B,Pallotti F,De Luca G,Passi A

更新日期：2008-01-01 00:00:00

abstract：:Hall type voltage has been observed in bone and its two major components (collagen and apatite) in the region of moderately high electric and magnetic fields. The configuration of the sample placement and the experimental set up was the same as that adopted in standard Hall measurements. The resistivity of the sample ...

journal_title：Connective tissue research

authors： Behari J,Andrabi WH

更新日期：1978-01-01 00:00:00

abstract：:Osteoarthritis (OA), the most common form of degenerative joint disease, is linked to high morbidity. It is predicted to be the single greatest cause of disability in the general population by 2030. The development of disease-modifying therapy for OA currently face great obstacle mainly because the onset and developme...

journal_title：Connective tissue research

authors： Wei Y,Bai L

更新日期：2016-07-01 00:00:00

abstract：:Heparin treated and aldehyde crosslinked rat aorta segments were implanted in infrarenal aorta of homologous rats. One year following aortic replacement, the subendothelial scar and the prosthetic remnants were excised. The scar and the host intima-media were incubated with 3H-valine for 4 h and extracted with 5 M gua...

journal_title：Connective tissue research

authors： Moczar M,Bessou JP,Loisance D

更新日期：1983-01-01 00:00:00

abstract：OVERVIEW:Periostin (POSTN) is critical to bone and dental tissue morphogenesis, postnatal development, and maintenance; however, its roles in tissue repair and regeneration mediated by human periodontal ligament mesenchymal stem cells (PDLSCs) remain unclear. The present study was designed to evaluate the effects of PO...

journal_title：Connective tissue research

authors： Wu Z,Dai W,Wang P,Zhang X,Tang Y,Liu L,Wang Q,Li M,Tang C

更新日期：2018-03-01 00:00:00

abstract：:Depolymerization of Ch-4-S, Ch-6-S, HA and HP was observed by gel filtration after treatment with 2-10 N NaOH or Ba(OH)2 in the presence of NaBH4 at 80-83 degrees for 1-5 hr. Depolymerized products were isolated after these treatments. 4-Deoxy-alpha-L-threo-4-enohexopyranosyluronic acid residue as the nonreducing end ...

journal_title：Connective tissue research

authors： Hirano S,Ishigami M,Koga Y

更新日期：1975-01-01 00:00:00

abstract：:Purpose/Aim: Knee meniscus is a wedge-shaped fibrocartilaginous tissue, playing important roles in maintaining joint stability and function. Injuries to the meniscus, particularly with the avascular inner third zone, hardly heal and frequently progress into structural breakdown, followed by the initiation of osteoarth...

journal_title：Connective tissue research

authors： Tarafder S,Park G,Lee CH

更新日期：2020-05-01 00:00:00

abstract：:The effects of two forms of elastase on the Young's Modulus of elastic tissue have been studied. The monomeric, calcium poor form of the enzyme lowers the value of the Young's Modulus before an appreciable amount of protein is taken into solution. The polymeric, calcium rich enzyme on the other hand degrades the prote...

journal_title：Connective tissue research

authors： Hall DA

更新日期：1976-01-01 00:00:00

abstract：:The meniscal cartilages in the knee function to improve congruity of the medial and lateral femoro-tibial joints and play critical roles in load distribution and joint stability. Meniscal tears of various configurations are one of the most common conditions of the knee and are associated with an increased risk of deve...

journal_title：Connective tissue research

authors： Melrose J,Fuller ES,Little CB

更新日期：2017-01-01 00:00:00

abstract：:The majority of patients eligible for periodontal regenerative therapies are aged subjects. Since periodontal ligament cells (PDLC) are essential for periodontal regeneration, the aim of the present study was to determine the effect of cellular aging on PDLC, including genes associated with extracellular matrix metabo...

