Hepatic artery embolization for metastatic endocrine-secreting tumors of the pancreas. Report of two cases.

abstract：BACKGROUND & AIMS:Crohn's disease (CD) is an immunologically mediated inflammatory disease of the gastrointestinal tract. Due to a high morbidity and/or an increase in mortality in refractory cases, a new treatment approach is needed. In theory, maximum immune ablation by autologous hematopoietic stem cell transplantat...

journal_title：Gastroenterology

authors： Oyama Y,Craig RM,Traynor AE,Quigley K,Statkute L,Halverson A,Brush M,Verda L,Kowalska B,Krosnjar N,Kletzel M,Whitington PF,Burt RK

更新日期：2005-03-01 00:00:00

abstract：:The effect of secretin5-27 and four substituted analogues (9 Gln-secretin5-27, 15-Asn-secretin5-27, 9-Gln-15-Asn-secretin5-27, and 15-Lys-secretin5-27) on pancreatic secretion in the rat and guinea pig was examined. Secretin5-27 retained significant pancreatic secretory activity in both species. Its efficacy (intrinsi...

journal_title：Gastroenterology

authors： Makhlouf GM,Bodanszky M,Fink ML,Schebalin M

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND & AIMS:Helicobacter pylori is an important etiologic factor in the development of gastric cancer. The aim of this study was to analyze the role of H. pylori infections in the induction of mutagenic events in gastric epithelial cells. The effect of a high-salt diet as a genotoxic risk factor was also investig...

journal_title：Gastroenterology

authors： Touati E,Michel V,Thiberge JM,Wuscher N,Huerre M,Labigne A

更新日期：2003-05-01 00:00:00

abstract：:The assimilation of labeled cobalamin and the transport of corrinoids in portal blood, peripheral venous blood, and bile were studied in eight cholecystectomized patients, after ingestion of a dose of cyano[57Co]cobalamin (0.5 microCi). The radioactivity appeared in the portal vein after a delay of 1.5-2 hours and in ...

journal_title：Gastroenterology

authors： el Kholty S,Gueant JL,Bressler L,Djalali M,Boissel P,Gerard P,Nicolas JP

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND & AIMS:Ethanol impairs the mitochondrial transport of reduced glutathione (GSH), resulting in lower mitochondrial GSH (mGSH) levels. Our purpose was to evaluate the role of acetaldehyde on the regulation of mGSH in HepG2 cells. METHODS:mGSH levels and transport, mitochondrial membrane microviscosity, and li...

journal_title：Gastroenterology

authors： Lluis JM,Colell A,García-Ruiz C,Kaplowitz N,Fernández-Checa JC

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND/AIMS:Recent in vivo studies using proton magnetic resonance (1H-MR) spectroscopy showed low levels of myo-inositol in the brain in hepatic encephalopathy; the pathogenetic relevance of this observation is unclear. METHODS:Myo-inositol and glutamine levels in the brain were studied in vivo by 1H-MR spectrosc...

journal_title：Gastroenterology

authors： Häussinger D,Laubenberger J,vom Dahl S,Ernst T,Bayer S,Langer M,Gerok W,Hennig J

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND & AIMS:Mucosal cell-mediated immune response is considered the central event in the pathogenesis of celiac disease. In cultured intestinal explants from celiacs in remission, we have characterized the early stages of gliadin-induced immune activation. METHODS:Intestinal biopsy specimens (15 treated celiacs ...

journal_title：Gastroenterology

authors： Maiuri L,Picarelli A,Boirivant M,Coletta S,Mazzilli MC,De Vincenzi M,Londei M,Auricchio S

更新日期：1996-05-01 00:00:00

abstract：:To determine the long-term efficacy, safety, and toxicity of omeprazole, we studied 40 patients with Zollinger-Ellison syndrome given omeprazole for 6-51 mo (median 29). The mean daily dose of omeprazole required to control gastric acid secretion was 82 +/- 31 mg. Thirty-one patients required omeprazole once per day. ...

journal_title：Gastroenterology

authors： Maton PN,Vinayek R,Frucht H,McArthur KA,Miller LS,Saeed ZA,Gardner JD,Jensen RT

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND & AIMS:Crohn's disease has a bimodal age distribution of disease onset diagnosis. The peaks (20 and 50 years) may represent different phenotypes or different genetic and/or environmental influences between younger- and older-onset individuals. The aim of this study was to examine the influences of age at dia...

journal_title：Gastroenterology

authors： Polito JM 2nd,Childs B,Mellits ED,Tokayer AZ,Harris ML,Bayless TM

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND & AIMS:Epithelial stem cells in the stomach are responsible for constant renewal of the epithelium through generation of multiple gastric cell lineages that populate the gastric glands. However, gastric stem or progenitor cells have not been well-characterized because of the lack of specific markers that per...

