Abstract：
:The aim of this study was to determine the efficacy of transcutaneous electrical nerve stimulation (TENS) in the treatment of chronic stable severe angina pectoris. In a short-term study the effect of TENS was studied in 10 male patients with angina pectoris (functional class III and IV). All patients had previously been stabilized on long-term maximal oral treatment. The effects of the treatment were measured by means of repeated bicycle ergometer tests. All patients had an increased working capacity (16-85%), decreased ST segment depression and reduced recovery time during TENS. No adverse effects were observed. A long-term study of TENS on similarly selected patients showed beneficial effects in terms of pain reduction, reduced frequency of anginal attacks, increased physical activity and increased working capacity during bicycle ergometer tests. An invasive study was carried out with respect to systemic and coronary hemodynamics and myocardial metabolism during pacing provoked myocardial ischemia in 13 patients. The results showed that TENS led to an increased tolerance to pacing, improved lactate metabolism, less pronounced ST segment depression. A drop in systolic blood pressure during TENS treatment at identical pacing rates indicated a decreased afterload. An increased coronary flow to ischemic areas in the myocardium was supported by the fact that the rate pressure product during anginal pain increased during TENS.
journal_name
Painjournal_title
Painauthors
Mannheimer C,Carlsson CA,Vedin A,Wilhelmsson Cdoi
10.1016/0304-3959(86)90058-8subject
Has Abstractpub_date
1986-09-01 00:00:00pages
291-300issue
3eissn
0304-3959issn
1872-6623pii
00006396-198609000-00003journal_volume
26pub_type
临床试验,杂志文章相关文献
PAIN文献大全abstract：:Oxytocin (OT), known for its neurohormonal effects around birth, has recently been suggested for being a critical determinant in neurodevelopmental disorders. This hypothalamic neuropeptide exerts a potent analgesic effect through an action on the nociceptive system. This endogenous control of pain has an important ad...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001375
更新日期：2018-12-01 00:00:00
abstract：:Microvascular decompression (MVD) of cranial nerves has become an established treatment for trigeminal and (vago)glossopharyngeal neuralgia and for hemifacial spasm. The authors present the case of a 64-year-old man who had a 3.5-year history of severe, drug-resistant hemibody pain with sensory and autonomic disturban...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2014.04.023
更新日期：2014-08-01 00:00:00
abstract：:Amitriptyline, a non-selective noradrenaline (NA) and 5-hydroxytryptamine (5-HT) reuptake inhibitor, has recently been demonstrated to produce a peripheral antinociceptive action in an inflammatory (formalin test) and a neuropathic pain model (spinal nerve ligation). In the present study, we determined whether desipra...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(99)00043-3
更新日期：1999-08-01 00:00:00
abstract：:Previous evidence suggests that, in adult animals, nerve growth factor (NGF) can induce hyperalgesia, and may be an endogenous mediator in some persistent pain states. Here we have studied the effects of single intradermal injections of 50-500 ng of human recombinant NGF into the plantar skin of adult rat hindpaws. We...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(95)00024-M
更新日期：1995-10-01 00:00:00
abstract：:Injection of a dilute solution of formalin into a rat hindpaw produces a biphasic nociceptive response consisting of an early phase during the first 5 min after formalin injection and a later phase starting after 15 min and lasting for 40-50 min. The period between the two phases of nociceptive responding is generally...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(99)00033-0
更新日期：1999-07-01 00:00:00
abstract：:Unilateral intraplantar injection of Freund's complete adjuvant (FCA) into 1 hind paw of rats was used as a model of peripheral inflammation and persistent pain in order to examine time course effects of a continuous barrage of nociceptive input on the second-messenger transducing systems in the spinal cord. cAMP, cGM...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(94)90185-6
更新日期：1994-07-01 00:00:00
abstract：:This report describes a placebo-controlled study of transcutaneous electrical nerve stimulation (TENS) applied to the contralateral lower leg and outer ears of an amputee with non-painful phantom sensations. The subject received TENS or placebo stimulation on separate sessions in which baseline periods of no stimulati...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/0304-3959(89)90098-5
更新日期：1989-03-01 00:00:00
abstract：:Dysmenorrhea is the most prevalent gynecological disorder in women of child-bearing age. Dysmenorrhea is associated with central sensitization and functional and structural changes in the brain. Our recent brain morphometry study disclosed that dysmenorrhea is associated with trait-related abnormal gray matter (GM) ch...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2013.05.022
