Extracellular space, blood volume, and the early dumping syndrome after total gastrectomy.

Abstract:

:Extracellular space and blood volume were measured using 82Br dilution and 51Cr-tagged erythrocytes in 24 tumor-free patients after total gastrectomy. Eleven of the patients suffered from early dumping. Age, blood volume, and extracellular space were significantly smaller in dumpers (P less than 0.05). The dumping score could be predicted by a multiple regression model considering blood volume per lean body mass and extracellular space (r = 0.637; P = 0.0039). Rapid (t1/2 less than 360 seconds) emptying of the gastric substitute, assessed using a 99Tc-labeled solid test meal, was significantly associated with dumping in addition to extracellular space and blood volume (r = 0.876; P = 0.0018). Both rapid emptying and a narrow extracellular space seem to contribute to the early dumping syndrome.

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Miholic J,Reilmann L,Meyer HJ,Körber H,Kotzerke J,Hecker H

doi

10.1016/0016-5085(90)90608-4

subject

Has Abstract

pub_date

1990-10-01 00:00:00

pages

923-9

issue

4

eissn

0016-5085

issn

1528-0012

pii

0016-5085(90)90608-4

journal_volume

99

pub_type

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