Comparison between pore model predictions and sheep lung fluid and protein transport.

abstract：:Patients with diabetic polyneuropathy are known to have an impaired neurovascular reflex arc compared to healthy controls. This is seen in a delayed decrease in microcirculation of the ipsilateral hand after cooling of the contralateral hand. The aim of this pilot study was to investigate whether intravenous alpha-lip...

journal_title：Microvascular research

authors： Haak ES,Usadel KH,Kohleisen M,Yilmaz A,Kusterer K,Haak T

更新日期：1999-07-01 00:00:00

abstract：:Metabolic syndrome (MetS) is a combination of clinical disorders that together increase the risk for cardiovascular disease and diabetes. SHRSP.Z-Lepr(fa)/IzmDmcr (SHRSP.ZF) rats with MetS show impaired nitric oxide-mediated relaxation in coronary and mesenteric arteries, and angiotensin II receptor type 1 blockers pr...

journal_title：Microvascular research

authors： Kagota S,Maruyama K,Tada Y,Fukushima K,Umetani K,Wakuda H,Shinozuka K

更新日期：2013-07-01 00:00:00

abstract：:Studies of microvascular geometry made from microscope observations of tissues in vivo or after perfusion with a silastic elastomer or india ink are restricted to a two-dimensional field of view. Microvascular corrosion casts, however, if of sufficient rigidity and structural integrity, can yield three-dimensional inf...

journal_title：Microvascular research

authors： Potter RF,Groom AC

更新日期：1983-01-01 00:00:00

abstract：:The contribution of the pleural mesothelium to pleural liquid and protein transport is still vigorously debated. Recent in vitro studies of stripped pleural membrane and free-standing pericardium have demonstrated active ion solute coupled transport of liquid and transcytosis of protein. However, the relative contribu...

journal_title：Microvascular research

authors： Tang SM,Lai-Fook SJ

更新日期：2005-11-01 00:00:00

abstract：:A large loss of blood during hemorrhage can result in profound shock, a state of hypotension associated with hemodynamic abnormalities. One of the hypotheses to account for this collapse of homeostasis is that the production of nitric oxide (NO), a gas molecule that dilates blood vessels, is significantly impaired dur...

journal_title：Microvascular research

authors： Chen K,Pittman RN,Popel AS

更新日期：2009-06-01 00:00:00

abstract：:We present a simple method for isolation and long-term cultivation of porcine and murine cerebral capillary endothelial cells (cEC). Two major points are made. First, that the "characteristic" morphology of the endothelial cells depends mainly on the presence of endothelial cell growth factors in the culture medium an...

journal_title：Microvascular research

authors： Tontsch U,Bauer HC

更新日期：1989-03-01 00:00:00

abstract：:Endometriosis, the presence of endometrium-like tissue outside of the uterine cavity, is a common disease among women of reproductive age. Typical symptoms include abdominal pain and painful menstruation. In addition, endometriosis is associated with reduced fertility. Current treatment modalities, the surgical remova...

journal_title：Microvascular research

authors： Becker CM,D'Amato RJ

更新日期：2007-09-01 00:00:00

abstract：:Pericytes are perivascular support cells, the origin of which in tumor tissue is not clear. Recently, we identified a Tie1(+) precursor cell that differentiates into vascular smooth muscle, in a Notch-dependent manner. To understand the involvement of Notch in the ontogeny of tumor pericytes we used a novel flow immun...

journal_title：Microvascular research

authors： Patenaude A,Woerher S,Umlandt P,Wong F,Ibrahim R,Kyle A,Unger S,Fuller M,Parker J,Minchinton A,Eaves CJ,Karsan A

更新日期：2015-09-01 00:00:00

abstract：:We investigated the expression of cell adhesion molecules on the surface of glomerular endothelial cells (GEC), dermal microvascular endothelial cells (MvE), and umbilical vein endothelial cells (HUVEC) that had or had not been stimulated by cytokines. PECAM-1 was constitutively expressed at a high level on HUVEC but ...

journal_title：Microvascular research

authors： Murakami S,Morioka T,Nakagawa Y,Suzuki Y,Arakawa M,Oite T

更新日期：2001-11-01 00:00:00

abstract：:Particle adhesion in vivo is highly dependent on the microvascular environment comprising of unique anatomical, geometrical, physiological fluid flow conditions and cell-particle and cell-cell interactions. Hence, proper design of vascular-targeted drug carriers that efficiently deliver therapeutics to the targeted ce...

