Identifier sequences are transcribed specifically in brain.

abstract：:In order to understand the dynamics of the India Asia collision zone, it is important to know the strain distribution in Central Asia, whose determination relies on the slip rates for active faults. Many previous slip-rate estimates of faults in Central Asia were based on the assumption that offset landforms are young...

journal_title：Nature

authors： Hetzel R,Niedermann S,Tao M,Kubik PW,Ivy-Ochs S,Gao B,Strecker MR

更新日期：2002-05-23 00:00:00

abstract：:Change history: In Fig. 1c of this Letter, the two graphs were duplicates. The right panel of Fig. 1c has been corrected online. ...

journal_title：Nature

authors： Lai B,Gao W,Cui K,Xie W,Tang Q,Jin W,Hu G,Ni B,Zhao K

更新日期：2018-12-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature

authors： Cai W,Ng B,Geng T,Wu L,Santoso A,McPhaden MJ

更新日期：2020-12-01 00:00:00

abstract：:Dynein and its cofactor dynactin form a highly processive microtubule motor in the presence of an activating adaptor, such as BICD2. Different adaptors link dynein and dynactin to distinct cargoes. Here we use electron microscopy and single-molecule studies to show that adaptors can recruit a second dynein to dynactin...

journal_title：Nature

authors： Urnavicius L,Lau CK,Elshenawy MM,Morales-Rios E,Motz C,Yildiz A,Carter AP

更新日期：2018-02-07 00:00:00

abstract：:Quantum computation, a paradigm of computing that is completely different from classical methods, benefits from theoretically proved speed-ups for certain problems and can be used to study the properties of quantum systems1. Yet, because of the inherently fragile nature of the physical computing elements (qubits), ach...

journal_title：Nature

authors： Kandala A,Temme K,Córcoles AD,Mezzacapo A,Chow JM,Gambetta JM

更新日期：2019-03-01 00:00:00

abstract：:A connection between thunderstorms and the ionosphere has been hypothesized since the mid-1920s. Several mechanisms have been proposed to explain this connection, and evidence from modelling as well as various types of measurements demonstrate that lightning can interact with the lower ionosphere. It has been proposed...

journal_title：Nature

authors： Davis CJ,Johnson CG

更新日期：2005-06-09 00:00:00

abstract：:RNA is involved in many biological functions, ranging from information storage and transfer to the catalysis of reactions involving both nucleic acids and proteins. Previous crystallographic studies on RNA oligomeric chains provide only averaged structures or information limited in resolution. The oligomer [U(U-A)6A]2...

journal_title：Nature

authors： Dock-Bregeon AC,Chevrier B,Podjarny A,Moras D,deBear JS,Gough GR,Gilham PT,Johnson JE

更新日期：1988-09-22 00:00:00

abstract：:Ultrathin ferroelectric materials could potentially enable low-power perovskite ferroelectric tetragonality logic and nonvolatile memories1,2. As ferroelectric materials are made thinner, however, the ferroelectricity is usually suppressed. Size effects in ferroelectrics have been thoroughly investigated in perovskite...

journal_title：Nature

authors： Cheema SS,Kwon D,Shanker N,Dos Reis R,Hsu SL,Xiao J,Zhang H,Wagner R,Datar A,McCarter MR,Serrao CR,Yadav AK,Karbasian G,Hsu CH,Tan AJ,Wang LC,Thakare V,Zhang X,Mehta A,Karapetrova E,Chopdekar RV,Shafer P,Arenh

更新日期：2020-04-01 00:00:00

abstract：:Homoiotherms, for example mammals, regulate their body temperature with physiological responses such as a change of metabolic rate and sweating. In contrast, the body temperature of poikilotherms, for example Drosophila, is the result of heat exchange with the surrounding environment as a result of the large ratio of ...

journal_title：Nature

authors： Hong ST,Bang S,Hyun S,Kang J,Jeong K,Paik D,Chung J,Kim J

更新日期：2008-08-07 00:00:00

abstract：:The cloning and characterization of 'clock gene' families has advanced our understanding of the molecular control of the mammalian circadian clock. We have analysed the human genome for additional relatives, and identified new candidate genes that may expand our knowledge of the molecular workings of the circadian clo...

