Abstract:
:The location of the perikarya of LH-RH neurons in the rat hypothalamus and their pathways to the median eminence were studied by immunohistochemistry and radioimmunoassay after placing stereotaxic electrolytic lesions in several parts of the hypothalamus. The principal location of the cell somata was found to be in the ventral part of the medial preoptic area; their pathways were classified into a main baso-lateral pathway and an accessory descending pathway branching off from the former. The main pathway was found to cross in the vicinity of the corresponding neuronal perikarya. The central median eminence and the dorsal and ventral walls of the tubero-infundibular sulcus of the caudal part of the median eminence are innervated mainly by the baso-lateral pathway. On the other hand, the rostral and most caudal protions of the median eminence are innervated principally by the descending pathway and have a subsidiary dual innervation. The projection of LH-RH neurons to the OVLT is believed to originate from perikarya adjacent to this circumventricular organ.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Ibata Y,Watanabe K,Kinoshita H,Kubo S,Sano Y,Sin S,Hashimura E,Imagawa Kdoi
10.1007/BF00234184subject
Has Abstractpub_date
1979-05-25 00:00:00pages
381-95issue
3eissn
0302-766Xissn
1432-0878journal_volume
198pub_type
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