Aluminum transport and dialysance during haemodialysis.

Abstract:

:Aluminum transfer and dialysance during haemodialysis and plasma aluminum concentrations in haemodialysis patients were examined. Plasma aluminum in 30 volunteer outpatients tended to decrease after 5-hour dialysis (6.35 +/- 3.02 micrograms/dl before haemodialysis; 5.41 +/- 2.60 micrograms/dl after haemodialysis). The decrease was mainly due to diffusion despite haemoconcentration evidenced by a significant increase in the haematocrit and total plasma protein during dialysis. To study the changes resulting from diffusion, we measured aluminum in the arterial blood and in the dialysate at the inflow and outflow sites of the dialyzer. There was a non-significant decrease in the plasma aluminum of arterial blood from 6.20 +/- 2.90 to 5.64 +/- 2.55 micrograms/dl, but a significant increase in the dialysate aluminum from 0.38 +/- 0.18 micrograms/dl to 1.10 +/- 0.66 micrograms/dl. Aluminum diffused across the dialyzer from the blood to the dialysate in 23 cases and into the blood in 7 others. When aluminum dialysance is high, plasma aluminum can be removed to the dialysate during haemodialysis.

journal_name

Int Urol Nephrol

authors

Hosokawa S,Nishitani H,Nishio T,Imai T,Tomita Y,Tomoyoshi T,Sawanishi K,Yoshida O

doi

10.1007/BF02583037

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

89-100

issue

1

eissn

0301-1623

issn

1573-2584

journal_volume

20

pub_type

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