Abstract:
:Considering the aging dialysis population of today, increasing our knowledge about the nature, diagnosis and the treatment of bone mineral density (BMD) problems in end-stage renal disease (ESRD) patients deserves more attention. Osteoporosis is basicly defined as a decrease in bone mass. Large epidemiological studies in general population have identified several risk factors for osteoporosis including advancing age, female gender, white race, decreased calcium intake, gastric acid suppression therapy, sedentary lifestyle, premature loss of gonadal function, decreased estrogen secretion, thin body habitus, decreased physical activity, cigarette smoking, alcohol abuse, excess glucocorticoid exposure, and possibly some genetic factors. Osteoporosis in ESRD patients is only a part of a wider spectrum of metabolic bone problems, namely uremic osteodystrophy. Therefore, its diagnosis, management and follow-up may differ from the general population and an individualization of diagnosis and definition for dialysis population may be necessary. However, standard diagnostic tools such as dual energy X-ray absorptiometry (DEXA) have been widely used for the assessment of bone mineral deficiency status in ESRD patients. Regardless of the methods, most of the studies are in concordance with a reduced BMD in HD and PD patients. Dialysis patients are known to be at increased risk for low-trauma fractures. Thinning of cortical bone, which is responsible for the largest contribution toward reduced bone mineral content in chronic renal failure results in increased fracture risk. In either normal population and dialysis patients, fracture risk is increased with age. But in dialysis patients, besides age, several other factors may also affect the degree of bone mineral deficiency, and age-BMD relationship may be blunted. Female sex, in hemodialysis patients is negatively associated with total hip BMD. While several studies have been unable to demonstrate any association between BMD and PTH levels, larger body size has been shown to have a significant positive effect on BMD in both hemodialysis and peritoneal dialysis patients. Although they have been used in small groups of chronic kidney disease (CKD) and ESRD patients, because of their potential nephrotoxicity and hypocalcemic effects, use of biphosphonates in renal patients is questionable. Currently, bone biopsy, in order to exclude adynamic bone disease is recommended before beginning treatment with bisphosphonates in chronic kidney disease and dialysis patients.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Ersoy FFdoi
10.1007/s11255-006-9109-2subject
Has Abstractpub_date
2007-01-01 00:00:00pages
321-31issue
1eissn
0301-1623issn
1573-2584journal_volume
39pub_type
杂志文章,评审abstract:UNLABELLED:Furosemide test is a simple and useful test of renal physiology used to evaluate the capability of the collecting ducts to secrete potassium under the effect of serum aldosterone. Its behaviour pattern has been established in children and young adults but not described in very old healthy people, which we ex...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9547-8
更新日期:2010-03-01 00:00:00
abstract::We report a 40-year-old lady who presented with severe headaches, persistent microscopic haematuria and hypertension requiring anti-hypertensive medication. Investigations for secondary hypertension were all normal except for a CT scan. This indicated a complex cystic lesion, measuring 2.4 x 5 x 10 cms , arising from ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9085-6
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Smoking habit is the major risk factor for bladder cancer (BC), related to about 50% of these tumors; however, the tobacco dose-effect impact on BC immune treatment is underexplored. This study evaluates the impact of smoke load on non-muscle invasive bladder cancer (NMIBC) prognosis after intravesical BCG. ME...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02438-6
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:There is evidence that chronic local ischemia may be one possible etiology of prostatic atrophy (PA). Our aim was to study the expression of hypoxia induced factors in areas of PA. DESIGN:The immunohistochemical expression of hypoxia-inducible factor-1 alpha (HIF-1) and vascular endothelial growth factor (V...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-6657-4
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:Comorbidity has a significant impact on the health status and treatment outcome of a patient. The Charlson comorbidity index (CCI) is a frequently used scoring system, which evaluates the prognosis based on the patient's comorbid conditions. The aim of this study was to evaluate the usefulness of CCI in predict...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02499-7
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to assess the influence of anemia on the risk of developing contrast-induced nephropathy after percutaneous coronary angioplasty. METHODS:Serum creatinine values were measured before and within 48 h after the administration of contrast agents. Contrast-induced nephropathy (C...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0340-8