journal_title：Microvascular research

authors： Lamberti G,Soroush F,Smith A,Kiani MF,Prabhakarpandian B,Pant K

更新日期：2015-05-01 00:00:00

abstract：:We studied the absorbing peripheral lymphatic vessel with the light microscope, the transmission electron microscope, the scanning electron microscope, and three-dimensional models of the diaphragm of several rodents and insectivores under normal and experimental conditions (lymphatic stasis and dehydration). To clari...

journal_title：Microvascular research

authors： Azzali G

更新日期：1999-01-01 00:00:00

abstract：:Red blood cell (RBC)-plasma suspensions with a hematocrit of 10-12% were forced to flow through microchannels (equivalent diameter 6 microns, equivalent length 20 microns, 2600 in parallel) by applying a pressure difference of 20 cm H2O. Transit times for 100 microliters of fresh suspensions from 33 healthy male subje...

journal_title：Microvascular research

authors： Kikuchi Y,Da QW,Fujino T

更新日期：1994-03-01 00:00:00

abstract：:Endothelial cells and endothelial progenitor cells (EPCs) play a key role in the pathogenesis of vascular disease. Both cell types are affected by the oxidative stress but their susceptibility may be different. This study aimed to investigate the antioxidative enzymes activated in EPCs after high constant glucose expo...

journal_title：Microvascular research

authors： Felice F,Lucchesi D,di Stefano R,Barsotti MC,Storti E,Penno G,Balbarini A,Del Prato S,Pucci L

更新日期：2010-12-01 00:00:00

abstract：:Lipopolysaccharide released during bacterial sepsis causes acute lung injury and ARDS. Pulmonary microvascular injury is a feature of ARDS, and vascular remodeling develops, leading to pulmonary hypertension. Pericytes in the lung circulation proliferate and contribute to the remodeling seen in experimental sepsis. It...

journal_title：Microvascular research

authors： Khoury J,Langleben D

更新日期：1998-09-01 00:00:00

abstract：:The purpose of this study was to investigate reactive hyperemia in the capillary network of human skin in terms of the flow per capillary and the density of flow-active capillaries. Seventeen male subjects 20 to 40 years of age were seated with their right foot placed on the stage of a Leitz epi-ilumination microscope...

journal_title：Microvascular research

authors： Richardson D,Schwartz R,Hyde G

更新日期：1985-07-01 00:00:00

abstract：:Placental development requires coordinated angiogenesis regulated by multiple factors including angiopoietins. Previously we demonstrated that the concentration of angiopoietin-2 (Ang-2) in the sera of women rises markedly in pregnancy in early gestation. This increase is reduced in pregnancies subsequently complicate...

journal_title：Microvascular research

authors： Woolnough C,Wang Y,Kan CY,Morris JM,Tasevski V,Ashton AW

更新日期：2012-11-01 00:00:00

abstract：:Oxygen pressure histograms were determined with the multiwire surface electrode from the gastrocnemius muscle in patients with arterial occlusive disease and compared with those of healthy volunteers. Seven out of 22 patients had normally distributed histograms like volunteers, but the mean PO2 values were lower than ...

journal_title：Microvascular research

authors： Creutzig A,Wrabetz W,Lux M,Alexander K

更新日期：1985-05-01 00:00:00

abstract：:Particle tracking velocimetry provides a Lagrangian description of flow properties in the microcirculation. To determine the utility of fluorescent nanoparticles to provide Lagrangian coordinates, we tracked these particles both in vitro and in vivo. The particles had a neutral charge and fluorescence intensity greate...

journal_title：Microvascular research

authors： Ravnic DJ,Zhang YZ,Tsuda A,Pratt JP,Huss HT,Mentzer SJ

更新日期：2006-07-01 00:00:00

abstract：:Skeletal muscle arterioles are known to constrict upon elevation of ambient PO2. While several studies have shown that the endothelium plays an important role in this response, it is not clear how this response is mediated. We examined the oxygen-induced constriction of arterioles in the rat spinotrapezius muscle. Ele...

journal_title：Microvascular research

authors： Pries AR,Heide J,Ley K,Klotz KF,Gaehtgens P

更新日期：1995-05-01 00:00:00

abstract：:Although vasodilation is conventionally held to be the predominant microvascular response to a wound, there has been no previous attempt to actually quantitate skin blood flow within and in the neighborhood of wounds. In particular, there has been no differentiation between sites with primarily nutritive (NUTR) blood ...

