Abstract:
PURPOSE:The current study was conducted to determine the effects of coenzyme Q10 (CoQ10) supplementation on glycemic control and markers of lipid profiles risk in diabetic hemodialysis (HD) patients. METHODS:This randomized, double blind, placebo-controlled clinical trial was performed among 60 diabetic HD patients. Subjects were randomly allocated into two groups to take either 120 mg/day of CoQ10 supplements or placebo (n = 30 each group) for 12 weeks. RESULTS:After 12 weeks of intervention, CoQ10 supplementation, compared with the placebo, resulted in a significant decrease in serum insulin concentrations (- 2.5 ± 4.0 vs. + 2.8 ± 5.3 µIU/mL, P < 0.001), homeostasis model of assessment-estimated insulin resistance (- 0.9 ± 2.1 vs. + 1.2 ± 3.0, P = 0.002), and significant increase in the quantitative insulin sensitivity check index (+ 0.009 ± 0.01 vs. - 0.02 ± 0.05, P = 0.003). In addition, a trend toward a greater decrease in serum triglycerides (- 5 ± 53 vs. + 17 ± 44, P = 0.078) and VLDL-cholesterol levels (- 0.9 ± 10 vs. + 3 ± 9, P = 0.078) was observed in the CoQ10 group compared to the placebo group. We did not observe any significant effect of CoQ10 supplementation on fasting glucose, HbA1c and other lipid profiles compared with the placebo. CONCLUSIONS:Overall, our study supported that CoQ10 supplementation to diabetic HD patients for 12 weeks had beneficial effects on markers of insulin metabolism, but did not affect fasting glucose, HbA1c, and lipid profiles. Clinical registration http://www.irct.ir : IRCT2016081811763N30.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Fallah M,Askari G,Soleimani A,Feizi A,Asemi Zdoi
10.1007/s11255-018-1973-zsubject
Has Abstractpub_date
2018-11-01 00:00:00pages
2073-2079issue
11eissn
0301-1623issn
1573-2584pii
10.1007/s11255-018-1973-zjournal_volume
50pub_type
杂志文章,随机对照试验abstract::Evaluation of potential candidates for testosterone replacement therapy (TRT) includes a complete medical history, physical examination, and hormonal screening. The choice of testosterone assay is important in clinical decision making. TRT should, in theory, approximate natural endogenous production of the hormone. Th...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-010-9879-4
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:ADPKD is one of the most common inherited disorders, with high risk for end-stage renal disease. Numerous patients, however, have no relatives in whom this disorder is known and are unsure whether they may transmit the disease to their offsprings. The aim of this study was to evaluate whether germline mutati...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0125-0
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION:Impaired kidney function is common in kidney-transplanted patients and complications of chronic kidney disease (CKD), such as mineral and bone disorders (MBD) are also prevalent in this population. Similarly to other stages of CKD, increasing evidence supports the association between MBD and cardiovascular...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9631-0
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Duplication of the vas deferens is the identification of a second vas deferens within the spermatic cord; it is a rarely reported congenital anomaly. Duplicate vas deferens should not be confused with double vas deferens that describes ipsilateral renal agenesis with a blind ureter ending in the ejaculatory ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0042-7
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:To perform a systematic review and meta-analysis to evaluate the cardiovascular prevention effect of aspirin among patients with chronic kidney disease (CKD). METHODS:A comprehensive literature search was conducted in Embase, PubMed, and Cochrane library (up to March 2019) without language limitations. Randomi...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析
doi:10.1007/s11255-019-02350-8
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:Five-year kidney graft loss currently stands at about 30%. We evaluate the clinical utility of a blood test measuring donor-derived cell-free DNA that detects rejection earlier and, potentially, improves diagnostic and therapeutic accuracy. METHODS:In a randomized controlled experiment, we measured the clinica...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02491-1
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:We investigated the role of serum uric acid (sUA) and superoxide dismutase (SOD) as predictive factors for mortality in hemodialysis (HD) patients. METHODS:SOD, butyrylcholinesterase, and malondialdehyde were estimated spectrophotometrically and the other parameters by standard procedures. High-sensitive C-rea...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0233-x
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:To investigate the value of proliferating cell nuclear antigen (PCNA), Ki-67 antigen labelling indices and nucleolar organizer region (NOR) score in relation to histological grade, stage, recurrence and progression of the bladder tumor. MATERIALS AND METHODS:Tissue specimens from 77 bladder cancer patients ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1014452902976
更新日期:2002-01-01 00:00:00
abstract::Fibrosing cholestatic hepatitis (FCH) is an uncommon complication of renal transplantation. It is usually associated with hepatitis B and C viral infection. It is further rare in renal transplantation in absence of HBV and HCV infection. To the best of our knowledge, only three cases of FCH in renal transplantation, w...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-004-6196-9
更新日期:2004-01-01 00:00:00
abstract::The authors describe a case of ureteral fibroma. The aetiology, clinical symptomatology and diagnosis are discussed, and differentiation between benign and malignant lesions is emphasized. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02552113
更新日期:1992-01-01 00:00:00
abstract:AIM:To investigate the correlation of renal tubular inflammatory and injury markers with renal uric acid excretion in chronic kidney disease (CKD) patients. METHODS:Seventy-three patients with CKD were enrolled. Fasting blood and morning urine sample were collected for routine laboratory measurements. At the same time...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02447-5
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:Varicocele is among the leading causes of male infertility. Despite decades of research, its pathogenesis is still unclear. S100A12 is a member of the S100 family of calcium-binding proteins with principal extracellular activities. It is secreted by activated neutrophils and interacts with the multiligand recep...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-015-1188-5
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:Contrast-induced acute kidney injury (CI-AKI) is a serious complication in patients undergoing diagnostic cardiac angiography or percutaneous coronary intervention. We aimed to evaluate the preventive effects of left ventricular end-diastolic pressure (LVEDP)-guided hydration for the prevention of CI-AKI in ...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-019-02235-w
