Distribution of the human jaw stretch reflex response elicited by percutaneous, localized stretch of jaw-closing muscles.

abstract：:Autonomic dysreflexia is a condition of episodic hypertension that develops after spinal cord injury (SCI). We previously showed that a two-day anti-inflammatory treatment with an anti-CD11d integrin monoclonal antibody (mAb), soon after SCI in rats, reduced the magnitude of dysreflexia for at least 6 weeks. Effects o...

journal_title：Experimental neurology

authors： Gris D,Marsh DR,Dekaban GA,Weaver LC

更新日期：2005-08-01 00:00:00

abstract：:Overt behavioral symptoms of Parkinson's disease (PD) do not occur until over 80% of the striatal dopamine content has been lost. Diagnosis of the disorder relies on identifying clinical symptoms including akinesia, resting tremor, and rigidity. In retrospect, behavioral deficits are observed several years prior to di...

journal_title：Experimental neurology

authors： Tillerson JL,Caudle WM,Reverón ME,Miller GW

更新日期：2002-11-01 00:00:00

abstract：:Discovery of new central nervous system (CNS) acting therapeutics has been slowed down by the lack of useful applicable biomarkers of disease or drug action often due to inaccessibility of relevant human CNS tissue and cell types. In recent years, non-neuronal cells, such as astrocytes, have been reported to play a hi...

journal_title：Experimental neurology

authors： Sattler R,Ayukawa Y,Coddington L,Sawa A,Block D,Chipkin R,Rothstein JD

更新日期：2011-12-01 00:00:00

abstract：:Alpha-synuclein (alphaSN) is implicated in Parkinson's disease (PD) and is the major component of Lewy bodies (LBs). Although alphaSN is mainly expressed in neuronal cells and exists as a cytoplasmic protein, it has been found in body fluids including cerebrospinal fluid and blood. This study explored plasma alphaSN a...

journal_title：Experimental neurology

authors： Li QX,Mok SS,Laughton KM,McLean CA,Cappai R,Masters CL,Culvenor JG,Horne MK

更新日期：2007-04-01 00:00:00

abstract：:Peripheral nerve crush injury (PNCI) has been used for many years in adult animals to study central and peripheral changes related to regeneration across the injury site. While these adult animals experience full recovery with no neuronal cell loss following PNCI, it has been noted that the injury in perinatal animals...

journal_title：Experimental neurology

authors： Kuzis K,Coffin JD,Eckenstein FP

更新日期：1999-05-01 00:00:00

abstract：:Russian knapweed is a perennial weed found in many parts of the world, including southern California. Chronic ingestion of this plant by horses has been reported to cause equine nigropallidal encephalomalacia (ENE), which is associated with a movement disorder simulating Parkinson's disease (PD). Repin, a principal in...

journal_title：Experimental neurology

authors： Robles M,Choi BH,Han B,Santa Cruz K,Kim RC

更新日期：1998-07-01 00:00:00

abstract：:Neurons lesioned in the peripheral nervous system (PNS) generally regenerate and survive, while neurons lesioned in the central nervous system (CNS) do not regenerate and often die. Investigators have traditionally compared the neuronal responses to PNS and CNS lesions in two separate populations of neurons. In this s...

journal_title：Experimental neurology

authors： Book AA,Fischer I,Yu XJ,Iannuzzelli P,Murphy EH

更新日期：1996-04-01 00:00:00

abstract：:The vibrissae of rats were shaved from one side of the face daily for 10 days. To see whether or not this treatment had an effect on crossed and uncrossed striatal afferent connections from the midbrain, the tract tracer horseradish peroxidase was applied to the caudate-putamen on day 11. When the tracer was deposited...

journal_title：Experimental neurology

authors： Huston JP,Morgan S,Lange KW,Steiner H

更新日期：1986-08-01 00:00:00

abstract：:The members of the tenascin family are involved in a number of developmental processes, mainly by their ability to regulate cell adhesion. We have here studied the distribution of mRNAs for tenascin-X, -C, and -R and the closely related molecule tenascin/J1 in the olfactory system and spinal cord. The olfactory bulb a...

journal_title：Experimental neurology

authors： Deckner M,Lindholm T,Cullheim S,Risling M

更新日期：2000-12-01 00:00:00

abstract：:Apolipoprotein E (apoE) is known to bind to at least five receptors, including the low-density lipoprotein (LDL) receptor-related protein (LRP), very low density LDL receptor (VLDL-R), LDL-R, apoE receptor 2 (apoER2), and megalin/gp330. In this context, the main objective of the present study was to better understand ...

journal_title：Experimental neurology

authors： Veinbergs I,Van Uden E,Mallory M,Alford M,McGiffert C,DeTeresa R,Orlando R,Masliah E

