Location-specific responses to nociceptive input support the purposeful nature of motor adaptation to pain.

abstract：:Back pain is a leading cause of disability. Previous research suggests that modifiable risk factors influence recovery from back pain, and practice guidelines recommend integrating such factors within primary care management. Toward this goal, a brief, multidimensional questionnaire, the STarT Back Tool, was designed ...

journal_title：Pain

authors： Wideman TH,Hill JC,Main CJ,Lewis M,Sullivan MJL,Hay EM

更新日期：2012-11-01 00:00:00

abstract：:Our objectives were to determine whether procedural pain and glucose exposure are associated with altered structural and functional brain development differently in preterm males and females, and neurodevelopment at 18-month corrected age. Fifty-one very preterm neonates (22 males; median [interquartile range] gestati...

journal_title：Pain

authors： Schneider J,Duerden EG,Guo T,Ng K,Hagmann P,Bickle Graz M,Grunau RE,Chakravarty MM,Hüppi PS,Truttmann AC,Miller SP

更新日期：2018-03-01 00:00:00

abstract：:Two hundred and sixty-three ambulatory patients older than 21 years of age who were attending clinics at an oncology hospital in San Juan, Puerto Rico, were studied. They completed a questionnaire (BQ-PR) that measures 8 concerns about reporting pain and using analgesics, such as fears of addiction and tolerance and t...

journal_title：Pain

authors： Ward SE,Hernandez L

更新日期：1994-08-01 00:00:00

abstract：:Primary neuronal cell bodies, whose peripheral axons comprised the cutaneous branch of the mylohyoid nerve or innervated the mandibular molar tooth pulp or the cornea, were labeled with HRP and their cross-sectional area was analyzed. Most of their cell bodies were smaller than 1000 microns2 in cross-sectional area an...

journal_title：Pain

authors： Sugimoto T,Takemura M,Wakisaka S

更新日期：1988-03-01 00:00:00

abstract：:The present study is a long-term report on 69 patients undergoing unilateral percutaneous cervical cordotomy for vertebral pain due to neoplastic bone metastases. The pain was unilateral or bilateral and was characterised by a chronic and/or an incident component. Seventy-one per cent (49/69) of the patients benefitte...

journal_title：Pain

authors： Ischia S,Luzzani A,Ischia A,Pacini L

更新日期：1984-06-01 00:00:00

abstract：:Despite the presence of pathology in cancer pain, the pain experience in adult cancer patients cannot be totally explained by the extent of such pathology. Unlike chronic benign pain very little research on the role of biobehavioral factors has been conducted to help explain this paradox. The literature on the role of...

journal_title：Pain

authors： Dalton JA,Feuerstein M

更新日期：1988-05-01 00:00:00

abstract：:Neuroimaging studies of patients with chronic pain have shown that neurotransmitter abnormalities, including increases in glutamate and decreases in GABA, could be responsible for the cortical hyperactivity and hyperalgesia/allodynia observed in some pain conditions. These finding are particularly evident in the insul...

journal_title：Pain

authors： Watson CJ

更新日期：2016-10-01 00:00:00

abstract：:This study evaluated the pre-emptive analgesic effect of intravenous (i.v.) ketorolac (KET) for total hip replacement (THR). Sixty patients who underwent surgery for THR under general anesthesia were randomly allocated to 3 groups. Two i.v. injections were administered: one before induction and one after surgery. The ...

journal_title：Pain

authors： Fletcher D,Zetlaoui P,Monin S,Bombart M,Samii K

更新日期：1995-05-01 00:00:00

abstract：:Two cases of reflex sympathetic dystrophy in the upper extremity of patients with traumatic cervical spinal cord injuries are reported. Both patients had very incomplete lesions with early neurological recovery, suggesting an underlying central cord syndrome. Although reflex sympathetic dystrophy is often seen followi...

journal_title：Pain

authors： Wainapel SF

更新日期：1984-04-01 00:00:00

abstract：:The facial expression of pain plays a crucial role in pain communication and pain diagnostics. Despite its importance, it has remained unknown which dimensions of pain (sensory and/or affective) are encoded in the face. To answer this question, we used a well-established cognitive strategy (suggestions) to differentia...