journal_title：Connective tissue research

authors： Benatti BB,Silvério KG,Casati MZ,Sallum EA,Nociti FH Jr

更新日期：2008-01-01 00:00:00

abstract：:An extensive literature on bone morphogenetic protein (BMP) induced generation and regeneration shows general agreement about one observation. The incidence and quantity of bone were greatest when BMP was delivered with a carrier of various biologic and non biologic polymers. In the present research, neutral lipids ei...

journal_title：Connective tissue research

authors： Urist MR,Behnam K,Kerendi F,Raskin K,Nuygen TD,Shamie AN,Malinin TI

更新日期：1997-01-01 00:00:00

abstract：:A method is described for accurate and reproducible determination of wet and dry weights of small articular cartilage samples. The water content of the articular cartilage samples before and after treatment with selective degradative enzymes and "artificial fibrillation" was determined. It was found that the water con...

journal_title：Connective tissue research

authors： Simon WH,Wohl DL

更新日期：1982-01-01 00:00:00

abstract：:Although fibronectin (FN) modified by advanced glycation end products (AGEs) has been shown to contribute to the development of diabetic vascular complications through its reduced adhesive activity to vascular cells, little is known about changes in the cell binding domain of AGE-modified FN. Here we examined the mech...

journal_title：Connective tissue research

authors： Sakata N,Sasatomi Y,Meng J,Ando S,Uesugi N,Takebayashi S,Nagai R,Horiuchi S

更新日期：2000-01-01 00:00:00

abstract：:Syndecan-4 is emerging as an important player in cell interaction with the extracellular environment and has been shown to be involved in the progression of intervertebral disc degeneration. However, the mechanism of syndecan-4 regulation by TNF-α and the role of TGF-β1 in regulating syndecan-4 expression remain poorl...

journal_title：Connective tissue research

authors： Yang H,Liu H,Li X,Pan H,Li Z,Wang J,Zheng Z

更新日期：2015-01-01 00:00:00

abstract：:Abnormal polyanion metabolism in cultured fibroblasts from patients with pseudoxanthoma elasticum (PXE) was studied by incubating normal and PXE fibroblasts in culture medium containing 35SO4 for 96 hr and measuring differences in secreted 35SO4-labelled proteoglycans (35S-PG). PXE medium contained less high molecular...

journal_title：Connective tissue research

authors： Gordon SG,Overland M,Foley J

更新日期：1978-01-01 00:00:00

abstract：:Purpose/Aim: Elevated serum phosphate is one of the major factors contributing to vascular calcification. Studies suggested that extracellular vesicles released from vascular smooth muscle cells significantly contribute to the initiation and progression of this pathology. Recently, we have demonstrated that elevated p...

journal_title：Connective tissue research

authors： Chaudhary SC,Khalid S,Smethurst V,Monier D,Mobley J,Huet A,Conway JF,Napierala D

更新日期：2018-12-01 00:00:00

abstract：:Radiation therapy is one of the routine treatment modalities for cancer patients. Ionizing radiation (IR) can induce bone loss, and consequently increases the risk of fractures with delayed and nonunion of the bone in the cancer patients who receive radiotherapy. The orchestrated bone remodeling can be disrupted due t...

journal_title：Connective tissue research

authors： Zhang J,Qiu X,Xi K,Hu W,Pei H,Nie J,Wang Z,Ding J,Shang P,Li B,Zhou G

更新日期：2018-11-01 00:00:00

abstract：:Odontogenesis involves a complex series of processes including epithelial-mesenchymal interactions, morphogenesis, differentiation, fibrillogenesis, and mineralization. Extracellular (ECM) remodeling plays a critical role in the rapid morphological changes that accompany these events. It is proposed that matrix metall...

journal_title：Connective tissue research

authors： Randall LE,Hall RC

更新日期：2002-01-01 00:00:00

abstract：:The mineralized matrices of enamel, cementum, dentin, calcified cartilage and bone are similar in their ability to form a microenvironment that facilitates deposition of hydroxyapatite. However, they are not identical, as witnessed by the nature of apatite crystals that are formed. Enamel is devoid of collagen; and is...