更新日期:2013-08-01 00:00:00
abstract::This is the first prospective study to investigate the association between kidney stones, bone mineral density, serum testosterone, colon cancer and O. formigenes colonization. 40 kidney stone patients and 85 controls were enrolled. O. formigenes colonization was established. BMD was examined from T- and Z-scores usin...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02627-3
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:We describe a new technique that can easily be used as a tension-free practical alternative in closing the renal defects resulting after open partial nephrectomy (PN). METHODS:A new technique (called "lipocorticoplasty") where "wrapped fatty tissue" was placed in the tumor crater to close the renal defects t...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9899-8
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Water intake is important for preventing kidney stones. Small molecules water is a more active restructured water under magnetic field. Here, we studied the relation between small molecules water and crystal formation in the rat kidney. MATERIALS:The small molecules water was prepared by a water machine provid...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1769-6
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:The natural history and optimal management strategy for men with human immunodeficiency virus (HIV) and prostate cancer remain to be definitively characterized. This study was conducted to evaluate the clinical characteristics and outcomes of HIV-seropositive men treated with robotic-assisted radical laparoscop...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1338-4
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:To examine the survival effect of treatment delays from the time of confirmed diagnosis of prostate cancer to first treatment in an Australian population. METHODS:Three thousand one hundred and forty patients were identified from the South Australian Prostate Cancer Clinical Outcomes Collaborative database ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1508-z
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:To evaluate the effect of masturbation on the spontaneous expulsion of distal ureteral stones 5-10 mm in size. MATERIAL AND METHODS:A total of 128 men with distal ureteral stones were randomly divided into 3 groups. All patients received standard medical therapy. Patients in group 1 (n = 43) were instructed to...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02672-y
更新日期:2020-10-07 00:00:00
abstract:INTRODUCTION:To find the most beneficial method, we assessed patient comfort and morbidity rates during prostate biopsy procedures performed using periprostatic nerve blockade, unilateral pudendal nerve blockade, intrarectal lidocaine gel, and a combination of periprostatic nerve blockade and intrarectal lidocaine gel....
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9237-3
更新日期:2008-01-01 00:00:00
abstract::Serum renin concentration (SRC) was determined in 97 hypertensive patients under basal conditions and during stimulation of renin secretion. Renin secretion was stimulated by upright posture and by either of the following means: (a) diet containing 20 mEq Na/24 hours for 3 days; (b) 300 mg i.v. diazoxide injections; (...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082246
更新日期:1976-01-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of the calcineurin inhibitors (CNIs) cyclosporine (CyA) and tacrolimus (TAC) in the induction and maintenance treatment of lupus nephritis (LN). METHODS:The Cochrane library, PubMed, Embase, and CENTRAL databases were searched and reviewed up to February 2015. Randomized con...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11255-015-1201-z
更新日期:2016-05-01 00:00:00
abstract::The aim of this study was to investigate the relationship between microvessel density (MVD), positive and negative angiogenic factors, and established prognostic factors in prostate cancer (PC), and, to clarify the effect of angiogenic factors to angiogenesis. The vascularization of neoplastic, non-neoplastic prostate...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9144-z
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Chronic kidney disease is independently associated with an increased risk of cardiovascular events; however, the relationship between the glomerular filtration rate (GFR) and coronary artery disease (CAD) in patients undergoing coronary angiography has yet to be fully elucidated. METHODS:This retrospective stu...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0070-3
更新日期:2012-08-01 00:00:00
abstract::Artificial insemination (ADI) has been carried out with donor semen since 1984. Following artificial insemination 14 women out of 27 became pregnant in 1984, 30 women out of 57 in 1985 and 33 women out of 56 until October 1, 1986. The cycles were monitored. Serum LH and oestradiol levels were determined every day from...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549573