更新日期：2001-07-01 00:00:00

abstract：:We have studied the functional involvement of J1-160 and J1-180 in the interaction between oligodendrocytes and neurons, astrocytes, or L cells in short- and long-term adhesion assays using monoclonal antibodies directed against topographically distinct epitopes on the molecules. Whereas antibodies to mouse liver memb...

journal_title：Experimental neurology

authors： Morganti MC,Taylor J,Pesheva P,Schachner M

更新日期：1990-07-01 00:00:00

abstract：:Axonal lesions to the optic nerve (ON) induce c-Jun expression in retinal ganglion cells (RGCs) of the rat in vivo. Detailed investigations using retrograde tracers, and double labeling studies for c-Jun and regeneration-associated factors, such as the growth-associated protein GAP-43, have suggested that this upregul...

journal_title：Experimental neurology

authors： Isenmann S,Bähr M

更新日期：1997-09-01 00:00:00

abstract：:In birds, a variety of subtotal thoracic spinal cord lesions were made to determine the spinal cord pathways essential for avian hind limb locomotion (bipedal walking). The various surgical disruptions included: section of the dorsal half of the cord, a hemisection, section of the dorsal cord and ventromedial funiculi...

journal_title：Experimental neurology

authors： Sholomenko GN,Steeves JD

更新日期：1987-02-01 00:00:00

abstract：:Forebrain-bisected cats underwent kindling at primary and secondary amygdala sites. The behavioral effect of amygdala kindling was then examined according to the extent of the surgical lesion in the forebrain commissures. Bisection of the corpus callosum with or without lesion of the hippocampal commissure modified bo...

journal_title：Experimental neurology

authors： Fukuda H,Wada JA,Riche D,Naquet R

更新日期：1987-10-01 00:00:00

abstract：:Theoretical and experimental analyses of deep brain stimulation (DBS) in the subthalamic nucleus (STN) show both excitatory and inhibitory effects on the neural elements surrounding the electrode. Given these observations, the mechanism underlying the therapeutic effect of STN DBS on parkinsonian motor signs remains u...

journal_title：Experimental neurology

authors： Hahn PJ,Russo GS,Hashimoto T,Miocinovic S,Xu W,McIntyre CC,Vitek JL

更新日期：2008-05-01 00:00:00

abstract：:Posttraumatic stress disorder (PTSD), chronic psychological stress, and major depressive disorder have been found to be associated with a significant decrease in glial fibrillary acidic protein (GFAP) immunoreactivity in the hippocampus of rodents. Cotinine is an alkaloid that prevents memory impairment, depressive-li...

journal_title：Experimental neurology

authors： Perez-Urrutia N,Mendoza C,Alvarez-Ricartes N,Oliveros-Matus P,Echeverria F,Grizzell JA,Barreto GE,Iarkov A,Echeverria V

更新日期：2017-09-01 00:00:00

abstract：:Exposure to early life stress (ELS), such as childhood abuse and neglect is a well established major risk factor for developing psychiatric and behavioral disorders later in life. Both prenatal and postnatal stressors have been shown to have a long-lasting impact on adult pathological states where the type and timing ...

journal_title：Experimental neurology

authors： Provençal N,Binder EB

更新日期：2015-06-01 00:00:00

abstract：:Dorsal root ganglia (DRG) neuronopathy was induced in rats by chronic treatment (2 mg/kg twice a week for nine injections) with the antineoplastic drug cisplatin. Morphological alterations and changes in peptide [calcitonin gene-related peptide (CGRP), substance P, galanin (Gal), and somatostatin] concentration were s...

journal_title：Experimental neurology

authors： Barajon I,Bersani M,Quartu M,Del Fiacco M,Cavaletti G,Holst JJ,Tredici G

更新日期：1996-03-01 00:00:00

abstract：:Spinal cord injury (SCI) is a tragic event causing irreversible losses of sensory, motor, and autonomic functions, that may also be associated with chronic neuropathic pain. Serotonin (5-HT) neurotransmission in the spinal cord is critical for modulating sensory, motor, and autonomic functions. Following SCI, 5-HT axo...

journal_title：Experimental neurology

authors： Perrin FE,Noristani HN

更新日期：2019-08-01 00:00:00

abstract：:Overactivation of N-methyl-D-aspartate (NMDA) glutamate receptors is closely related to epilepsy and excitotoxicity, and the phosphorylation of these receptors may facilitate glutamate-mediated synaptic transmission. Here we show that in awake rats the microinjection into the hippocampus of okadaic acid, a potent inhi...