journal_title：Nature

authors： Clayton JD,Kyriacou CP,Reppert SM

更新日期：2001-02-15 00:00:00

abstract：:In the originally published version of this Article, the sequenced axolotl strain (the homozygous white mutant) was denoted as 'D/D' rather than 'd/d' in Fig. 1a and the accompanying legend, the main text and the Methods section. The original Article has been corrected online. ...

journal_title：Nature

authors： Nowoshilow S,Schloissnig S,Fei JF,Dahl A,Pang AWC,Pippel M,Winkler S,Hastie AR,Young G,Roscito JG,Falcon F,Knapp D,Powell S,Cruz A,Cao H,Habermann B,Hiller M,Tanaka EM,Myers EW

更新日期：2018-07-01 00:00:00

abstract：:Opsin, the ligand-free form of the G-protein-coupled receptor rhodopsin, at low pH adopts a conformationally distinct, active G-protein-binding state known as Ops*. A synthetic peptide derived from the main binding site of the heterotrimeric G protein-the carboxy terminus of the alpha-subunit (GalphaCT)-stabilizes Ops...

journal_title：Nature

authors： Scheerer P,Park JH,Hildebrand PW,Kim YJ,Krauss N,Choe HW,Hofmann KP,Ernst OP

更新日期：2008-09-25 00:00:00

abstract：:Bone has recently emerged as a pleiotropic endocrine organ that secretes at least two hormones, FGF23 and osteocalcin, which regulate kidney function and glucose homeostasis, respectively. These findings have raised the question of whether other bone-derived hormones exist and what their potential functions are. Here ...

journal_title：Nature

authors： Mosialou I,Shikhel S,Liu JM,Maurizi A,Luo N,He Z,Huang Y,Zong H,Friedman RA,Barasch J,Lanzano P,Deng L,Leibel RL,Rubin M,Nickolas T,Chung W,Zeltser LM,Williams KW,Pessin JE,Kousteni S

更新日期：2017-03-16 00:00:00

abstract：:Barophilic bacteria inhabit the deep oceans, and the specific functional modifications and regulatory mechanisms which govern adaptation to hydrostatic pressure are beginning to be understood. For example, the rate of production of several proteins by some hydrothermal vent archaebacteria and the degree of saturation ...

journal_title：Nature

authors： Bartlett D,Wright M,Yayanos AA,Silverman M

更新日期：1989-11-30 00:00:00

abstract：:The crystal structure of the diphtheria toxin dimer at 2.5 A resolution reveals a Y-shaped molecule of three domains. The catalytic domain, called fragment A, is of the alpha + beta type. Fragment B actually consists of two domains. The transmembrane domain consists of nine alpha-helices, two pairs of which are unusua...

journal_title：Nature

authors： Choe S,Bennett MJ,Fujii G,Curmi PM,Kantardjieff KA,Collier RJ,Eisenberg D

更新日期：1992-05-21 00:00:00

abstract：:Contamination of ground waters with water-soluble aromatic hydrocarbons, common components of petroleum pollution, often produces anoxic conditions under which microbial degradation of the aromatics is slow. Oxygen is often added to contaminated ground water to stimulate biodegradation, but this can be technically dif...

journal_title：Nature

authors： Lovley DR,Woodward JC,Chapelle FH

更新日期：1994-07-14 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Nature

authors： Ainsworth C

更新日期：2017-11-08 00:00:00

abstract：:With the current shortage in fetal bovine serum, researchers are turning to a variety of options for cell and tissue culture. ...

journal_title：Nature

authors： Jayme DW,Epstein DA,Conrad DR

更新日期：1988-08-11 00:00:00

abstract：: ...

journal_title：Nature

authors： Cyranoski D

更新日期：2019-02-01 00:00:00

abstract：:Sex differences in behaviour extend to cognitive-like processes such as learning, but the underlying dimorphisms in neural circuit development and organization that generate these behavioural differences are largely unknown. Here we define at the single-cell level-from development, through neural circuit connectivity,...

journal_title：Nature

authors： Sammut M,Cook SJ,Nguyen KCQ,Felton T,Hall DH,Emmons SW,Poole RJ,Barrios A

更新日期：2015-10-15 00:00:00

abstract：:Phase and antigenic variation of pilin expression in Neisseria gonorrhoeae result from recombination events in which variant sequences from one of the silent loci (pilS) are transferred to the expression locus (pilE). Such rearrangements were originally thought to be gene conversions, but findings showing that phase v...