journal_title：Gastroenterology

authors： Qiao XT,Ziel JW,McKimpson W,Madison BB,Todisco A,Merchant JL,Samuelson LC,Gumucio DL

更新日期：2007-12-01 00:00:00

abstract：:Mucins synthesized in colonic cancer are known to be different from those in the normal colon; however, the biochemical differences between these mucins have not been defined. We have purified mucins from samples of nonneoplastic (normal) human colon and colon cancer and found that the carbohydrate content of the canc...

journal_title：Gastroenterology

authors： Boland CR,Deshmukh GD

更新日期：1990-05-01 00:00:00

abstract：:An animal model for giardiasis was developed using Giardia muris in Swiss albino mice. Intraesophageal inoculation of G. muris cysts caused a reproducible pattern of infection, with trophozoite and cyst counts reaching a maximum on days 5 to 14 after cyst inoculation and thereafter showing a progressive decline. Spont...

journal_title：Gastroenterology

authors： Roberts-Thomson IC,Stevens DP,Mahmoud AA,Warren KS

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND & AIMS:Amidated gastrins are acid secretagogues and growth factors. Their precursor, progastrin, is a growth factor but not a secretagogue. Cleavage of progastrin at Arg94/95 determines the expression of these two alternative patterns of biological activity. We examined the hypothesis that cleavage at Arg94/...

journal_title：Gastroenterology

authors： Bishop L,Dimaline R,Blackmore C,Deavall D,Dockray GJ,Varro A

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND & AIMS:The enteric nervous system (ENS) coordinates essential intestinal functions through the concerted action of diverse enteric neurons (ENs). However, integrated molecular knowledge of EN subtypes is lacking. To compare human and mouse ENs, we transcriptionally profiled healthy ENS from adult humans and ...

journal_title：Gastroenterology

authors： May-Zhang AA,Tycksen E,Southard-Smith AN,Deal KK,Benthal JT,Buehler DP,Adam M,Simmons AJ,Monaghan JR,Matlock BK,Flaherty DK,Potter SS,Lau KS,Southard-Smith EM

更新日期：2020-09-30 00:00:00

abstract：:We studied the procoagulant activity of peripheral blood monocytes in 41 patients with severe obstructive jaundice and in 27 nonjaundiced control patients using a one-stage clotting assay. Mononuclear cells from jaundiced patients, tested immediately after isolation, expressed low levels of procoagulant activity, whic...

journal_title：Gastroenterology

authors： Semeraro N,Montemurro P,Chetta G,Altomare DF,Giordano D,Colucci M

更新日期：1989-03-01 00:00:00

abstract：:An enteroscopic method that uses a pediatric colonoscope provides an alternative approach to the diagnostic and management problems arising in the setting of a Roux-en-Y limb hepaticojejunostomy or biliary diversion. Three patients with Roux-en-Y limb reconstructions who experienced recurrent cholangitis, recurrent pa...

journal_title：Gastroenterology

authors： Gostout CJ,Bender CE

更新日期：1988-07-01 00:00:00

abstract：:A strict gluten-free diet (GFD) for life is the only treatment for celiac disease (CD). This article reviews (1) the impact of the GFD on the quality of life of individuals with CD and their families; (2) the causes of poorly controlled CD; (3) the access to and source and quality of information provided by health pro...

journal_title：Gastroenterology

authors： Case S

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND/AIMS:During liver fibrosis, there is a putative pacemaker role of fibronectin. Fibrinogen is closely linked to fibronectin during clotting processes. The aim of this study was to show fibrinogen gene expression during liver damage. METHODS:Fibrinogen/fibrin deposition in damaged livers was studied by immuno...

journal_title：Gastroenterology

authors： Neubauer K,Knittel T,Armbrust T,Ramadori G

更新日期：1995-04-01 00:00:00

abstract：:Disseminated cytomegalovirus infection occurs predominantly in immunocompromised hosts. Involvement of the gastrointestinal tract in the acquired immunodeficiency syndrome is frequent, but to our knowledge there is only one report of involvement of the appendix. In this study, a patient with a history of the acquired ...

journal_title：Gastroenterology

authors： Valerdiz-Casasola S,Pardo-Mindan FJ

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND & AIMS:Intrapancreatic activation of digestive enzymes is a key event in the parenchymal cell injury of pancreatitis. We hypothesized that neutrophils recruited to the pancreas during pancreatitis may contribute to such activation. METHODS:To cause experimental pancreatitis, rats and mice were treated with ...