更新日期：2013-09-01 00:00:00
abstract：:Phantom urinary phenomena are a relatively rare disease entity. Literature search has revealed only one case following cystectomy, seven cases following spinal cord injury and several other cases in hemodialysis patients. This report presents a case of painful phantom bladder following cystectomy for chronic kidney an...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(79)90011-3
更新日期：1979-10-01 00:00:00
abstract：:Genetic polymorphisms result in absent enzyme activity of CYP2D6 (poor metabolizers, PM) in about 10% of the Caucasian population. This study investigates whether the PM genotype has an impact on the response to tramadol analgesia in postoperative patients. A prospective study design was used and 300 patients recoveri...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(03)00212-4
更新日期：2003-09-01 00:00:00
abstract：:This study characterized the pain reported in a selected group of obstetrical patients in labor and compared the pain experienced at 2 stages of dilation, dilation of 2-5 cm and of 6-10 cm. Pain was defined as the perception of an unpleasant sensory and emotional experience with multidimensional factors that evoke beh...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(89)90215-7
更新日期：1989-09-01 00:00:00
abstract：:The main goal of current pain management approaches is to increase the patients' quality of life by improving pain coping skills and by reducing the levels of disability in daily life, often despite persistent pain. Direct measurement of quality of life is of crucial importance in economic evaluation research, in whic...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0304-3959(98)00232-2
更新日期：1999-03-01 00:00:00
abstract：:The objective of this study was to examine pain as a predictor of frailty over 18 years of follow-up among older Mexican Americans who were nonfrail at baseline. Data were from a prospective cohort study of 1545 community-dwelling Mexican Americans aged ≥67 years from the Hispanic Established Populations for the Epide...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001711
更新日期：2020-01-01 00:00:00
abstract：:The aim of the present study was to test (1) whether muscle pain is influenced by temporal and spatial summation, and (2) whether sequential noxious muscle stimuli applied at hourly interstimulus-intervals could produce an increased sensation of pain due to central hyperexcitability. In the study eleven healthy men we...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/s0304-3959(96)03243-5
更新日期：1997-01-01 00:00:00
abstract：:Self-hypnosis was taught to 5 highly hypnotisable patients referred to Auckland Hospital Pain Clinic. Evaluation included the Illness Self-Concept Repertory Grid (ISCRG) and follow-up was at 1 and 6 months post treatment. Consensus grids indicated the subjects initially identified with physical illness but this associ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(88)90223-0
更新日期：1988-11-01 00:00:00
abstract：:Migraine encompasses a broader spectrum of sensory symptoms than just headache. These "other" symptoms, eg, sensory phobias, cognitive and mood changes, allodynia, and many others indicate an altered sensitivity to sensory input which can be measured, in principle, by quantifying sensory threshold changes longitudinal...
journal_title：Pain
pub_type： 杂志文章,评审
doi：10.1097/j.pain.0000000000001531
更新日期：2019-07-01 00:00:00
abstract：:Calcitonin gene-related peptide (CGRP) is a 37-amino acid peptide found primarily in the C and Aδ sensory fibers arising from the dorsal root and trigeminal ganglia, as well as the central nervous system. Calcitonin gene-related peptide was found to play important roles in cardiovascular, digestive, and sensory functi...
journal_title：Pain
pub_type： 杂志文章,评审
doi：10.1097/j.pain.0000000000000831
更新日期：2017-04-01 00:00:00
abstract：:The purpose of this study was to examine the utility of the pain map as a pain assessment tool in frail nursing home residents. The study was conducted in two phases. In Phase 1, nursing home staff's knowledge of the locations of resident pain complaints was examined. We found significant deficiencies in this knowledg...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/s0304-3959(98)00059-1
更新日期：1998-05-01 00:00:00
abstract：:(1) Quantitative measurements of somatosensory thresholds and skin temperature were made before (24 cases), 3-5 days after (12 cases), and 6 months after (11 cases) successful radiofrequency thermocoagulation of the proximal root and gasserian ganglion in 24 cases of idiopathic trigeminal neuralgia (TGN), 18 of whom h...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(90)91121-X
更新日期：1990-03-01 00:00:00
abstract：:Injection of high-dose of morphine into the spinal lumbar intrathecal (i.t.) space of rats elicits a nociceptive behavioural syndrome characterized by periodic bouts of spontaneous agitation and severe vocalization. The induced behavioural response such as vocalization and agitation was observed dose-dependently by i....