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:The aim of the study was to evaluate the impact of magnesium (Mg) on the evolution of arterial calcifications in hemodialysis patients. PATIENTS AND METHODS:Seventy-two stable hemodialysis patients were randomly allocated to two groups: 36 administered a regimen containing magnesium carbonate plus calcium a...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-014-0751-9
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Patients with chronic kidney disease mineral and bone disorders (CKD-MBD) suffer high rates of morbidity and mortality, in particular related to bone and cardiovascular outcomes. The management of CKD-MBD remains challenging. The objective of this systematic survey is to critically appraise clinical practice...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-016-1436-3
更新日期:2017-02-01 00:00:00
abstract::Protein Z (PZ) is a vitamin K-dependent protein isolated from human and bovine plasmas. Although the exact role of PZ in the haemostatic system is presently unknown, it is suggested that PZ deficiency may cause bleeding tendency. Haemostatic alterations in end-stage renal failure (ESRF) are certainly complex and invol...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007179631603
更新日期:1999-01-01 00:00:00
abstract::Cyproterone acetate was given as monotherapy to 18 patients with advanced prostatic carcinoma at a weekly dose of 300 mg. Progression was observed in all of the patients; median time to progression was 35 months and median survival time was 48 months. Partial response, stabilization, progression and exitus rates by ye...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02551344
更新日期:1997-01-01 00:00:00
abstract::We report a case of asymptomatic spontaneous migration outside the ureter of a double pigtail ureteral stent. This previously undescribed complication confirms the need for regular follow-up of patients with indwelling stents. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-4757-1
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Water intake is important for preventing kidney stones. Small molecules water is a more active restructured water under magnetic field. Here, we studied the relation between small molecules water and crystal formation in the rat kidney. MATERIALS:The small molecules water was prepared by a water machine provid...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1769-6
更新日期:2018-02-01 00:00:00
abstract::In this study, 31 (30%) cases of urinary tract infection (UTI) of 103 patients with malnutrition, who were admitted to our hospital, were investigated prospectively. Our purpose was to determine the frequency of UTI, species of bacteria caused to infection and their antibiotic susceptibility in infants with malnutriti...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007104326689
更新日期:2000-01-01 00:00:00
abstract::The concentrations of prostaglandin E2 (PGE2), sodium, potassium and creatinine were determined in the blood and urine of 50 renal transplant recipients treated with cyclosporine A or azathioprine, as immunosuppressive agents, for at least one year post transplantation. Fourteen healthy subjects served as control grou...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550640
更新日期:1992-01-01 00:00:00
abstract::Orthostatic hypotension is very common in the elderly. It increases morbidity and is an independant predictor of all cause mortality. It is defined as a fall in systolic blood pressure greater than 20 mm Hg or a fall in diastolic blood pressure greater than 10 mm Hg within 3 minutes of standing. Symptoms include light...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-7663-7
更新日期:2005-01-01 00:00:00
abstract::We aimed to investigate whether high peripheral and cavernosal plasma levels of apolipoprotein-(a) [Lp (a)] is an indicator for vasculogenic erectile dysfunction. We determined Lp (a), total cholesterol (TC), triglyceride (TG) and high density lipoprotein (HDL) levels in peripheral and cavernosal blood in 39 patients ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550575
更新日期:1998-01-01 00:00:00
abstract::To compare the anti-inflammatory effectiveness of corticotherapy and nonsteroid anti-inflammatory drugs (NSAID), we examined 126 infertile men with infectious aetiology. Seventy-seven patients were on corticotherapy and antibiotherapy (thirty-eight patients on high-dose and thirty-nine patients on low-dose corticother...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007184125900
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Cardiovascular disease is the most common cause of death in patients with chronic kidney disease (CKD). Epicardial adipose tissue (EAT) is an independent predictor of cardiovascular disease in the general population, and usually increases in the patients with cardiovascular disease risk. The change of EAT in...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02575-y
更新日期:2020-12-01 00:00:00
abstract::The authors report a rare case of imperforate anus as a congenital anomaly. Early diagnosis and close follow up are emphasized, in order to prevent the development of complications which may last for a lifetime. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549605
更新日期:1991-01-01 00:00:00
abstract::A patient with bladder carcinoma, subjected to cystectomy and bilateral ureterosigmoidostomy, survived for the length of 31 years. The Coffey method of anastomosis was applied in a form modified by the authors. The patient succumbed to acute circulatory insufficiency at the age of 85. Metastases were not discovered ei...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02081864
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:To evaluate the surgical feasibility and postoperative cosmesis of a novel transumbilical laparoendoscopic single-site (LESS) surgical approach involving Y-shaped incisions and three-flap umbilicoplasty in urachal remnant patients. METHODS:Patients with symptomatic urachal remnants who underwent either convent...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02746-x
更新日期:2021-01-02 00:00:00
abstract::Semen analysis and immunofluorescent antisperm antibodies were tested in 65 patients with varicocele. The mean sperm count and motility values in our study were 36.8 +/- 2.9 million per ml and 38.4 +/- 2.5 per cent, respectively. Both parameters were found not to differ significantly in three grades of varicocele. Imm...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02089408
更新日期:1985-01-01 00:00:00
abstract::Between 1985 and 1989, 54 boys underwent a MAGPI procedure. Excellent cosmetic and functional results were achieved in 94% of our cases in the early period. In order to assess the long-term results of this procedure, 41 boys attended long-term re-evaluation between 6 and 40 (mean 29) months postoperatively. MAGPI was ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549850
更新日期:1991-01-01 00:00:00