journal_title：Nature

authors： Gibbs CP,Reimann BY,Schultz E,Kaufmann A,Haas R,Meyer TF

更新日期：1989-04-20 00:00:00

abstract：:Mycobacterium tuberculosis (Mtb) is the leading cause of death from infection worldwide1. The only available vaccine, BCG (Bacillus Calmette-Guérin), is given intradermally and has variable efficacy against pulmonary tuberculosis, the major cause of mortality and disease transmission1,2. Here we show that intravenous ...

journal_title：Nature

authors： Darrah PA,Zeppa JJ,Maiello P,Hackney JA,Wadsworth MH 2nd,Hughes TK,Pokkali S,Swanson PA 2nd,Grant NL,Rodgers MA,Kamath M,Causgrove CM,Laddy DJ,Bonavia A,Casimiro D,Lin PL,Klein E,White AG,Scanga CA,Shalek AK,Roede

更新日期：2020-01-01 00:00:00

abstract：:Vaccines rarely provide full protection from disease. Nevertheless, partially effective (imperfect) vaccines may be used to protect both individuals and whole populations. We studied the potential impact of different types of imperfect vaccines on the evolution of pathogen virulence (induced host mortality) and the co...

journal_title：Nature

authors： Gandon S,Mackinnon MJ,Nee S,Read AF

更新日期：2001-12-13 00:00:00

abstract：:During the evolution of sea urchins, a transfer RNA gene lost its tRNA function and became part of a protein-coding gene. This functional loss of a tRNA with specificity for one group of leucine codons (CUN, where N is any base) was accompanied by the gain of a new tRNA with that specificity. The new tRNA gene for CUN...

journal_title：Nature

authors： Cantatore P,Gadaleta MN,Roberti M,Saccone C,Wilson AC

更新日期：1987-10-29 00:00:00

abstract：:Plasmacytoid dendritic cells (pDCs) sense viral and microbial DNA through endosomal Toll-like receptors to produce type 1 interferons. pDCs do not normally respond to self-DNA, but this restriction seems to break down in human autoimmune disease by an as yet poorly understood mechanism. Here we identify the antimicrob...

journal_title：Nature

authors： Lande R,Gregorio J,Facchinetti V,Chatterjee B,Wang YH,Homey B,Cao W,Wang YH,Su B,Nestle FO,Zal T,Mellman I,Schröder JM,Liu YJ,Gilliet M

更新日期：2007-10-04 00:00:00

abstract：:N-glycosylation of proteins in the endoplasmic reticulum (ER) has a central role in protein quality control. Here we report that N-glycan serves as a signal for degradation by the Skp1-Cullin1-Fbx2-Roc1 (SCF(Fbx2)) ubiquitin ligase complex. The F-box protein Fbx2 (ref. 4) binds specifically to proteins attached to N-l...

journal_title：Nature

authors： Yoshida Y,Chiba T,Tokunaga F,Kawasaki H,Iwai K,Suzuki T,Ito Y,Matsuoka K,Yoshida M,Tanaka K,Tai T

更新日期：2002-07-25 00:00:00

abstract：:When a force deforms an elastic object, practical experience suggests that the resulting displacement will be in the same direction as the force. This property is known as positive stiffness. Less familiar is the concept of negative stiffness, where the deforming force and the resulting displacement are in opposite di...

journal_title：Nature

authors： Lakes RS,Lee T,Bersie A,Wang YC

更新日期：2001-03-29 00:00:00

abstract：:In animals, maternal gene products deposited into eggs regulate embryonic development before activation of the zygotic genome. In plants, an analogous period of prolonged maternal control over embryogenesis is thought to occur based on some gene-expression studies. However, other gene-expression studies and genetic an...

journal_title：Nature

authors： Nodine MD,Bartel DP

更新日期：2012-01-22 00:00:00

abstract：:Multiple sulphatase deficiency disease is an unusual autosomal recessive disorder characterised biochemically by a deficiency of several sulphohydrolase activities. The laboratory diagnosis of this combined neurological connective tissue disorder is made on the basis of decreased activities of the lysosomal enzymes, a...

journal_title：Nature

authors： Fiddler MB,Vine D,Shapira E,Nadler HL

更新日期：1979-11-01 00:00:00