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(03)00296-3
更新日期：2003-12-01 00:00:00
abstract：:We previously reported that morphine fails to produce analgesic tolerance when administered in the presence of formalin-induced pain. The hypothalamic-pituitary-adrenal (HPA) axis is known to respond to stressful stimuli, including pain. To examine whether the blockade of tolerance by pain is related to HPA activity, ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(95)00069-0
更新日期：1995-12-01 00:00:00
abstract：:The present study investigated whether the level of cognitive impairment (CI) affects acute pain behavior and how it is manifested. Participants were 159 individuals (mean age 42+/-12), 121 with CI (divided into four groups according to the level of CI: mild, moderate, severe, profound) and 38 with normal cognition (c...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/j.pain.2006.04.031
更新日期：2006-10-01 00:00:00
abstract：:VGF (nonacronymic) is a granin-like protein that is packaged and proteolytically processed within the regulated secretory pathway. VGF and peptides derived from its processing have been implicated in neuroplasticity associated with learning, memory, depression, and chronic pain. In sensory neurons, VGF is rapidly incr...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2014.03.012
更新日期：2014-07-01 00:00:00
abstract：:This study reports a 9-18 month follow-up of a randomised controlled trial of pain management programmes for chronic, non-malignant pain. Twenty-two inpatients, 18 outpatients and 12 control subjects completed the follow-up assessments. Significant treatment effects were demonstrated by the inpatient group on pain rat...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0304-3959(92)90110-W
更新日期：1992-07-01 00:00:00
abstract：:Caffeine is frequently added to mild analgesic preparations but its effect when used alone on pain has never been studied in humans. Using a double-blind placebo-controlled multiple crossover design, 53 patients with non-migrainous headaches were given placebo, acetaminophen, 2 doses of caffeine and 2 combinations of ...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/0304-3959(91)90129-L
更新日期：1991-02-01 00:00:00
abstract：:Neuropathic pain may be effectively relieved by electric stimulation of the spinal cord (SCS). However, the underlying mechanisms for the ensuing pain relief are poorly understood. In a rat model of neuropathy displaying hypersensitivity to innocuous tactile stimuli, (allodynia), we have earlier demonstrated that SCS ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(97)00077-8
更新日期：1997-10-01 00:00:00
abstract：:Movement is changed in pain, but the mechanisms remain unclear. Key questions are unresolved such as whether activation can be inhomogeneously distributed within a muscle in a manner that is specific to the location of noxious input. This study addressed this question using high-density electromyography (EMG) to study...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001317
更新日期：2018-11-01 00:00:00
abstract：:To inform case definition for neck/shoulder pain in epidemiological research, we compared levels of disability, patterns of association, and prognosis for pain that was limited to the neck or shoulders (LNSP) and more generalised musculoskeletal pain that involved the neck or shoulder(s) (GPNS). Baseline data on muscu...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000000477
更新日期：2016-05-01 00:00:00
abstract：:A variety of molecules released by inflammatory reactions in the dorsal root and dorsal root ganglion (DRG) may play important roles in the pathology of neuronal abnormalities in lumbar disc herniation. In order to elucidate the pathophysiological mechanisms of painful radiculopathy, secondary to lumbar disc herniatio...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(02)00068-4
更新日期：2002-09-01 00:00:00
abstract：:The relationship was investigated between algogenic potential of gallbladder pathology and occurrence/extent of sensory and trophic changes in the referred area. Five groups of subjects were studied, with: symptomatic gallbladder calculosis (3-20 colics); asymptomatic calculosis; symptomatic gallbladder shape abnormal...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2004.12.024
更新日期：2005-03-01 00:00:00