journal_title：Experimental neurology

authors： Arias C,Montiel T,Peña F,Ferrera P,Tapia R

更新日期：2002-09-01 00:00:00

abstract：:In vivo studies have shown that high blood concentrations of pituitary-adrenocortical hormones can activate the hippocampal cholinergic terminals. Incubation of hippocampal synaptosomal preparations with methylprednisolone, or with ACTH at concentrations comparable to stress-induced high concentrations in plasma, did ...

journal_title：Experimental neurology

authors： Finkelstein Y,Sternfeld M,Yegana Y,Ben-Menahem N,Flechter S,Hod I

更新日期：1987-10-01 00:00:00

abstract：:The effects of superior cervical ganglion stimulation and the local application of norepinephrine or its antagonist propranolol were studied in 18 pineal cells. In 61% of the pineal cells, stimulation elicited excitation; the same cells also responded by excitation to norepinephrine ejection. When stimulation and nore...

journal_title：Experimental neurology

authors： Reyes-Vazquez C,Dafny N

更新日期：1985-12-01 00:00:00

abstract：:Cannabis abuse may precipitate the onset of schizophrenia and a dysfunction of the endocannabinoid system may be involved in the pathology of schizophrenia. Nevertheless, only few studies have addressed the neurobiological consequences of cannabis abuse for the development and course of schizophrenia. We measured the ...

journal_title：Experimental neurology

authors： Rentzsch J,Penzhorn A,Kernbichler K,Plöckl D,Gómez-Carrillo de Castro A,Gallinat J,Jockers-Scherübl MC

更新日期：2007-05-01 00:00:00

abstract：:The possible pain inhibitory effects of periaqueductal gray (PAG) stimulation were investigated in cats anesthetized with Nembutal and immobilized with Flaxedil. Unitary responses evoked by electrical stimulation of the upper canine dentine and by cutaneous facial noxious and nonnoxious stimuli were recorded extracell...

journal_title：Experimental neurology

authors： Figueiras R,Buño W Jr,García-Austt E,Delgado JM

更新日期：1983-07-01 00:00:00

abstract：:Previous studies have suggested that defective high-affinity glutamate uptake, due mainly to a major loss of the astroglial-specific GLT-1 glutamate transporter, underlies the selective motoneuron degeneration observed in sporadic ALS (24, 28). If a defect in glutamate transport underlies the pathogenesis of sporadic ...

journal_title：Experimental neurology

authors： Medina L,Figueredo-Cardenas G,Rothstein JD,Reiner A

更新日期：1996-12-01 00:00:00

abstract：:The present study was carried out to determine if augmentation of phrenic nerve activity during the crossed phrenic phenomenon temporally coincides with the morphological changes in the phrenic nucleus that we have observed in previous studies. This investigation consisted of two experiments in spinal cord hemisected ...

journal_title：Experimental neurology

authors： O'Hara TE Jr,Goshgarian HG

更新日期：1991-02-01 00:00:00

abstract：:A "neuroplastic" hypothesis proposes that changes in neuronal structural plasticity may underlie the aetiology of depression and the action of antidepressants. The medial prefrontal cortex (mPFC) is affected by this disorder and shows an intense expression of the polysialylated form of the neural cell adhesion molecul...

journal_title：Experimental neurology

authors： Castillo-Gómez E,Gómez-Climent MA,Varea E,Guirado R,Blasco-Ibáñez JM,Crespo C,Martínez-Guijarro FJ,Nácher J

更新日期：2008-11-01 00:00:00

abstract：:Periodic changes in ovarian steroid levels during fertility cycles affect learning both in humans and in rats in parallel with electrophysiological and morphological fluctuations in selective neuronal populations. In particular, during the estrous cycle of the female rat, hippocampal CA1 region undergoes cyclic modifi...

journal_title：Experimental neurology

authors： Crispino M,Stone DJ,Wei M,Anderson CP,Tocco G,Finch CE,Baudry M

更新日期：1999-10-01 00:00:00

abstract：:Muscle disuse-induced changes in the cholinergic system of sciatic nerve, slow-twitch soleus (SOL), and fast-twitch extensor digitorum longus (EDL) muscles were studied in rats. Rats with hind limbs suspended for 2 to 3 weeks showed marked elevation in the activity of choline acetyltransferase in sciatic nerve (38%), ...

journal_title：Experimental neurology

authors： Gupta RC,Misulis KE,Dettbarn WD

更新日期：1985-09-01 00:00:00

abstract：:The effects of delta-9-tetrahydrocannabinol on sensory activity in the thalamic intralaminar nuclei, centralis lateralis and the mesencephalic reticular formation were compared with the effects on cortical association or heterosensory systems in alpha-chloralose-anesthetized cats. The drug depressed the anterior margi...

journal_title：Experimental neurology

authors： Pontzer NJ,Wilkison DM

更新日期：1987-09-01 00:00:00