journal_title：Connective tissue research

authors： Robey PG

更新日期：1996-01-01 00:00:00

abstract：:The novel method of high voltage electron microscopic tomography (3D) has been applied for the first time to examine ultrastructural features and spatial relations between collagen fibrils and mineral crystals in a mouse mutant (oim/oim) which replicates a moderate to severe form of osteogenesis imperfecta. The animal...

journal_title：Connective tissue research

authors： Landis WJ

更新日期：1995-01-01 00:00:00

abstract：:The small leucine-rich repeat proteoglycans (SLRPs) constitute a group of structurally and functionally related molecules that participate in the organization of the extracellular matrix ECM and have important effects on cell behavior. Osteosarcomas are heterogeneous bone tumors whose common characteristic is the prod...

journal_title：Connective tissue research

authors： Nikitovic D,Berdiaki K,Chalkiadaki G,Karamanos N,Tzanakakis G

更新日期：2008-01-01 00:00:00

abstract：:Bone and dentin contain many phosphoproteins in their extracellular matrix. It has been postulated that the anionic character of these proteins, and the presence of phosphate groups in particular, is important for various functions related to biomineralization. Phosphophoryns (PP), are the most highly phosphorylated d...

journal_title：Connective tissue research

authors： Sfeir C,Veis A

更新日期：1996-01-01 00:00:00

abstract：:The biological effects of isolated soluble dentin extracellular matrix components on the induction of reparative dentinogenesis in exposed cavities in ferret canine teeth have been shown to be blocked by immobilizing the extracellular matrix components on nitrocellulose or Millipore membranes during implantation. This...

journal_title：Connective tissue research

authors： Smith AJ,Tobias RS,Cassidy N,Bégue-Kirn C,Ruch JV,Lesot H

更新日期：1995-01-01 00:00:00

abstract：:Purpose: In experimental models of equine joint-injury and osteoarthritis synovial fluid (SF) composition (proteoglycan-4, hyaluronan) can vary, along with changes to SF mechanical function (lubrication, viscosity). The study hypotheses were a) clinical equine joint-injury and disease results in altered SF composition...

journal_title：Connective tissue research

authors： Matheson A,Regmi SC,Martin-Alarcon L,Jay GD,Scott WM,Schmidt TA

更新日期：2020-04-20 00:00:00

abstract：:The crystal ghosts represent a crystal associated organic material which is stained by acidic phosphotungstic acid, periodic acid-silver methenamine and periodic acid-thiosemicarbazide-osmium, and is reactive with cations and with colloidal iron at pH 2.0, and unreactive after methylation and saponification. These res...

journal_title：Connective tissue research

authors： Bonucci E,Silvestrini G,di Grezia R

更新日期：1989-01-01 00:00:00

abstract：:For many years we have investigated the earliest crystal formations of different developing hard tissues (matrix vesicle, bone, dentine, enamel, etc.) by different electron microscopic measurements. It was observed that primarily Ca-phosphate (apatite) "chains," composed of nanometer sized particles (dots, islands), e...

journal_title：Connective tissue research

authors： Höhling HJ,Arnold S,Barckhaus RH,Plate U,Wiesmann HP

更新日期：1995-01-01 00:00:00

abstract：:Bone sialoprotein is a 34 kDa phosphorylated and sulphated glycoprotein that is essentially unique to mineralizing connective tissues. Recent studies on the developmental expression of BSP mRNA and the temporo-spatial appearance of the protein during bone formation in vivo and in vitro have demonstrated that BSP is ex...

journal_title：Connective tissue research

authors： Sodek J,Li JJ,Kim RH,Ogata Y,Yamauchi M

更新日期：1996-01-01 00:00:00

abstract：:Effects of applied hydrostatic pressure on transmembrane potentials were investigated in sheep articular chondrocytes and human skin fibroblasts in non-confluent monolayer cultures. Resting potentials in chondrocytes (about -12 mv) and in fibroblasts (about -15 mV) were increased and decreased respectively by over 40%...

journal_title：Connective tissue research

authors： Wright MO,Stockwell RA,Nuki G

更新日期：1992-01-01 00:00:00