journal_title：Pain

authors： Kunz M,Lautenbacher S,LeBlanc N,Rainville P

更新日期：2012-02-01 00:00:00

abstract：:This study was designed to investigate the relative efficacy of cognitive-behavioral group treatment, including relaxation training, in comparison with a control condition in a sample of 20 outpatients with chronic low back pain. Subjects in both conditions also received the same physiotherapy back-education and exerc...

journal_title：Pain

authors： Nicholas MK,Wilson PH,Goyen J

更新日期：1992-03-01 00:00:00

abstract：:The primary purpose of this study was to examine the extent to which specific patient attitudes and beliefs about medical care and self-care for back pain predict future healthcare use. An automated database allowed examination of the predictive relationships in two primary care patient samples. In general, beliefs th...

journal_title：Pain

authors： Saunders KW,Von Korff M,Pruitt SD,Moore JE

更新日期：1999-11-01 00:00:00

abstract：:The current investigation studied the effectiveness of a secondary prevention program for nurses with back pain who were deemed at risk for developing a chronic problem. A 2 X 3 repeated measures design was employed with 2 groups and 3 assessment periods. The treatment group received an intervention designed to reduce...

journal_title：Pain

authors： Linton SJ,Bradley LA,Jensen I,Spangfort E,Sundell L

更新日期：1989-02-01 00:00:00

abstract：:Injection of high-dose of morphine into the spinal lumbar intrathecal (i.t.) space of rats elicits a nociceptive behavioural syndrome characterized by periodic bouts of spontaneous agitation and severe vocalization. The induced behavioural response such as vocalization and agitation was observed dose-dependently by i....

journal_title：Pain

authors： Watanabe C,Sakurada T,Okuda K,Sakurada C,Ando R,Sakurada S

更新日期：2003-12-01 00:00:00

abstract：:Mechanical allodynia is pain caused by normally innocuous mechanical stimuli and is a cardinal and intractable symptom of neuropathic pain. Roles of low-threshold mechanoreceptors (LTMRs), including Aβ fibers, in mechanical allodynia have previously been proposed, but the necessity and sufficiency of LTMRs in allodyni...

journal_title：Pain

authors： Tsuda M

更新日期：2019-05-01 00:00:00

abstract：:The blockade of spinal glycine receptors with intrathecal (i.t.) strychnine produces segmentally-localized allodynia in the rat; a reversible and highly reproducible effect that is attained without peripheral or central nerve injury. We investigated the effect of i.v. mexiletine, an orally active congener of lidocaine...

journal_title：Pain

authors： Khandwala H,Hodge E,Loomis CW

更新日期：1997-09-01 00:00:00

abstract：:Although EMLA is known to be an effective topical anesthetic, its rate of success is unknown. Indeed, researchers have suggested that EMLA may fail with young and apprehensive children. Therefore, the objectives of this study were to assess EMLA's rate of success as well as factors which predict success. A double-blin...

journal_title：Pain

authors： Lander J,Hodgins M,Nazarali S,McTavish J,Ouellette J,Friesen E

更新日期：1996-01-01 00:00:00

abstract：:Visceral inflammation is thought to play an important role in the sensitization of low and high threshold mechanosensory and polymodal afferents and to recruit silent nociceptors. Yet, little is known about the potential role of the mediators involved in nociceptor sensitization to mechanical stimulation as compared t...

journal_title：Pain

authors： Roza C,Reeh PW

更新日期：2001-09-01 00:00:00

abstract：:Although many patients with multiple sclerosis (MS) complain of trigeminal neuralgia (TN), its cause and mechanisms are still debatable. In a multicentre controlled study, we collected 130 patients with MS: 50 patients with TN, 30 patients with trigeminal sensory disturbances other than TN (ongoing pain, dysaesthesia,...

journal_title：Pain

authors： Cruccu G,Biasiotta A,Di Rezze S,Fiorelli M,Galeotti F,Innocenti P,Mameli S,Millefiorini E,Truini A

更新日期：2009-06-01 00:00:00

abstract：:Fine myelinated (Aδ) nociceptors are responsible for fast, well-localised pain, but relatively little is known about their postsynaptic targets in the spinal cord, and therefore about their roles in the neuronal circuits that process nociceptive information. Here we show that transganglionically transported cholera to...

journal_title：Pain

authors： Baseer N,Al-Baloushi AS,Watanabe M,Shehab SA,Todd AJ

更新日期：2014-11-01 00:00:00

abstract：:Eight patients with established lower limb postamputation stump pain were given lumbar intrathecal fentanyl 25 micrograms and lidocaine 70 mg 2 weeks apart in an attempt to better understand the role of peripheral and central mechanisms in this condition. Baseline pain was recorded and then analgetic and side effects ...