journal_title：Gastroenterology

authors： Gukovskaya AS,Vaquero E,Zaninovic V,Gorelick FS,Lusis AJ,Brennan ML,Holland S,Pandol SJ

更新日期：2002-04-01 00:00:00

abstract：:The aim of this study was to assess the effect of cell culture on the bradykinin receptor of rabbit colon myocytes. In longitudinal muscle strips prepared from distal colon, bradykinin stimulated dose-dependent contraction that was 62% of the maximal response to bethanecol. At 4 degrees C, [3H]bradykinin binding to fr...

journal_title：Gastroenterology

authors： Hyman PE,Diego A,Ridout D,Yuan QX,Ennes H,Cominelli F,Snape WJ Jr,Tomomasa T

更新日期：1992-05-01 00:00:00

abstract：:Extracellular space and blood volume were measured using 82Br dilution and 51Cr-tagged erythrocytes in 24 tumor-free patients after total gastrectomy. Eleven of the patients suffered from early dumping. Age, blood volume, and extracellular space were significantly smaller in dumpers (P less than 0.05). The dumping sco...

journal_title：Gastroenterology

authors： Miholic J,Reilmann L,Meyer HJ,Körber H,Kotzerke J,Hecker H

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND & AIMS:We previously isolated a monoclonal antibody against a Necturus gallbladder epitope that blocks native adenosine 3',5'-cyclic monophosphate (cAMP)-dependent chloride channels in intestine, gallbladder, urinary bladder, and airway epithelia in various animals. METHODS:Using this antibody, we purified ...

journal_title：Gastroenterology

authors： Finn AL,Kuzhikandathil EV,Oxford GS,Itoh-Lindstrom Y

更新日期：2001-01-01 00:00:00

abstract：:We describe a novel "silvering" method to determine the surface area of nonspherical objects and have applied this method to human cholesterol gallstones. A standard curve is first constructed, using data obtained from the dissolution rates of silver-coated plastic spheres of known dimensions in unstirred thiosulfate-...

journal_title：Gastroenterology

authors： Park YH,Igimi H,Carey MC

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND & AIMS:Rabs are monomeric guanosine triphosphatases that regulate membrane trafficking and acid secretion in gastric parietal cells. Using a proteomics approach, we identified a new Rab, Rab27b, in tubulovesicle membranes and determined its role in parietal cell activation. METHODS:We used mass spectrometry...

journal_title：Gastroenterology

authors： Suda J,Zhu L,Okamoto CT,Karvar S

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND & AIMS:Microsatellite instability is a property of most tumors occurring in the context of hereditary nonpolyposis colon cancer. Instability also occurs in 10%-15% of apparently sporadic colorectal cancers, and it has been hypothesized that this instability may indicate a genetic predisposition to colonic ca...

journal_title：Gastroenterology

authors： Samowitz WS,Slattery ML,Kerber RA

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND & AIMS:Tobacco smoking has a complex effect on intestinal inflammation, being protective in ulcerative colitis, whereas it aggravates Crohn's disease. The beneficial effect of smoking has been attributed to nicotine, but the mechanisms underlying the adverse effect are still under investigation. The aim of t...

journal_title：Gastroenterology

authors： Galeazzi F,Blennerhassett PA,Qiu B,O'Byrne PM,Collins SM

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND & AIMS:Some patients with irritable bowel syndrome with diarrhea (IBS-D) have intestinal hyperpermeability, which contributes to their diarrhea and abdominal pain. MicroRNA 29 (MIR29) regulates intestinal permeability in patients with IBS-D. We investigated and searched for targets of MIR29 and investigated ...

journal_title：Gastroenterology

authors： Zhou Q,Costinean S,Croce CM,Brasier AR,Merwat S,Larson SA,Basra S,Verne GN

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND & AIMS:The effects of short-term antigenic activation of mast cells on the gastrointestinal tract have been well characterized, but little is known about the effects of long-term exposure to antigen on mucosal mast cell reactivity. The aim of this study was to determine the effects of long-term antigen expos...

journal_title：Gastroenterology

authors： Rioux KP,Wallace JL

更新日期：1996-12-01 00:00:00

abstract：:If increased gamma-aminobutyric acid (GABA)-mediated neurotransmission contributes to the mediation of hepatic encephalopathy, it may be possible to induce ameliorations of the syndrome by pharmacologically antagonizing a component of the GABA/benzodiazepine receptor complex. To test this possibility we administered t...

journal_title：Gastroenterology

authors： Bansky G,Meier PJ,Riederer E,Walser H,Ziegler WH,Schmid M

更新日期：1989-09-01 00:00:00