更新日期:1988-01-01 00:00:00
abstract::Varicocele, the leading cause of male infertility, can impair sperm quality and fertility via various oxidative stress mechanisms. An imbalance between excessive reactive oxygen species production and antioxidant protection causes alterations in nuclear and mitochondrial sperm DNA, thus rendering a subset of varicocel...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-018-1839-4
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide and will lead some unfavorable outcomes such as end-stage renal disease. The efficacy of tonsillectomy remains controversial in both Asian and Caucasian ethnicity. Our meta-analysis was aiming at exploring its long-term efficacy and providin...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11255-016-1432-7
更新日期:2017-01-01 00:00:00
abstract::The aim of the present study was to examine subpreputial bacteriology and to compare it with the urine cultures of healthy male children. Seventy-two male children were divided into two groups as A and B according to age. In both groups preputial sac and urine cultures were taken simultaneously. Gram (+) enteric cocci...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007120520884
更新日期:2000-01-01 00:00:00
abstract::The aim of this report is to emphasize the use of methylene staining test and the Nd:YAG laser in the diagnosis and treatment of premalignant lesions and CIS of the bladder. The use of an appropriate solution of methylene blue (0.2% in 0.9 M NaCl for 15 min) permits the staining of premalignant areas and CIS, and thei...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02559739
更新日期:1989-01-01 00:00:00
abstract:AIM:Chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS) is a common disabling condition that is primarily associated with pain in the urogenital region and disturbances in urinary and sexual function. Chronic pelvic pain symptoms are the most common presentation, especially perineal, lower abdominal, testi...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9809-5
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:Noninvasive tests are needed for the diagnosis of chronic pelvic pain syndrome. We evaluated the significance of potassium chloride sensitivity test and urinary CTAB-precipitable uronate level in patients with chronic pelvic pain syndrome (CPPS). METHODS:We included 25 patients with interstitial cystitis (I...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-008-9463-3
更新日期:2009-01-01 00:00:00
abstract::An analysis of the ultrastructural features of 35 canine kidneys after hypothermic preservation in Rheomacrodex, Collins3 and Sacks II solutions, and subsequent autologous reperfusion for 2 to 3 hours is presented. Signs of irreversibility (intramitochondrial crista fragmentation, cell membrane rupture, detachment of ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02089353
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVES:Uroepithelium repair has always been the subject of discussion in urology surgeries. Using human amniotic membrane allograft has already proved to be useful in other fields. In this study, we use amniotic membrane to repair uroepithelium injuries in rabbits. METHODS:Twenty healthy rabbits underwent surgery ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9532-2
更新日期:2009-12-01 00:00:00
abstract::Sixty patients in Stages I and II of benign prostatic hyperplasia were treated with Peponen capsule. Out of them 26 took the drug for 10 months, 22 for at least 7, and 12 for at least 4 months. The daily dosage was 3 x 2 capsules in the first month and 3 x 1 capsule for the rest of the time. On the ground of urodynami...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549728
更新日期:1991-01-01 00:00:00
abstract::Segmental cystectomy or total cystectomy was performed in 26 patients with newly diagnosed stage T1, grade 3 transitional cell carcinoma of the bladder. Their histological specimens were assessed with regard to types of tumour cell spread, small vessel involvement and coexistent carcinoma in situ. Patients were follow...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550418
更新日期:1991-01-01 00:00:00
abstract::A clinical study was designed to investigate whether extracorporeal shock waves altered the urinary excretion of glycosaminoglycans and if they have a diagnostic value in determining the extent of the renal tissue damage. A total of 25 consecutive patients were treated for renal stone by extracorporeal shock wave lith...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:To investigate the effects of thermochemotherapy with mitomycin C (MMC) on normal rabbit bladder urothelium and to compare it with standard intravesical MMC and hyperthermia with normal saline. METHODS:Twenty-four male New Zealand rabbits, with a mean weight of 2.7 kg (in weight of 2.1–4.3 kg), were divided in...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-015-1139-1
更新日期:2016-01-01 00:00:00