journal_title：Pain

authors： Jacobson L,Chabal C,Brody MC,Mariano AJ,Chaney EF

更新日期：1990-02-01 00:00:00

abstract：:The role of 5-hydroxytryptamine (5-HT)(4), 5-HT(6), and 5-HT(7) receptors in formalin-induced secondary allodynia and hyperalgesia in rats was assessed. Formalin produced acute nociceptive behaviors (flinching and licking/lifting) followed by long-term secondary mechanical allodynia and hyperalgesia. Pretreatment (-10...

journal_title：Pain

authors： Godínez-Chaparro B,Barragán-Iglesias P,Castañeda-Corral G,Rocha-González HI,Granados-Soto V

更新日期：2011-03-01 00:00:00

abstract：:Moderate to severe chronic pain affects 1 in 5 adults and its impact increases with age. People with chronic pain that interferes with their lives have an increased risk of mortality. Identifying how interfering chronic pain can lead to mortality may highlight potential intervention strategies. This study uses a novel...

journal_title：Pain

authors： Smith D,Wilkie R,Croft P,Parmar S,McBeth J

更新日期：2018-06-01 00:00:00

abstract：:Recent meta-analyses have shown mindfulness-based interventions (MBIs) to be effective for chronic pain, but no pooled estimates of the effect of MBIs on acute pain are available. This meta-analysis was conducted to fill that gap. A literature search was conducted in 4 databases. Articles were eligible if they reporte...

journal_title：Pain

authors： Shires A,Sharpe L,Davies JN,Newton-John TRO

更新日期：2020-08-01 00:00:00

abstract：:Pain catastrophizing is a significant risk factor for patients with knee osteoarthritis (KOA) and thus is a target for many psychological interventions for pain. This study examined if interventions targeting sleep found to be effective in improving sleep in KOA also reduce pain catastrophizing measured as a trait thr...

journal_title：Pain

authors： Lerman SF,Finan PH,Smith MT,Haythornthwaite JA

更新日期：2017-11-01 00:00:00

abstract：:Endometriosis, an estrogen-dependent chronic inflammatory disease, is the most common cause of chronic pelvic pain. Here, we investigated the effects of linaclotide, a Food and Drug Administration-approved treatment for IBS-C, in a rat model of endometriosis. Eight weeks after endometrium transplantation into the inte...

journal_title：Pain

authors： Ge P,Ren J,Harrington AM,Grundy L,Castro J,Brierley SM,Hannig G

更新日期：2019-11-01 00:00:00

abstract：:The local anesthetic lidocaine was injected into the dentate gyrus (DG) of alert, unrestrained rats 10 min prior to investigation within the formalin test. Regional anesthesia of the DG resulted in a reduction of pain scores when administered contralateral to the site of subcutaneous formalin injection. The analgesic ...

journal_title：Pain

authors： McKenna JE,Melzack R

更新日期：1992-04-01 00:00:00

abstract：:Although trigeminal neuralgia and atypical facial pain can usually be distinguished on the basis of several well-established criteria, differential diagnosis is difficult in a small number of patients. The purpose of this study was to determine whether the McGill Pain Questionnaire (MPQ) is capable of discriminating b...

journal_title：Pain

authors： Melzack R,Terrence C,Fromm G,Amsel R

更新日期：1986-12-01 00:00:00

abstract：:A 1-year follow-up of two preadolescent age cohorts with musculoskeletal pain at least once a week was conducted to analyze predictive factors for the persistence of musculoskeletal pain. Of the 564 children with pain at baseline, representing one third of the sample studied, 515 (91.3%) could be followed and 452 (80....

journal_title：Pain

authors： Mikkelsson M,Salminen JJ,Sourander A,Kautiainen H

更新日期：1998-07-01 00:00:00

abstract：:A series of 37 patients with chronic pain was investigated with regard to neurologic and psychiatric variables. Twenty of the patients were classified as having mainly organic (= somatogenic) pain syndromes while 17 patients were rather suffering from psychogenic pain syndromes. Samples of lumbar cerebrospinal fluid (...

journal_title：Pain

authors： Almay BGL,Johansson F,Von Knorring L,Terenius L,Wahlstrom A

更新日期：1978-08-01 00:00:00