journal_title：Microvascular research

authors： Rendell MS,Milliken BK,Finnegan MF,Finney DA,Healy JC

更新日期：1997-05-01 00:00:00

abstract：:In diabetic patients small fiber neuropathy has been associated with impairment of 0.1 Hz microvascular vasomotion. The aim of this study was (1) to investigate whether vasoconstriction-induced microvascular oscillations in the skin are reduced in diabetic patients with peripheral and/or autonomic neuropathy, and (2) ...

journal_title：Microvascular research

authors： Schmiedel O,Nurmikko TJ,Schroeter ML,Whitaker R,Harvey JN

更新日期：2008-08-01 00:00:00

abstract：:Fluorescence-mediated photoplethysmography (FM-PPG) was developed to facilitate determination of tissue microvascular (capillary) blood perfusion, requiring intra-venous injection of a small bolus (~0.33mL) of dye (25mg/mL ICG) and acquisition of high-speed angiogram images (>15images/s). The methodology is applicable...

journal_title：Microvascular research

authors： Flower RW,Kling R

更新日期：2017-11-01 00:00:00

abstract：:The microfibrils of anchoring filaments, a typical ultrastructural feature of initial lymphatic vessels, consist mainly of fibrillin and are similar to the microfibrils of elastic fibers. As we previously demonstrated, they radiate from focal adhesions of lymphatic endothelium to the perivascular elastic network. Alth...

journal_title：Microvascular research

authors： Weber E,Rossi A,Solito R,Sacchi G,Agliano' M,Gerli R

更新日期：2002-07-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is a common cause of blindness worldwide. While recent studies have revealed that the loss of choroidal endothelial cells (ChECs) is critical to the disease pathogenesis of dry AMD, in vitro studies are needed to fully elucidate the disease mechanism. However, these studies remai...

journal_title：Microvascular research

authors： Giacalone JC,Miller MJ,Workalemahu G,Reutzel AJ,Ochoa D,Whitmore SS,Stone EM,Tucker BA,Mullins RF

更新日期：2019-05-01 00:00:00

abstract：:We describe a sensitive, reliable, and convenient procedure to assay cell adhesion based on flow cytometry which allows quantitative studies of all major peripheral blood leukocytes adhering to microvascular endothelial cells. Using this assay, we show that adhesion of mononuclear cells is significantly increased in t...

journal_title：Microvascular research

authors： Heckmann M,Pirthauer M

更新日期：1996-09-01 00:00:00

abstract：:Blood flow studies in the brain, heart, and other organs suggest that there could be interaction between nitric oxide (NO) and adenosine. This possibility was investigated in the optic nerve head (ONH) during photic stimulation of the dark-adapted cat eye. Functional activation of ONH blood flow was measured by laser ...

journal_title：Microvascular research

authors： Buerk DG,Riva CE

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:To examine the possible role of Klotho (Kl) in human microvasculature. METHODS:The expression level of Kl in primary human dermal microvascular endothelial cells (HDMECs) and primary human dermal fibroblasts (HFb) was detected by real-time polymerase chain reaction amplification (qRT-PCR), Western blot analyse...

journal_title：Microvascular research

authors： Markiewicz M,Panneerselvam K,Marks N

更新日期：2016-09-01 00:00:00

abstract：:We evaluated the effect of an oral glucose tolerance test (OGTT) on the level of biomarkers of vascular remodelling. We enrolled 256 Caucasian overweight healthy subjects (H) and 274 overweight type 2 diabetic patients (D). All patients underwent basal measurements of blood glucose (BG), nitrites/nitrates, adiponectin...

journal_title：Microvascular research

authors： Derosa G,D'Angelo A,Salvadeo SA,Ferrari I,Fogari E,Gravina A,Mereu R,Palumbo I,Maffioli P,Randazzo S,Cicero AF

更新日期：2010-03-01 00:00:00

abstract：:We have developed a simplified technique for culturing human umbilical vein endothelial cells under shear flow conditions, using prefabricated glass microcapillary tubes ("microslides") with a well-defined rectangular cross section and good optical quality. These microslides have been incorporated into a controlled fl...

journal_title：Microvascular research

authors： Cooke BM,Usami S,Perry I,Nash GB

更新日期：1993-01-01 00:00:00

abstract：:The microcirculation in normal and arthritic juxtaarticular bone was studied in 16 young dogs with carragheenan-induced arthritis of one knee. The regional blood flow was determined by the tissue uptake of intracardially injected 15-microns 141Ce-labeled microspheres, and the microvascular plasma volume was determined...

journal_title：Microvascular research

authors： Hansen ES,Søballe K,Kjølseth D,Henriksen TB,He SZ

更新日期：1990-09-01 00:00:00